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1. 发明授权

US06815078B2 Substrate for protein microarray containing functionalized polymer 失效
标题翻译：含有官能化聚合物的蛋白质微阵列底物
公开(公告)号：US06815078B2
公开(公告)日：2004-11-09
申请号：US10091644
申请日：2002-03-06
申请人： Tiecheng A. Qiao , Jeffrey W. Leon , Thomas L. Penner , Zhihao Yang
发明人： Tiecheng A. Qiao , Jeffrey W. Leon , Thomas L. Penner , Zhihao Yang
IPC分类号： B32B904
CPC分类号： C07K1/042 , C07B2200/11 , C07K1/047 , C40B40/00 , Y10S435/96 , Y10S436/809 , Y10T428/31768
摘要： A gelatin-based substrate for fabricating protein arrays, the substrate comprising: gelatin having at least one surface; a polymer scaffold affixed to the gelatin surface; wherein the polymer in the scaffold is rich in reactive units capable of immobilizing proteins.
摘要翻译：一种用于制造蛋白质阵列的基于明胶的底物，所述底物包括：具有至少一个表面的明胶;固定到所述明胶表面的聚合物支架;其中所述支架中的聚合物富含能够固定蛋白质的反应单元。

2. 发明授权

US06797393B2 Method for making biochip substrate 失效
标题翻译：制造生物芯片基板的方法
公开(公告)号：US06797393B2
公开(公告)日：2004-09-28
申请号：US10020747
申请日：2001-11-30
申请人： Tiecheng A. Qiao , Krishnan Chari , Thomas L. Penner , Zhihao Yang
发明人： Tiecheng A. Qiao , Krishnan Chari , Thomas L. Penner , Zhihao Yang
IPC分类号： B32B902
CPC分类号： B82Y30/00 , B01J2219/00274 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/0063 , B01J2219/00637 , B01J2219/00659 , B01J2219/00677 , B01J2219/00725 , C40B40/10 , G01N33/54353 , Y10T428/31504 , Y10T428/31768
摘要： A gelatin-based substrate for fabricating protein arrays, the substrate containing: gelatin and a trifunctional compound A—L—B; wherein A is a functional group capable of interacting with the gelatin; L is a linking group capable of interacting with A and with B; and B is a functional group capable of interacting with a protein capture agent. A may be the same or different from B.
摘要翻译：用于制造蛋白质阵列的明胶基底物，所述基质含有：明胶和三官能化合物A-L-B; 其中A是能够与明胶相互作用的官能团; L是能够与A和B相互作用的连接基团; 并且B是能够与蛋白质捕获剂相互作用的官能团。 A可能与B相同或不同。

3. 发明授权

US06364456B1 Replenishable coating for printhead nozzle plate 失效
标题翻译：打印头喷嘴板可补充涂层
公开(公告)号：US06364456B1
公开(公告)日：2002-04-02
申请号：US09470809
申请日：1999-12-22
申请人： Zhihao Yang , Ravi Sharma , Thomas L. Penner
发明人： Zhihao Yang , Ravi Sharma , Thomas L. Penner
IPC分类号： B41J241
CPC分类号： B82Y30/00 , B41J2/1433 , B41J2/16552
摘要： A nozzle plate for an ink jet printhead, the nozzle plate having the following layers in the order recited: a) a first monomolecular layer of an organic material having first and second functional groups, the first functional group of the first monomolecular layer being bound to the surface of the nozzle plate, and the second functional group of the first monomolecular layer being bound to a second monomolecular layer, and b) the second monomolecular layer of an organic material having first and second functional groups, the first functional group of the second monomolecular layer being bound to the second functional group of the first monomolecular layer, and the second functional group of the second monomolecular layer is an anti-wetting group.
摘要翻译：一种用于喷墨打印头的喷嘴板，喷嘴板具有以下顺序的层：a）具有第一和第二官能团的有机材料的第一单分子层，第一单分子层的第一官能团与喷嘴板的表面和第一单分子层的第二官能团与第二单分子层结合，以及b）具有第一和第二官能团的有机材料的第二单分子层，第二官能团的第二官能团单分子层与第一单分子层的第二官能团结合，第二单分子层的第二官能团为抗潮湿基团。

4. 发明授权

US06325490B1 Nozzle plate with mixed self-assembled monolayer 有权
标题翻译：喷嘴板与混合自组装单层
公开(公告)号：US06325490B1
公开(公告)日：2001-12-04
申请号：US09224533
申请日：1998-12-31
申请人： Zhihao Yang , Thomas L. Penner , Ravi Sharma
发明人： Zhihao Yang , Thomas L. Penner , Ravi Sharma
IPC分类号： B41J2135
CPC分类号： B41J2/1646 , B41J2/1433 , B41J2/1606 , B41J2/162 , B41J2/1625 , B41J2/1642 , B41J2202/03 , B82Y10/00 , B82Y30/00
摘要： An ink jet nozzle plate is provided comprising an outer surface having a self-assembled monolayer thereon comprising a mixture of at least one hydrophobic compound and at least one ionic compound, which monolayer renders the outer surface non-wetting with respect to aqueous ink solutions. In accordance with preferred embodiments, the self-assembled monolayers comprises a mixture of hydrophobic alkyl thiols and charged alkyl thiols. An advantage of coatings in accordance with the invention is that they provide improved non-wetting characteristics after contact with ink.
摘要翻译：提供一种喷墨喷嘴板，其包括其上具有自组装单层的外表面，其上包含至少一种疏水化合物和至少一种离子化合物的混合物，所述单层使外表面相对于水性油墨溶液不润湿。根据优选实施方案，自组装单层包含疏水性烷基硫醇和带电的烷基硫醇的混合物。根据本发明的涂层的优点是它们在与油墨接触之后提供改善的非润湿特性。

5. 发明授权

US06296344B1 Method for replenishing coatings on printhead nozzle plate 有权
标题翻译：在打印头喷嘴板上补充涂层的方法
公开(公告)号：US06296344B1
公开(公告)日：2001-10-02
申请号：US09470813
申请日：1999-12-22
申请人： Ravi Sharma , Zhihao Yang , Thomas L. Penner
发明人： Ravi Sharma , Zhihao Yang , Thomas L. Penner
IPC分类号： B41J2165
CPC分类号： B82Y30/00 , B05D1/185 , B05D5/00 , B05D7/52 , B41J2/1606 , B41J2/162 , B41J2/164 , B82Y40/00
摘要： A method for replenishing fouled coatings on a nozzle plate for an ink jet printhead, the nozzle plate comprising the following layers in the order recited: i) a first monomolecular layer of an organic material having first and second functional groups, the first functional group of the first monomolecular layer being bound to the surface of the nozzle plate, and the second functional group of the first monomolecular layer being bound to a second monomolecular layer, and ii) the second monomolecular layer of an organic material having first and second functional groups, the first functional group of the second monomolecular layer being bound to the second functional group of the first monomolecular layer, and the second functional group of the second monomolecular layer being an anti-wetting group, the second monomolecular layer having been fouled; the method comprising A) unbinding the first functional group of the fouled second monomolecular layer so that it is no longer bound to the second functional group of the first monomolecular layer; B) removing the fouled second monomolecular layer; and C) reattaching a new, unfouled second monomolecular layer to the first monomolecular layer; the new, unfouled second monomolecular layer comprising an organic material having first and second functional groups, the first functional group of the second new, unfouled monomolecular layer being bound to the second functional group of the first monomolecular layer, and the second functional group of the new, unfouled second monomolecular layer being an anti-wetting group.
摘要翻译：一种用于在用于喷墨打印头的喷嘴板上补充污垢涂层的方法，喷嘴板按照所述顺序包括以下层：i）具有第一和第二官能团的有机材料的第一单分子层，第一官能团所述第一单分子层与所述喷嘴板的表面结合，并且所述第一单分子层的第二官能团与第二单分子层结合，以及ii）具有第一和第二官能团的有机材料的第二单分子层，第二单分子层的第一官能团与第一单分子层的第二官能团结合，第二单分子层的第二官能团为防润湿基团，第二单分子层已被污染; 所述方法包括：A）使结垢的第二单分子层的第一官能团与第一单分子层的第二官能团不再结合， B）去除被污染的第二单分子层; 和C）将新的未结合的第二单分子层重新附着到第一单分子层; 新的未结合的第二单分子层包含具有第一和第二官能团的有机材料，第二新的未结合单分子层的第一官能团与第一单分子层的第二官能团结合，第二官能团新的未结垢的第二单分子层是抗潮湿组。

6. 发明授权

US06345881B1 Coating of printhead nozzle plate 失效
标题翻译：打印头喷嘴板涂层
公开(公告)号：US06345881B1
公开(公告)日：2002-02-12
申请号：US09408193
申请日：1999-09-29
申请人： Zhihao Yang , Yung-Rai Lee , Thomas L. Penner , Ravi Sharma
发明人： Zhihao Yang , Yung-Rai Lee , Thomas L. Penner , Ravi Sharma
IPC分类号： B41J2135
CPC分类号： B82Y30/00 , B41J2/1606
摘要： A method for treating a metallic oxide or metallic nitride ink jet printhead nozzle plate comprising stamping the front surface thereof with an anti-wetting agent using an elastomeric stamp.
摘要翻译：一种用于处理金属氧化物或金属氮化物喷墨打印头喷嘴板的方法，包括使用弹性体印模将其前表面冲压成抗湿润剂。

7. 发明授权

US06896873B2 MR signal-emitting coatings 有权
标题翻译： MR信号发射涂层
公开(公告)号：US06896873B2
公开(公告)日：2005-05-24
申请号：US10096368
申请日：2002-03-12
申请人： Richard Frayne , Charles M. Strother , Orhan Unal , Zhihao Yang , Abukar Wehelie , Hyuk Yu
发明人： Richard Frayne , Charles M. Strother , Orhan Unal , Zhihao Yang , Abukar Wehelie , Hyuk Yu
IPC分类号： A61B5/055 , A61K49/08 , A61L29/18 , A61L31/18
CPC分类号： A61K49/12 , A61K49/085 , A61K49/18 , A61L29/18 , A61L31/18
摘要： The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex.
摘要翻译：本发明提供了发射磁共振信号的涂层和用于涂覆医疗装置的方法。该涂层包括含顺磁金属离子的聚合物复合物，其通过容易地观察涂覆有复合物的医疗装置来促进诊断和治疗技术。

8. 发明授权

US06568799B1 Drop-on-demand ink jet printer with controlled fluid flow to effect drop ejection 失效
标题翻译：具有受控流体流动的点滴式喷墨打印机以实现液滴喷射
公开(公告)号：US06568799B1
公开(公告)日：2003-05-27
申请号：US10055295
申请日：2002-01-23
申请人： Zhihao Yang , Ravi Sharma , Christopher N. Delametter , Milton S. Sales
发明人： Zhihao Yang , Ravi Sharma , Christopher N. Delametter , Milton S. Sales
IPC分类号： B41J275
CPC分类号： B41J2/14 , B41J2202/12
摘要： A drop on demand microfluidic ink jet printing system includes an ink flow chamber having a nozzle opening in a wall of the flow chamber through which ink droplets are ejected when ink in the flow chamber is at or above a predetermined positive pressure. An inlet channel opens into the flow chamber to supply thermally-responsive ink to the flow chamber at or above the predetermined pressure. A microfluidic outlet channel communicates the flow chamber with a low pressure ink reservoir such that thermally-responsive ink is normally transported from the flow chamber at a flow velocity sufficient to maintain ink in the flow chamber at a pressure less than the predetermined positive pressure. A valve selectively restricts the flow of the thermally-responsive ink through the microfluidic outlet channel sufficiently to cause an increase in ink pressure in the flow chamber to at least the predetermined positive pressure, the valve including a heater in contact with at least a portion of the associated microfluidic outlet channel, whereby the viscosity of the thermally-responsive ink can selectively be increased by heat from the heater to restrict the flow of the thermally-responsive ink from the flow chamber such that an ink droplet is ejected through the nozzle opening.
摘要翻译：按需微型喷墨打印系统包括墨水流动室，其具有在流动室的壁中的喷嘴开口，当流动室中的墨水处于或高于预定的正压时，通过该喷嘴开口喷射墨滴。入口通道通向流动室，以在预定压力或高于预定压力的情况下向流动室供应热响应性油墨。微流出口通道将流动室与低压储墨器连通，使得热响应性油墨通常以足以将流动室中的墨维持在小于预定正压力的压力的流速从流动室输送。阀选择性地限制热响应性油墨通过微流体出口通道的流动，足以使流动室中的油墨压力增加到至少预定的正压，该阀包括与至少一部分相关联的微流体出口通道，由此热响应性油墨的粘度可以通过来自加热器的热量而选择性地增加，以限制来自流动室的热响应性油墨的流动，使得墨滴通过喷嘴开口喷射。

9. 发明申请

US20070077349A1 Patterning OLED device electrodes and optical material 审中-公开
标题翻译：图案化OLED器件电极和光学材料
公开(公告)号：US20070077349A1
公开(公告)日：2007-04-05
申请号：US11241370
申请日：2005-09-30
申请人： David Newman , Timothy Tredwell , Ronald Cok , Zhihao Yang
发明人： David Newman , Timothy Tredwell , Ronald Cok , Zhihao Yang
IPC分类号： B05D5/12 , B29C71/02
CPC分类号： H01L51/5228 , B82Y20/00 , B82Y30/00 , H01L27/3213 , H01L27/322 , H01L27/3244 , H01L51/5212 , H01L51/5234 , H01L51/5268 , H01L51/5275 , H01L51/5284 , H01L2251/5315 , H01L2251/5369
摘要： A method of making an OLED display having a plurality of OLED devices includes providing a plurality of OLED devices on a substrate, such OLED devices sharing a common light-transmissive electrode; forming a patterned conductive layer structure over the common light-transmissive electrode to define wells in alignment with emissive areas of one or more OLED devices; and providing optical material into one or more wells
摘要翻译：制造具有多个OLED器件的OLED显示器的方法包括在衬底上提供多个OLED器件，所述OLED器件共享公共透光电极; 在所述公共透光电极上形成图案化导电层结构，以限定与一个或多个OLED器件的发射区域对齐的阱; 并将光学材料提供到一个或多个孔中

10. 发明授权

US06638693B2 Process for making media for high quality ink jet printing 失效
标题翻译：制造高质量喷墨打印介质的方法
公开(公告)号：US06638693B2
公开(公告)日：2003-10-28
申请号：US10046024
申请日：2001-10-29
申请人： Constantine N. Anagnostopoulos , Emmanuel K. Dokyi , Ravi Sharma , Mridula Nair , Zhihao Yang
发明人： Constantine N. Anagnostopoulos , Emmanuel K. Dokyi , Ravi Sharma , Mridula Nair , Zhihao Yang
IPC分类号： G03C500
CPC分类号： B41M5/52 , B32B27/10 , B41M5/506 , B41M5/5227 , B41M5/5254 , B41M5/5272 , B41M5/5281 , Y10T428/24802
摘要： Disclosed is media for receiving jetted ink comprising a support bearing a predetermined array of three dimensional cells composed of hydrophobic walls and having a hydrophilic base, the cross-section of the cells parallel to the support being of a size sufficiently small so as to increase the range of color density gradations attainable.
摘要翻译：公开了一种用于接收喷射墨的介质，其包括支撑由疏水壁组成并具有亲水基底的预定阵列的三维单元的支撑体，平行于支撑件的单元的横截面尺寸足够小以增加颜色浓度范围可达到。

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