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1. 发明授权

US06582654B1 Fluid spray system for cleaning and sterilizing medical devices supported on a rack 有权
标题翻译：流体喷雾系统，用于清洁和消毒支架在机架上的医疗设备
公开(公告)号：US06582654B1
公开(公告)日：2003-06-24
申请号：US09498869
申请日：2000-02-07
申请人： Jude A. Kral , Robert M. Priest , Daniel N. Kelsch , James C. Hlebovy , Bill R. Sanford , Alan J. Greszler , Francis John Zelina , Kenneth J. Klobusnik
发明人： Jude A. Kral , Robert M. Priest , Daniel N. Kelsch , James C. Hlebovy , Bill R. Sanford , Alan J. Greszler , Francis John Zelina , Kenneth J. Klobusnik
IPC分类号： A61L218
CPC分类号： A61L2/186 , A61B1/123 , A61B1/125 , A61L2/22 , A61L2/24 , A61L2202/17 , A61L2202/24
摘要： A fluid delivery system (20) for an automated processor (A) includes spray nozzles (102, 104, 106, 108, 110) for sequentially spraying washing, microbial decontaminant and rinsing solutions over a lumened device (B), such as an endoscope. The fluid delivery system also includes connection ports (150, 152, 154) for connecting with internal passages (187) of the device to deliver the washing and microbial decontaminant solutions thereto. A removable rack (21), specially configured for the particular device, positions the device within a chamber (12). The spray nozzles are located on rear and side walls (114, 116, 118) and on a door (18) of the chamber, such that the device is impinged with spray from all directions. Sets (102, 104) of the spray nozzles are pulsed in sequence so that the spray jets (122) do not cancel each other out. Leaking connectors (184) connect the automated processor connection ports with inlet ports (196) of the device and allow a portion of the cleaning, decontaminant, and rinsing solutions to leak from each inlet port. A computer control system (80) controls cleaning, decontamination, rinsing, and drying stages of a cycle, which are all carried out within the chamber, obviating the need for human contact with the device during processing.
摘要翻译：用于自动处理器（A）的流体输送系统（20）包括用于在诸如内窥镜的流明装置（B）上顺序地喷射洗涤，微生物净化剂和冲洗溶液的喷嘴（102,104,106,108,110）。流体输送系统还包括用于与装置的内部通道（187）连接以将洗涤和微生物净化剂溶液输送到其的连接端口（150,152,154）。专门为特定装置配置的可拆装架（21）将装置定位在室（12）内。喷嘴位于后壁和侧壁（114,116,118）上并且位于室的门（18）上，使得该装置从所有方向撞击喷雾。喷雾喷嘴的组（102,104）依次脉冲，使得喷射喷嘴（122）不彼此抵消。泄漏连接器（184）将自动化处理器连接端口与设备的入口端口（196）连接，并允许一部分清洁，去污剂和冲洗溶液从每个入口端口泄漏。计算机控制系统（80）控制循环的清洁，净化，漂洗和干燥阶段，这些阶段都在室内进行，从而避免了在处理过程中与人体接触的需要。

2. 发明授权

US06585943B1 Liquid cleaning and sterilization system 有权
标题翻译：液体清洗灭菌系统
公开(公告)号：US06585943B1
公开(公告)日：2003-07-01
申请号：US09498811
申请日：2000-02-07
申请人： Bill R. Sanford , Jude A. Kral , Joseph Tvergyak , Bernard J. Moss , Robert M. Priest , James C. Hlebovy , Daniel N. Kelsch , Alan J. Greszler , David E. Minerovic , John C. Houston , Nancy A. Robinson
发明人： Bill R. Sanford , Jude A. Kral , Joseph Tvergyak , Bernard J. Moss , Robert M. Priest , James C. Hlebovy , Daniel N. Kelsch , Alan J. Greszler , David E. Minerovic , John C. Houston , Nancy A. Robinson
IPC分类号： E06B1100
CPC分类号： A61L2/186 , A61B1/123 , A61B1/125 , A61L2/22 , A61L2/24 , A61L2202/17 , A61L2202/24 , Y10T292/0993 , Y10T292/1046
摘要： A fluid delivery system (26) for an automated processor (A) delivers washing, microbial decontaminant, and rinse fluids to spray nozzles (102, 104, 106, 108, 110) in a chamber (12) for sequentially spraying the fluids over a lumened device (B), such as an endoscope. The fluid delivery system also delivers the fluids to connection ports (150, 152, 154) which connect with internal passages (187) of the device for delivering the fluids thereto. Leaking connectors (184) connect the automated processor connection ports with inlet ports (196) of the device and allow a portion of the washing, decontaminant, and rinsing solutions to leak from each inlet port. A computer control system (80) controls cleaning, decontamination, rinsing, and drying stages of a cycle, which are all carried out within the chamber, obviating the need for human contact with the device during processing. A door locking and latching mechanism (90) ensures that the door remains locked during the washing, decontamination, and rinse cycle to avoid accidental injury to an operator from strong chemicals used in the system.
摘要翻译：用于自动处理器（A）的流体输送系统（26）将洗涤，微生物净化剂和冲洗流体输送到在腔室（12）中的喷嘴（102,104,106,108,110），以将流体顺序地喷射在一个流明装置（B），诸如内窥镜。流体输送系统还将流体输送到与装置的内部通道（187）连接的连接端口（150,152,154），以将流体输送到其上。泄漏连接器（184）将自动处理器连接端口与设备的入口端口（196）连接，并允许一部分洗涤，去污剂和冲洗溶液从每个入口端口泄漏。计算机控制系统（80）控制循环的清洁，净化，漂洗和干燥阶段，这些阶段都在室内进行，从而避免了在处理过程中与人体接触的需要。门锁和闩锁机构（90）确保在洗涤，去污和漂洗周期期间门保持锁定，以避免操作者因系统中使用的强烈化学物质而造成意外伤害。

3. 发明授权

US06558620B1 Liquid cleaning and sterilization method 有权
标题翻译：液体清洗灭菌方法
公开(公告)号：US06558620B1
公开(公告)日：2003-05-06
申请号：US09499561
申请日：2000-02-07
申请人： Bill R. Sanford , Jude A. Kral , Joseph Tvergyak , Bernard J. Moss , Robert M. Priest , James C. Hlebovy , Daniel N. Kelsch , Alan J. Greszler , David E. Minerovic , John C. Houston , Nancy A. Robinson
发明人： Bill R. Sanford , Jude A. Kral , Joseph Tvergyak , Bernard J. Moss , Robert M. Priest , James C. Hlebovy , Daniel N. Kelsch , Alan J. Greszler , David E. Minerovic , John C. Houston , Nancy A. Robinson
IPC分类号： A61L200
CPC分类号： A61L2/22 , A61B1/123 , A61B1/125 , A61L2/186 , A61L2/24 , A61L2202/14 , A61L2202/17 , A61L2202/21 , A61L2202/24 , Y10S422/905
摘要： A method of washing, microbially decontaminating, and rinsing of a lumened device (B), such as an endoscope includes positioning the device in a chamber (12) of an automated processor (A). Spray nozzles (102, 104, 106, 108, 110) within the chamber sequentially spray washing, microbial decontaminant, and rinse fluids over the device. Fluid connection ports (150, 152, 154) connect with internal passages (187) of the device for delivering the fluids thereto. Leaking connectors (184) connect the automated processor connection ports with inlet ports (196) of the device and allow a portion of the washing, decontaminant, and rinse solutions to leak from each inlet port. A computer control system (80) controls leak testing, cleaning, decontamination, rinsing, and drying stages of a cycle, which are all carried out within the chamber, obviating the need for human contact with the device during processing. A door locking and latching mechanism (90) ensures that the door remains locked during the washing, decontamination, and rinse cycle to avoid accidental injury to an operator from strong chemicals used in the system.
摘要翻译：对诸如内窥镜的流明装置（B）的洗涤，微生物净化和漂洗的方法包括将装置定位在自动处理器（A）的腔室（12）中。腔室内的喷嘴（102,104,106,108,110）依次喷射洗涤剂，微生物净化剂和冲洗流体。流体连接端口（150,152,154）与用于将流体输送的装置的内部通道（187）连接。泄漏连接器（184）将自动处理器连接端口与设备的入口端口（196）连接，并允许一部分洗涤，去污剂和冲洗溶液从每个入口端口泄漏。计算机控制系统（80）控制循环的泄漏测试，清洁，去污，漂洗和干燥阶段，这些阶段都在室内进行，从而避免了在处理过程中与人体接触的需要。门锁和闩锁机构（90）确保在洗涤，去污和漂洗周期期间门保持锁定，以避免操作者因系统中使用的强烈化学物质而造成意外伤害。

4. 发明授权

US06767569B1 Surface decontamination of cooked sausage and processed meat and poultry products 有权
标题翻译：煮熟的香肠和加工的肉类和家禽产品的表面去污
公开(公告)号：US06767569B1
公开(公告)日：2004-07-27
申请号：US09616516
申请日：2000-07-14
申请人： James L. Marsden , Eric W. Krieger , Lewis I. Schwartz , Alan J. Greszler , Bill R. Sanford
发明人： James L. Marsden , Eric W. Krieger , Lewis I. Schwartz , Alan J. Greszler , Bill R. Sanford
IPC分类号： A23B412
CPC分类号： A23L3/3499 , A23B4/033 , A23B4/20 , A23B4/30 , A23L3/349 , A23L3/3508 , A23L3/42 , A23L13/62 , A23L13/65
摘要： Cooked food products, such as cooked meats, and poultry, are treated with a decontaminant solution to remove surface microorganism contamination. The decontaminant solution contains peracetic acid at a concentration of from about 100 to 4000 ppm and has broad spectrum activity against a variety of pathogenic and spoilage microorganisms, such as Listeria monocytogenes.
摘要翻译：煮熟的食物，例如熟肉和家禽，用去污剂溶液处理以除去表面微生物污染物。净化剂溶液含有浓度为约100至4000ppm的过乙酸，并且对各种致病和腐败微生物如单核细胞增生利斯特氏菌具有广谱活性。

5. 发明授权

US06827766B2 Decontaminating systems containing reactive nanoparticles and biocides 有权
公开(公告)号：US06827766B2
公开(公告)日：2004-12-07
申请号：US10267986
申请日：2002-10-08
申请人： Corrie L. Carnes , Kenneth J. Klabunde , Olga Koper , Lisa S. Martin , Kyle Knappenberger , Paul S. Malchesky , Bill R. Sanford
发明人： Corrie L. Carnes , Kenneth J. Klabunde , Olga Koper , Lisa S. Martin , Kyle Knappenberger , Paul S. Malchesky , Bill R. Sanford
IPC分类号： A62D300
CPC分类号： A62D3/30 , A01N25/04 , A01N25/16 , A01N25/34 , A61L2/16 , A61L2/183 , A61L2/186 , A61L2/202 , A61L2/22 , A61L9/14 , A61L2202/122 , A62D3/36 , A62D2101/02 , A62D2101/04 , B82Y30/00 , C02F1/28 , C02F2305/08 , A01N59/06
摘要： Improved area decontamination products and methods of use thereof are provided which include reactive nanoparticles (e.g., metal oxides, hydroxides and mixtures thereof) with one or more biocides and a liquid carrier for the nanoparticles and biocide(s). The products may be formulated for area decontamination as sprays, fogs, aerosols, pastes, gels, wipes or foams, and the presence of reactive nanoparticles enhances the neutralization of undesirable chemical or biological compounds or agents. The nanoparticles may be from the group consisting of the alkali metal, alkaline earth metal, transition metal, actinide and lanthanide oxides and hydroxides and mixtures thereof. In preferred forms, nanocrystalline oxides and hydroxides of Al, Ca, Ce, Mg, Sr, Sn, Ti and Zn are employed having single crystallite sizes of up to about 20 nm and surface areas of at least about 15 m2/g.

6. 发明授权

US5225160A Medical instrument decontamination and sterilization processor 失效
标题翻译：医疗器械去污杀菌处理器
公开(公告)号：US5225160A
公开(公告)日：1993-07-06
申请号：US741788
申请日：1991-08-06
申请人： Bill R. Sanford , Raymond C. Kralovic
发明人： Bill R. Sanford , Raymond C. Kralovic
IPC分类号： A01N25/34 , A61L2/16 , A61L2/18 , A61L2/20 , A61L2/24 , A61L2/26 , A61L15/44 , A61L15/46 , A61L31/16 , B65D77/22 , B65D81/32
CPC分类号： B65D81/3216 , A01N25/34 , A61L2/16 , A61L2/18 , A61L2/20 , A61L2/24 , A61L2/26 , B65D77/225
摘要： An instrument (28) or other item to be sterilized is supported on a hanger (26) in a decontamination chamber (10). A container such as a sleeve (92), is supported at adjacent ends between supporting rings (90) such that the container surrounds and is displaced from the instrument. A pump (40) recirculates a sterilant or other antimicrobial solution that collects in a lower drain (48) and a reservoir (50) through spray nozzles (70, 96) and connectors (44) which are connected to interior passages of the instrument. In this manner, the internal passages of the instrument are sterilized by the flowing liquid and exterior surfaces are sterilized by sterilant solution mist which condenses on and coats the exterior surface. After the instrument is sterilized, a sterile rinse is sprayed on the instrument and interior of the container. The container and instrument are removed as a unit and the container is closed at its ends to prevent the instrument from becoming microbially contaminated from the ambient air. The instrument may be dried passively by a microbe blocking filter (98) in the container or by using a fan (80) to pump drying air longitudinally through the container.
摘要翻译：待消毒的仪器（28）或其他物品被支撑在净化室（10）中的衣架（26）上。诸如套筒（92）的容器被支撑在支撑环（90）之间的相邻端处，使得容器围绕并从仪器移位。泵（40）通过连接到仪器的内部通道的喷嘴（70,96）和连接器（44）再循环收集在下排水口（48）和贮存器（50）中的灭菌剂或其它抗微生物溶液。以这种方式，仪器的内部通道被流动的液体灭菌，并且外表面通过冷凝在外表面上的灭菌溶液雾灭菌。仪器灭菌后，将无菌冲洗液喷洒在仪器和容器内部。容器和仪器作为一个单元被移除，并且容器在其端部被封闭，以防止仪器从环境空气中被微生物污染。仪器可以通过容器中的微生物阻塞过滤器（98）被动地干燥或者通过使用风扇80将干燥空气纵向地泵送通过容器而被干燥。

7. 发明授权

US07566393B2 Method of sorbing sulfur compounds using nanocrystalline mesoporous metal oxides 有权
标题翻译：使用纳米晶介孔金属氧化物吸附硫化合物的方法
公开(公告)号：US07566393B2
公开(公告)日：2009-07-28
申请号：US11114989
申请日：2005-04-26
申请人： Kenneth Klabunde , Bill R. Sanford , P. Jeevanandam
发明人： Kenneth Klabunde , Bill R. Sanford , P. Jeevanandam
IPC分类号： C10G25/00 , B01J23/00 , B01J21/00 , B01J20/00 , B01J29/00
CPC分类号： C10G25/003
摘要： Compounds and methods for sorbing organosulfur compounds from fluids are provided. Generally, compounds according to the present invention comprise mesoporous, nanocrystalline metal oxides. Preferred metal oxide compounds either exhibit soft Lewis acid properties or are impregnated with a material exhibiting soft Lewis acid properties. Methods according to the invention comprise contacting a fluid containing organosulfur contaminants with a mesoporous, nanocrystalline metal oxide. In a preferred embodiment, nanocrystalline metal oxide particles are formed into pellets (14) and placed inside a fuel filter housing (12) for removing organosulfur contaminants from a hydrocarbon fuel stream.
摘要翻译：提供了从流体中吸附有机硫化合物的化合物和方法。通常，根据本发明的化合物包含介孔的纳米晶体金属氧化物。优选的金属氧化物化合物表现出柔软的路易斯酸性质，或浸渍有表现出柔软的路易斯酸性质的材料。根据本发明的方法包括使含有有机硫污染物的流体与介孔的纳米晶体金属氧化物接触。在优选实施例中，纳米晶体金属氧化物颗粒形成颗粒（14）并放置在燃料过滤器壳体（12）内，用于从烃燃料流中除去有机硫污染物。

8. 发明授权

US07341977B2 Method of sorbing sulfur compounds using nanocrystalline mesoporous metal oxides 有权
标题翻译：使用纳米晶介孔金属氧化物吸附硫化合物的方法
公开(公告)号：US07341977B2
公开(公告)日：2008-03-11
申请号：US10600309
申请日：2003-06-20
申请人： Kenneth Klabunde , Bill R. Sanford , P. Jeevanandam
发明人： Kenneth Klabunde , Bill R. Sanford , P. Jeevanandam
IPC分类号： B01J23/00 , B01J21/00 , B01J20/00
CPC分类号： C10G25/003
摘要： Compounds and methods for sorbing organosulfur compounds from fluids are provided. Generally, compounds according to the present invention comprise mesoporous, nanocrystalline metal oxides. Preferred metal oxide compounds either exhibit soft Lewis acid properties or are impregnated with a material exhibiting soft Lewis acid properties. Methods according to the invention comprise contacting a fluid containing organosulfur contaminants with a mesoporous, nanocrystalline metal oxide. In a preferred embodiment, nanocrystalline metal oxide particles are formed into pellets (14) and placed inside a fuel filter housing (12) for removing organosulfur contaminants from a hydrocarbon fuel stream.
摘要翻译：提供了从流体中吸附有机硫化合物的化合物和方法。通常，根据本发明的化合物包含介孔的纳米晶体金属氧化物。优选的金属氧化物化合物表现出柔软的路易斯酸性质，或浸渍有表现出柔软的路易斯酸性质的材料。根据本发明的方法包括使含有有机硫污染物的流体与介孔的纳米晶体金属氧化物接触。在优选实施例中，纳米晶体金属氧化物颗粒形成颗粒（14）并放置在燃料过滤器壳体（12）内，用于从烃燃料流中除去有机硫污染物。

9. 发明授权

US5217698A Office size instrument sterilization system 失效
标题翻译：办公大小仪器灭菌系统
公开(公告)号：US5217698A
公开(公告)日：1993-06-08
申请号：US681118
申请日：1991-04-05
申请人： Norman L. Siegel , David E. Minerovic , Raymond C. Kralovic , Bill R. Sanford , Pamela C. Tanner , Donald J. Rebele , Douglas F. Marshall , Samuel M. Fung , John L. Beiswenger
发明人： Norman L. Siegel , David E. Minerovic , Raymond C. Kralovic , Bill R. Sanford , Pamela C. Tanner , Donald J. Rebele , Douglas F. Marshall , Samuel M. Fung , John L. Beiswenger
IPC分类号： A01N25/34 , A61L2/16 , A61L2/18 , A61L2/20 , A61L2/24 , A61L15/44 , A61L15/46 , A61L31/16 , B65D77/22 , B65D81/32
CPC分类号： A61L2/24 , A01N25/34 , A61L15/44 , A61L15/46 , A61L2/16 , A61L2/18 , A61L2/20 , B65D77/225 , B65D81/3216
摘要： The body portion (A) of a small portable sterilizer has a face panel (46) against which a door (B) is selectively closed. The face panel defines an access opening for a sterilization chamber (10) which receives a cassette (C), an access opening for an anti-microbial concentrate chamber (20) which receives a powdered or other sterilant concentrate, and an outlet opening (50) from a microbe filter which filters microbes from incoming rinse water. The face plate and the door define fluid flow channels (48, 52) therebetween for selectively directing sterilant solutions and rinse solutions among the anti-microbial concentrate chamber, the sterilization chamber, and the microbial filter. The cassette is configured to assure that it is inserted into the sterilization chamber with a unique orientation such that its fluid inlet apertures (114) and outlet apertures (124) are at preselected locations. The door includes generally U-shaped projections (116) which abut an outer surface of the cassette in the sterilization chamber partially surrounding the fluid inlet apertures. The U-shaped projections assure that the cassette is seated in the sterilization chamber and provide a well which directs the circulating fluids into the cassette inlet apertures. A pair of gaskets (56, 86) surround the active portion of the face panel. A vacuum pump (90) selectively draws a vacuum in an annular region (88) between the gaskets, which vacuum locks the door against the face plate in a sealed, closed position. To assure a fluid tight seal, the gaskets are O-rings which are pressed by the vacuum into V-shaped grooves (82, 84).
摘要翻译：小便携式消毒器的主体部分（A）具有面板（46），门（B）选择性地关闭。面板限定用于接收盒（C）的消毒室（10）的入口，用于容纳粉状或其它消毒浓缩物的抗微生物浓缩物室（20）的入口和出口（50））从微生物过滤器过滤器，其过滤来自冲洗水的微生物。面板和门在其间限定流体流动通道（48,52），用于在抗微生物浓缩物室，消毒室和微生物过滤器之间选择性地引导消毒剂溶液和漂洗溶液。盒被构造成确保其以独特的取向插入灭菌室，使得其流体入口孔（114）和出口孔（124）处于预选位置。门包括大致U形突起（116），其邻接在部分地围绕流体入口孔的灭菌室中的盒的外表面。 U形突起确保盒被安置在灭菌室中，并提供一个将循环流体引导到盒入口孔中的孔。一对垫圈（56,86）围绕面板的活动部分。真空泵（90）选择性地在垫圈之间的环形区域（88）中抽真空，真空在密封的关闭位置中真空地将门锁定在面板上。为了确保流体密封，垫圈是由真空压入V形槽（82,84）中的O形环。

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