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1. 发明授权

US08529494B2 Methods and apparatus for treating glaucoma 有权
公开(公告)号：US08529494B2
公开(公告)日：2013-09-10
申请号：US13610769
申请日：2012-09-11
申请人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
发明人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
IPC分类号： A61F9/007 , A61M1/00
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/007 , A61F2009/00885 , A61F2009/00891 , A61K9/0051 , A61M27/002 , A61M2210/0612 , Y10S623/905 , Y10S623/906
摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

2. 发明申请

US20130231603A1 Ocular Implants and Methods for Delivering Ocular Implants Into the Eye 有权
标题翻译：眼部植入物和将眼部植入物植入眼睛的方法
公开(公告)号：US20130231603A1
公开(公告)日：2013-09-05
申请号：US13865770
申请日：2013-04-18
申请人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
发明人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
IPC分类号： A61F9/007
CPC分类号： A61F9/0017 , A61F9/0026 , A61F9/00781
摘要： An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.
摘要翻译：提供眼部植入物。在一些实施例中，眼部植入物包括围绕纵向中心轴线弯曲的主体和限定包括通道开口的纵向通道的远侧主体部分。植入物的尺寸和构造使得眼睛植入物呈现出当眼部植入物置于施莱姆氏管中时通道开口邻近施莱姆管道的主侧的取向。还提供了将眼部植入物输送到施莱姆氏管中的方法。一些方法包括覆盖眼部植入物中的开口，将植入物推进到施莱姆氏管中，同时至少一些开口被覆盖，并且在植入物的远端部分设置在施莱姆管中时露出开口。

3. 发明申请

US20130079701A1 Methods and Apparatus for Delivering Ocular Implants Into the Eye 有权
公开(公告)号：US20130079701A1
公开(公告)日：2013-03-28
申请号：US13681365
申请日：2012-11-19
申请人： Andrew T. Schieber , John Wardle , Edward Matthees , Charles L. Euteneuer
发明人： Andrew T. Schieber , John Wardle , Edward Matthees , Charles L. Euteneuer
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61M25/0068 , A61M25/01 , A61M31/00 , A61M2025/0004
摘要： A method of deploying an ocular implant into Schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.

4. 发明申请

US20130006165A1 Methods and Apparatus for Treating Glaucoma 有权
公开(公告)号：US20130006165A1
公开(公告)日：2013-01-03
申请号：US13610769
申请日：2012-09-11
申请人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
发明人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
IPC分类号： A61F9/007 , A61M1/00
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/007 , A61F2009/00885 , A61F2009/00891 , A61K9/0051 , A61M27/002 , A61M2210/0612 , Y10S623/905 , Y10S623/906
摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

5. 发明申请

US20130338563A1 Methods and Apparatus for Delivering Ocular Implants Into the Eye 有权
标题翻译：眼睛植入眼睛的方法和装置
公开(公告)号：US20130338563A1
公开(公告)日：2013-12-19
申请号：US13973864
申请日：2013-08-22
申请人： Andrew T. Schieber , John Wardle , Edward Matthees , Charles L. Euteneuer
发明人： Andrew T. Schieber , John Wardle , Edward Matthees , Charles L. Euteneuer
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61B17/3417 , A61B17/3468 , A61F2/148 , A61F2/15
摘要： A method of deploying an ocular implant into Schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.
摘要翻译：一种将眼部植入物部署到人眼的施莱姆氏管中的方法，包括以下步骤：将眼睛的前房中的输送工具的远端通过眼睛的小梁网插入眼睛的施莱姆氏管中; 并且将眼睛植入物推进通过输送工具的弯曲部分和远端开口，以将眼部植入物的主体部分放置在施莱姆氏管中，并将眼部植入物的入口部分放置在前房中。

6. 发明授权

US08551166B2 Methods and apparatus for delivering ocular implants into the eye 有权
公开(公告)号：US08551166B2
公开(公告)日：2013-10-08
申请号：US13681365
申请日：2012-11-19
申请人： Andrew T. Schieber , John Wardle , Edward Matthees , Charles L. Euteneuer
发明人： Andrew T. Schieber , John Wardle , Edward Matthees , Charles L. Euteneuer
IPC分类号： A61F2/16
CPC分类号： A61F9/00781 , A61M25/0068 , A61M25/01 , A61M31/00 , A61M2025/0004
摘要： A method of deploying an ocular implant into Schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.

7. 发明申请

US20130158462A1 Delivering Ocular Implants Into the Eye 有权
标题翻译：将眼部植入眼睛
公开(公告)号：US20130158462A1
公开(公告)日：2013-06-20
申请号：US13330592
申请日：2011-12-19
申请人： John Wardle , Andrew T. Schieber
发明人： John Wardle , Andrew T. Schieber
IPC分类号： A61F9/007
CPC分类号： A61F9/0026 , A61B17/3421 , A61B17/3468 , A61B2017/3454 , A61F9/0017 , A61F9/00781 , A61F2220/0033
摘要： A method of deploying an ocular implant into Schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with Schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening. The invention also includes a system for practicing the method.
摘要翻译：将眼部植入物部署到施莱姆的眼睛的运河中的方法。该方法包括以下步骤：将套管的远端插入眼睛的角膜并插入眼睛的前房，该套管具有从远端延伸并穿过侧壁的远端开口; 放置套管的远端开口与施莱姆氏管流体连通; 通过具有与眼部植入物接合的输送工具将眼部植入物向远端推进通过套管，眼睛植入物的近端部分接近输送工具的远端部分; 并且当眼部植入物的近端部分到达套管远端开口时，使眼部植入物和递送工具脱离接合。本发明还包括实施该方法的系统。

8. 发明授权

US08425449B2 Ocular implants and methods for delivering ocular implants into the eye 有权
公开(公告)号：US08425449B2
公开(公告)日：2013-04-23
申请号：US12833863
申请日：2010-07-09
申请人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
发明人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
IPC分类号： A61M5/00
CPC分类号： A61F9/0017 , A61F9/0026 , A61F9/00781
摘要： An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.

9. 发明申请

US20110098809A1 Ocular Implant System and Method 审中-公开
标题翻译：眼植入系统和方法
公开(公告)号：US20110098809A1
公开(公告)日：2011-04-28
申请号：US12911451
申请日：2010-10-25
申请人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
发明人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
IPC分类号： A61F2/16
CPC分类号： A61F9/00781
摘要： An ocular implant and delivery system having a channel tool adapted to extend through at least a portion of Schlemm's canal of a human eye and to determine whether the Schlemm's canal portion provides a suitable location for the delivery of an ocular implant; an ocular implant adapted to be disposed within Schlemm's canal of a human eye; and a cannula comprising a distal opening adapted to deliver the channel tool and the ocular implant into Schlemm's canal of the eye. The invention also provides a method of treating glaucoma in a human eye including the steps of inserting a distal exit port of a cannula at least partially into Schlemm's canal of the eye; delivering a channel tool through the cannula into Schlemm's canal; delivering an ocular implant through the cannula into Schlemm's canal; and removing the channel tool and the cannula from the eye while leaving the ocular implant in place within Schlemm's canal.
摘要翻译：一种眼部植入物和递送系统，其具有适于延伸穿过人眼的施莱姆氏管的至少一部分的通道工具，并且确定施莱姆氏管部分是否提供用于输送眼部植入物的合适位置; 一种眼部植入物，适于放置在人眼的施莱姆氏管内; 以及套管，其包括适于将所述通道工具和所述眼部植入物输送到所述眼睛的施莱姆氏管中的远侧开口。本发明还提供了一种治疗人眼中的青光眼的方法，包括将套管的远侧出口至少部分地插入眼睛的施莱姆氏管中的步骤; 将通道工具通过套管输送到施莱姆的运河中; 通过插管将眼部植入物递送到施莱姆氏管中; 并从眼睛上移除通道工具和套管，同时将眼部植入物留在施莱姆氏管内。

10. 发明申请

US20130281907A1 Ocular Implants for Delivery into an Anterior Chamber of the Eye 有权
标题翻译：用于输送到眼睛前房的眼部植入物
公开(公告)号：US20130281907A1
公开(公告)日：2013-10-24
申请号：US13793638
申请日：2013-03-11
申请人： John Wardle , Andrew T. Schieber
发明人： John Wardle , Andrew T. Schieber
IPC分类号： A61F9/007
CPC分类号： A61F9/00781
摘要： An ocular implant adapted to be disposed within Schlemm's canal of a human eye with a body extending along a curved longitudinal central axis in a curvature plane, a first strut on one side of the implant and a second strut on an opposite side of the implant, the circumferential extent of the first strut with respect to the plane of curvature being greater than the circumferential extent of the second strut with respect to the plane of curvature. The invention also includes methods of using the implant.
摘要翻译：一种眼部植入物，其适于设置在人眼的施莱姆氏管内，其主体沿着曲率平面中的弯曲纵向中心轴线延伸，植入物一侧上的第一支柱和植入物相对侧上的第二支柱，第一支柱相对于曲面平面的圆周范围大于第二支柱相对于曲面平面的圆周范围。本发明还包括使用植入物的方法。

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