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1. 发明授权

US07517043B2 Fluidic structures 有权
标题翻译：流体结构
公开(公告)号：US07517043B2
公开(公告)日：2009-04-14
申请号：US11014356
申请日：2004-12-16
申请人： John S. Fitch , Scott Elrod , Jurgen Daniel , James W. Stasiak , Steven A. Buhler , Babur B. Hadimioglu , Joy Roy , Michael C. Weisberg , James C. Zesch
发明人： John S. Fitch , Scott Elrod , Jurgen Daniel , James W. Stasiak , Steven A. Buhler , Babur B. Hadimioglu , Joy Roy , Michael C. Weisberg , James C. Zesch
IPC分类号： B41J2/015
CPC分类号： B01L3/0268 , B01L2200/12 , B01L2300/0819 , B01L2400/0433 , B01L2400/0605 , B01L2400/084
摘要： Various fluidic techniques can employ ducting structures, such as microstructures, that extend between other components, such as plate-like structures. A ducting structure can, for example, include an inlet opening toward or near one plate-like structure, an outlet opening toward or near another plate-like structure, and a duct in which fluid flows after being received through the inlet opening and before being provided through the outlet opening. In some implementations, a ducting structure is photo-defined, such as by exposing a photoimageable structure and then removing either exposed or unexposed regions. In some implementations, a ducting structure is a freestanding polymer microstructure. In some implementations, ducting structures are microstructures that extend approximately the same length between first and second plate-like structures, and have a ratio of length to maximum cavity diameter of approximately two or more. A printhead implementation includes an array of such microstructures supported between drive side and drop side assemblies.
摘要翻译：各种流体技术可以采用在诸如板状结构的其他部件之间延伸的管道结构，例如微结构。管道结构可以例如包括朝向或靠近一个板状结构的入口开口，朝向或接近另一个板状结构的出口，以及在通过入口开口之后流体流动的管道通过出口开口提供。在一些实施方案中，管道结构是光限定的，例如通过曝光可光成像的结构，然后去除暴露或未曝光的区域。在一些实施方案中，管道结构是独立的聚合物微结构。在一些实施方案中，管道结构是在第一和第二板状结构之间延伸大致相同长度的微结构，并且具有大约两个或更多个长度与最大腔直径的比率。打印头实现包括支撑在驱动侧和液滴侧组件之间的这种微结构的阵列。

2. 发明授权

US06447086B1 Method and apparatus for achieving controlled RF switching ratios to maintain thermal uniformity in the acoustic focal spot of an acoustic ink printhead 有权
标题翻译：用于实现受控的RF切换比以保持声学墨水打印头的声学焦点中的热均匀性的方法和装置
公开(公告)号：US06447086B1
公开(公告)日：2002-09-10
申请号：US09449038
申请日：1999-11-24
申请人： Lamar T. Baker , Steven A. Buhler , Scott Elrod , William F. Gunning , Babur B. Hadimioglu , Abdul M. El Hatem , Joy Roy , Richard Stearns
发明人： Lamar T. Baker , Steven A. Buhler , Scott Elrod , William F. Gunning , Babur B. Hadimioglu , Abdul M. El Hatem , Joy Roy , Richard Stearns
IPC分类号： B41J2938
CPC分类号： B41J2/14008
摘要： A number of architectures of switch compensation networks are described for the provision of a compensation current which ensures the maintaining of a desired switching ratio in an acoustic printhead. The described architectures include those which provide column compensation, row compensation, and row and column compensation to a transducer switching matrix. Control of the switching ratio by the compensation networks, is used in consideration of the dissipation of heat energy through expulsion of a heated drop, to provide a precisely controlled balance.
摘要翻译：描述了开关补偿网络的许多架构，用于提供补偿电流，其确保在声学打印头中保持期望的开关比。所描述的架构包括向传感器开关矩阵提供列补偿，行补偿以及行和列补偿的结构。通过补偿网络控制切换比，考虑到通过排出加热液滴的热能耗散，以提供精确控制的平衡。

3. 发明授权

US06283580B1 Method of operation of an acoustic ink jet droplet emitter utilizing high liquid flow rates 有权
标题翻译：使用高液体流速的声学喷墨液滴发射器的操作方法
公开(公告)号：US06283580B1
公开(公告)日：2001-09-04
申请号：US09359520
申请日：1999-07-23
申请人： Joy Roy , Michael C. Weisberg , Jerry Elkin , Babur B. Hadimioglu
发明人： Joy Roy , Michael C. Weisberg , Jerry Elkin , Babur B. Hadimioglu
IPC分类号： B41S2135
CPC分类号： B41J2/14008 , B41J2202/08
摘要： A method of operation of an acoustic droplet emitter with an array of droplet emitting utilizing high liquid flow rates. The higher flow rates prevent excess heat absorption during the droplet emission process and allow for excess heat generated by control electronics to be transferred to the flowing liquid after droplet emission but before it leaves the droplet emitter. This prevents excess heat build-up within the droplet emitter and allows for higher more accurate droplet emission.
摘要翻译：一种使用高液体流速的具有液滴发射阵列的声液滴发射器的操作方法。较高的流速可以防止在液滴喷射过程中过多的吸热，并且允许控制电子产生的多余的热量在液滴发射之后但在其离开液滴发射器之前转移到流动的液体。这可以防止液滴发射器内的过多的热量积聚，并允许更高精度的液滴发射。

4. 发明授权

US06199970B1 Acoustic ink jet printhead design and method of operation utilizing ink cross-flow 有权
标题翻译：声喷墨打印头的设计和操作方法利用油墨交叉流动
公开(公告)号：US06199970B1
公开(公告)日：2001-03-13
申请号：US09361035
申请日：1999-07-23
申请人： Joy Roy , Michael C. Weisberg , Jerry Elkin , Babur B. Hadimioglu
发明人： Joy Roy , Michael C. Weisberg , Jerry Elkin , Babur B. Hadimioglu
IPC分类号： B41J2135
CPC分类号： B41J2/14008 , B41J2202/08
摘要： A droplet emitter with an array of droplet emitting devices constructed such that a flowing liquid used create the droplets can flow through the droplet emitter at higher flow rates. The higher flow rates prevent excess heat absorption during the droplet emission process and allow for excess heat generated by control electronics to be transferred to the flowing liquid after droplet emission but before it leaves the droplet emitter. This prevents excess heat build-up within the droplet emitter and allows for higher more accurate droplet emission.
摘要翻译：具有液滴发射器件阵列的液滴发射器被构造成使得所使用的流动液体产生液滴可以以更高的流速流过液滴发射器。较高的流速可以防止在液滴喷射过程中过多的吸热，并且允许控制电子产生的多余的热量在液滴发射之后但在其离开液滴发射器之前转移到流动的液体。这可以防止液滴发射器内的过多的热量积聚，并允许更高精度的液滴发射。

5. 发明授权

US06713022B1 Devices for biofluid drop ejection 有权
标题翻译：生物流体液滴喷射装置
公开(公告)号：US06713022B1
公开(公告)日：2004-03-30
申请号：US09724987
申请日：2000-11-22
申请人： Jaan Noolandi , David A. Horine , Babur B. Hadimioglu , Richard H. Bruce , Joy Roy , Scott A. Elrod
发明人： Jaan Noolandi , David A. Horine , Babur B. Hadimioglu , Richard H. Bruce , Joy Roy , Scott A. Elrod
IPC分类号： B41J2175
CPC分类号： B01L3/0268 , B01L2400/0439 , G01N35/1002 , G01N2035/102 , G01N2035/1041
摘要： A biofluid drop ejection unit for ejecting biofluid drops. A biofluid drop ejection mechanism of such a unit includes a transducer, which generates energy used to emit the biofluid drop. Further provided is a reagent cartridge or biofluid containment area which holds the biofluid. The reagent cartridge or biofluid containment area is configured to hold low volumes of biofluid and to avoid contamination of the biofluid. The reagent cartridge or biofluid containment area is in operational connection with the drop ejection mechanism such that upon operation of the drop ejection mechanism, biofluid drops are emitted. The biofluid drop ejection mechanism is a high efficiency device, and may be configured as two separate pieces or as a single disposable unit.
摘要翻译：用于喷射生物流体滴的生物流体滴落喷射单元。这种单元的生物流体液滴喷射机构包括换能器，其产生用于发射生物流体滴的能量。另外还提供了一个保持生物流体的试剂盒或生物流体容纳区域。试剂盒或生物流体容纳区域被配置为保持低体积的生物流体并避免污染生物流体。试剂盒或生物流体容纳区域与液滴喷射机构操作连接，使得在液滴喷射机构的操作时，发射生物流体液滴。生物流体液滴喷射机构是高效率的装置，并且可以被配置为两个分开的部件或者作为单个一次性部件。

6. 发明授权

US6134291A Acoustic ink jet printhead design and method of operation utilizing flowing coolant and an emission fluid 有权
标题翻译：声喷墨打印头设计和使用流动的冷却剂和排放流体的操作方法
公开(公告)号：US6134291A
公开(公告)日：2000-10-17
申请号：US361038
申请日：1999-07-23
申请人： Joy Roy , Babur B. Hadimioglu
发明人： Joy Roy , Babur B. Hadimioglu
IPC分类号： B41J2/14 , B41J2/135
CPC分类号： B41J2/14 , B41J2/14008
摘要： A droplet emitter with an array of droplet emitting devices constructed such that one flowing liquid is used to create the droplets while a second low acoustic impedance liquid can be used to both make the transfer of acoustic energy to the first liquid more efficient and help maintain a uniform temperature of the droplet emitter array. Both the emission fluid and the low acoustic impedance fluid can be circulated through the droplet emitter to allow for excess heat generated by control electronics to be transferred to the flowing. This prevents for instance excess heat build up within the droplet emitter and allows for higher more accurate droplet emission.
摘要翻译：具有液滴发射装置的阵列的液滴发射器被构造成使得一个流动的液体被用于产生液滴，而第二低声阻抗液体可以用于使声能量转移到第一液体更有效并且有助于维持液滴发射器阵列的均匀温度。排放流体和低声阻抗流体都可以通过液滴发射器循环，从而允许由控制电子器件产生的多余的热量传递给流动。这防止了例如在液滴发射器内积聚多余的热量并允许更高精度的液滴发射。

7. 发明授权

US06861034B1 Priming mechanisms for drop ejection devices 有权
标题翻译：液滴喷射装置的启动机构
公开(公告)号：US06861034B1
公开(公告)日：2005-03-01
申请号：US09721388
申请日：2000-11-22
申请人： Scott A. Elrod , Joy Roy , Babur B. Hadimioglu , Richard H. Bruce , Jaan Noolandi , David A. Horine
发明人： Scott A. Elrod , Joy Roy , Babur B. Hadimioglu , Richard H. Bruce , Jaan Noolandi , David A. Horine
IPC分类号： C12M1/00 , B01L3/02 , B05B1/04 , B05B17/06 , B01L3/00 , B41J23/00 , B41J29/38
CPC分类号： B05B17/0607 , B01L3/0268
摘要： Provided is a priming mechanism for priming a biofluid drop ejection device having a drop ejection opening leading to an ejection reservoir. The priming mechanism includes a vacuum unit which generates a vacuum force, connected to a vacuum nozzle. The vacuum nozzle is located over the drop ejection opening. A disposable sleeve or tubing is attached to the vacuum nozzle and is placed in operational contact with the drop ejection opening. A fluid height detection sensor is positioned to sense a fluid height within at least one of the disposable tubing and the vacuum nozzle. Upon sensing a predetermined fluid height, by the fluid height detection sensor, the priming operation is completed, and the primer mechanism is removed from the operational contact with the drop ejection opening.
摘要翻译：提供了一种用于起动生物流体液滴喷射装置的起动机构，其具有通向喷射储存器的液滴喷射开口。起动机构包括产生与真空喷嘴连接的真空力的真空单元。真空喷嘴位于液滴喷射口的上方。一次性套筒或管道连接到真空喷嘴并且与液滴喷射口处于操作接触。液体高度检测传感器被定位成感测至少一个一次性管道和真空喷嘴中的流体高度。通过流体高度检测传感器感测到预定的流体高度时，完成起动操作，并且将底漆机构从与液滴喷射口的操作接触部分移开。

8. 发明授权

US06514704B2 Quality control mechanism and process for a biofluid multi-ejector system 失效
公开(公告)号：US06514704B2
公开(公告)日：2003-02-04
申请号：US09773804
申请日：2001-02-01
申请人： Richard H. Bruce , Scott A. Elrod , Babur B. Hadimioglu , David A. Horine , Jaan Noolandi , Joy Roy , Robert A. Sprague
发明人： Richard H. Bruce , Scott A. Elrod , Babur B. Hadimioglu , David A. Horine , Jaan Noolandi , Joy Roy , Robert A. Sprague
IPC分类号： C12Q168
CPC分类号： G01N35/10 , G01N35/00712 , G01N35/1009 , G01N2035/1037 , G06F19/00
摘要： A method and mechanism for ensuring quality control in printed biological assays is provided. A multi-ejector system having a plurality of individual drop ejectors is loaded with a variety of biofluids. Biofluids include at least a carrier fluid, a biological material to be used in the testing, and markers, such as fluorescent dyes. Data regarding the biofluid loaded in each of the drop ejectors is stored along with an expected signature output of the biofluid. Particularly, the signature output represents signals from individual ones of the fluorescent markers included within the biofluid. Once a biological assay consisting of the biofluid drops has been printed, a scanner capable of detecting the markers scans the biological assay and obtains signature output signals for each of the drops of the biological assay. A comparing operation is undertaken to compare the obtained signature output through the scanning operation, with the expected signature output signals for the biofluid loaded in the corresponding drop ejector. The biological material itself may also be tagged with a marker to ensure its inclusion in the biofluid. By the comparing operation, it is possible to verify the biofluids were loaded in the proper drop ejector, including the proper biological material, and that the drop ejectors are functioning properly.

9. 发明授权

US6154236A Acoustic ink jet printhead design and method of operation utilizing flowing coolant and an emission fluid 有权
标题翻译：声喷墨打印头设计和使用流动的冷却剂和排放流体的操作方法
公开(公告)号：US6154236A
公开(公告)日：2000-11-28
申请号：US361039
申请日：1999-07-23
申请人： Joy Roy , Babur B. Hadimioglu
发明人： Joy Roy , Babur B. Hadimioglu
IPC分类号： B41J2/14 , B41J2/135 , B41J2/05
CPC分类号： B41J2/14008 , B41J2/14
摘要： A droplet emitter with an array of droplet emitting devices constructed such that one flowing liquid is used to create the droplets while a second low acoustic impedance liquid can be used to both make the transfer of acoustic energy to the first liquid more efficient and help maintain a uniform temperature of the droplet emitter array. Both liquids can be circulated through the droplet emitter to allow for excess heat generated by control electronics to be transferred to the flowing liquids. This prevents, for instance excess heat build-up within the droplet emitter and allows for higher more accurate droplet emission rates.
摘要翻译：具有液滴发射装置的阵列的液滴发射器被构造成使得一个流动的液体被用于产生液滴，而第二低声阻抗液体可以用于使声能量转移到第一液体更有效并且有助于维持液滴发射器阵列的均匀温度。这两种液体都可以通过液滴发射器循环，以使控制电子产生的多余的热量转移到流动的液体中。这防止了例如液滴发射器内的过多的热积聚并且允许更高精度的液滴排放速率。

10. 发明申请

US20060132531A1 Fluidic structures 有权
公开(公告)号：US20060132531A1
公开(公告)日：2006-06-22
申请号：US11014356
申请日：2004-12-16
申请人： John Fitch , Scott Elrod , Jurgen Daniel , James Stasiak , Steven Buhler , Babur Hadimioglu , Joy Roy , Michael Weisberg , James Zesch
发明人： John Fitch , Scott Elrod , Jurgen Daniel , James Stasiak , Steven Buhler , Babur Hadimioglu , Joy Roy , Michael Weisberg , James Zesch
IPC分类号： B01L3/00
CPC分类号： B01L3/0268 , B01L2200/12 , B01L2300/0819 , B01L2400/0433 , B01L2400/0605 , B01L2400/084
摘要： Various fluidic techniques can employ ducting structures, such as microstructures, that extend between other components, such as plate-like structures. A ducting structure can, for example, include an inlet opening toward or near one plate-like structure, an outlet opening toward or near another plate-like structure, and a duct in which fluid flows after being received through the inlet opening and before being provided through the outlet opening. In some implementations, a ducting structure is photo-defined, such as by exposing a photoimageable structure and then removing either exposed or unexposed regions. In some implementations, a ducting structure is a freestanding polymer microstructure. In some implementations, ducting structures are microstructures that extend approximately the same length between first and second plate-like structures, and have a ratio of length to maximum cavity diameter of approximately two or more. A printhead implementation includes an array of such microstructures supported between drive side and drop side assemblies.

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