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    • 1. 发明申请
    • Hydrogel composites
    • 水凝胶复合材料
    • US20050287191A1
    • 2005-12-29
    • US11146276
    • 2005-06-07
    • Hugh MunroPhilip AndrewsGareth JeffreySusana Sainz Garcia
    • Hugh MunroPhilip AndrewsGareth JeffreySusana Sainz Garcia
    • C08F2/44A61K9/70
    • C08F2/44Y10T442/2566
    • A method for producing a hydrogel/fibre composite comprises: impregnating fibres of a fibrous material with a precursor solution comprising at least one polymerisable, and optionally also crosslinkable, monomer such that at least partial swelling of the fibres takes place; and polymerising, and optionally also crosslinking, the at least one monomer after impregnation and at least partial swelling of the fibres such that the integrity of the fibrous material is at least partially preserved in the resulting hydrogel/fibre composite, provided that the crosslinking is not initiated solely by cation release from the fibres of the fibrous material. The invention provides a hydrogel/fibre composite prepared or preparable by the said method. The hydrogel/fibre composite may be adhesive to human skin with good properties of performance and subsequent painless removal. The composite is found to maintain acceptable strength and structural integrity on hydration or across one or more hydration/dehydration cycle, and thus finds use in, for example, biomedical products where this property is required.
    • 制备水凝胶/纤维复合材料的方法包括:用包含至少一种可聚合和任选地可交联的单体的前体溶液浸渍纤维材料的纤维,使得发生纤维的至少部分溶胀; 并且在浸渍之后聚合和任选地还交联至少一种单体,并且纤维的至少部分溶胀,使得纤维材料的完整性至少部分地保留在所得水凝胶/纤维复合材料中,条件是交联不是 仅由纤维材料纤维的阳离子释放引发。 本发明提供了通过所述方法制备或制备的水凝胶/纤维复合材料。 水凝胶/纤维复合材料可以具有良好的性能性能和随后的无痛去除对人体皮肤的粘合性。 发现复合材料在水合或一个或多个水化/脱水循环中保持可接受的强度和结构完整性,因此可用于例如需要该性质的生物医学产品。