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1. 发明授权

US5952321A Substituted azetidinones as anti-inflammatory and antidegenerative agents 失效
标题翻译：取代的氮杂环丁酮作为抗炎和抗再生剂
公开(公告)号：US5952321A
公开(公告)日：1999-09-14
申请号：US764775
申请日：1996-12-12
申请人： James Doherty , Conrad Dorn , Philippe Durette , Paul Finke , Malcolm Maccoss , Sander Mills , Shrenik Shah , Soumya Sahoo , William Hagmann , Scott Polo
发明人： James Doherty , Conrad Dorn , Philippe Durette , Paul Finke , Malcolm Maccoss , Sander Mills , Shrenik Shah , Soumya Sahoo , William Hagmann , Scott Polo
IPC分类号： A61K31/395 , A61K31/397 , A61K31/40 , A61K31/4427 , A61K31/445 , A61K31/495 , A61K31/535 , A61K31/54 , A61P29/00 , C07D205/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D417/12
CPC分类号： C07D401/12 , C07D205/08 , C07D403/12 , C07D405/12
摘要： New substituted azetidinones of the general Formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described, wherein n is
摘要翻译：描述了已经被发现是有效的弹性蛋白酶抑制剂和由此有用的抗炎和抗代谢剂的通式（I）的新的取代的氮杂环丁酮，其中n为0

2. 发明授权

US5747485A Substituted azetidiones as anti-inflammatory and antidegenerative agents 失效
标题翻译：取代的氮杂环丁酮作为抗炎剂和抗再生剂
公开(公告)号：US5747485A
公开(公告)日：1998-05-05
申请号：US848076
申请日：1997-06-05
申请人： James Doherty , Conrad Dorn , Philippe Durette , Paul Finke , Malcolm Maccoss , Sander Mills , Shrenik Shah , Soumya Sahoo , William Hagmann , Jeffrey Hale , Thomas Lanza
发明人： James Doherty , Conrad Dorn , Philippe Durette , Paul Finke , Malcolm Maccoss , Sander Mills , Shrenik Shah , Soumya Sahoo , William Hagmann , Jeffrey Hale , Thomas Lanza
IPC分类号： A61K31/397 , A61K31/496 , A61K31/5377 , A61K31/395
CPC分类号： A61K31/496 , A61K31/397 , A61K31/5377
摘要： Substituted azetidinones are herein disclosed for use in the treatment of various elastase-mediated diseases.
摘要翻译：本文公开了取代的氮杂环丁酮，用于治疗各种弹性蛋白酶介导的疾病。

3. 发明授权

US08908561B2 Enhanced mobile network system acquisition using scanning triggers 有权
标题翻译：使用扫描触发器增强移动网络系统采集
公开(公告)号：US08908561B2
公开(公告)日：2014-12-09
申请号：US12562698
申请日：2009-09-18
申请人： Kevin R. Krause , Ayaz S. Kassam , James Doherty , Ki Hak Yi
发明人： Kevin R. Krause , Ayaz S. Kassam , James Doherty , Ki Hak Yi
IPC分类号： H04L12/26 , H04B7/185 , H04W4/00 , H04L12/28 , H04W48/16 , H04W88/06 , H04W36/14
CPC分类号： H04W48/16 , H04W36/14 , H04W88/06
摘要： A system and method for executing network acquisition employ a triggered scan for network acquisition regardless of the recorded optimal nature of the current network. In general, when one or more predefined conditions occur, a network scan is initiated to identify another network, if any, that is more optimal than the current network. Example trigger conditions include failed registration attempts, exceeding a predetermined distance threshold, entry to or exit from a pre-determined region, excess CDMA Chip delay, and others. Triggers may be used singly or in Boolean combinations. In this way, network scanning occurs when it may be beneficial, but will not be initiated too frequently or in situations where connectivity may not actually be suboptimal. This triggered scan provides improved connectivity, and can allow the device to make and receive calls in locations where it would otherwise not have been possible.
摘要翻译：用于执行网络采集的系统和方法采用触发扫描进行网络采集，而不管当前网络的记录的最佳性质如何。通常，当发生一个或多个预定义条件时，启动网络扫描以识别比当前网络更优化的另一网络（如果有的话）。示例触发条件包括失败的注册尝试，超过预定距离阈值，进入或退出预定区域，过多的CDMA芯片延迟等。触发器可以单独使用或以布尔组合使用。以这种方式，当网络扫描可能是有益的，但是不会太频繁地发起，或者在连接可能不是不是最佳的情况下发生。这种触发扫描提供了改进的连接性，并且可以允许设备在不可能的地方进行和接收呼叫。

4. 发明申请

US20120244850A1 MEID-BASED PAGING TO REACH DE-ACTIVATED TELEMATICS MODULES 有权
标题翻译：基于MEID的寻呼到达激活的电话模块
公开(公告)号：US20120244850A1
公开(公告)日：2012-09-27
申请号：US13070712
申请日：2011-03-24
申请人： James Doherty , Ki Hak Yi
发明人： James Doherty , Ki Hak Yi
IPC分类号： H04W4/04
CPC分类号： H04L67/12 , H04L61/157 , H04L61/2076 , H04L61/609 , H04W4/021 , H04W4/046
摘要： A method of operating a telematics unit includes replacing a mobile identification number (MIN) or a mobile dialed number (MDN) stored in a telematics unit with a temporary geographical mobile identification number (GMIN) that prevents the telematics unit from using all of its features; associating the GMIN with a mobile equipment identification number (MEID) of the vehicle telematics unit; storing the associated GMIN and MEID at a central facility; paging the telematics unit using the associated GMIN and MEID; and instructing the telematics unit via the page to communicate with the central facility over a wireless data connection.
摘要翻译：操作远程信息处理单元的方法包括用临时地理移动识别号码（GMIN）替换存储在远程信息处理单元中的移动识别号码（MIN）或移动拨号号码（MDN），该临时地理移动识别号码防止远程信息处理单元使用其所有特征 ; 将GMIN与车辆远程信息处理单元的移动设备标识号（MEID）相关联; 将相关的GMIN和MEID存储在中央设施; 使用关联的GMIN和MEID对远程信息处理单元进行寻呼; 并且经由该页面指示远程信息处理单元通过无线数据连接与中央设施进行通信。

5. 发明申请

US20120147863A1 METHOD OF VALIDATING 1X PACKET AVAILABILITY IN A VEHICLE TELEMATICS UNIT 有权
标题翻译：在车辆电话单元中验证1X分组可用性的方法
公开(公告)号：US20120147863A1
公开(公告)日：2012-06-14
申请号：US12963940
申请日：2010-12-09
申请人： James Doherty , Ki Hak Yi
发明人： James Doherty , Ki Hak Yi
IPC分类号： H04W4/20
CPC分类号： H04W76/025 , H04L67/12 , H04W4/046 , H04W4/20 , H04W76/15
摘要： A method of communicating with a telematics-equipped vehicle includes receiving a circuit-switched telephone call at a central facility from a telematics-equipped vehicle via a wireless carrier system that is in local communication with the telematics-equipped vehicle; determining during the circuit-switched telephone call that a separate packet-data communication session between the telematics-equipped vehicle and the central facility is desired; identifying the wireless carrier system that is in local communication with the telematics-equipped vehicle; querying the identified wireless carrier system from the central facility to determine whether the telematics-equipped vehicle is authorized to establish a packet-data communication session using the identified wireless carrier system; if so, obtaining an Internet protocol (IP) address from the identified wireless carrier system; and commencing the exchange of data between the telematics-equipped vehicle and the central facility using the obtained IP address.
摘要翻译：与配备有远程通讯业务的车辆进行通信的方法包括经由与配备远程通讯业务的车辆进行本地通信的无线载波系统的来自具有远程信息处理的车辆的中央设备的电路交换电话呼叫; 在电路交换电话呼叫期间确定期望具有远程信息处理的车辆与中央设施之间的单独的分组数据通信会话; 识别与配备有远程信息处理的车辆本地通信的无线载波系统; 从所述中央设施查询所识别的无线载波系统，以确定是否授权所述远程信息处理车辆使用所识别的无线载波系统建立分组数据通信会话; 如果是，从所识别的无线载波系统获得互联网协议（IP）地址; 并使用获得的IP地址开始在配备远程通讯业的车辆和中央设施之间交换数据。

6. 发明申请

US20080032951A1 Ophthalmic Compositions For Treating Ocular Hypertension 失效
标题翻译：用于治疗眼高血压的眼用组合物
公开(公告)号：US20080032951A1
公开(公告)日：2008-02-07
申请号：US11630172
申请日：2005-07-15
申请人： James Doherty , Dong-Ming Shen
发明人： James Doherty , Dong-Ming Shen
IPC分类号： A61K31/675 , A61P25/24 , A61P25/28 , A61P27/02 , C07F9/09
CPC分类号： C07D231/56 , C07F9/65038
摘要： This invention relates to potent potassium channel blocker compounds of Formula (I) or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
摘要翻译：本发明涉及式（I）的有效钾通道阻断剂化合物或其制剂用于治疗青光眼和导致患者眼睛中眼内压升高的其它病症。本发明还涉及这些化合物对哺乳动物物种尤其是人的眼睛的神经保护作用的用途。

7. 发明申请

US20070129372A1 P38 kinase inhibiting agents 失效
标题翻译： P38激酶抑制剂
公开(公告)号：US20070129372A1
公开(公告)日：2007-06-07
申请号：US11602782
申请日：2006-11-21
申请人： Meng-Hsin Chen , James Doherty , Robert Tynebor
发明人： Meng-Hsin Chen , James Doherty , Robert Tynebor
IPC分类号： A61K31/503 , C07D487/04
CPC分类号： C07D455/02 , C07D471/04
摘要： Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.
摘要翻译：由化学式（I）或其药学上可接受的盐描述的化合物是p38的抑制剂，可用于治疗炎症，例如治疗类风湿性关节炎，类风湿性脊椎炎，骨关节炎，痛风性关节炎和其他关节炎病症; 发炎关节，湿疹，牛皮癣或其他炎症皮肤病如晒伤; 炎症性眼病，包括结膜炎; 皮肤炎，疼痛等与炎症有关的病症。

8. 发明申请

US20060225902A1 Method of operating a combustion -powered tool 有权
公开(公告)号：US20060225902A1
公开(公告)日：2006-10-12
申请号：US11446684
申请日：2006-06-05
申请人： Larry Moeller , Joseph Fabin , James Doherty , Kui-Chiu Kwok , Yury Shkolnikov
发明人： Larry Moeller , Joseph Fabin , James Doherty , Kui-Chiu Kwok , Yury Shkolnikov
IPC分类号： B25B21/02
CPC分类号： B25C1/08
摘要： A combustion-powered fastener-driving tool includes a combustion-powered power source, at least one fan for associated with the power source, at least one temperature sensing device in operational proximity to the power source and a control system operationally associated with the power source and connected to the at least one fan and at least one temperature sensing device for adjusting the length of time for energizing the at least one cooling fan as a function of power source temperature sensed by the at least one temperature sensing device.

9. 发明申请

US20060054014A1 Non-symmetrical seal plate and valve housing 失效
公开(公告)号：US20060054014A1
公开(公告)日：2006-03-16
申请号：US10940923
申请日：2004-09-14
申请人： James Doherty
发明人： James Doherty
IPC分类号： F15B13/04
CPC分类号： F15B13/0817 , F15B13/0871 , F15B13/0896
摘要： A hydraulic assembly has a first fluid valve and a second fluid valve. A switching valve having a first fluid input and a second fluid input also has a fluid output. The first fluid input is in fluid communication with the first fluid valve while the second fluid input is in fluid communication with the second fluid valve. The switching valve is configured to switch fluid communication to the fluid output between the first fluid input and the second fluid input. A fluid actuator is in fluid communication with the fluid output. A housing for the switching valve is provided. The housing has a first portion and a second portion. The first portion has a first fluid passage permitting fluid communication between the first fluid valve and the first fluid input and a second fluid passage permitting fluid communication between the second fluid valve and the second fluid input. The first fluid passage has a first opening and the second fluid passage has a second opening. The second portion has a first seal to seal the first opening and a second seal to seal the second opening.

10. 发明申请

US20050256117A1 Ophthalmic compositions for treating ocular hypertension 审中-公开
公开(公告)号：US20050256117A1
公开(公告)日：2005-11-17
申请号：US10511636
申请日：2003-06-11
申请人： Meng Hsin Chen , Luping Liu , Peter Meinke , Ravi Natarajan , William Parsons , Dong-Ming Shen , Min Shu , John Stelmach , Harold Wood , Fengqi Zhang , David Wisnoski , James Doherty
发明人： Meng Hsin Chen , Luping Liu , Peter Meinke , Ravi Natarajan , William Parsons , Dong-Ming Shen , Min Shu , John Stelmach , Harold Wood , Fengqi Zhang , David Wisnoski , James Doherty
IPC分类号： A61K9/08 , A61K9/10 , A61K31/404 , A61K31/41 , A61K31/427 , A61K31/4439 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/7056 , A61K45/00 , A61K47/36 , A61P3/10 , A61P9/06 , A61P25/24 , A61P25/28 , A61P27/02 , A61P27/06 , A61P27/12 , A61P43/00 , C07D209/08 , C07D209/10 , C07D209/12 , C07D209/18 , C07D401/06 , C07D403/10 , C07D409/12 , C07D413/02 , C07D417/02 , C07D417/12 , C07D417/14 , C07H15/26 , C07D43/02
CPC分类号： C07D401/06 , C07D209/12 , C07D209/18 , C07D403/10 , C07D409/12 , C07D417/12 , C07D417/14 , C07H15/26
摘要： This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.

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