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1. 发明授权

US5709215A R-wave detection method for implantable cardioverter defibrillators 失效
标题翻译：用于植入式心律转复除颤器的R波检测方法
公开(公告)号：US5709215A
公开(公告)日：1998-01-20
申请号：US524391
申请日：1995-09-06
申请人： Joseph S. Perttu , Dennis A. Brumwell , James E. Brewer , Theodore P. Adams
发明人： Joseph S. Perttu , Dennis A. Brumwell , James E. Brewer , Theodore P. Adams
IPC分类号： A61B5/0456 , A61N1/39
CPC分类号： A61B5/0456 , A61B5/7207 , A61N1/3931
摘要： An ICD detection method for sensing the occurrence of an R-wave improves the ability to distinguish R-waves from noise through the use of variable declining sensitivity thresholds. The method includes the consideration of the amplitude of at least the previous most recent R-wave to determine a declining threshold of sensitivity used to recognize a subsequent electrical signal as an R-wave. In the method, the amplitude of the previous R-wave may be classified, based upon amplitude, and based upon the classification, a desirable time constant for the declining threshold of sensitivity is provided as an exponential or reverse exponential decay. Alternatively, a piece wise use of various decay formulas may be combined and used to avoid false recognition of noise as an R-wave.
摘要翻译：用于感测R波的发生的ICD检测方法通过使用可变下降的灵敏度阈值来提高区分R波与噪声的能力。该方法包括考虑至少先前最近的R波的振幅，以确定用于将后续电信号识别为R波的灵敏度下降阈值。在该方法中，先前R波的振幅可以基于振幅进行分类，并且基于分类，灵敏度下降阈值的期望时间常数被提供为指数或反指数衰减。或者，可以组合并且使用各种衰减公式的分段使用来避免作为R波的噪声的错误识别。

2. 再颁专利

USRE38777E1 Dual battery power system for an implantable cardioverter defibrillator with voltage booster 失效
标题翻译：双电池电源系统，用于具有升压器的可植入式心律转复除颤器
公开(公告)号：USRE38777E1
公开(公告)日：2005-08-16
申请号：US08766634
申请日：1996-12-13
申请人： Theodore P. Adams , Dennis A. Brumwell , Joseph S. Perttu , Charles G. Supino
发明人： Theodore P. Adams , Dennis A. Brumwell , Joseph S. Perttu , Charles G. Supino
IPC分类号： A61N1/39
摘要： An improved dual battery power system uses two separate battery power sources for an implantable cardioverter defibrillator, each having optimized characteristics for monitoring functions and for output energy delivery functions, respectively. The monitoring functions are supplied electrical power by a first battery source, such as a conventional pacemaker power source in the form of a lithium iodide battery which is optimized for long life at very low current levels. The output energy delivery functions are supplied by a separate second battery source, such as a pair of lithium vanadium pentoxide batteries, which is optimized for high current drain capability and low self-discharge for long shelf life. The first battery source provides electrical power only to the monitoring functions of the implantable cardioverter defibrillator, and the second battery source provides all of the electrical power for the output energy delivery functions.
摘要翻译：改进的双电池电力系统使用两个单独的电池电源用于可植入式心律转复除颤器，每个除颤器分别具有用于监测功能和输出能量传递功能的优化特性。监测功能由第一电池源提供电力，例如碘化锂电池形式的常规起搏器电源，其以非常低的电流水平被优化用于长寿命。输出能量传递功能由单独的第二电池源提供，例如一对锂五氧化二钒电池，其针对高电流漏极能力和低自放电优化以保持长期保存期限。第一电池源仅向可植入式心律转复除颤器的监视功能提供电力，并且第二电池源为输出能量传递功能提供所有电力。

3. 发明授权

US5372605A Dual battery power system for an implantable cardioverter defibrillator 失效
标题翻译：用于植入式心律转复除颤器的双电池电源系统
公开(公告)号：US5372605A
公开(公告)日：1994-12-13
申请号：US108130
申请日：1993-08-16
申请人： Theodore P. Adams , Dennis A. Brumwell , Joseph S. Perttu , Charles G. Supino
发明人： Theodore P. Adams , Dennis A. Brumwell , Joseph S. Perttu , Charles G. Supino
IPC分类号： A61N1/378 , A61N1/39 , H01M2/10 , H01M6/50 , H01M16/00
CPC分类号： A61N1/3975 , A61N1/3787 , A61N1/3931 , A61N1/3956 , H01M16/00 , H01M2/1066 , H01M6/5016
摘要： An improved dual battery power system uses two separate battery power sources for an implantable cardioverter defibrillator, each having optimized characteristics for monitoring functions and for output energy delivery functions, respectively. The monitoring functions are supplied electrical power by a first battery source, such as a conventional pacemaker power source in the form of a lithium iodide battery which is optimized for long life at very low current levels. The output energy delivery functions are supplied by a separate second battery source, such as a pair of lithium vanadium pentoxide batteries, which is optimized for high current drain capability and low self-discharge for long shelf life. The first battery source provides electrical power only to the monitoring functions of the implantable cardioverter defibrillator, and the second battery source provides all of the electrical power for the output energy delivery functions.
摘要翻译：改进的双电池电力系统使用两个单独的电池电源用于可植入式心律转复除颤器，每个除颤器分别具有用于监测功能和输出能量传递功能的优化特性。监测功能由第一电池源提供电力，例如碘化锂电池形式的常规起搏器电源，其以非常低的电流水平被优化用于长寿命。输出能量传递功能由单独的第二电池源提供，例如一对锂五氧化二钒电池，其针对高电流漏极能力和低自放电优化以保持长期保存期限。第一电池源仅向可植入式心律转复除颤器的监视功能提供电力，并且第二电池源为输出能量传递功能提供所有电力。

4. 发明授权

US5749910A Shield for implantable cardioverter defibrillator 失效
标题翻译：用于植入式心律转复除颤器的护盾
公开(公告)号：US5749910A
公开(公告)日：1998-05-12
申请号：US486759
申请日：1995-06-07
申请人： Dennis A. Brumwell , Joseph S. Perttu , Mark W. Kroll , Randall S. Nelson
发明人： Dennis A. Brumwell , Joseph S. Perttu , Mark W. Kroll , Randall S. Nelson
IPC分类号： A61N1/375 , A61N1/39
CPC分类号： A61N1/3956 , A61N1/375 , A61N1/3758
摘要： An implantable cardioverter defibrillator capable of subcutaneous positioning within a patient delivers at least one electrical cardioversion/defibrillation countershocks to the heart of the patient. The implantable cardioverter defibrillator includes a housing, circuitry positioned within the housing to control delivery of the countershocks, and an energy source coupled with the circuitry to provide electrical energy to a capacitor in the circuitry that stores the electrical energy for delivery of the countershocks. Because the circuitry is susceptible to undesirable electromagnetic coupling effects of origin external to the circuitry, particularly the capacitive coupling effects between the circuitry and the housing of the device when at least a portion of the housing is utilized as an electrode, the implantable cardioverter defibrillator also includes a conductive shield, disposed between the housing and the circuitry, to shield the circuitry against such undesired coupling effects.
摘要翻译：能够在患者体内皮下定位的植入式心律转复除颤器将至少一个电复律/去颤颤颤抗原递送至患者的心脏。植入式心律转复除颤器包括壳体，位于壳体内的电路，用于控制反射的传送，以及与该电路耦合的能量源，以将电能提供给电路中的电容器，该电路存储用于递送该反射的电能。因为当至少一部分壳体被用作电极时，电路容易受到电路外部原点的不期望的电磁耦合影响，特别是电路和器件壳体之间的电容耦合效应，所以可植入的心律转复除颤器也包括设置在外壳和电路之间的导电屏蔽，以屏蔽电路免受这种不期望的耦合影响。

5. 发明授权

US5325870A Multiplexed defibrillation electrode apparatus 失效
标题翻译：多路除颤电极装置
公开(公告)号：US5325870A
公开(公告)日：1994-07-05
申请号：US991132
申请日：1992-12-16
申请人： Mark W. Kroll , Theodore P. Adams , Joseph S. Perttu , Charles Supino
发明人： Mark W. Kroll , Theodore P. Adams , Joseph S. Perttu , Charles Supino
IPC分类号： A61N1/05 , A61N1/39 , A61N1/04
CPC分类号： A61N1/3956 , A61N1/0563
摘要： A defibrillation electrode apparatus which provides defibrillating, pacing, and sensing functions with the use of fewer conductors. Conductor requirements are minimized by solid-state multiplexing that is accomplished at the distal end of the apparatus.
摘要翻译：一种除颤电极装置，其使用更少的导体提供除颤，起搏和感测功能。导体要求通过在设备的远端实现的固态复用来最小化。

6. 发明授权

US5531782A Implantable medical electrode with reduced number of conductors 失效
标题翻译：具有减少导体数量的植入式医用电极
公开(公告)号：US5531782A
公开(公告)日：1996-07-02
申请号：US239778
申请日：1994-05-09
申请人： Mark W. Kroll , Theodore P. Adams , Joseph S. Perttu , Charles Supino
发明人： Mark W. Kroll , Theodore P. Adams , Joseph S. Perttu , Charles Supino
IPC分类号： A61N1/05 , A61N1/39
CPC分类号： A61N1/3956 , A61N1/0563
摘要： A defibrillation electrode apparatus which provides defibrillating, pacing, and sensing functions with the use of fewer conductors. Conductor requirements are minimized by solid-state multiplexing that is accomplished at the distal end of the apparatus. The apparatus comprises:a. a body structure;b. a number "X", wherein X is at least 3, of electrode members disposed on the body structure for electrical communication with the exterior environment;c. a number "X-Y", wherein Y is a number between 1 and X-2, of conductive lead members, each lead member being communicatively connected to at least one electrode member and extending therefrom to a predetermined point on the body structure, and wherein each electrode member is connected to one lead member and at least one lead member is connected to more than one electrode member; andd. a rectifier connected between at least one lead member and at least one electrode member.
摘要翻译：一种除颤电极装置，其使用更少的导体提供除颤，起搏和感测功能。导体要求通过在设备的远端实现的固态复用来最小化。该装置包括：a。身体结构; b。设置在与外部环境电连通的主体结构上的电极构件的数量“X”，其中X为至少3个; C。导电引线构件的数量“XY”，其中Y是1和X-2之间的数字，每个引线构件通信地连接到至少一个电极构件并从其延伸到主体结构上的预定点，并且其中每个电极构件连接到一个引线构件，并且至少一个引线构件连接到多于一个的电极构件; 和d。连接在至少一个引线部件和至少一个电极部件之间的整流器。

7. 发明授权

US5690685A Automatic battery-maintaining implantable cardioverter defibrillator and method for use 失效
标题翻译：自动电池维护植入式心律转复除颤器及其使用方法
公开(公告)号：US5690685A
公开(公告)日：1997-11-25
申请号：US549284
申请日：1995-10-27
申请人： Mark W. Kroll , Joseph S. Perttu
发明人： Mark W. Kroll , Joseph S. Perttu
IPC分类号： A61N1/378 , A61N1/39
CPC分类号： A61N1/3925 , A61N1/378 , A61N1/3931 , A61N1/3975
摘要： A device and method for performing automatic battery maintenance as particularly applied in an implantable cardioverter defibrillator (ICD). The battery is maintained at a predetermined state-of-charge to enable charging a capacitor in the ICD to discharge high voltage pulse into a human patient via electrodes implanted in the patient.
摘要翻译：用于执行自动电池维护的设备和方法，特别适用于可植入式心律转复除颤器（ICD）。将电池保持在预定的充电状态，以使ICD中的电容器能够充电，通过植入患者体内的电极将高电压脉冲放电至人类患者。

8. 发明授权

US6112118A Implantable cardioverter defibrillator with slew rate limiting 失效
标题翻译：具有转换速率限制的植入式心律转复除颤器
公开(公告)号：US6112118A
公开(公告)日：2000-08-29
申请号：US896311
申请日：1997-06-28
申请人： Mark W. Kroll , Joseph S. Perttu
发明人： Mark W. Kroll , Joseph S. Perttu
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/3912 , Y10S128/901
摘要： The present invention is a pectorally implantable defibrillation system for delivering at least one electrical cardioversion/defibrillation countershock. The system has a housing designed to be implanted in a human patient, wherein the housing has an outer shell and an inner cavity. Pulse generating circuitry is positioned within the cavity for generating the at least one countershock. Circuitry is also positioned within the cavity to control delivery of the at least one countershock. A slew rate limiting circuit is connected between the pulse generating circuitry and one of a plurality of implantable electrodes so as to reduce a slew rate of the electrical countershock. Preferably, one of the implantable electrodes is the housing.
摘要翻译：本发明是一种用于输送至少一个电复律/去颤除颤器的胸腔可植入除颤系统。该系统具有设计成植入人类患者的壳体，其中壳体具有外壳和内腔。脉冲发生电路位于空腔内，用于产生至少一个反冲。电路也位于空腔内，以控制至少一个倒伏的输送。压摆率限制电路连接在脉冲发生电路和多个可植入电极中的一个之间，以便降低电气倒伏的转换速率。优选地，可植入电极中的一个是壳体。

9. 发明授权

US5645572A Implantable cardioverter defibrillator with slew rate limiting 失效
标题翻译：具有转换速率限制的植入式心律转复除颤器
公开(公告)号：US5645572A
公开(公告)日：1997-07-08
申请号：US615516
申请日：1996-03-12
申请人： Mark W. Kroll , Joseph S. Perttu
发明人： Mark W. Kroll , Joseph S. Perttu
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/3912 , Y10S128/901
摘要： The present invention is a pectorally implantable defibrillation system for delivering at least one electrical cardioversion/defibrillation countershock. The system has a housing designed to be implanted in a human patient, wherein the housing has an outer shell and an inner cavity. Pulse generating circuitry is positioned within the cavity for generating the at least one countershock. Circuitry is also positioned within the cavity to control delivery of the at least one countershock. At least one surface of the outer shell is electrically conductive to form an electrode for the system. Because of the close proximity between the housing electrode and the circuitry positioned within the housing, the circuitry is susceptible to undesired capacitive coupling effects. To reduce the capacitive coupling effects, a slew rate limiting circuit is connected between the pulse generating circuitry and the electrode formed on the housing.
摘要翻译：本发明是一种用于输送至少一个电复律/去颤除颤的临时植入式除颤系统。该系统具有设计成植入人类患者的壳体，其中壳体具有外壳和内腔。脉冲发生电路位于空腔内，用于产生至少一个反冲。电路也位于空腔内，以控制至少一个倒伏的输送。外壳的至少一个表面是导电的，以形成用于该系统的电极。由于壳体电极和位于壳体内的电路之间的紧密接近，电路易受不期望的电容耦合效应的影响。为了降低电容耦合效应，在脉冲发生电路和形成在壳体上的电极之间连接有转换速率限制电路。

10. 发明授权

US5904705A Automatic battery-maintaining implantable cardioverter defibrillator and method for use 失效
标题翻译：自动电池维护植入式心律转复除颤器及其使用方法
公开(公告)号：US5904705A
公开(公告)日：1999-05-18
申请号：US835556
申请日：1997-04-08
申请人： Mark W. Kroll , Joseph S. Perttu
发明人： Mark W. Kroll , Joseph S. Perttu
IPC分类号： A61N1/378 , A61N1/39
CPC分类号： A61N1/3925 , A61N1/378 , A61N1/3931 , A61N1/3975
摘要： A device and method for performing automatic battery maintenance as particularly applied in an implantable cardioverter defibrillator (ICD). The battery is maintained at a predetermined state-of-charge to enable charging a capacitor in the ICD to discharge high voltage pulse into a human patient via electrodes implanted in the patient.
摘要翻译：用于执行自动电池维护的设备和方法，特别适用于可植入式心律转复除颤器（ICD）。将电池保持在预定的充电状态，以使ICD中的电容器能够充电，通过植入患者体内的电极将高电压脉冲放电至人类患者。

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