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    • 4. 发明授权
    • Sensitivity and specificity of pulmonary edema detection when using transthoracic impedance
    • 使用经胸阻塞时肺水肿检测的灵敏度和特异性
    • US09089275B2
    • 2015-07-28
    • US11126723
    • 2005-05-11
    • Jeffrey E. StahmannJohn HatlestadJesse W. Hartley
    • Jeffrey E. StahmannJohn HatlestadJesse W. Hartley
    • A61B5/053
    • A61B5/053A61B5/0537A61B5/4869A61M2230/40A61M2230/65A61N1/36521A61N1/37282
    • This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.
    • 该专利文献尤其涉及用于增强肺水肿检测的系统,装置和方法,除胸部阻抗之外,还包括以下之一或组合:关于受试者的生理信息,至少一个统计参数, 可编程检测水平,与先前的肺水肿事件相关联的至少一个参数,以及关于受试者的患者症状信息。 在一个示例中,(基底)胸部阻抗阈值被修改为经调整的胸部阻抗阈值。 与基础胸廓阻抗阈值相比,经调整的胸廓阻抗阈值提供了肺水肿检测的灵敏度增加。 在另一示例中,基于由本系统,设备和方法确定的肺水肿指示,向受检者,照顾者或其他用户提供警报。 在另一个实例中,响应于肺水肿指示调整或启动治疗(提供给受试者)。
    • 8. 发明授权
    • Enhancements to the detection of pulmonary edema when using transthoracic impedance
    • 使用经胸阻抗检测肺水肿的增强
    • US08483818B2
    • 2013-07-09
    • US13033081
    • 2011-02-23
    • Jeffrey E. StahmannJohn D. HatlestadJesse W. Hartley
    • Jeffrey E. StahmannJohn D. HatlestadJesse W. Hartley
    • A61B5/05A61B5/04A61N1/00
    • A61B5/0537A61B5/0002A61B5/0538A61B5/4869A61B5/4878
    • This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.
    • 该专利文献尤其涉及用于增强肺水肿检测的系统,装置和方法,除胸部阻抗之外,还包括以下之一或组合:关于受试者的生理信息,至少一个统计参数, 可编程检测水平,与先前的肺水肿事件相关联的至少一个参数,以及关于受试者的患者症状信息。 在一个示例中,(基底)胸部阻抗阈值被修改为经调整的胸部阻抗阈值。 与基础胸廓阻抗阈值相比,经调整的胸廓阻抗阈值提供了肺水肿检测的灵敏度增加。 在另一示例中,基于由本系统,设备和方法确定的肺水肿指示,向受检者,照顾者或其他用户提供警报。 在另一个实例中,响应于肺水肿指示调整或启动治疗(提供给受试者)。
    • 9. 发明授权
    • Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia
    • 用于治疗不规则心室收缩的方法和装置,例如在心房心律失常期间
    • US08064997B2
    • 2011-11-22
    • US11423516
    • 2006-06-12
    • David B. KrigJesse W. HartleyWyatt StahlJeffrey E. Stahmann
    • David B. KrigJesse W. HartleyWyatt StahlJeffrey E. Stahmann
    • A61N1/362
    • A61N1/3956A61N1/3622A61N1/395
    • A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
    • 心律管理系统能够治疗不规则的心室心脏收缩,例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔(例如传感器指示的起搏间隔)来提供起搏疗法。 诸如无限脉冲响应(IIR)滤波器的加权平均器调节感测节拍的第一个起搏间隔,并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化,但是当心室节律稳定时,可抑制起搏。