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1. 发明授权

US4623541A Production of purified porcine immunoglobulins 失效
标题翻译：生产纯化的猪免疫球蛋白
公开(公告)号：US4623541A
公开(公告)日：1986-11-18
申请号：US748671
申请日：1985-06-25
申请人： James I. Elliot , Gordon E. Timbers , H. Wayne Modler , Robert W. Allen
发明人： James I. Elliot , Gordon E. Timbers , H. Wayne Modler , Robert W. Allen
IPC分类号： A61K38/00 , C07K16/06 , A61K35/16 , A61K39/395
CPC分类号： C07K16/065 , A61K38/00 , Y10S530/832 , Y10S530/833
摘要： A method for the continuous production of a purified immunoglobulin preparation wherein the antibodies are substantially enriched by means of a selective two-step ammonium sulfate fractionation procedure employing centrifugation and ion depletion processes. The purified immunoglobulins are subsequently commingled with condensed skim milk and spray dried. The resulting product for example is employed in the formulation of milk replacers for artificial rearing of neonatal pigs to provide the passive immunity to disease normally provided by sows' colostrum and later milk.
摘要翻译：用于连续生产纯化免疫球蛋白制剂的方法，其中所述抗体通过使用离心和离子消耗过程的选择性两步硫酸铵分级方法基本上富集。然后将纯化的免疫球蛋白与冷凝的脱脂乳混合并喷雾干燥。所得到的产品例如用于制备用于新生猪的人工饲养的牛奶替代品，以提供通常由母猪的初乳和后来的牛奶提供的疾病的被动免疫。

2. 发明授权

US4278660A Complex or salt of a platinum (II) compound and a nitrogen containing polymer 失效
标题翻译：铂（II）化合物和含氮聚合物的络合物或盐
公开(公告)号：US4278660A
公开(公告)日：1981-07-14
申请号：US958976
申请日：1978-11-09
申请人： Harry R. Allcock , Robert W. Allen , John P. O'Brien
发明人： Harry R. Allcock , Robert W. Allen , John P. O'Brien
IPC分类号： C07F15/00 , A61K31/74 , A61K31/28 , A61K31/555
CPC分类号： C07F15/0093
摘要： A cis- complex or -salt of a square planar platinum compound and a nitrogen containing oligomer or polymer prepared by reacting a platinum (II) compound with a nitrogen containing oligomer or polymer in an organic solvent or an acidic aqueous medium, said complex or salt being useful for treating animal malignant tumor cells sensitive to cis-square planar platinum compounds.
摘要翻译：通过在有机溶剂或酸性水性介质中使铂（II）化合物与含氮低聚物或聚合物反应而制备的正方形平面铂化合物和含氮低聚物或聚合物的顺 - 络合物或盐，所述络合物或盐可用于治疗对顺式平面铂化合物敏感的动物恶性肿瘤细胞。

3. 发明授权

US08153372B2 Method for simultaneously determining in a single multiplex reaction gender of donors and quantities of genomic DNA and ratios thereof, presence and extent of DNA degradation, and PCR inhibition within a human DNA sample 有权
标题翻译：在单次多重反应中同时确定供体的性别和基因组DNA的量及其比例，DNA降解的存在和程度以及人类DNA样品内的PCR抑制的方法
公开(公告)号：US08153372B2
公开(公告)日：2012-04-10
申请号：US11960113
申请日：2007-12-19
申请人： Robert W. Allen , Valerie Fuller
发明人： Robert W. Allen , Valerie Fuller
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6879 , C12Q1/6851 , C12Q1/6876 , C12Q2600/16 , C12Q2537/143
摘要： Methods are provided for determining, in a single polymerase chain reaction (PCR) reaction, the quantity, quality, and gender of origin of DNA in a sample, and whether or not the sample contains PCR amplification inhibitors. The methods involve carrying out a single PCR multiplex reaction utilizing primer sets specific for amplifying the human amelogenin locus, an X- and/or Y-chromosome specific gene that is shorter than the amelogenin gene, and a heterologous, non-human reporter gene.
摘要翻译：提供了用于在单个聚合酶链反应（PCR）反应中测定样品中DNA的量，质量和性别以及样品是否含有PCR扩增抑制剂的方法。所述方法包括利用特异于扩增人类朊蛋白酶基因座的引物组，短于am原蛋白基因的X和/或Y-染色体特异性基因和异源非人类报道基因进行单个PCR多重反应。

4. 发明申请

US20080153099A1 Quantitation of Human Genomic DNA 有权
标题翻译：人基因组DNA的定量
公开(公告)号：US20080153099A1
公开(公告)日：2008-06-26
申请号：US11960113
申请日：2007-12-19
申请人： Robert W. Allen , Valerie Fuller
发明人： Robert W. Allen , Valerie Fuller
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6879 , C12Q1/6851 , C12Q1/6876 , C12Q2600/16 , C12Q2537/143
摘要： Methods are provided for determining, in a single polymerase chain reaction (PCR) reaction, the quantity, quality, and gender of origin of DNA in a sample, and whether or not the sample contains PCR amplification inhibitors. The methods involve carrying out a single PCR multiplex reaction utilizing primer sets specific for amplifying the human amelogenin locus, an X- and/or Y-chromosome specific gene that is shorter than the amelogenin gene, and a heterologous, non-human reporter gene.
摘要翻译：提供了用于在单个聚合酶链反应（PCR）反应中测定样品中DNA的量，质量和性别以及样品是否含有PCR扩增抑制剂的方法。所述方法包括利用特异于扩增人类朊蛋白酶基因座的引物组，短于am原蛋白基因的X和/或Y-染色体特异性基因和异源非人类报道基因进行单个PCR多重反应。

5. 发明授权

US4320743A Solar energy system and solar collector therefor 失效
标题翻译：太阳能系统和太阳能收集器
公开(公告)号：US4320743A
公开(公告)日：1982-03-23
申请号：US126996
申请日：1980-03-03
申请人： Robert W. Allen
发明人： Robert W. Allen
IPC分类号： F03G6/00 , F24J2/20 , F24J2/38 , F24J2/46 , F24J3/02
CPC分类号： F24J2/4649 , F03G6/00 , F24J2/204 , F24J2/38 , Y02E10/44 , Y02E10/46 , Y02E10/47
摘要： A solar collector for a solar energy system comprises a solar absorber for converting solar radiation into heat, a heat transfer fluid for transferring heat from the solar absorber, at least one passage for flow of the fluid in contact with the solar absorber surface, and apparatus for creating a relative vacuum in the at least one passage so as to minimize the creation of a stagnant boundary layer of the fluid when it is pumped through the at least one passage. The at least one passage is preferably formed by a convoluted surface on the solar absorber which defines at least one groove, and a flexible sheet which overlies the convoluted surface and sealingly engages the surface through the action of a vacuum. The heat transfer fluid preferably is selected from the group of mineral oil, aliphatic hydrocarbon oils, and silicone oils.
摘要翻译：用于太阳能系统的太阳能收集器包括用于将太阳辐射转换成热的太阳能吸收器，用于从太阳能吸收器传递热量的传热流体，用于与太阳能吸收器表面接触的流体流动的至少一个通道，以及装置用于在所述至少一个通道中产生相对真空，以便在泵送通过所述至少一个通道时最小化所述流体停滞边界层的产生。所述至少一个通道优选地由太阳能吸收器上的回旋表面形成，其限定了至少一个凹槽，以及柔性薄片，其覆盖在回旋表面上并通过真空的作用密封地接合表面。传热流体优选选自矿物油，脂族烃油和硅油。

6. 发明申请

US20140147849A1 QUANTITATION OF HUMAN GENOMIC AND MITOCHONDRIAL DNA 审中-公开
标题翻译：人类基因组和人类DNA的定量
公开(公告)号：US20140147849A1
公开(公告)日：2014-05-29
申请号：US13825508
申请日：2011-09-21
申请人： Robert W. Allen
发明人： Robert W. Allen
IPC分类号： C12Q1/68
CPC分类号： C12Q1/686 , C12Q1/6851 , C12Q1/6876 , C12Q1/6879 , C12Q2600/16 , C12Q2537/143
摘要： Methods are provided for determining, in a single polymerase chain reaction (PCR) reaction, the quantity, quality, and gender of origin of DNA in a sample, and whether or not the sample contains PCR amplification inhibitors. The methods involve carrying out a single PCR multiplex reaction utilizing primer sets specific for amplifying: the human amelogenin locus; an X- and/or Y-chromosome specific gene that is shorter than the amelogenin gene; at least one mitochondrial DNA sequence, and preferably two differently-sized mitochondrial sequences; and a heterologous, non-human reporter gene.
摘要翻译：提供了用于在单个聚合酶链反应（PCR）反应中测定样品中DNA的量，质量和性别以及样品是否含有PCR扩增抑制剂的方法。所述方法包括利用对扩增特异性的引物组进行单个PCR多重反应：人类蜕皮素蛋白基因座; 短于am原蛋白基因的X-和/或Y-染色体特异性基因; 至少一个线粒体DNA序列，优选两个不同大小的线粒体序列; 和异源非人类报道基因。

7. 发明授权

US4333314A Solar energy system and heat engine therefor 失效
标题翻译：太阳能系统及热机系列
公开(公告)号：US4333314A
公开(公告)日：1982-06-08
申请号：US126947
申请日：1980-03-03
申请人： Robert W. Allen
发明人： Robert W. Allen
IPC分类号： F01K25/06 , F03G3/00 , F03G6/00 , F01K7/00
CPC分类号： F01K25/06 , F03G3/00 , F03G6/005 , Y02E10/46
摘要： A heat engine comprises first and second tanks radially mounted for rotation with respect to an axis of rotation and so as to be spaced from each other, a conduit connecting the tanks for transfer of fluid therebetween, a relatively heavy fluid disposed in the tanks for transfer therebetween, apparatus for heating the heavy fluid, and apparatus for introducing a relatively volatile fluid in a condensed state into direct contact with the heavy fluid for vaporization of the volatile fluid at predetermined times during the rotation of the tanks about the axis of rotation such that the expansion of the vaporized volatile fluid causes the heavy fluid to be cyclically transferred from a predetermined one of the tanks to the other of the tanks so as to maintain the rotation of the tanks about the axis of rotation.
摘要翻译：热引擎包括径向安装的第一和第二储罐，用于相对于旋转轴线旋转并且彼此间隔开;连接罐的导管，用于在其间传送流体的导管，设置在罐中用于转移的相对重的流体其间用于加热重质流体的装置，以及用于将冷凝状态下的相对易挥发的流体引入与重质流体直接接触的装置，用于在容器围绕旋转轴旋转期间的预定时间使挥发性流体蒸发，使得蒸发的挥发性液体的膨胀导致重质流体从预定的一个罐循环转移到另一个罐中，以便保持槽围绕旋转轴的旋转。

8. 发明授权

US4305380A Solar energy system and solar powered tracking apparatus therefor 失效
标题翻译：太阳能系统及太阳能跟踪设备
公开(公告)号：US4305380A
公开(公告)日：1981-12-15
申请号：US126850
申请日：1980-03-03
申请人： Robert W. Allen
发明人： Robert W. Allen
IPC分类号： F24S10/50 , F24S50/20 , F24J3/02 , G03B21/00 , G01J1/20
CPC分类号： F24J2/38 , F24J2/204 , Y02E10/44 , Y02E10/47
摘要： Solar tracking apparatus for a solar energy system comprises at least one chamber containing a volatile fluid, a shading arrangement for controlling the degree to which the at least one chamber is exposed to the sun in dependence on the position of the sun so as to control the extent to which the fluid is vaporized due to solar heating of the at least one chamber, and apparatus for coupling the expansive force generated by vaporization of the fluid to a work piece to control the position, orientation, and/or operation thereof. Preferably, the solar tracking apparatus comprises a base pivotably mounted with respect to a pivot axis, first and second chambers mounted to the base in counterbalancing relationship with respct to the pivot axis, a conduit connecting the chambers for transfer to fluid therebetween, a volatile fluid disposed in the chambers for transfer therebetween, and a shading arrangement for controlling the degree to which each of the chambers is exposed to the sun such that a differential vapor pressure is created therebetween in dependence on the position of the sun which causes a predetermined transfer of the fluid between the chambers so as to change the proportion of the fluid disposed within each of the chambers and thereby cause the base to pivot into a predetermined orientation with respect to the position of the sun.
摘要翻译：用于太阳能系统的太阳能跟踪装置包括至少一个容纳挥发性流体的室，用于根据太阳的位置控制至少一个室暴露于太阳的程度的遮蔽装置，以便控制由于至少一个室的太阳能加热，流体被蒸发的程度，以及用于将由流体蒸发产生的膨胀力耦合到工件以控制其位置，取向和/或操作的装置。优选地，太阳能跟踪装置包括相对于枢转轴线可枢转地安装的基座，安装到基座的第一和第二腔室与抵抗枢转轴线的平衡关系，连接腔室以转移到其间的流体的导管，挥发性流体设置在用于在其间转移的室中的遮光装置和用于控制每个室暴露于太阳的程度的遮光装置，使得根据太阳的位置而产生差异蒸气压，这导致预定的转印腔室之间的流体，以便改变设置在每个室内的流体的比例，从而使得基座相对于太阳的位置枢转到预定的方位。

9. 发明授权

US4151185A Complex or salt of a platinum (II) compound and a nitrogen containing polymer 失效
标题翻译：铂（II）化合物和含氮聚合物的络合物或盐
公开(公告)号：US4151185A
公开(公告)日：1979-04-24
申请号：US792608
申请日：1977-05-02
申请人： Harry R. Allcock , Robert W. Allen , John P. O'Brien
发明人： Harry R. Allcock , Robert W. Allen , John P. O'Brien
IPC分类号： C07F15/00
CPC分类号： C07F15/0093
摘要： A cis- complex or -salt of a square planar platinum compound and a nitrogen containing oligomer or polymer prepared by reacting a platinum (II) compound with a nitrogen containing oligomer or polymer in an organic solvent or an acidic aqueous medium, said complex or salt being useful as an anti-cancer agent.
摘要翻译：通过在有机溶剂或酸性水性介质中使铂（II）化合物与含氮低聚物或聚合物反应而制备的正方形平面铂化合物和含氮低聚物或聚合物的顺 - 络合物或盐，所述络合物或盐作为抗癌剂有用。

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