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1. 发明授权

US08263331B2 Device and method for the detection of an analyte 有权
标题翻译：用于检测分析物的装置和方法
公开(公告)号：US08263331B2
公开(公告)日：2012-09-11
申请号：US11655943
申请日：2007-01-22
申请人： Joachim Bangert , Ludwig Bär , Thomas Ehben , Hans-Dieter Feucht , Christian Zilch
发明人： Joachim Bangert , Ludwig Bär , Thomas Ehben , Hans-Dieter Feucht , Christian Zilch
IPC分类号： C12Q1/68 , C12M1/00
CPC分类号： G01N33/54333 , B82Y15/00 , B82Y25/00 , H01F1/0054
摘要： A device and a method are disclosed for the detection and/or for the quantification of an analyte. In at least one embodiment, the device includes a basic matrix and magnetized nanoparticles, which are arranged in moveable fashion in or at the basic matrix and to which catcher molecules that bind specifically to the analyte are anchored. Further, the mobility of the nanoparticle in the basic matrix can be influenced by a binding of the analyte to be detected to the catcher molecules and can be read out magnetically.
摘要翻译：公开了用于检测和/或定量分析物的装置和方法。在至少一个实施方案中，该装置包括基本基质和磁化纳米颗粒，其以可移动的方式设置在碱性基质中或基本基质上，并且特异性结合分析物的捕获剂分子被锚固。此外，纳米颗粒在碱性基质中的迁移率可能受待检测的分析物与捕获剂分子的结合的影响，并且可以磁性地读出。

2. 发明申请

US20070190640A1 Device and method for the detection of an analyte 有权
标题翻译：用于检测分析物的装置和方法
公开(公告)号：US20070190640A1
公开(公告)日：2007-08-16
申请号：US11655943
申请日：2007-01-22
申请人： Joachim Bangert , Ludwig Bar , Thomas Ehben , Hans-Dieter Feucht , Christian Zilch
发明人： Joachim Bangert , Ludwig Bar , Thomas Ehben , Hans-Dieter Feucht , Christian Zilch
IPC分类号： C12M3/00
CPC分类号： G01N33/54333 , B82Y15/00 , B82Y25/00 , H01F1/0054
摘要： A device and a method are disclosed for the detection and/or for the quantification of an analyte. In at least one embodiment, the device includes a basic matrix and magnetized nanoparticles, which are arranged in moveable fashion in or at the basic matrix and to which catcher molecules that bind specifically to the analyte are anchored. Further, the mobility of the nanoparticle in the basic matrix can be influenced by a binding of the analyte to be detected to the catcher molecules and can be read out magnetically.
摘要翻译：公开了用于检测和/或定量分析物的装置和方法。在至少一个实施方案中，该装置包括基本基质和磁化纳米颗粒，其以可移动的方式设置在碱性基质中或基本基质上，并且特异性结合分析物的捕获剂分子被锚固。此外，纳米颗粒在碱性基质中的迁移率可能受待检测的分析物与捕获剂分子的结合的影响，并且可以磁性地读出。

3. 发明申请

US20140110349A1 ASSEMBLY AND METHOD FOR FILTRATION 审中-公开
标题翻译：装配和过滤方法
公开(公告)号：US20140110349A1
公开(公告)日：2014-04-24
申请号：US14118728
申请日：2012-04-13
申请人： Joachim Bangert , Katja Friedrich , Walter Gumbrecht , Karsten Hiltawsky , Peter Paulicka , Manfred Stanzel
发明人： Joachim Bangert , Katja Friedrich , Walter Gumbrecht , Karsten Hiltawsky , Peter Paulicka , Manfred Stanzel
IPC分类号： A61M1/34 , B01D61/18 , B01D61/22
CPC分类号： A61M1/34 , A61M1/3403 , B01D61/18 , B01D61/22 , B01D67/0032 , B01D71/50 , B01D2311/14 , G01N33/491 , G01N2001/4088
摘要： An assembly and a method for filtration are disclosured, which are suitable in particular for the filtration of cells, for example tumor cells, from a sample, for example a blood sample. In the method, a pressure differential between the pressure upstream and the pressure downstream of a filter is determined; and the pressure differential between upstream and downstream of the filter is adjusted such that the pressure differential does not exceed a predetermined value.
摘要翻译：公开了组合物和过滤方法，其特别适用于从样品例如血液样品过滤细胞，例如肿瘤细胞。在该方法中，确定过滤器下游压力和压力之间的压力差; 并且调节过滤器的上游和下游之间的压力差，使得压差不超过预定值。

4. 发明授权

US07933144B2 Component with a logic circuit arrangement with configurable functionality 有权
标题翻译：具有可配置功能的逻辑电路配置的组件
公开(公告)号：US07933144B2
公开(公告)日：2011-04-26
申请号：US10552657
申请日：2004-03-24
申请人： Joachim Bangert , Christian Siemers
发明人： Joachim Bangert , Christian Siemers
IPC分类号： G11C11/00
CPC分类号： H03K17/80 , H03K17/223
摘要： A component with a logic circuit arrangement with configurable functionality, includes several data lines (7), whereby at least a part of the data lines (7) is provided with at least one element (1) which may be switched between two states with different discrete resistances. The data line (7) is opened or closed by the element (1), depending on the switched state.
摘要翻译：具有具有可配置功能的逻辑电路布置的部件包括若干数据线（7），由此至少一部分数据线（7）设置有至少一个元件（1），其可以在具有不同的两个状态之间切换离散电阻。根据切换状态，数据线（7）由元件（1）打开或关闭。

5. 发明授权

US07400166B2 Digital logic unit reconfigurable in nonvolatile fashion 有权
标题翻译：数字逻辑单元可以非易失性方式重新配置
公开(公告)号：US07400166B2
公开(公告)日：2008-07-15
申请号：US11795316
申请日：2005-12-21
申请人： Joachim Bangert
发明人： Joachim Bangert
IPC分类号： G06F7/38 , H03K19/173
CPC分类号： G11C11/16 , H03K19/1735 , H03K19/18
摘要： A circuit analyzes the configured status of cells with a magnetic layer system, resistance of which may be altered by magnetic field pulses, forming a first line branch with data cells arranged in series and a second line branch with configurable cells arranged in series. The circuit includes a difference amplifier for determining a voltage signal giving the difference voltage of the line branches. Also included in the circuit is a voltage shifter for shifting the voltage signal to a value other than 0 volts, such as an adder or subtractor. In addition, the circuit includes a comparator or window comparator, for the decision as to whether the voltage signal lies in a valid or forbidden range and an evaluation unit for evaluating a valid voltage signal and for output of a logical low or high signal.
摘要翻译：电路利用磁层系统分析电池的配置状态，其电阻可以通过磁场脉冲改变，形成具有串联排列的数据单元的第一行分支和具有串联布置的可配置单元的第二行分支。电路包括用于确定给出线路分支的差分电压的电压信号的差分放大器。还包括在电路中的是用于将电压信号转换成0伏以外的值的电压移位器，例如加法器或减法器。此外，电路包括比较器或窗口比较器，用于判断电压信号是否在有效或禁止的范围内，以及用于评估有效电压信号和用于输出逻辑低或高信号的评估单元。

6. 发明申请

US20080143382A1 Programming Matrix 失效
标题翻译：编程矩阵
公开(公告)号：US20080143382A1
公开(公告)日：2008-06-19
申请号：US10592783
申请日：2005-03-10
申请人： Joachim Bangert
发明人： Joachim Bangert
IPC分类号： H03K19/177
CPC分类号： H03K19/17736 , G11C17/02 , H03K19/1778 , H03K19/18
摘要： The invention relates to a programming matrix for the switching of one of n logical inputs to one of j outputs, whereby the programming matrix comprises a slot system with magnetic elements in selected positions, the magnetic and/or electrical properties of which can change or be changed.
摘要翻译：本发明涉及用于将n个逻辑输入中的一个切换到j个输出之一的编程矩阵，由此编程矩阵包括具有选定位置的磁性元素的时隙系统，其磁性和/或电性质可以改变或成为改变了

7. 发明授权

US09091688B2 Method and apparatus for the detection of magnetizable particles 有权
标题翻译：用于检测可磁化颗粒的方法和装置
公开(公告)号：US09091688B2
公开(公告)日：2015-07-28
申请号：US11783020
申请日：2007-04-05
申请人： Joachim Bangert
发明人： Joachim Bangert
IPC分类号： G01N27/87 , G01N33/543
CPC分类号： G01N33/54326 , G01N33/54353
摘要： A method is disclosed for the detection of magnetic particles, so-called beads, immobilized on an essentially flat-planar holding area of a substrate. In at least one embodiment, a sensor array, which is arranged in the holding area and is composed of XMR sensors, is subjected to an external magnetic field and the change in the resistance of an XMR sensor caused by a stray field of a bead is measured to detect the bead, with the external field being produced by passing a direct current through a conductor track which is arranged on the holding area.
摘要翻译：公开了用于检测固定在基板的基本上平坦的保持区域上的磁性颗粒（即所谓的珠子）的方法。在至少一个实施例中，布置在保持区域中并由XMR传感器组成的传感器阵列经受外部磁场，并且由磁珠的杂散场引起的XMR传感器的电阻的变化是被测量以检测珠，其中通过使直流电流通过布置在保持区域上的导体轨道而产生外部场。

8. 发明授权

US07649770B2 Programming matrix 失效
标题翻译：编程矩阵
公开(公告)号：US07649770B2
公开(公告)日：2010-01-19
申请号：US10592783
申请日：2005-03-10
申请人： Joachim Bangert
发明人： Joachim Bangert
IPC分类号： G11C11/15 , G11C11/00 , H01L25/00
CPC分类号： H03K19/17736 , G11C17/02 , H03K19/1778 , H03K19/18
摘要： A programming matrix switches of one of n logical inputs to one of j outputs. The programming matrix includes at least one layer system with multiple magnetic elements situated at selected locations, in which case, during and/or after the formation of the layer system, in the case of at least one of the elements, the magnetic and/or electrical properties thereof can be altered or are altered by means of intervention at least one layer of the element.
摘要翻译：编程矩阵将n个逻辑输入之一切换到j个输出之一。编程矩阵包括至少一个层系统，其中多个磁性元件位于所选择的位置，在这种情况下，在层系统形成期间和/或之后，在至少一个元件的情况下，磁和/或其电性能可通过介入至少一层元件而改变或改变。

9. 发明授权

US07355439B2 Configurable logic circuit arrangement 有权
标题翻译：可配置逻辑电路布置
公开(公告)号：US07355439B2
公开(公告)日：2008-04-08
申请号：US10571790
申请日：2004-10-07
申请人： Joachim Bangert , Christian Siemers
发明人： Joachim Bangert , Christian Siemers
IPC分类号： H03K19/173 , G06F7/38
CPC分类号： H03K19/1737 , H04J3/04
摘要： A configurable logic circuit arrangement includes at least one multiplexer for switching logic signals. The multiplexer includes one or more data inputs and one or more control signal inputs. The at least one multiplexer (8, 12, 13) can be configured by one or more external control signal transmitter elements of the circuit arrangement during the operation of the circuit in a run-time variable manner by configuration signals that are applied to the control inputs and forwards the logical signals that are applied to the data inputs during operation of the circuit in a run-time variable manner.
摘要翻译：可配置逻辑电路装置包括用于切换逻辑信号的至少一个多路复用器。多路复用器包括一个或多个数据输入和一个或多个控制信号输入。所述至少一个多路复用器（8,12,13）可以由电路装置的一个或多个外部控制信号发射器元件在运行时间可变方式的电路运行期间通过施加到控制器的配置信号来配置在运行时可变的方式输入和转发在电路运行期间应用于数据输入的逻辑信号。

10. 发明申请

US20080014651A1 Method and apparatus for the detection of magnetizable particles 有权
标题翻译：用于检测可磁化颗粒的方法和装置
公开(公告)号：US20080014651A1
公开(公告)日：2008-01-17
申请号：US11783020
申请日：2007-04-05
申请人： Joachim Bangert
发明人： Joachim Bangert
IPC分类号： G01N27/72 , B01J19/08
CPC分类号： G01N33/54326 , G01N33/54353
摘要： A method is disclosed for the detection of magnetic particles, so-called beads, immobilized on an essentially flat-planar holding area of a substrate. In at least one embodiment, a sensor array, which is arranged in the holding area and is composed of XMR sensors, is subjected to an external magnetic field and the change in the resistance of an XMR sensor caused by a stray field of a bead is measured to detect the bead, with the external field being produced by passing a direct current through a conductor track which is arranged on the holding area.
摘要翻译：公开了用于检测固定在基板的基本上平坦的保持区域上的磁性颗粒（即所谓的珠子）的方法。在至少一个实施例中，布置在保持区域中并由XMR传感器组成的传感器阵列经受外部磁场，并且由磁珠的杂散场引起的XMR传感器的电阻的变化是被测量以检测珠，其中通过使直流电流通过布置在保持区域上的导体轨道而产生外部场。

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