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1. 发明授权

US06906157B2 Polymer particle stabilized by dispersant and method of preparation 失效
标题翻译：通过分散剂稳定的聚合物颗粒和制备方法
公开(公告)号：US06906157B2
公开(公告)日：2005-06-14
申请号：US10118725
申请日：2002-04-09
申请人： Jeffrey W. Leon , Jeanne E. Keading , Dennis E. Smith , Trevor J. Wear , Alan R. Pitt , Peter J. Ghyzel
发明人： Jeffrey W. Leon , Jeanne E. Keading , Dennis E. Smith , Trevor J. Wear , Alan R. Pitt , Peter J. Ghyzel
IPC分类号： C08F2/20 , C08F2/24 , C08F220/56 , C08F267/10 , C08F291/14 , G03C1/73
CPC分类号： C08F2/24 , C08F2/20
摘要： A water dispersible polymer particle stabilized by a hydrophobically capped oligomeric acrylamide dispersant or a heterogeneous method for forming polymer particles comprising providing a water immiscible organic phase comprising at least one monomer dispersed in a continuous water phase and a hydrophobically capped oligomeric acrylamide, and polymerizing the organic phase to yield polymer particles stabilized with hydrophobically capped oligomeric acrylamide. Also, a heterogeneous method for forming polymer particles comprising providing a water immiscible organic dispersed in a continuous water phase, polymerizing the organic phase, and adding hydrophobically capped oligomeric acrylamide to yield polymer particles stabilized with hydrophobically capped oligomeric acrylamide.
摘要翻译：通过疏水封端的低聚丙烯酰胺分散剂稳定的水分散性聚合物颗粒或用于形成聚合物颗粒的非均相方法，包括提供包含分散在连续水相中的至少一种单体的水不混溶的有机相和疏水封端的低聚丙烯酰胺，以产生用疏水封端的低聚丙烯酰胺稳定的聚合物颗粒。此外，形成聚合物颗粒的非均相方法包括提供分散在连续水相中的水不混溶的有机相，聚合有机相，并加入疏水封端的低聚丙烯酰胺，以产生用疏水封端的低聚丙烯酰胺稳定的聚合物颗粒。

2. 发明授权

US07390844B2 Polymer particle stabilized by dispersant and method of preparation 有权
标题翻译：通过分散剂稳定的聚合物颗粒和制备方法
公开(公告)号：US07390844B2
公开(公告)日：2008-06-24
申请号：US11080040
申请日：2005-03-15
申请人： Jeffrey W. Leon , Jeanne E. Kaeding , Dennis E. Smith , Trevor J. Wear , Alan R. Pitt , Peter J. Ghyzel
发明人： Jeffrey W. Leon , Jeanne E. Kaeding , Dennis E. Smith , Trevor J. Wear , Alan R. Pitt , Peter J. Ghyzel
IPC分类号： C08J9/00 , C08F2/44 , C08F2/20 , C08F2/24 , C08F220/56
CPC分类号： C08F2/24 , C08F2/20
摘要： The present invention discloses a water dispersible polymer particle stabilized by a hydrophobically capped oligomeric acrylamide dispersant. The present invention also discloses a heterogeneous method for forming polymer particles comprising providing a water immiscible organic phase comprising at least one monomer dispersed in a continuous water phase and a hydrophobically capped oligomeric acrylamide, and polymerizing said organic phase to yield polymer particles stabilized with hydrophobically capped oligomeric acrylamide. Also disclosed in the present invention is a heterogeneous method for forming polymer particles comprising providing a water immiscible organic dispersed in a continuous water phase, polymerizing said organic phase, and adding bydrophobically capped oligomeric acrylamide to yield polymer particles stabilized with hydrophobically capped oligomeric acrylamide.
摘要翻译：本发明公开了一种由疏水封端的低聚丙烯酰胺分散剂稳定的水分散性聚合物颗粒。本发明还公开了一种用于形成聚合物颗粒的非均相方法，其包括提供包含分散在连续水相中的至少一种单体的水不混溶的有机相和疏水封端的低聚丙烯酰胺，并聚合所述有机相以产生用疏水封端稳定的聚合物颗粒低聚丙烯酰胺。本发明还公开了一种用于形成聚合物颗粒的非均相方法，包括提供分散在连续水相中的水不混溶的有机相，使所述有机相聚合，并加入疏水性封端的低聚丙烯酰胺，以产生用疏水封端的低聚丙烯酰胺稳定的聚合物颗粒。

3. 发明授权

US07059714B2 Ink printing method utilizing stabilized polymeric particles 失效
标题翻译：使用稳定的聚合物颗粒的油墨印刷方法
公开(公告)号：US07059714B2
公开(公告)日：2006-06-13
申请号：US10118697
申请日：2002-04-09
申请人： Jeanne E. Kaeding , Jeffrey W. Leon , Christine J. Landry-Coltrain , Alan R. Pitt , Trevor J. Wear , Gregory E. Missell , Dennis E. Smith
发明人： Jeanne E. Kaeding , Jeffrey W. Leon , Christine J. Landry-Coltrain , Alan R. Pitt , Trevor J. Wear , Gregory E. Missell , Dennis E. Smith
IPC分类号： B41J2/01
CPC分类号： B41M5/52 , B41M5/5236 , B41M5/5254 , B41M5/5272 , B41M5/5281
摘要： The present invention discloses an ink printing method including the steps of: a) providing an ink printer that is responsive to digital data signals; b) loading said printer with an image-recording element including a support having thereon at least one image-receiving layer comprising polymeric particles in a polymeric binder, wherein said polymeric particle is stabilized by a hydrophobically capped oligomeric acrylamide dispersant; c) loading said printer with an ink composition; and d) printing on said image-recording element using said ink composition in response to said digital data signals.
摘要翻译：本发明公开了一种墨水打印方法，包括以下步骤：a）提供响应于数字数据信号的墨水打印机; b）使用包括其上具有至少一个包含聚合物粘合剂中的聚合物颗粒的图像接收层的载体的图像记录元件加载所述打印机，其中所述聚合物颗粒通过疏水封端的低聚丙烯酰胺分散剂稳定; c）用油墨组合物装载所述打印机; 以及d）响应于所述数字数据信号，使用所述墨水组合物在所述图像记录元件上进行打印。

4. 发明授权

US06866902B2 Ink recording element containing stabilized polymeric particles 失效
标题翻译：含有稳定的聚合物颗粒的油墨记录元件
公开(公告)号：US06866902B2
公开(公告)日：2005-03-15
申请号：US10118723
申请日：2002-04-09
申请人： Jeanne E. Kaeding , Jeffrey W. Leon , Christine J. Landry-Coltrain , Alan R. Pitt , Trevor J. Wear , Gregory E. Missell , Dennis E. Smth
发明人： Jeanne E. Kaeding , Jeffrey W. Leon , Christine J. Landry-Coltrain , Alan R. Pitt , Trevor J. Wear , Gregory E. Missell , Dennis E. Smth
IPC分类号： B41J2/01 , B41M5/00 , B41M5/50 , B41M5/52 , C08F2/38 , C08F20/54 , B41M5/40
CPC分类号： B41M5/52 , B41M5/506 , B41M5/5218 , B41M5/5227 , B41M5/5254 , Y10T428/24802
摘要： An ink recording element is described comprising a support having thereon at least one image-receiving layer comprising polymeric particles in a polymeric binder, wherein the polymeric particle is stabilized by a hydrophobically-capped oligomeric acrylamide dispersant.
摘要翻译：描述了一种墨水记录元件，其包括其上具有至少一个包含聚合物粘合剂中的聚合物颗粒的图像接收层的载体，其中聚合物颗粒通过疏水封端的低聚丙烯酰胺分散剂来稳定。

5. 发明申请

US20120058050A1 LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES 有权
标题翻译：装载LATEX光学分子成像探针，含有大量的食物转换染色体
公开(公告)号：US20120058050A1
公开(公告)日：2012-03-08
申请号：US13043057
申请日：2011-03-08
申请人： Tao Ji , Hans F. Schmitthenner , Yonghong Yang , John W. Harder , Jeffrey W. Leon , William J. Harrison , Brian J. Kelley , James R. Bennett , David A. Stegman , Ruizheng Wang
发明人： Tao Ji , Hans F. Schmitthenner , Yonghong Yang , John W. Harder , Jeffrey W. Leon , William J. Harrison , Brian J. Kelley , James R. Bennett , David A. Stegman , Ruizheng Wang
IPC分类号： G01N21/75 , A61K49/00 , A61K47/32 , B82Y15/00 , B82Y5/00
CPC分类号： A61K49/0054 , A61K49/0032 , A61K49/0093 , B82Y15/00
摘要： The present invention relates to a loaded particle comprising at least one fluorescent dye, and in particular, a fluorescent dye with a large Stokes shift. The invention further relates to a method for producing an loaded latex particle, loaded with a fluorescent dye having a large stokes shift. In addition, the present invention relates to latex particles loaded with fluorescent dyes that are organic solvent soluble and insoluble in water. In a preferred embodiment, when the dyes are loaded into the water soluble latex particle, an increase is observed in quantum yield of fluorescence as compared to the quantum yield of the dye in aqueous solvent.
摘要翻译：本发明涉及包含至少一种荧光染料的负载颗粒，特别是具有大的斯托克斯位移的荧光染料。本发明还涉及一种负载胶乳粒子的方法，该方法装载有具有较大的斯托克斯位移的荧光染料。此外，本发明涉及装有荧光染料的胶乳颗粒，其是可溶于和不溶于水的有机溶剂。在优选的实施方案中，当将染料加载到水溶性胶乳颗粒中时，与水性溶剂中染料的量子产率相比，观察到荧光量子产率的增加。

6. 发明申请

US20080181965A1 Loaded latex optical molecular imaging probes 审中-公开
标题翻译：加载乳胶光学分子成像探针
公开(公告)号：US20080181965A1
公开(公告)日：2008-07-31
申请号：US11732424
申请日：2007-04-03
申请人： Jeffrey W. Leon , William J. Harrison , Brian J. Kelley , James R. Bennett , David A. Stegman , Ruizheng Wang , John W. Harder
发明人： Jeffrey W. Leon , William J. Harrison , Brian J. Kelley , James R. Bennett , David A. Stegman , Ruizheng Wang , John W. Harder
IPC分类号： A61K9/14 , C08G63/00 , G01N33/68 , G01N33/00 , C12Q1/02
CPC分类号： A61K49/0093 , A61K49/0021 , A61K49/0032 , A61K49/0036 , A61K49/0058 , B82Y5/00 , C08F212/36 , C08F220/26 , C08F220/28 , C08F222/1006 , Y10T436/143333 , C08F212/08
摘要： The present invention relates to a loaded latex particle comprising a latex material made from a mixture represented by formula (X)m-(Y)n-(Z)o-(W)p, wherein Y is at least one monomer with at least two ethylenically unsaturated chemical functionalities; Z is at least one polyethylene glycol macromonomer with an average molecular weight of between 300 and 10,000; W is an ethylenic monomer different from X, Y, or Z; and X is at least one water insoluble, alkoxethyl containing monomer; and m, n, o, and p are the respective weight percentages of each monomer. The particle may be loaded with a fluorescent dye.
摘要翻译：本发明涉及一种负载的胶乳颗粒，其包含由式（X）m-（Y）n-（Z）o-（W）p表示的混合物制成的胶乳材料，其中Y是至少一种具有至少一个两种烯属不饱和化学官能团; Z是至少一种平均分子量在300和10,000之间的聚乙二醇大分子单体; W是不同于X，Y或Z的烯属单体; X为至少一种不溶于水的含烷氧基乙基单体; m，n，o和p分别为各单体的重量百分比。颗粒可以装载荧光染料。

7. 发明授权

US07250245B2 Switchable polymer printing plates with carbon bearing ionic and steric stabilizing groups 失效
标题翻译：具有碳离子和立体稳定基团的可切换聚合物印版
公开(公告)号：US07250245B2
公开(公告)日：2007-07-31
申请号：US10852552
申请日：2004-05-24
申请人： Paul R. West , Jeffrey W. Leon , Nicki R. Miller
发明人： Paul R. West , Jeffrey W. Leon , Nicki R. Miller
IPC分类号： G03F7/004 , G03F7/30
CPC分类号： B41C1/1041
摘要： The present invention provides an imageable member having an imageable layer including a heat-sensitive ionomer characterized by a net positive or negative charge, and a photothermal conversion material. The photothermal conversion material includes carbonaceous particles having thereon both an organic moiety including an ionic substituent having like charge as the ionomer, and a group represented by the formula —X-[NIon]p-Rterminal; wherein X represents an aromatic group or an alkyl group, NIon represents a non-ionic, non-ionizable group, Rterminal represents hydrogen, an aromatic group, an alkoxy group, or an alkyl group, and p is an integer from 1 to about 500. The heat-sensitive ionomer and modified carbonaceous particles can be formulated in water or water-miscible solvents without agglomeration. Imageable members utilizing the modified carbonaceous particles as a photothermal conversion material exhibit acceptable optical density and exposure speed, and imaged members made therefrom exhibit excellent background performance.
摘要翻译：本发明提供了一种可成像的构件，其具有包括以正正电荷或负电荷为特征的热敏离聚物的可成像层和光热转换材料。光热转换材料包括其上具有包括具有类似电荷的离子取代基的有机部分作为离聚物的碳质粒子，以及由式<βin-line-formula description =“In-line Formulas”end =“lead “？” - X- [NIon] ; <？in-line-formula description =“In-line Formulas”end =“tail”？> 其中X表示芳族基团或烷基，NIon表示非离子型，不可离子化的基团，R 3表示氢，芳基，烷氧基或烷基，p表示是1至约500的整数。热敏离聚物和改性碳质颗粒可以配制成水或水混溶性溶剂而不凝聚。利用改性碳质颗粒作为光热转换材料的可成像构件表现出可接受的光密度和曝光速度，并由其制成的成像构件表现出优异的背景性能。

8. 发明授权

US07148280B2 Polymer microspheres containing latent colorants and method of preparation 有权
标题翻译：含有潜着色剂的聚合物微球及其制备方法
公开(公告)号：US07148280B2
公开(公告)日：2006-12-12
申请号：US10876871
申请日：2004-06-25
申请人： Jeffrey W. Leon , Tiecheng A. Qiao , Robert E. Mccovick
发明人： Jeffrey W. Leon , Tiecheng A. Qiao , Robert E. Mccovick
IPC分类号： C08L89/00
CPC分类号： G03C7/3275 , C09B67/0077 , C09B67/0078 , C09B67/0097
摘要： The present invention relates to a polymer microsphere comprising at least one polymer and at least one bound latent colorant, wherein the microsphere is stabilized by at least one stabilizing polymer. The invention also includes a method of preparing polymer microspheres comprising combining latent colorant, ethylenically unsaturated monomer, stabilizing polymer, and an initiator in solvent and initiating polymerization to form a polymeric microsphere stabilized by a stabilizing polymer bound to the surface of the polymeric microsphere.
摘要翻译：本发明涉及包含至少一种聚合物和至少一种结合的潜在着色剂的聚合物微球，其中所述微球由至少一种稳定聚合物稳定。本发明还包括制备聚合物微球的方法，其包括将潜着色剂，烯键式不饱和单体，稳定聚合物和引发剂在溶剂中组合并引发聚合以形成通过与聚合物微球表面结合的稳定化聚合物稳定的聚合物微球。

9. 发明授权

US06815078B2 Substrate for protein microarray containing functionalized polymer 失效
标题翻译：含有官能化聚合物的蛋白质微阵列底物
公开(公告)号：US06815078B2
公开(公告)日：2004-11-09
申请号：US10091644
申请日：2002-03-06
申请人： Tiecheng A. Qiao , Jeffrey W. Leon , Thomas L. Penner , Zhihao Yang
发明人： Tiecheng A. Qiao , Jeffrey W. Leon , Thomas L. Penner , Zhihao Yang
IPC分类号： B32B904
CPC分类号： C07K1/042 , C07B2200/11 , C07K1/047 , C40B40/00 , Y10S435/96 , Y10S436/809 , Y10T428/31768
摘要： A gelatin-based substrate for fabricating protein arrays, the substrate comprising: gelatin having at least one surface; a polymer scaffold affixed to the gelatin surface; wherein the polymer in the scaffold is rich in reactive units capable of immobilizing proteins.
摘要翻译：一种用于制造蛋白质阵列的基于明胶的底物，所述底物包括：具有至少一个表面的明胶;固定到所述明胶表面的聚合物支架;其中所述支架中的聚合物富含能够固定蛋白质的反应单元。

10. 发明授权

US07169543B2 Blocked aliphatic thiol stabilizers for photothermographic materials 失效
标题翻译：用于光热敏成像材料的封闭的脂族硫醇稳定剂
公开(公告)号：US07169543B2
公开(公告)日：2007-01-30
申请号：US11025633
申请日：2004-12-29
申请人： William D. Ramsden , James B. Philip, Jr. , Doreen C. Lynch , Kui Chen-Ho , Stacy M. Ulrich , Kumars Sakizadeh , Jeffrey W. Leon , George J. Burgmaier
发明人： William D. Ramsden , James B. Philip, Jr. , Doreen C. Lynch , Kui Chen-Ho , Stacy M. Ulrich , Kumars Sakizadeh , Jeffrey W. Leon , George J. Burgmaier
IPC分类号： G03C5/16 , G03C1/498 , G03C1/34
CPC分类号： G03C1/49845 , G03C1/46 , G03C1/49809 , G03C5/17 , Y10S430/156 , Y10S430/159 , Y10S430/167
摘要： Photothermographic materials contain one or more blocked aliphatic thiol compounds in an amount of at least 1 mg/m2 as stabilizers. These compounds have a calculated octanol-water partition coefficient (c log P value) of 2.0 or greater, and an N value equal to or greater than 6.5.
摘要翻译：光热成像材料含有至少1mg / m 2的量的一种或多种封端的脂族硫醇化合物作为稳定剂。这些化合物的辛醇 - 水分配系数（c log P值）为2.0以上，N值等于或大于6.5。

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