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1. 发明授权

US5610060A Isolated Helicobacter hepaticus 失效
标题翻译：分离的幽门螺杆菌
公开(公告)号：US5610060A
公开(公告)日：1997-03-11
申请号：US266414
申请日：1994-06-24
申请人： Jerrold M. Ward , James G. Fox , Michael J. Collins, Jr. , Peter L. Gorelick , Raoul E. Benveniste , Joseph G. Tully , Matthew A. Gonda , Bruce J. Paster , Floyd E. Dewhirst, III
发明人： Jerrold M. Ward , James G. Fox , Michael J. Collins, Jr. , Peter L. Gorelick , Raoul E. Benveniste , Joseph G. Tully , Matthew A. Gonda , Bruce J. Paster , Floyd E. Dewhirst, III
IPC分类号： C07K14/205 , C12N1/20
CPC分类号： C07K14/205 , A01K2217/05
摘要： An isolated bacterium of the genus Helicobacter, characterized by the 16S ribosomal RNA encoding nucleotide sequence defined in the Sequence Listing as SEQ ID NO:1 is provided. An isolated nucleic acid having the nucleotide sequence defined in the Sequence Listing as SEQ ID NO:1 is provided. Such a nucleic acid can be used for diagnosis of infection with H. hepaticus. A nucleic acid of the present invention in a vector suitable for expression of the nucleic acid is also provided. The vector can be in a host suitable for expressing the nucleic acid. A purified antigen specific for H. hepaticus is provided. A method of making an animal model for chronic Helicobacter infection is also provided.
摘要翻译：提供幽门螺杆菌属的分离细菌，其特征在于SEQ ID NO：1在序列表中定义的16S核糖体RNA编码核苷酸序列。提供具有SEQ ID NO：1的序列表中定义的核苷酸序列的分离的核酸。这样的核酸可以用于肝炎肝炎感染的诊断。还提供了本发明的核酸在适于表达核酸的载体中。载体可以在适于表达核酸的宿主中。提供了一种针对肝炎特异性的纯化抗原。还提供了制备用于慢性幽门螺杆菌感染的动物模型的方法。

2. 外观设计

USD340837S Combined beverage container and stand therefor 失效
公开(公告)号：USD340837S
公开(公告)日：1993-11-02
申请号：US529271
申请日：1990-05-29
申请人： James G. Fox
设计人： James G. Fox

3. 发明授权

US08330493B2 High utilization universal logic array with variable circuit topology and logistic map circuit to realize a variety of logic gates with constant power signatures 有权
标题翻译：具有可变电路拓扑和逻辑映射电路的高利用率通用逻辑阵列，实现具有恒定功率签名的各种逻辑门
公开(公告)号：US08330493B2
公开(公告)日：2012-12-11
申请号：US12903782
申请日：2010-10-13
申请人： Brent A. Myers , James G. Fox
发明人： Brent A. Myers , James G. Fox
IPC分类号： H01L25/00 , H03K19/00 , H03K19/20
CPC分类号： H03K19/17768 , G06F21/755 , H01L2924/0002 , H03K19/0013 , H03K19/0944 , H03K19/17704 , H03K19/17728 , H03K19/20 , H04L9/001 , H04L9/003 , H04L2209/046 , H04L2209/12 , H01L2924/00
摘要： Disclosed is a novel circuit able to generate any logic combination possible as a function of the input logic signals. The circuit is described as a 2 input logistic map circuit but may be expanded to 3 or more inputs as required. Further disclosed is a universal logic array with variable circuit topology. A metallization layer and/or a via interconnection between cells in the array elements produce a circuit topology that implements a Boolean function and/or chaotic function and/or a logic function. The novel circuit provides a circuit topology for secure applications with no obvious physical correspondence between control signal values and input to output mapping. Further disclosed is a network which has a power signature independent of input signal state and output transition. This provides a very useful circuit to protect data from decryption from power signature analysis in secure applications.
摘要翻译：公开了一种新颖的电路，其能够根据输入逻辑信号产生任何可能的逻辑组合。该电路被描述为2输入逻辑映射电路，但是可以根据需要扩展到3个或更多个输入。进一步公开的是具有可变电路拓扑的通用逻辑阵列。阵列元件中的单元之间的金属化层和/或通孔互连产生实现布尔函数和/或混沌函数和/或逻辑函数的电路拓扑。新颖的电路为安全应用提供电路拓扑，在控制信号值和输出映射之间没有明显的物理对应关系。还公开了具有与输入信号状态和输出转换无关的功率签名的网络。这提供了一个非常有用的电路，用于在安全应用程序中保护数据免受解密功能签名分析。

4. 再颁专利

USRE36388E Sine/cosine generator and method 失效
标题翻译：正弦/余弦发生器和方法
公开(公告)号：USRE36388E
公开(公告)日：1999-11-09
申请号：US400811
申请日：1995-03-08
申请人： James G. Fox , William R. Young , David B. Chester
发明人： James G. Fox , William R. Young , David B. Chester
IPC分类号： G06F1/035 , G06F7/52 , G06F1/02
CPC分类号： G06F7/5338 , G06F1/0353 , G06F1/0356 , G06F2101/04 , G06F7/49994
摘要： A sine/cosine generator with coarse and fine angles having compressed sine and cosine read only memories (ROMS) by use of symmetry of coarse angles about .pi./4 and, optionally, symmetry of fine angles about 0. The output of the ROMs directly feed multiplexers for utilization of the compressed storage. Addressing of complementary coarse angles is with one's complementing of the address and of complementary fine angles is with two's commplementing of the address. Fine sines and cosines are stored in recoded version for direct use in multipliers for computations using the sum of angles formulas.
摘要翻译：具有粗糙和精细角度的正弦/余弦发生器，通过使用大约π/ 4的粗略角度的对称性和可选的约为0的微小角度的对称性，具有压缩的正弦和余弦只读存储器（ROMS）。ROM的输出直接馈送用于压缩存储器的多路复用器。互补粗角度的寻址是用地址的补充，互补精细角度是两个地址的补充。精细的正弦和余弦存储在重新编码的版本中，用于使用角度公式的和进行计算的乘法器。

5. 发明申请

US20110085662A1 HIGH UTILIZATION UNIVERSAL LOGIC ARRAY WITH VARIABLE CIRCUIT TOPOLOGY AND LOGISTIC MAP CIRCUIT TO REALIZE A VARIETY OF LOGIC GATES WITH CONSTANT POWER SIGNATURES 有权
标题翻译：高可用性通用逻辑阵列，具有可变电路拓扑学和物流映射电路，以实现具有恒定功率标志的多种逻辑门
公开(公告)号：US20110085662A1
公开(公告)日：2011-04-14
申请号：US12903782
申请日：2010-10-13
申请人： Brent A. MYERS , James G. Fox
发明人： Brent A. MYERS , James G. Fox
IPC分类号： H04K1/02 , H03K19/00 , H03K19/094
CPC分类号： H03K19/17768 , G06F21/755 , H01L2924/0002 , H03K19/0013 , H03K19/0944 , H03K19/17704 , H03K19/17728 , H03K19/20 , H04L9/001 , H04L9/003 , H04L2209/046 , H04L2209/12 , H01L2924/00
摘要： Disclosed is a novel circuit able to generate any logic combination possible as a function of the input logic signals. The circuit is described as a 2 input logistic map circuit but may be expanded to 3 or more inputs as required. Further disclosed is a universal logic array with variable circuit topology. A metallization layer and/or a via interconnection between cells in the array elements produce a circuit topology that implements a Boolean function and/or chaotic function and/or a logic function. The novel circuit provides a circuit topology for secure applications with no obvious physical correspondence between control signal values and input to output mapping. Further disclosed is a network which has a power signature independent of input signal state and output transition. This provides a very useful circuit to protect data from decryption from power signature analysis in secure applications.
摘要翻译：公开了一种新颖的电路，其能够根据输入逻辑信号产生任何可能的逻辑组合。该电路被描述为2输入逻辑映射电路，但是可以根据需要扩展到3个或更多个输入。进一步公开的是具有可变电路拓扑的通用逻辑阵列。阵列元件中的单元之间的金属化层和/或通孔互连产生实现布尔函数和/或混沌函数和/或逻辑函数的电路拓扑。新颖的电路为安全应用提供电路拓扑，在控制信号值和输出映射之间没有明显的物理对应关系。还公开了具有与输入信号状态和输出转换无关的功率签名的网络。这提供了一个非常有用的电路，用于在安全应用程序中保护数据免受解密功能签名分析。

6. 发明授权

US5276633A Sine/cosine generator and method 失效
标题翻译：正弦/余弦发生器和方法
公开(公告)号：US5276633A
公开(公告)日：1994-01-04
申请号：US930926
申请日：1992-08-14
申请人： James G. Fox , William R. Young , David B. Chester
发明人： James G. Fox , William R. Young , David B. Chester
IPC分类号： G06F1/035 , G06F7/52 , G06F1/02
CPC分类号： G06F7/5338 , G06F1/0353 , G06F1/0356 , G06F2101/04 , G06F7/49994
摘要： A sine/cosine generator with coarse and fine angles having compressed sine and cosine read only memories (ROMS) by use of symmetry of coarse angles about .pi./4 and, optionally, symmetry of fine angles about 0. The output of the ROMs directly feed multiplexers for utilization of the compressed storage. Addressing of complementary coarse angles is with one's complementing of the address and of complementary fine angles is with two's commplementing of the address. Fine sines and cosines are stored in recoded version for direct use in multipliers for computations using the sum of angles formulas.
摘要翻译：具有粗糙和精细角度的正弦/余弦发生器，其具有通过使用约（pi）/ 4的粗略角度的对称性以及可选地为约为0的细角度的对称性而具有压缩的正弦和余弦只读存储器（ROMS）。ROM 直接供应多路复用器以利用压缩存储。互补粗角度的寻址是用地址的补充，互补精细角度是两个地址的补充。精细的正弦和余弦存储在重新编码的版本中，用于使用角度公式的和进行计算的乘法器。

7. 发明授权

US4863735A Biodegradable polymeric drug delivery system with adjuvant activity 失效
标题翻译：具有佐剂活性的可生物降解聚合物药物递送系统
公开(公告)号：US4863735A
公开(公告)日：1989-09-05
申请号：US914380
申请日：1986-10-02
申请人： Joachim B. Kohn , Robert S. Langer , Steven M. Niemi , James G. Fox
发明人： Joachim B. Kohn , Robert S. Langer , Steven M. Niemi , James G. Fox
IPC分类号： A61K9/22 , A61K39/39 , A61K47/48 , C08G69/10
CPC分类号： C08G69/10 , A61K39/39 , A61K47/48192 , A61K2039/55516 , A61K2039/55555 , A61K2039/55566 , Y10S514/885 , Y10S514/953 , Y10S514/963 , Y10S514/964 , Y10S514/965
摘要： An antigen delivery system utilizing a biodegradable polymer with good mechanical properties in combination with a material stimulating the immune system. The material having adjuvant activity may be polymer degradation products or an adjuvant which is contained within or bound to the polymer. In one embodiment, the polymer is formed from tyrosine dipeptides. Poly(CTTH-iminocarbonate) is a preferred tyrosine dipeptide polymer for constructing implantable delivery systems for antigenic material. The polymer is not an adjuvant in itself but degrades into products which stimulate the immune system. The tyrosine dipeptide can also be used as a conventional adjuvant. The advantages of the system are that a polymer can be used to form a biodegradable integral structure which is useful as both an implantable source of an antigen or other biologically active compound and as a control means for the rate of release of the biologically active compound, wherein the result is sustained, relatively constant delivery of antigen with simultaneous stimulation of the immune response.
摘要翻译：使用具有良好机械性能的生物可降解聚合物与刺激免疫系统的材料组合的抗原递送系统。具有佐剂活性的材料可以是聚合物降解产物或包含在聚合物内或与聚合物结合的佐剂。在一个实施方案中，聚合物由酪氨酸二肽形成。聚（CTTH-亚氨基碳酸酯）是用于构建用于抗原材料的可植入递送系统的优选的酪氨酸二肽聚合物。聚合物本身不是佐剂，但会降解成刺激免疫系统的产物。酪氨酸二肽也可以用作常规佐剂。该系统的优点是可以使用聚合物形成可生物降解的整体结构，其可用作抗原的可植入源或其它生物活性化合物，并且作为生物活性化合物的释放速率的对照手段，其中所述结果是持续的，相对恒定的抗原递送，同时刺激免疫应答。

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