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    • 3. 发明申请
    • METHOD AND APPARATUS FOR NOTIFICATION OF EMITTED ENERGY
    • 用于通知发射能量的方法和装置
    • US20120224559A1
    • 2012-09-06
    • US13469512
    • 2012-05-11
    • Xiaotao RenLei WanZhiyu YanYajun ZhaoXiaoan Fan
    • Xiaotao RenLei WanZhiyu YanYajun ZhaoXiaoan Fan
    • H04W72/04H04W52/04
    • H04W52/04H04W52/143H04W52/283
    • The present invention discloses a method and an apparatus for notification of emitted energy. The method includes: performing an emitted energy decrease on resource elements in a current cell that have a same time-frequency location as part or all of resource elements where a reference signal of a neighboring cell is located; obtaining an emitted energy parameter of an energy non-decreased resource element (NRE) in the current cell according to a decreased amount of emitted energy of an emitted energy decreased resource element (DRE); and notifying the emitted energy parameter of the NRE to a user equipment (UE). According to embodiments of the present invention, the waste of emitted energy may be avoided, the emitted energy of part of REs is increased, and further, the signal to interference plus noise ratio (SINR) and throughput of service data may be increased.
    • 本发明公开了一种通知发射能量的方法和装置。 该方法包括:对当前小区中的资源元素执行发射的能量减少,其具有与相邻小区的参考信号所在的资源元素的部分或全部相同的时间 - 频率位置; 根据发射能量减少的资源元素(DRE)的发射能量的减少量,获得当前小区中能量非减少资源元素(NRE)的发射能量参数; 并向用户设备(UE)通知NRE发射的能量参数。 根据本发明的实施例,可以避免发射能量的浪费,部分RE的发射能量增加,此外,信号干扰加噪声比(SINR)和服务数据吞吐量可能会增加。
    • 6. 发明授权
    • Process for the preparation of atorvastatin and intermediates
    • 制备阿托伐他汀和中间体的方法
    • US07812179B2
    • 2010-10-12
    • US12222690
    • 2008-08-14
    • Fan WangDaqing CheBhaskar Reddy GuntooriYajun ZhaoAaron C. KinsmanJody FaughtAlan Chow
    • Fan WangDaqing CheBhaskar Reddy GuntooriYajun ZhaoAaron C. KinsmanJody FaughtAlan Chow
    • C07D207/333
    • C07D207/34
    • A process is provided for preparing (R)-5-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-3-oxo-1-heptanoic acid, R-substituted ester 9 comprising: (a) reacting the aldehyde 1 with the enolate form of (S)-2-hydroxy-1,2,2-triphenylethyl acetate substituent in a chelating co-solvent; (b) hydrolysis of (R,S)-5-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3-hydroxy-1-pentanoic acid, (S)-2-hydroxy-1,2,2-triphenylethyl ester (2a and 2b) using a base, preferably an alkali metal base, preferably in a solvent to form the carboxylic acid 7; (c) treating the acid 7 with a chiral base to form a salt and purifying the salt to obtain enantiomerically enriched (R)-7 chiral base salt; (d) alkylation of the (R)-7 chiral base salt or the free base derived from (R)-7, forming (R)-5-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-3-oxo-1-heptanoic acid, R-substituted ester 9 and atorvastatin calcium 6, wherein R is a C1 to C6 alkyl, C6 to C9 aryl or C7 to C10 aralkyl.
    • 提供了制备(R)-5- [2-(4-氟苯基)-5-(1-甲基乙基)-3-苯基-4 - [(苯基氨基)羰基] -1H-吡咯-1-基] -5-羟基-3-氧代-1-庚酸,R-取代的酯9,其包含:(a)使醛1与烯醇化形式的(S)-2-羟基-1,2,2-三苯基乙基乙酸酯取代基 在螯合助溶剂中; (b)(R,S)-5- [2-(4-氟苯基)-5-(1-甲基乙基)-3-苯基-4 - [(苯基氨基)羰基] -1H-吡咯-1-基 ] -3-羟基-1-戊酸,(S)-2-羟基-1,2,2-三苯基乙酯(2a和2b),使用碱,优选碱金属碱,优选在溶剂中形成羧酸 酸7; (c)用手性碱处理酸7以形成盐并纯化该盐以获得对映体富集的(R)-7手性碱盐; (d)(R)-7手性碱盐或衍生自(R)-7的游离碱的烷基化,形成(R)-5- [2-(4-氟苯基)-5-(1-甲基乙基) 3-苯基-4 - [(苯基氨基)羰基] -1H-吡咯-1-基] -5-羟基-3-氧代-1-庚酸,R-取代的酯9和阿托伐他汀钙6,其中R是C1 C6烷基,C6〜C9芳基或C7〜C10芳烷基。