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1. 发明授权

US5360863A Radiation curable compositions and their use 失效
标题翻译：可辐射固化组合物及其用途
公开(公告)号：US5360863A
公开(公告)日：1994-11-01
申请号：US101518
申请日：1993-08-02
申请人： Jurgen Meixner , Wolfgang Fischer , Pramod Gupta
发明人： Jurgen Meixner , Wolfgang Fischer , Pramod Gupta
IPC分类号： C08F299/04 , C08F283/01 , C08G63/52 , C08G63/676 , C08L67/06 , C09D4/00 , C09D167/06 , C09K3/10
CPC分类号： C08G63/676 , C08L67/06 , C09D167/06
摘要： The present invention relates to compositions which may be cured by radical polymerization at room temperature and containA) 20 to 100 parts by weight of .alpha.,.beta.-ethylenically unsaturated polyesters which are the reaction products ofa) a dicarboxylic acid component containing i) 40 to 100 carboxyl equivalent % of .alpha.,.beta. ethylenically unsaturated dicarboxylic acids and/or their anhydrides and ii) 0 to 60 carboxyl equivalent % of dicarboxylic acids and/or their anhydrides other than those set forth in i) withb) an alcohol component containing i) 25 to 100 hydroxyl equivalent % of alkoxylated 2-butene-1,4-diols having an average molecular weight 130 to 400 and ii) 0 to 75 hydroxyl equivalent % of mono- or poly- hydric alcohols having a molecular weight of 32 to 400 other than those set forth in i) wherein the amounts of a) and b) are chosen such that equivalent ratio of carboxyl groups to hydroxyl groups is no more than 1:1,B) 0 to 80 parts by weight of compounds containing (meth)acryloyl groups and/or vinyl ether groups,wherein the sum of the parts by weight of A) and B) is 100, based on the weight of components A) and B), provided that when components A) and B) are used in a weight ratio exceeding 9:1, component a) contains at least 90 carboxyl equivalent % of component ai) and component b) contains at least 40 hydroxyl equivalent % component bi). The present invention also relates to the use of these compositions as binders for coating, patching or sealing compositions and for the production of molded bodies.
摘要翻译：本发明涉及可在室温下通过自由基聚合固化并含有A）20至100重量份的α，β-烯属不饱和聚酯的组合物，其为a）包含i）的二羧酸组分的反应产物至100个羧基当量％的α，β-烯键式不饱和二羧酸和/或它们的酸酐，和ii）除i）中所列出的那些以外的二羧酸和/或其酸酐的0至60羧基当量％，b）含有 i）平均分子量为130〜400的25〜100个羟基当量％的烷氧基化2-丁烯-1,4-二醇，和ii）分子量为32的单 - 或多元醇的0〜75羟基当量％至a 400），其中选择a）和b）的量使得羧基与羟基的当量比不超过1:1，B）0至80重量份的化合物含有 g（甲基）丙烯酰基和/或乙烯基醚基，其中A）和B）的重量份之和为100，基于组分A）和B）的重量，条件是当组分A）和B ）以重量比超过9:1使用，组分a）含有至少90个羧基当量％的组分ai），组分b）含有至少40个羟基当量％组分bi）。本发明还涉及这些组合物作为粘合剂用于涂覆，修补或密封组合物以及用于生产模塑体的用途。

2. 发明申请

US20070142478A1 COMBINATION ANTIMICROBIAL COMPOSITION AND METHOD OF USE 审中-公开
标题翻译：组合抗微生物组合物及其使用方法
公开(公告)号：US20070142478A1
公开(公告)日：2007-06-21
申请号：US11610901
申请日：2006-12-14
申请人： Erning Xia , Hongna Wang , Srini Venkatesh , Pramod Gupta , Norman LaFrance
发明人： Erning Xia , Hongna Wang , Srini Venkatesh , Pramod Gupta , Norman LaFrance
IPC分类号： A61K31/155
CPC分类号： A61K31/155
摘要： Provided herein is a pharmaceutically acceptable composition comprising a biguanide containing antimicrobial agent and an additional antimicrobial agent. The invention further comprises topically administering the pharmaceutically acceptable composition to a patient in need of treatment.
摘要翻译：本文提供了包含含双胍的抗微生物剂和另外的抗微生物剂的药学上可接受的组合物。本发明还包括向需要治疗的患者局部施用药学上可接受的组合物。

3. 发明申请

US20050188436A1 Continuous culture of conifer embryogenic tissue 有权
标题翻译：针叶胚发生组织连续培养
公开(公告)号：US20050188436A1
公开(公告)日：2005-08-25
申请号：US11063416
申请日：2005-02-22
申请人： Pramod Gupta , Diane Holmstrom , Bonnie Larson
发明人： Pramod Gupta , Diane Holmstrom , Bonnie Larson
IPC分类号： A01H20060101 , A01H1/00 , A01H4/00 , A01H7/00 , C12N5/02 , C12N5/04 , C12N15/82
CPC分类号： A01H4/005 , A01H7/00 , C12N5/04
摘要： The present invention provides methods for multiplying conifer embryogenic tissue. The methods of the present invention each include the step of continuously culturing conifer embryogenic tissue in liquid multiplication medium for a period of time sufficient for the embryogenic tissue to multiply.
摘要翻译：本发明提供了用于倍增针叶胚发生组织的方法。本发明的方法各自包括在液体繁殖培养基中连续培养针叶树胚发生组织足以使胚发生组织繁殖的时间的步骤。

4. 发明申请

US20050113337A1 Enhancement of oral bioavailability of non-emulsified formulations of prodrug esters with lecithin 审中-公开
标题翻译：提高前药酯与卵磷脂的非乳化制剂的口服生物利用度
公开(公告)号：US20050113337A1
公开(公告)日：2005-05-26
申请号：US11014798
申请日：2004-12-13
申请人： Rajneesh Taneja , Dale Brinker , Jacqueline Briskin , Dilip Vishwasrao , Roberto Aponte , Pramod Gupta
发明人： Rajneesh Taneja , Dale Brinker , Jacqueline Briskin , Dilip Vishwasrao , Roberto Aponte , Pramod Gupta
IPC分类号： A61K9/00 , A61K9/16 , A61K9/20 , A61K31/343 , A61K31/4375 , A61K31/545 , A61K31/65 , A61K31/7048 , A61K31/685 , A61K31/57
CPC分类号： A61K31/4375 , A61K9/0095 , A61K9/1617 , A61K9/2013 , A61K9/2095 , A61K31/343 , A61K31/545 , A61K31/65 , A61K31/7048
摘要： A method for enhancing the oral bioavailability of a prodrug ester by formulating the ester as a non-emulsified formulation with lecithin; as well as a pharmaceutical composition of at least one antibiotic and lecithin in a non-emulsified formulation; a method of treating infections with the non-emulsified formulation, and a method for preparing tablets by direct compression of blends of drugs with lecithin are disclosed. Non-emulsified formulations include solids, tablets, capsules, lozenges, suspensions, elixirs and solutions, and exclude emulsions, liposomes, lipid matrix systems and micro-emulsions. A suitable prodrug ester is a cephalosporin β-lactam antibiotic such as cefditoren pivoxil, and a suitable non-emulsified formulation is a solid formulation.
摘要翻译：一种通过配制具有卵磷脂的非乳化制剂的酯来提高前药酯的口服生物利用度的方法; 以及非乳化制剂中至少一种抗生素和卵磷脂的药物组合物; 公开了用非乳化制剂治疗感染的方法，以及通过直接压制药物与卵磷脂的混合物制备片剂的方法。非乳化制剂包括固体，片剂，胶囊，锭剂，悬浮液，酏剂和溶液，并且不包括乳剂，脂质体，脂质基质体系和微乳液。合适的前药酯是头孢菌素β-内酰胺抗生素，例如匹戊头孢托仑，合适的非乳化制剂是固体制剂。

5. 发明授权

US06878661B1 Bimetallic-cyanide catalysts used for preparing polyether polyols 失效
标题翻译：用于制备聚醚多元醇的双金属氰化物催化剂
公开(公告)号：US06878661B1
公开(公告)日：2005-04-12
申请号：US09744357
申请日：1999-07-20
申请人： Pieter Ooms , Jörg Hofmann , Pramod Gupta , Walter Schäfer
发明人： Pieter Ooms , Jörg Hofmann , Pramod Gupta , Walter Schäfer
IPC分类号： C08G65/10 , C08G65/26 , B01J31/00
CPC分类号： B01J27/26 , C08G65/10 , C08G65/2663
摘要： The invention relates to novel double metal cyanide (DMC) catalysts for the preparation of polyether polyols by polyaddition of alkylene oxides to starter compounds containing active hydrogen atoms, wherein the catalyst contains a) double metal cyanide compounds, b) organic complex ligands other than c), and c) complex ligands formed by introduction of a glycidyl ether into the catalyst. The catalysts according to the invention have greatly increased activity in the preparation of polyether polyols.
摘要翻译：本发明涉及用于制备聚醚多元醇的新型双金属氰化物（DMC）催化剂，其通过将环氧烷加成到含有活性氢原子的起始化合物中，其中催化剂含有a）双金属氰化物化合物，b）除c以外的有机络合物配体），和c）通过将缩水甘油醚引入催化剂而形成的复合配位体。根据本发明的催化剂在制备聚醚多元醇中的活性大大增加。

6. 发明授权

US06858655B1 High-resilient polyurethane foams produced from polyether polyols 有权
标题翻译：由聚醚多元醇生产的高弹性聚氨酯泡沫
公开(公告)号：US06858655B1
公开(公告)日：2005-02-22
申请号：US10018332
申请日：2000-06-06
申请人： Jörg Hofmann , Pramod Gupta , Manfred Dietrich , Hansjürgen Rabe , Jürgen Grönen , Pieter Ooms
发明人： Jörg Hofmann , Pramod Gupta , Manfred Dietrich , Hansjürgen Rabe , Jürgen Grönen , Pieter Ooms
IPC分类号： C08G18/48 , C08G65/26 , C08G101/00 , C08G18/28
CPC分类号： C08G65/2663 , C08G18/4845 , C08G18/485 , C08G18/4866 , C08G2101/0008 , C08G2101/0083
摘要： Flexible polyurethane foams are produced from a polyisocyanate and a polyether polyol which has been alkoxylated in the presence of a double metal cyanide catalyst and that has at least one ethylene oxide-propylene oxide mixed block.
摘要翻译：柔性聚氨酯泡沫由多异氰酸酯和聚醚多元醇生产，所述多异氰酸酯和聚醚多元醇在双金属氰化物催化剂存在下被烷氧基化，并且具有至少一个环氧乙烷 - 环氧丙烷混合嵌段。

7. 发明授权

US06624321B2 Process for the preparation of polyether polyols 失效
公开(公告)号：US06624321B2
公开(公告)日：2003-09-23
申请号：US10277615
申请日：2002-10-22
申请人： Uwe Denninger , Jörg Hofmann , Pramod Gupta
发明人： Uwe Denninger , Jörg Hofmann , Pramod Gupta
IPC分类号： C07F506
CPC分类号： C08G65/2654 , B01J31/0211 , B01J31/0227 , B01J31/0228 , B01J31/0252 , B01J31/0255 , B01J31/0257 , B01J2231/48 , C07F5/069
摘要： The present invention relates to a process for the preparation of polyether polyols by the reaction of alkylene oxides and compounds containing active hydrogens, in the presence of specific Lewis acid metal compounds as catalysts, novel bis(perfluoroalkylsulfonic acid) compounds of Group 13 of the Periodic Table of the Elements, and to a process for the preparation thereof and the use thereof as catalysts for ring-opening polymerization of cyclic ethers.

8. 发明授权

US06458918B1 Method for producing partially crystalline polyether polyols 失效
标题翻译：部分结晶聚醚多元醇的制备方法
公开(公告)号：US06458918B1
公开(公告)日：2002-10-01
申请号：US09530304
申请日：2000-04-27
申请人： Walter Schäfer , Jörg Hofmann , Pramod Gupta , Hanns-Peter Müller , Harald Pielartzik
发明人： Walter Schäfer , Jörg Hofmann , Pramod Gupta , Hanns-Peter Müller , Harald Pielartzik
IPC分类号： C08G6512
CPC分类号： C08G65/269 , B01J31/068 , B01J31/165 , B01J31/2226 , B01J2231/48 , B01J2531/0216 , B01J2531/0219 , B01J2531/26 , B01J2531/31 , B01J2531/46 , B01J2531/62 , B01J2531/64 , B01J2531/70 , B01J2531/842 , B01J2531/845 , C08G65/12 , C08G65/2642 , C08G2250/00
摘要： The present invention relates to a process for the preparation of novel, partially crystalline polyether polyols with a functionality of ≧2, an average molecular weight Mn of 500 to 100,000 and a molar proportion of isotactic triads determining the crystallinity of >28%. The new polyether polyols are prepared by polymerizing alkylene oxides in the presence of a bimetallic :-oxoalkoxide modified with hydroxyl compounds.
摘要翻译：本发明涉及一种制备具有官能度> = 2，平均分子量Mn为500至100,000的新型部分结晶的聚醚多元醇和确定结晶度> 28％的全同立构三单元组的摩尔比例的方法。新的聚醚多元醇通过在用羟基化合物改性的双金属氧化物存在下聚合烯化氧来制备。

9. 发明授权

US06323375B1 Crystalline double metal cyanide catalysts for producing polyether polyols 有权
标题翻译：用于生产聚醚多元醇的结晶双金属氰化物催化剂
公开(公告)号：US06323375B1
公开(公告)日：2001-11-27
申请号：US09509979
申请日：2000-04-05
申请人： Jörg Hofmann , Pramod Gupta , Robert-Joseph Kumpf , Pieter Ooms , Walter Schäfer , Michael Schneider
发明人： Jörg Hofmann , Pramod Gupta , Robert-Joseph Kumpf , Pieter Ooms , Walter Schäfer , Michael Schneider
IPC分类号： C07C4311
CPC分类号： C08G65/2663 , B01J27/26
摘要： The present invention relates to highly active, substantially crystalline double metal cyanide (DMC) catalysts, a process for the preparation of these double metal cyanide catalysts, a process for producing polyether polyols by the polyaddition of alcohol ethers onto starter compounds containing active hydrogen atoms from these DMC catalysts, and to the polyether polyols produced by this process. The DMC catalysts of the invention comprise a) double metal cyanide compounds, b) organic complexing ligands, and c) functionalized polymers. These catalysts exhibit increased activity in the process for the production of polyether polyols.
摘要翻译：本发明涉及高活性，基本上结晶的双金属氰化物（DMC）催化剂，制备这些双金属氰化物催化剂的方法，通过将醇醚加成到含有活性氢原子的起始化合物上制备聚醚多元醇的方法这些DMC催化剂，以及通过该方法制备的聚醚多元醇。本发明的DMC催化剂包括a）双金属氰化物化合物，b）有机络合配体，和c）官能化聚合物。这些催化剂在制备聚醚多元醇的方法中表现出增加的活性。

10. 发明授权

US5672768A Low-odor, higher molecular weight polyether polyols, a process for producing them, and their use for the production of polymers, cosmetics and pharmaceutical products synthesized from polyether polyols 失效
标题翻译：低气味，高分子量的聚醚多元醇，其制备方法及其用于生产由聚醚多元醇合成的聚合物，化妆品和药物的用途
公开(公告)号：US5672768A
公开(公告)日：1997-09-30
申请号：US780760
申请日：1997-01-08
申请人： Pramod Gupta , Gundolf Jacobs , Joel Leuridan
发明人： Pramod Gupta , Gundolf Jacobs , Joel Leuridan
IPC分类号： A61K8/86 , A61K47/10 , A61Q19/00 , C08G18/48 , C08G65/02 , C08G65/06 , C08G65/26 , C08G65/30 , C08L71/02 , C07C43/11 , C07C43/18 , C07C43/20
CPC分类号： C08G65/30 , A61K47/10 , A61K8/86 , A61Q19/00
摘要： Low-odor, higher molecular weight polyether polyols are produced by purifying the polyether polyols at temperatures of 110.degree. to 150.degree. C. and pressures of 10 to 70 hPa with the addition of 5 to 30% by weight of water, wherein the water is passed in finely divided form, with a droplet diameter of about 5 to 100.mu., through the polyether polyols to be purified for a time of metered addition of 1 to 5 hours.
摘要翻译：通过在110℃至150℃的温度和10至70hPa的压力下纯化聚醚多元醇并加入5至30重量％的水来生产低气味的较高分子量的聚醚多元醇，其中水为通过聚醚多元醇以微细直径约5至100微米的形式通过待纯化的计时加入1至5小时的时间。

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