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    • 5. 发明申请
    • PHOTODIODE FOR DETECTION WITHIN MOLECULAR DIAGNOSTICS
    • 用于在分子诊断中检测的光致抗体
    • US20090250630A1
    • 2009-10-08
    • US12374000
    • 2007-07-05
    • Pieter Jan Van Der ZaagIan FrenchNigel David Young
    • Pieter Jan Van Der ZaagIan FrenchNigel David Young
    • G01N21/64G01J1/58H01L31/105
    • H01L31/1055G01N21/6428H01L31/103
    • A photodiode (200), for instance a PN or a PIN photodiode, is disclosed. The photodiode receives incident radiation having first and second spectral distributions, where the first spectral distribution is spectrally shifted from the second spectral distribution. The photodiode has a first semiconductor layer (211) capable of absorbing incident radiation (231) having a first spectral distribution without generating a photocurrent, while simultaneously transmitting incident radiation having a second spectral distribution to the intrinsic layer (212) for generating a photocurrent (213). The photodiode may be used in connection with detecting the presence of target molecules that has been labeled with labeling agents, such as fluorophores or quantum dots. The labeling agents are characterized by the Stokes shift and, therefore, they emit fluorescent radiation having the second spectral distribution that is spectrally shifted from the illumination radiation having the first spectral distribution.
    • 公开了一种光电二极管(200),例如PN或PIN光电二极管。 光电二极管接收具有第一和第二光谱分布的入射辐射,其中第一光谱分布从第二光谱分布光谱偏移。 光电二极管具有能够吸收具有第一光谱分布而不产生光电流的入射辐射(231)的第一半导体层(211),同时将具有第二光谱分布的入射辐射传输到本征层(212)以产生光电流 213)。 光电二极管可用于检测已经用标记试剂如荧光团或量子点标记的靶分子的存在。 标记试剂的特征在于斯托克斯位移,因此,它们发射具有与具有第一光谱分布的照射辐射光谱偏移的第二光谱分布的荧光辐射。