专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US6027648A Method of resolving a mixture of optical isomers 失效
标题翻译：拆分光学异构体混合物的方法
公开(公告)号：US6027648A
公开(公告)日：2000-02-22
申请号：US201740
申请日：1994-02-25
申请人： Jun Haginaka , Hiroo Wada , Hiroya Fujima , Toshinobu Miwa
发明人： Jun Haginaka , Hiroo Wada , Hiroya Fujima , Toshinobu Miwa
IPC分类号： C07B57/00 , C07K1/107 , C07K1/113 , C07K9/00 , C07K14/00 , C07K17/00 , C07K17/02 , C07K17/08 , C07K17/12 , C07K17/14 , B01D15/00 , B01D15/08
CPC分类号： C07B57/00 , C07K17/02 , C07K17/14
摘要： An optical isomer separating agent comprises a stationary phase in which the molecular structure of ovomucoid fixed to a carrier is partly modified, or a stationary phase in which ovomucoid having the molecule partly modified is fixed to a carrier is disclosed. A process for producing an optical isomer separating agent comprises the steps of immobilizing ovomucoid on a carrier and modifying the ovomucoid is disclosed. Furthermore a process for producing an optical isomer separating agent comprises the steps of modifying ovomucoid and immobilizing the modified ovomucoid on a carrier is disclosed.
摘要翻译：光学异构体分离剂包括其中固定在载体上的蛋白质类的分子结构被部分修饰的固定相或其中具有部分改性的分子的类粘蛋白固定在载体上的固定相。制造旋光异构体分离剂的方法包括以下步骤：将卵巢粘蛋白固定在载体上并修饰卵粘蛋白。此外，制造旋光异构体分离剂的方法包括以下步骤：将改变的卵巢粘蛋白和修饰的卵类粘蛋白固定在载体上。

2. 发明授权

US5670629A Ovoglycoprotein and agents for chromatographic separation containing same 失效
标题翻译：卵黄蛋白和含有其的色谱分离剂
公开(公告)号：US5670629A
公开(公告)日：1997-09-23
申请号：US397861
申请日：1995-03-02
申请人： Jun Haginaka , Hiroo Wada , Hiroya Fujima
发明人： Jun Haginaka , Hiroo Wada , Hiroya Fujima
IPC分类号： B01J20/32 , C07K14/465 , C07K1/00 , A23J1/00
CPC分类号： B01J20/29 , B01J20/286 , B01J20/3204 , B01J20/3208 , B01J20/3219 , B01J20/3221 , B01J20/3274 , C07K14/465 , B01J2220/54 , B01J2220/58 , Y10S530/827
摘要： An ovoglycoprotein has a molecular weight of 30,000 daltons which is determined by a matrix-assisted laser desorption ionization time-of-flight type mass spectrometer, an amino acid sequence of 15 residues from the N-terminal represented by Thr-Glu-Ser-Pro-Xaa-Ser-Ala-Pro-Leu-Val-Pro-Ala-Asp-Met-Asp (wherein Xaa represents a cysteine residue or an amino acid residue having a sugar chain linked thereto) (SEQ ID NO:1) and a sugar content of about 25% by weight and free of trypsin-inhibitory activity and a resolution agent for chromatography comprises a fixed phase which comprises a carrier and the foregoing ovoglycoprotein linked to the carrier. The agent for resolving optical isomers is not expensive, and is stable and highly resistant to deterioration by organic solvents, excellent in liquid-flow through properties, has a high sample-loading rate and permits efficient resolution of optical isomers of a chiral compound.
摘要翻译：卵磷脂蛋白的分子量为30,000道尔顿，其通过基质辅助激光解吸电离飞行时间型质谱仪测定，由Thr-Glu-Ser-Pro表示的N末端的15个残基的氨基酸序列 -Xaa-Ser-Ala-Pro-Leu-Val-Pro-Ala-Asp-Met-Asp（其中Xaa表示半胱氨酸残基或与其连接的糖链的氨基酸残基）（SEQ ID NO：1）和约25重量％的糖含量和没有胰蛋白酶抑制活性和用于色谱的分离剂包括固定相，其包含与载体连接的载体和前述卵糖蛋白。用于拆分光学异构体的试剂不是昂贵的，并且稳定且高度耐受有机溶剂的劣化，液体流动性能优异，具有高的样品加载速率并且允许手性化合物的光学异构体的有效拆分。

3. 发明申请

US20080193962A1 Simple Analysis Method of Drugs 有权
标题翻译：药物简单分析方法
公开(公告)号：US20080193962A1
公开(公告)日：2008-08-14
申请号：US11886223
申请日：2006-03-14
申请人： Hiroo Wada , Kiyokatsu Jinno , Yoshihiro Saito , Youkichi Ohno , Makiko Hayashida
发明人： Hiroo Wada , Kiyokatsu Jinno , Yoshihiro Saito , Youkichi Ohno , Makiko Hayashida
IPC分类号： C12Q1/02
CPC分类号： G01N30/16 , A61K31/465 , G01N30/88 , G01N2030/009 , G01N2030/062 , G01N2030/167 , G01N2030/8813
摘要： The invention provides a method for simple, rapid and inexpensive analysis of drugs such as nicotine and other drugs which are accumulated in biological samples of addictive drugger of tobacco, stimulant drug and the like. The method comprises the steps of introducing the biological sample into an injection needle, inserting the needle into an injector of a chromatograph and injecting a carrier into the needle to conduct chromatography treatment.
摘要翻译：本发明提供了一种方法，用于简单，快速和便宜地分析烟草，兴奋剂等成瘾药物的生物样品中积累的药物如尼古丁和其他药物。该方法包括以下步骤：将生物样品引入注射针，将针插入色谱仪的注射器中，并将载体注入针中进行色谱处理。

4. 发明授权

US09097693B2 Simple analysis method of drugs 有权
标题翻译：药物简单分析方法
公开(公告)号：US09097693B2
公开(公告)日：2015-08-04
申请号：US11886223
申请日：2006-03-14
申请人： Hiroo Wada , Kiyokatsu Jinno , Yoshihiro Saito , Youkichi Ohno , Makiko Hayashida
发明人： Hiroo Wada , Kiyokatsu Jinno , Yoshihiro Saito , Youkichi Ohno , Makiko Hayashida
IPC分类号： C12Q1/02 , G01N30/16 , A61K31/465 , G01N30/88 , G01N30/00 , G01N30/06
CPC分类号： G01N30/16 , A61K31/465 , G01N30/88 , G01N2030/009 , G01N2030/062 , G01N2030/167 , G01N2030/8813
摘要： The invention provides a method for simple, rapid and inexpensive analysis of drugs such as nicotine and other drugs which are accumulated in biological samples of addictive drugger of tobacco, stimulant drug and the like. The method comprises the steps of introducing the biological sample into an injection needle, inserting the needle into an injector of a chromatograph and injecting a carrier into the needle to conduct chromatography treatment.
摘要翻译：本发明提供了一种方法，用于简单，快速和便宜地分析烟草，兴奋剂等成瘾药物的生物样品中积累的药物如尼古丁和其他药物。该方法包括以下步骤：将生物样品引入注射针，将针插入色谱仪的注射器中，并将载体注入针中进行色谱处理。

5. 发明申请

US20060043022A1 Separating agent for solid-phase extraction 有权
标题翻译：固相萃取分离剂
公开(公告)号：US20060043022A1
公开(公告)日：2006-03-02
申请号：US11215024
申请日：2005-08-31
申请人： Hiroo Wada , Kosuke Fukuzawa
发明人： Hiroo Wada , Kosuke Fukuzawa
IPC分类号： B01D15/08
CPC分类号： G01N1/405 , B01J20/26 , B01J20/286 , B01J20/3242 , B01J20/3268 , B01J20/3289 , B01J20/3293 , B01J2220/58 , B01J2220/62
摘要： The present invention relates to a separating agent for solid-phase extraction which comprises core particles of a base material; a hydrophilic polymer layer formed on the surface of the particles; and a hydrophobic polymer layer formed on the surface of the hydrophilic polymer layer. The separating agent can be used in a cartridge or a column for solid-phase extraction and the latter can in turn be used in a variety of methods such as a method for concentrating a subject to be separated; a method for removing impurities; a method for solid-phase extraction of an environmental, medicinal and/or biological samples; and a method for pre-treating a protein component-containing sample.
摘要翻译：本发明涉及用于固相萃取的分离剂，其包括基材的芯颗粒; 形成在颗粒表面上的亲水性聚合物层; 以及形成在亲水性聚合物层的表面上的疏水性聚合物层。分离剂可用于用于固相萃取的筒或柱中，后者又可用于各种方法，例如用于浓缩待分离物体的方法; 去除杂质的方法; 用于固相萃取环境，药用和/或生物样品的方法; 以及用于预处理含有蛋白质成分的样品的方法。

6. 发明授权

US5651229A Structural component 失效
标题翻译：结构部件
公开(公告)号：US5651229A
公开(公告)日：1997-07-29
申请号：US405707
申请日：1995-03-17
申请人： Hiroo Wada , Koichiro Nawa
发明人： Hiroo Wada , Koichiro Nawa
IPC分类号： E04B2/96 , E04C3/04 , E04C3/08 , E04C3/40 , E04B2/88 , E04C3/00
CPC分类号： E04B2/96 , E04C3/08 , E04C2003/0486 , E04C2003/0491 , E04C2003/0495
摘要： A structure component 7 composed of a vertical-load support trussed structure supporting a load in a vertical direction and arranged along a vertical plane and a horizontal-load support trussed structure supporting a load in a horizontal direction and arranged along a horizontal plane is provided between main mullions 4 in a building. Since the structure component 7 supports the vertical load and the horizontal load at the trussed structures 9, 10, a support strength can define responding to the loads so as to support efficiently.
摘要翻译：由垂直方向负载并沿垂直平面布置的垂直负载支撑桁架结构构成的结构部件7和沿着水平方向支撑负载并沿水平面布置的水平负载支撑桁架结构设置在主楼4在建筑物。由于结构部件7支撑垂直载荷和桁架结构9,10处的水平载荷，因此支撑强度能够响应于载荷而定义以有效地支撑。

7. 发明申请

US20080070795A1 LINKER COMPOUND, PROBE, AND PROBE-IMMOBILIZED CARRIER 审中-公开
标题翻译：链接化合物，探针和探针固定载体
公开(公告)号：US20080070795A1
公开(公告)日：2008-03-20
申请号：US11851865
申请日：2007-09-07
申请人： Keisuke Makino , Tsutomu Kodaki , Seiya Watanabe , Seung Pack , Mitsuru Nonogawa , Hiroo Wada , Yasuko Yoshida , Kazunari Yamada
发明人： Keisuke Makino , Tsutomu Kodaki , Seiya Watanabe , Seung Pack , Mitsuru Nonogawa , Hiroo Wada , Yasuko Yoshida , Kazunari Yamada
IPC分类号： C40B30/06 , C07H21/04 , C40B40/08
CPC分类号： C07D498/04 , C07H19/24 , C07H21/04
摘要： The present invention aims to provide a technique for stably immobilizing a probe on a carrier The present invention provides a linker compound represented by formula (1): wherein A represents a hydrogen atom, another substituent, a sugar, or a derivative thereof.
摘要翻译：本发明的目的在于提供一种用于将探针稳定地固定在载体上的技术。本发明提供由式（1）表示的连接剂化合物：其中A表示氢原子，另一取代基，糖或其衍生物。

8. 发明申请

US20050058774A1 Method for coating solid substrate surface with fine particles 审中-公开
标题翻译：用细颗粒涂布固体基材表面的方法
公开(公告)号：US20050058774A1
公开(公告)日：2005-03-17
申请号：US10937860
申请日：2004-09-10
申请人： Hiroo Wada
发明人： Hiroo Wada
IPC分类号： C09D1/00 , B01L3/00 , C03C17/00 , C08F8/42 , C08J7/06 , C09D5/00 , B05D1/12
CPC分类号： B82Y30/00 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01L3/5027 , C03C17/006 , C03C2217/42 , C08F8/42 , C08J7/06
摘要： A method for coating the surface of a solid material with fine particles of a metal or a metal compound is provided. The method comprises the step of bringing a solid material into close contact with fine particles of a metal or a metal compound to which a compound having at least two mercapto groups is bonded, under light-shielding conditions or under the irradiation with light rays other than laser light rays. The method does not require the use of any specially designed device. It permits the immobilization of fine particles on the surface of a solid within an appropriate period of time, the immobilization thereof even in the environment in which any light cannot be used, the production of a desired fine particle-coated solid material at a low cost and the uniform coating of even a solid material having a wide area with fine particles. Accordingly, the method can be applied to the immobilization of metal fine particles on various solid substrates, for instance, the surface-modification of a support for chromatography, a sensor, an inner wall of glass capillaries, a microchip device, a microarray or a DNA chip.
摘要翻译：提供了用金属或金属化合物的细颗粒涂覆固体材料的表面的方法。该方法包括使固体材料与金属或金属化合物的细颗粒紧密接触的金属或金属化合物，其中具有至少两个巯基的化合物在遮光条件下或在除了激光光线。该方法不需要使用任何专门设计的设备。它允许在合适的时间内固定细小颗粒在固体表面，甚至在不能使用任何光的环境中固定，以低成本生产所需的细颗粒涂覆固体材料甚至具有广泛面积的具有细颗粒的固体材料的均匀涂布。因此，该方法可以应用于金属微粒在各种固体基质上的固定化，例如用于色谱用载体的表面改性，传感器，玻璃毛细管的内壁，微芯片装置，微阵列或 DNA芯片

9. 发明授权

US06780314B2 Separation column for chromatography, medium for solid phase extraction and sample injection system for chromatography 有权
标题翻译：色谱分离柱，固相萃取介质和色谱法样品注入系统
公开(公告)号：US06780314B2
公开(公告)日：2004-08-24
申请号：US09984714
申请日：2001-10-31
申请人： Kiyokatsu Jinno , Yoshihiro Saito , Tsutomu Takeichi , Hiroo Wada
发明人： Kiyokatsu Jinno , Yoshihiro Saito , Tsutomu Takeichi , Hiroo Wada
IPC分类号： B01D1508
CPC分类号： B01J20/28023 , B01J20/28014 , B01J2220/52 , B01J2220/58 , B01J2220/84 , G01N30/6065 , G01N2030/009 , G01N2030/085
摘要： A separation column for chromatography or a medium for solid phase extraction, which comprises a hollow capillary and a collected body packed in the hollow capillary and serving as a stationary phase, the collected body comprising long fibers having an adsorbing ability selective towards a target solute and arranged in the axial direction of the capillary, and a sample injection system which comprises the foregoing hollow capillary incorporated into a loop of a valve or a passage connecting two valves, the valve(s) being used as an injector for the chromatography. The use of the polymeric long fibers, which have chemical structures specially designed so that they can specifically interact with a target substance (a solute or an analyte) to be analyzed, permits the selective or preferential extraction and/or concentration of the solute.
摘要翻译：用于色谱法或固相萃取介质的分离柱，其包含中空毛细管和填充在中空毛细管中并用作固定相的收集体，所述收集体包含对目标溶质具有选择性的吸附能力的长纤维，以及布置在毛细管的轴向上的样品注射系统，以及包含上述中空毛细管的样品注射系统，其结合到阀的环中或连接两个阀的通道，所述阀用作色谱的注射器。使用具有专门设计使得它们可以与待分析的目标物质（溶质或分析物）特异性相互作用的化学结构的聚合长纤维允许选择性或优先提取和/或浓缩溶质。

10. 发明申请

US20120034566A1 MICRO-CHANNEL DEVICE AND METHOD FOR FABRICATING MICRO-CHANNEL DEVICE 审中-公开
标题翻译：用于制造微通道器件的微通道器件和方法
公开(公告)号：US20120034566A1
公开(公告)日：2012-02-09
申请号：US13259840
申请日：2010-03-29
申请人： Hiroo Wada , Hiroshi Tamura , Hiroshi Kobayashi , Tomofumi Kiyomoto , Seokhyoung Hong
发明人： Hiroo Wada , Hiroshi Tamura , Hiroshi Kobayashi , Tomofumi Kiyomoto , Seokhyoung Hong
IPC分类号： B01L3/00 , B23P17/04 , G01N30/00 , G03F7/20
CPC分类号： G01N30/6095 , B01J19/0093 , B01J2219/00826 , B01J2219/00828 , B01J2219/00833 , B01J2219/0086 , B01J2219/00984 , B01L3/502746 , B01L2300/0816 , B01L2300/0883 , B01L2400/0487 , G01N27/44704 , G01N27/44791 , G01N30/6086 , Y10T29/49
摘要： A micro-channel device provided in a solution analysis system using pressure liquid feed comprises a plurality of straight-line channels and curved channels connecting the ends of the neighboring straight-line channels. The width w of each curved channel is smaller than the width t of each straight-line channel. The radius of curvature r of each curved channel is set so that the value of a expressed by formula (1) is equal to or smaller than the value of a at a local maximum point of the theoretical step height H expressed by formula (2) and based on the shape of the curved channel. a=w/r (1) H = u c  w 2 64  γ   D m × a 2  ( a + 2 ) a + 1 ( 2 ) Where, w is a width of the curved channel, uc is a channel passing speed of a solution in the curved channel, γ is a molecular diffusion inhibition factor by basic members present in the curved channel, and Dm is a molecular diffusion coefficient of the solution.
摘要翻译：设置在使用压力液体进料的溶液分析系统中的微通道装置包括多个直线通道和连接相邻直线通道的端部的弯曲通道。每个弯曲通道的宽度w小于每个直线通道的宽度t。每个弯曲通道的曲率半径r被设定为使由公式（1）表示的a的值等于或小于由公式（2）表示的理论台阶高度H的局部最大点处的a值，并基于弯曲通道的形状。 a = w / r（1）H = uc w w 2 64γD m×a 2（a + 2）a + 1（2）其中，w是弯曲通道的宽度，uc是弯曲通道中溶液的通道通过速度，γ是弯曲通道中存在的碱性成分的分子扩散抑制因子，Dm是溶液的分子扩散系数。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式