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1. 发明申请

US20060188589A1 Oral care compositions derived from the Labiatae family 有权
公开(公告)号：US20060188589A1
公开(公告)日：2006-08-24
申请号：US11334719
申请日：2006-01-18
申请人： Igor Mezine , Huizhen Zhang , Mike Petteruti , Mary Opet , John Finley
发明人： Igor Mezine , Huizhen Zhang , Mike Petteruti , Mary Opet , John Finley
IPC分类号： A61K36/534
CPC分类号： A61Q11/00 , A61K8/73 , A61K8/731 , A61K8/97 , A61K9/0063 , A61K31/715 , A61K36/53 , A61K36/534 , A61K45/06 , A61K2300/00
摘要： The invention relates to water dispersible extract preparations derived from water soluble components of Labiatae family plant material, including plant material hay and previously extracted or spent hay, which possesses beneficial oral care properties, methods of their manufacturing and application of the preparations in oral care products.

2. 发明授权

US07517541B2 Oral care compositions derived from the Labiatae family 有权
标题翻译：来自Labiatae家族的口腔护理组合物
公开(公告)号：US07517541B2
公开(公告)日：2009-04-14
申请号：US11334719
申请日：2006-01-18
申请人： Igor Mezine , Huizhen Zhang , Mike Petteruti , Mary Opet , John Finley
发明人： Igor Mezine , Huizhen Zhang , Mike Petteruti , Mary Opet , John Finley
IPC分类号： A61K36/534
CPC分类号： A61Q11/00 , A61K8/73 , A61K8/731 , A61K8/97 , A61K9/0063 , A61K31/715 , A61K36/53 , A61K36/534 , A61K45/06 , A61K2300/00
摘要： The invention relates to water dispersible extract preparations derived from water soluble components of Labiatae family plant material, including plant material hay and previously extracted or spent hay, which possesses beneficial oral care properties, methods of their manufacturing and application of the preparations in oral care products.
摘要翻译：本发明涉及衍生自Labiatae家族植物材料的水溶性成分的水分散性提取物制剂，包括植物材料干草和先前提取的或已用过的干草，其具有有益的口腔护理性质，其在口腔护理产品中的制备和应用方法。

3. 发明申请

US20060172012A1 ANTI-INFLAMMATORY SUPPLEMENT COMPOSITIONS AND REGIMENS TO REDUCE CARDIOVASCULAR DISEASE RISKS 审中-公开
标题翻译：抗炎药补充组合物和减少心血管疾病风险的方案
公开(公告)号：US20060172012A1
公开(公告)日：2006-08-03
申请号：US11275717
申请日：2006-01-25
申请人： John Finley , Igor Mezine , John Finley , Song Gao , Irene Hoyt , Mary Opet , Huizhen Zhang
发明人： John Finley , Igor Mezine , John Finley , Song Gao , Irene Hoyt , Mary Opet , Huizhen Zhang
IPC分类号： A61K35/60 , A61K36/82 , A61K36/45 , A61K36/906 , A61K36/73 , A61K36/87 , A61K31/355
CPC分类号： A61K36/73 , A23C9/13 , A23G3/48 , A23L13/42 , A23L23/00 , A23L33/105 , A23L33/115 , A23V2002/00 , A61K31/355 , A61K36/45 , A61K36/82 , A61K36/87 , A61K45/06 , A23V2200/326 , A23V2250/2112 , A23V2250/21166 , A23V2250/21 , A23V2250/214 , A23V2250/2106 , A61K2300/00
摘要： Disclosed are improvements in human nutrition involving a unique combination of natural products constituting anti-inflammatory compositions which can reduce cardiovascular disease risks as well as play a positive role in other conditions and diseases for which key indicators, especially selected from the group consisting of C-reactive protein (CRP) levels, cyclooxygenase-2 (COX-2), 5-lypoxygenase (5-LOX) expression and prostaglandin E2 (PGE-2) biosynthesis or any combination of these, are indicators. Therapeutic compositions preferably comprise curcumin, bilberry extract, grape seed extract, green tea extract and apple extract, in effective amounts individually and combined to provide a therapeutically significant reduction in one or more key indicators. Another exemplified therapeutic composition comprises: omega-3 rich refined fish oil, resveratrol, blueberry extract, grape seed extract, green tea extract and gamma and/or delta tocopherol, in effective amounts individually for the above benefits.
摘要翻译：公开了人体营养的改善，其涉及构成抗炎组合物的天然产物的独特组合，其可以降低心血管疾病风险，并且在其它条件和疾病中发挥积极作用，其中关键指标，特别是选自C- 反应蛋白（CRP）水平，环氧合酶-2（COX-2），5-裂解加氧酶（5-LOX）表达和前列腺素E2（PGE-2）生物合成或这些的任何组合都是指标。治疗组合物优选包含姜黄素，越桔提取物，葡萄籽提取物，绿茶提取物和苹果提取物，其有效量单独和组合以提供一个或多个关键指标的治疗上显着的减少。另一个例举的治疗组合物包含以下有益的量：富含ω-3的精制鱼油，白藜芦醇，蓝莓提取物，葡萄籽提取物，绿茶提取物和γ和/或δ生育酚。

4. 发明申请

US20060154986A1 A TRIACYLGLYCERIDE TO DELIVER HEALTH PROMOTING FATTY ACIDS TO THE UPPER GASTROINTESTINAL TRACT AND SKIN 审中-公开
标题翻译：将三氯乙酸提供健康促进脂肪酸加入上胃肠外皮肤和皮肤
公开(公告)号：US20060154986A1
公开(公告)日：2006-07-13
申请号：US11275495
申请日：2006-01-10
申请人： John Finley , Igor Mezine
发明人： John Finley , Igor Mezine
IPC分类号： A61K31/22
CPC分类号： A61K31/225 , A61K31/22 , A61K31/23 , A61K31/231
摘要： Improved triglyceride compositions, bearing both omega-3-usaturated fatty acids and short chain fatty acids, are prepared according to the formulae: wherein, each R, independently, is a fatty acid residue, either saturated or unsaturated, having between 2 and 40 carbons; each R′, independently, is a long chain omega-3-unsaturated fatty acid residue having between 16 and 40 carbons, preferably 18 to 22 carbons; and each R″, independently, is a short chain acid residue having 2 to 5 carbons, preferably 2 to 4 carbons, most preferably 2 to 3 carbons. Also described is a regimen for treating a medical problem associated with less than healthy stomach tissue that is responsive to treatment with a triglyceride mixture as defined above, in amounts and at intervals effective to therapeutically improve the health of the stomach tissue. In another aspect the compositions are used in a regime for treating skin to increase skin cell turnover, to provide nourishment to epithelial cells and reduce inflammation. The regime comprises topically administering to a mammal a triglyceride mixture as defined above, in amounts and at intervals effective for these purposes.
摘要翻译：具有ω-3-饱和脂肪酸和短链脂肪酸两者的改进的甘油三酯组合物根据下式制备：其中每个R独立地是饱和或不饱和的，具有2-40个碳原子的脂肪酸残基 ; 每个R'独立地是具有16至40个碳，优选18至22个碳的长链ω-3-不饱和脂肪酸残基; 并且每个R“独立地是具有2至5个碳，优选2至4个碳，最优选2至3个碳的短链酸残基。还描述了治疗与不良健康的胃组织相关的医学问题的方案，该方法响应于如上定义的甘油三酯混合物的治疗，以有效治疗性地改善胃组织健康的量和间隔。在另一方面，组合物用于治疗皮肤以增加皮肤细胞更替的方案，以向上皮细胞提供营养并减少炎症。该方案包括以对上述目的有效的量和间隔向哺乳动物局部施用如上定义的甘油三酯混合物。

5. 发明申请

US20160088136A1 Smartphone Based Meter and Injector 审中-公开
标题翻译：基于智能手机的仪表和注射器
公开(公告)号：US20160088136A1
公开(公告)日：2016-03-24
申请号：US14495509
申请日：2014-09-24
申请人： Paolo Di Donato , John Finley
发明人： Paolo Di Donato , John Finley
IPC分类号： H04M1/21 , A61B5/151 , A61M5/178 , A61B5/157 , A61B5/00 , H04W4/00 , A61B5/145
CPC分类号： H04M1/21 , A61B5/0002 , A61B5/14532 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/15087 , A61B5/151 , A61B5/15113 , A61B5/15186 , A61B5/157 , A61B5/4839 , A61B5/486 , A61B5/6898 , A61M5/003 , A61M5/178 , A61M5/28 , H04W4/80
摘要： One embodiment of the present invention incorporates a comprehensive blood glucose monitoring system into the case of a smartphone or other device that a patient normally carries with them. This system may include a glucose meter, lancets, test strips, logic to report the result of the blood test in the glucose meter, and a communication module to report the results to the smartphone. In addition, the system may also include small syringes of insulin concealed within the case or attached to the case. This would allow the user to inject if he or she needed to, after obtaining the results of the test.
摘要翻译：本发明的一个实施例将全面的血糖监测系统结合到患者通常携带的智能电话或其他装置的情况下。该系统可以包括葡萄糖计，刺血针，测试条，用于报告血糖仪中的血液测试结果的逻辑，以及将结果报告给智能手机的通信模块。此外，该系统还可以包括隐藏在壳体内或附着于壳体的胰岛素的小注射器。这将允许用户在获得测试结果后需要注入。

6. 发明申请

US20060141101A1 Delivery system for low calorie bulking agents 有权
标题翻译：低卡路里补充剂的配送系统
公开(公告)号：US20060141101A1
公开(公告)日：2006-06-29
申请号：US11025462
申请日：2004-12-29
申请人： Wen-Sherng Chen , John Finley , Bruce Campbell , Ariel Cudia
发明人： Wen-Sherng Chen , John Finley , Bruce Campbell , Ariel Cudia
IPC分类号： A23L1/00
CPC分类号： A21D2/36 , A21D2/18 , A23L7/109 , A23L7/115 , A23P10/30 , A23P10/35 , A23V2002/00 , A23V2200/224 , A23V2250/18 , A23V2250/54
摘要： The present invention generally relates to low calorie bulking agents (e.g., cellulose, starch, bran, glucans, hydrocolloids, and the like) coated with a lipid compound to form a base or inner layer and thereafter encapsulating the fiber/lipid complex within a protein compound as an outer layer. In effect, the present invention provides a delivery system for edible fibers wherein the moisture absorption by the edible fibers can be controlled. Using the encapsulated fiber of this invention, the absorption of water by the edible fiber (and thus the swelling of the edible fiber) can be effectively delayed until the encapsulated fiber reaches the stomach and normal digestive processes begin.
摘要翻译：本发明一般涉及涂覆有脂质化合物的低热量填充剂（例如，纤维素，淀粉，麸皮，葡聚糖，水胶体等）以形成碱或内层，然后将纤维/脂质复合物包封在蛋白质化合物作为外层。实际上，本发明提供了可食用纤维的输送系统，其中可控制食用纤维的吸湿性。使用本发明的包封的纤维，可以有效地延迟可食用纤维对水的吸收（因此可食用纤维的溶胀），直到包封的纤维达到胃并开始正常的消化过程。

7. 发明申请

US20050196504A1 Reduction of acrylamide in processed foods 审中-公开
标题翻译：加工食品中丙烯酰胺的还原
公开(公告)号：US20050196504A1
公开(公告)日：2005-09-08
申请号：US10793343
申请日：2004-03-04
申请人： John Finley
发明人： John Finley
IPC分类号： A23F5/16 , A23L5/20 , A23L19/18 , G01L1/20
CPC分类号： A23L19/18 , A23L5/27 , A23L5/273
摘要： Methods are provided for reducing the amounts of acrylamide and/or buteneamide in processed foods. The invention further relates to methods for treating processed foods with inhibitors, including organic amino compound, organic sulfhydryl compounds, and certain other compounds (e.g., disulfide reducing agents), to reduce the amount of acrylamide and/or buteneamide in processed food exposed to high temperature conditions (generally above about 110° C.) during manufacturing or cooking.
摘要翻译：提供了减少加工食品中丙烯酰胺和/或丁烯酰胺的量的方法。本发明还涉及用抑制剂处理加工食品的方法，包括有机氨基化合物，有机巯基化合物和某些其它化合物（例如二硫化物还原剂），以减少暴露于高的加工食品中的丙烯酰胺和/或丁烯酰胺的量温度条件（一般高于约110℃）。

8. 发明授权

US5647294A Boat with adjustable outriggers 失效
标题翻译：有可调式支腿的船
公开(公告)号：US5647294A
公开(公告)日：1997-07-15
申请号：US611389
申请日：1996-03-05
申请人： John Finley
发明人： John Finley
IPC分类号： B63B43/14
CPC分类号： B63B43/14 , B63B2001/145
摘要： A boat that has a central hull, a pair of floats, and a pair of outrigger spars for supporting the floats on each side of the hull. The outrigger spars are adjustably mounted on the hull so that the floats can be adjustably placed in a given range of positions that lie both (i) substantially spaced away outboard of the side beam of the central hull as well as (ii) substantially spaced rearward of the stern of the central hull. The floats are much smaller than the central hull, partly so that the central hull can be formed with storage recesses in the side-boards thereof for removably storing the floats in a stored position during non-use of the floats. The outrigger spars are preferably mounted to the central hull at or near the opposite rear corners thereof. Also, the outrigger spars are preferably mounted to the central hull for pivotal movement in generally horizontal planes. The boat further includes a set of locking mechanisms between the spars and the central hull, for releasably locking the spars in set positions. Additionally, the spars can be locked in position independently of each other and therefore need not be set in symmetric angles of divergence from the central hull.
摘要翻译：一艘船有一个中央船体，一对浮标和一对支腿，用于支撑船身两侧的浮标。外伸支架可调节地安装在船体上，使得浮子可以可调节地放置在给定的位置范围内，其位于（i）基本上间隔开的中央船体的侧梁的外侧，以及（ii）基本间隔开的后方的中央船体的船尾。浮体比中央船体小得多，部分地使得中央船体可以在其侧板中形成有存储凹槽，以在不使用浮子的过程中将浮子可移除地存储在存储位置。外伸支架优选地在其相对后角处或附近安装到中心船体。此外，外伸支架优选地安装到中心船体以在大致水平的平面中枢转运动。船还包括在翼梁和中央船体之间的一组锁定机构，用于将翼梁可释放地锁定在设定位置。此外，翼梁可以彼此独立地锁定就位，因此不需要设置成与中心船体发散的对称角度。

9. 发明申请

US20060035009A1 Compositions and processes for water-dispersible phytosterols and phytostanols 审中-公开
标题翻译：水分散植物甾醇和植物甾烷醇的组成和方法
公开(公告)号：US20060035009A1
公开(公告)日：2006-02-16
申请号：US10915147
申请日：2004-08-10
申请人： Anilkumar Gaonkar , Andrew McPherson , John Topinka , John Finley
发明人： Anilkumar Gaonkar , Andrew McPherson , John Topinka , John Finley
IPC分类号： A23G3/00
CPC分类号： A61K31/575 , A23L29/212 , A23L29/219 , A23L33/11 , A23V2002/00 , A23V2250/304 , A23V2250/21366 , A23V2250/5114 , A23V2250/21368
摘要： Plant sterols and plant sterol esters have been shown to be cholesterol-reducing agents in human serum. In the present invention, plant sterols and plant stanols are incorporated into compositions which are dispersible in water by complexing the hydrophobic lipids with water-soluble carbohydrates. The resulting plant sterol-carbohydrate complexes are in an aqueous or powder form which can be readily incorporated with food products in an amount effective to reduce serum cholesterol levels in a human consuming such food product, without adversely modifying the organoleptic properties of the food product.
摘要翻译：植物甾醇和植物甾醇酯已被证明是人血清中的胆固醇降低剂。在本发明中，植物甾醇和植物甾烷醇通过将疏水性脂质与水溶性碳水化合物络合而掺入到可分散于水中的组合物中。所得到的植物甾醇 - 碳水化合物复合物是水性或粉末形式，其可以容易地与食品中的食品一起掺入，以有效降低食用这种食品中的血清胆固醇水平，而不会不利地改变食品的感官特性。

10. 发明授权

US4999208A Extrusion baking of cookies having liposome encapsulated ingredients 失效
标题翻译：具有脂质体包封成分的饼干的挤压烘烤
公开(公告)号：US4999208A
公开(公告)日：1991-03-12
申请号：US362741
申请日：1989-06-07
申请人： Bernhard V. Lengerich , Lynn C. Haynes , Harry Levine , Michael S. Otterburn , Paul Mathewson , John Finley
发明人： Bernhard V. Lengerich , Lynn C. Haynes , Harry Levine , Michael S. Otterburn , Paul Mathewson , John Finley
IPC分类号： A21C11/16 , A21D8/02
CPC分类号： A21C11/163 , A21D8/02
摘要： A cookie product is prepared having a liposome-encapsulated component dispersed therein and leavened to a crumb-like structure. The liposomes substantially retain their structural integrity during the processing, mixing, and post extrusion baking and thus remain intact in the finished cookie. The liposomes may encapsulate flavorings, fragrances, preservatives, anti-staling agents, and other labile food additives. The liposomes may provide a sustained release of the encapsulant to the cookie during storage and prior to consumption. The encapsulant may be released when the cookie is baked or eaten by the consumer. The cookies are prepared by feeding the cookie ingredients to a blending zone of a cooker-extruder and heated to form a heat treated mass. A liposome-encapsulated component is added to the cooled heat treated mass and mixed at low pressure and temperature to prevent rupture of the liposomes. An optional source of water may also be admixed to form a dough-like mixture. The dough-like mixture is then extruded into shaped cookie pieces, and leavened by heating in an oven. The heat treating of the dough-like mixture in the cooker-extruder reduces the post extrusion baking time such that liposomes prepared from phospholipids having a high phase transition temperature substantially retain their structure integrity in the leavened cookie.
摘要翻译：制备其中分散有脂质体包封的组分并发酵成饼状结构的曲奇饼产品。脂质体在加工，混合和后挤压烘烤过程中基本保持其结构完整性，因此在成品的饼干中保持完整。脂质体可以包封调味剂，香料，防腐剂，抗陈化剂和其它不稳定的食品添加剂。脂质体可以在储存期间和消费之前提供密封剂到饼干的持续释放。当饼干被消费者烘烤或食用时，可以释放密封剂。通过将饼干成分加入到炊具 - 挤出机的混合区中并加热形成经热处理的物料来制备饼干。将脂质体包封的组分加入到冷却的热处理物质中，并在低压和低温下混合以防止脂质体破裂。也可以将可选的水源混合以形成面团状混合物。然后将面团状混合物挤压成成形的饼干块，并通过在烘箱中加热而发酵。在炊具 - 挤出机中的面团状混合物的热处理减少了后挤出烘烤时间，使得由具有高相变温度的磷脂制备的脂质体在发酵的饼干中基本保持其结构完整性。

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