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1. 发明申请

US20100137143A1 METHODS AND APPARATUS FOR MEASURING ANALYTES 审中-公开
公开(公告)号：US20100137143A1
公开(公告)日：2010-06-03
申请号：US12474897
申请日：2009-05-29
申请人： Jonathan M. Rothberg , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
发明人： Jonathan M. Rothberg , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
IPC分类号： C40B20/00 , C12Q1/68 , C12P19/34 , C40B40/06 , C40B60/10
CPC分类号： G01N27/4145 , C12Q1/6869 , C12Q1/6874 , G01N27/4148 , H01L21/82 , C12Q2565/607
摘要： Methods and apparatus relating to FET arrays including large FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.

2. 发明申请

US20130217004A1 METHODS AND APPARATUS FOR MEASURING ANALYTES 审中-公开
标题翻译：测量分析仪的方法和装置
公开(公告)号：US20130217004A1
公开(公告)日：2013-08-22
申请号：US13612742
申请日：2012-09-12
申请人： Jonathan M. ROTHBERG , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
发明人： Jonathan M. ROTHBERG , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
IPC分类号： C12Q1/68
CPC分类号： G01N27/4145 , C12Q1/6869 , C12Q1/6874 , G01N27/4148 , H01L21/82 , C12Q2565/607
摘要： Methods and apparatus relating to FET arrays including large FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.
摘要翻译：涉及FET阵列的方法和装置，包括用于监测化学和/或生物反应的大型FET阵列，例如核酸序列合成反应。本文提供的一些方法涉及在核酸测序反应期间从释放的氢离子改进信号（以及信噪比）。

3. 发明申请

US20110281737A1 Method and Apparatus for Rapid Nucleic Acid Sequencing 审中-公开
公开(公告)号：US20110281737A1
公开(公告)日：2011-11-17
申请号：US13027500
申请日：2011-02-15
申请人： Jonathan M. ROTHBERG , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
发明人： Jonathan M. ROTHBERG , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
IPC分类号： C40B20/00
CPC分类号： G01N27/4145 , C12Q1/6869 , C12Q1/6874 , G01N27/4148 , H01L21/82 , C12Q2565/607
摘要： Methods and apparatus relating to FET arrays including large FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.

4. 发明申请

US20110275522A1 Method and Apparatus for Rapid Nucleic Acid Sequencing 审中-公开
公开(公告)号：US20110275522A1
公开(公告)日：2011-11-10
申请号：US13027459
申请日：2011-02-15
申请人： Jonathan M. ROTHBERG , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
发明人： Jonathan M. ROTHBERG , Wolfgang Hinz , John F. Davidson , Antoine M. van Oijen , John H. Leamon , Martin Huber
IPC分类号： C40B20/00 , C12Q1/68
CPC分类号： G01N27/4145 , C12Q1/6869 , C12Q1/6874 , G01N27/4148 , H01L21/82 , C12Q2565/607
摘要： Methods and apparatus relating to FET arrays including large FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.

5. 发明申请

US20160346888A1 Machining Device for Machine-Assisted Production and Machining of Dental Workpieces 审中-公开
标题翻译：机械辅助加工牙科工件加工装置
公开(公告)号：US20160346888A1
公开(公告)日：2016-12-01
申请号：US15113070
申请日：2015-01-21
申请人： Martin Huber , Alfons Wörmer Wörmer
发明人： Martin Huber , Alfons Wörmer Wörmer
IPC分类号： B23Q7/10 , B25J11/00 , A61C13/00 , B23Q7/04
CPC分类号： B23Q7/10 , A61C13/0004 , A61C13/0022 , B23B3/065 , B23Q1/623 , B23Q3/15706 , B23Q3/15713 , B23Q3/15722 , B23Q3/15766 , B23Q7/046 , B23Q7/047 , B23Q11/0891 , B23Q39/024 , B23Q39/042 , B23Q2003/15537 , B23Q2003/155418 , B23Q2003/155428 , B23Q2003/155446 , B25J11/005 , Y10S483/902 , Y10T29/5114 , Y10T29/519 , Y10T483/115 , Y10T483/16 , Y10T483/1705 , Y10T483/1714 , Y10T483/1724 , Y10T483/1755 , Y10T483/1788 , Y10T483/1882
摘要： The invention relates to a machining device for the machine-assisted production and machining of dental workpieces (16), particularly of artificial teeth and/or other dental replacement parts, the at least one workpiece (16) being clamped in at least one work-piece retainer (11) which can be raised, lowered and rotatably driven, is positioned on a rotational axis (9), and, for the purpose of machining, feeds said workpiece (16) to at least one tool spindle (4, 5, 6) that is rotationally driven and has a tool (7) secured thereto, an additional tool retainer (2, 2a, 2b) with a plurality of tools (7) arranged thereupon being associated with said workpiece retainer (11, 11a, 11b) and lying opposite on one side thereof, and a workpiece changer (22, 22a, 22b) which receives the workpieces (16, 16a, 16b, 16c) to be machined, such that they can be exchanged, being arranged on the other side of said workpiece retainer (11, 11a, 11b).
摘要翻译：本发明涉及一种用于机器辅助生产和加工牙科工具（16）的加工装置，特别是人造牙齿和/或其他牙齿更换部件，所述至少一个工件（16）夹紧在至少一个工作部件中，可以升高，降低和可旋转地驱动的片保持器（11）位于旋转轴线（9）上，并且为了加工的目的，将所述工件（16）馈送到至少一个工具主轴（4,5） 6），其被旋转地驱动并具有固定到其上的工具（7），具有与所述工件保持器（11,11a，11b）相关联的多个工具（7）的附加工具保持器（2,2a，2b）并且在其一侧相对地放置，并且接收待加工的工件（16,16a，16b，16c）可以更换的工件更换器（22,22a，22b）布置在所述工件保持器（11,11a，11b）。

6. 发明授权

US09307909B2 Method and system for associating at least two different medical findings with each other 有权
标题翻译：将至少两种不同医学发现相互关联的方法和系统
公开(公告)号：US09307909B2
公开(公告)日：2016-04-12
申请号：US13742842
申请日：2013-01-16
申请人： Andrew John Hewett , Martin Huber , Gerhard Kohl , Markus Metz , Michael Rusitska
发明人： Andrew John Hewett , Martin Huber , Gerhard Kohl , Markus Metz , Michael Rusitska
IPC分类号： G06T7/00 , A61B5/00 , G06F19/00
CPC分类号： A61B5/0033 , A61B5/0035 , A61B5/748 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T2207/30004 , G16H10/60 , G16H15/00
摘要： One embodiment of the invention is disclosed, related to a method for associating at least two different medical findings with each other, each of the findings being based on a characteristic area in a different set of images. The location of at least one anatomical landmark in relation to the respective characteristic area is determined in each in each of the different sets of images. Then a reference to the least one anatomical landmark is stored together with the respective finding for each of the at least two findings. Finally, pairs of associated findings based on a comparison of the respective references to the at least one anatomical landmark are identified among the at least two findings.
摘要翻译：公开了本发明的一个实施例，涉及将至少两个不同医学发现相互关联的方法，每个发现基于不同图像集合中的特征区域。关于各个特征区域的至少一个解剖标记的位置在每个不同图像组中的每一个中被确定。然后将至少一个解剖学标记的引用与至少两个发现中的每一个的相应发现一起存储。最后，在至少两个发现之间确定基于对至少一个解剖学标记的相应参考的比较的相关联发现对。

7. 发明授权

US08280133B2 Method and system for brain tumor segmentation in 3D magnetic resonance images 有权
标题翻译： 3D磁共振图像脑肿瘤分割的方法和系统
公开(公告)号：US08280133B2
公开(公告)日：2012-10-02
申请号：US12506674
申请日：2009-07-21
申请人： Michael Wels , Gustavo Henrique Monteiro de Barros Carneiro , Martin Huber , Dorin Comaniciu
发明人： Michael Wels , Gustavo Henrique Monteiro de Barros Carneiro , Martin Huber , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06K9/469 , G06K9/4614 , G06K9/6257 , G06K9/6297 , G06K2209/05 , G06T7/11 , G06T7/143 , G06T7/162 , G06T2207/10088 , G06T2207/30016
摘要： A method and system for brain tumor segmentation in multi-spectral 3D MRI images is disclosed. A trained probabilistic boosting tree (PBT) classifier is used to determine, for each voxel in a multi-spectral 3D MR image sequence, a probability that the voxel is part of a brain tumor. The brain tumor is then segmented in the multi-spectral 3D MRI image sequence using graph cuts segmentation based on the probabilities determined using the trained PBT classifier and intensities of the voxels in the multi-spectral 3D MR image sequence.
摘要翻译：公开了一种用于多光谱3D MRI图像中脑肿瘤分割的方法和系统。训练后的概率增强树（PBT）分类器用于为多光谱3D MR图像序列中的每个体素确定体素是脑肿瘤一部分的概率。然后使用基于使用经训练的PBT分类器确定的概率和多光谱3D MR图像序列中的体素的强度的图切割分割，在多光谱3D MRI图像序列中将脑肿瘤分割。

8. 发明授权

US08202130B2 Data cable 有权
标题翻译：数据线
公开(公告)号：US08202130B2
公开(公告)日：2012-06-19
申请号：US13057008
申请日：2009-07-02
申请人： Norbert Friese , Martin Huber
发明人： Norbert Friese , Martin Huber
IPC分类号： H01R13/648
CPC分类号： H01R24/40 , H01R13/5045 , H01R13/6592 , H01R2103/00 , Y10T29/49176 , Y10T29/49181
摘要： A data cable including an electrical line with a plurality of line leads, an electrical shield, a molded piece including first counterpart form-locking elements and a housing enclosing the molded piece, wherein the housing has a central opening. The data cable further including a plug connector disposed on an end of the data cable, wherein the plug connector is electrically connected to the shield, wherein the plug connector includes a bush that is enclosed by the molded piece. The bush includes a deep-drawn tube and a bead with second form-locking elements which with the counterpart form-locking elements form a first form-locking connection, wherein an outer contour of the molded piece and an inner contour of the central opening of the housing form a second form-locking connection.
摘要翻译：一种数据电缆，包括具有多条线引线的电线，电屏蔽，包括第一配对形式锁定元件的模制件和封闭模制件的壳体，其中壳体具有中心开口。所述数据电缆还包括设置在所述数据电缆的一端的插头连接器，其中所述插头连接器电连接到所述屏蔽件，其中所述插头连接器包括被所述模制件封闭的衬套。衬套包括深拉管和具有第二形状锁定元件的胎圈，其中对应形式锁定元件形成第一成形锁定连接，其中模制件的外部轮廓和中心开口的内部轮廓壳体形成第二形状锁定连接。

9. 发明授权

US08009343B2 Optical imaging device having at least one system diaphragm 有权
标题翻译：具有至少一个系统隔膜的光学成像装置
公开(公告)号：US08009343B2
公开(公告)日：2011-08-30
申请号：US10566196
申请日：2004-07-02
申请人： Bernhard Gellrich , Thomas Bischoff , Hermann Bieg , Martin Huber , Francois Henzelin , Gerhard Szekely , Uy-Liem Nguyen , Martin E. Humphries
发明人： Bernhard Gellrich , Thomas Bischoff , Hermann Bieg , Martin Huber , Francois Henzelin , Gerhard Szekely , Uy-Liem Nguyen , Martin E. Humphries
IPC分类号： G02B27/72
CPC分类号： G03F7/70091 , G02B5/005 , G03F7/7025
摘要： An optical imaging device (PL), in particular an objective for semiconductor lithography, is provided with at least one system diaphragm. The system diaphragm comprises a multiplicity of mobile plates, which are rotatably mounted. The plates have a spherical curvature.
摘要翻译：具有至少一个系统隔膜的光学成像装置（PL），特别是用于半导体光刻的物镜。系统隔膜包括可旋转地安装的多个移动板。板具有球形曲率。

10. 发明申请

US20100317535A1 Methods and Compositions For Detecting Nucleic Acid Molecules 审中-公开
标题翻译：用于检测核酸分子的方法和组合物
公开(公告)号：US20100317535A1
公开(公告)日：2010-12-16
申请号：US12839100
申请日：2010-07-19
申请人： Wolfgang Schmidt , Axel Mundlein , Martin Huber , Hans Kroath
发明人： Wolfgang Schmidt , Axel Mundlein , Martin Huber , Hans Kroath
IPC分类号： C40B30/00 , C40B40/06
CPC分类号： C12Q1/689 , C12Q1/6813 , C12Q1/6832 , C12Q1/6837 , C12Q2600/16 , C12Q2565/501 , C12Q2527/107
摘要： There is provided methods and compositions for simultaneously detecting at least two mutually different nucleic acid molecules in a sample. In particular, the methods and composition may be employed in the multiplex detection of antibiotic resistance genes in bacteria.
摘要翻译：提供了用于同时检测样品中至少两个相互不同的核酸分子的方法和组合物。特别地，所述方法和组合物可用于细菌中抗生素抗性基因的多重检测。

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