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1. 发明申请

US20070282237A1 ABSORBENT MATERIALS AND ARTICLES 审中-公开
标题翻译：吸收材料和文章
公开(公告)号：US20070282237A1
公开(公告)日：2007-12-06
申请号：US11840536
申请日：2007-08-17
申请人： Hugh Munro , Philip Andrews , Susana Garcia
发明人： Hugh Munro , Philip Andrews , Susana Garcia
IPC分类号： A61F13/00
CPC分类号： A61L15/60 , Y10T442/15 , Y10T442/159 , Y10T442/164 , Y10T442/183 , Y10T442/2484 , Y10T442/2508 , Y10T442/2525
摘要： An absorbent material comprises a flexible, skin-conformable, moisture-absorbent sheet member, optionally a net member in sheet form overlying and associated with the absorbent sheet member on at least one face thereof, and a hydrogel disposed on at least one of the net member, when present, and the absorbent sheet member in an amount of less than about 500 g of hydrogel per square metre per face, wherein the aqueous saline absorbency rate of the absorbent material through the face on which the hydrogel is disposed is less than about 300 seconds. Absorbent articles comprising the absorbent material and methods of manufacturing the material or articles are also described.
摘要翻译：一种吸收性材料包括柔性的，适合皮肤的吸湿性片材构件，任选的在片材形式的网状构件，其在至少一个表面上覆盖并与吸收性片材构件相关联，以及水凝胶，其设置在至少一个网并且吸收性片材的用量小于约500g每平方米每面的水凝胶，其中通过其上设置水凝胶的面的吸收材料的盐水吸收率低于约 300秒还描述了包含吸收材料的吸收制品和制造材料或制品的方法。

2. 发明申请

US20060251880A1 Absorbent hydrogel composites 审中-公开
标题翻译：吸水性水凝胶复合材料
公开(公告)号：US20060251880A1
公开(公告)日：2006-11-09
申请号：US11287174
申请日：2005-11-23
申请人： Hugh Munro , Philip Andrews , Susana Sainz Garcia
发明人： Hugh Munro , Philip Andrews , Susana Sainz Garcia
IPC分类号： B32B3/26
CPC分类号： A61L15/425 , A61L15/60 , Y10T428/249953 , Y10T442/3935
摘要： The invention provides an absorbent material or article comprising an absorbent hydrogel composite sheet. The sheet includes an absorbent layer part having two major faces which comprises a flexible plasticised hydrophilic polymer matrix having an internal cellular structure, and a second part which comprises a flexible plasticised hydrophilic polymer matrix having a relatively continuous internal structure. The second part may be associated with the layer part such that the second part infiltrates some but not all of the cellular voids of the absorbent layer part over a major face of the absorbent layer part. Alternatively, the second part may be associated with the layer part such that the second part overlies a major face of the absorbent layer part. By this arrangement, some but not all of the absorbent layer part is effectively exposed for absorption of external water or other fluid through the side of the sheet corresponding to that said major face of the absorbent layer.
摘要翻译：本发明提供了一种包含吸收性水凝胶复合片材的吸收材料或制品。片材包括具有两个主表面的吸收层部分，其包含具有内部细胞结构的柔性增塑的亲水性聚合物基质，和包含具有相对连续的内部结构的柔性增塑的亲水性聚合物基质的第二部分。第二部分可以与层部分相关联，使得第二部分在吸收层部分的主表面上渗透吸收层部分的一些但不是全部的细胞空隙。或者，第二部分可以与层部分相关联，使得第二部分覆盖在吸收层部分的主表面上。通过这种布置，一些但不是全部的吸收层部分被有效地暴露以吸收外部水或其它流体通过与吸收层的所述主面对应的片材的侧面。

3. 发明授权

US08871992B2 Multilayer compositions and dressings 有权
标题翻译：多层组合物和敷料
公开(公告)号：US08871992B2
公开(公告)日：2014-10-28
申请号：US13260669
申请日：2010-03-24
申请人： Hugh Semple Munro , Philip Andrews
发明人： Hugh Semple Munro , Philip Andrews
IPC分类号： A61F13/00
CPC分类号： A61F13/0203 , A61L15/60
摘要： The invention provides a layered composition comprising: a first layer comprising a first material, wherein the first material comprises a gel material; a second layer comprising a second material, wherein the second material is harder is than the first material; and a third layer comprising a third material, wherein the third material has a lower tensile modulus than the second material, wherein the second layer is disposed between the first and third layers. The composition may be used in a wound dressing, in which preferably the first layer is in fluid flow communication with the wound.
摘要翻译：本发明提供一种分层组合物，其包含：第一层，其包含第一材料，其中所述第一材料包含凝胶材料; 包括第二材料的第二层，其中所述第二材料比所述第一材料更硬; 以及包括第三材料的第三层，其中所述第三材料具有比所述第二材料低的拉伸模量，其中所述第二层设置在所述第一层和所述第三层之间。组合物可以用于伤口敷料中，其中优选地，第一层与伤口流体连通。

4. 发明授权

US08710289B2 Wound dressings 有权
标题翻译：伤口敷料
公开(公告)号：US08710289B2
公开(公告)日：2014-04-29
申请号：US13219385
申请日：2011-08-26
申请人： Malcolm Russell , Philip Andrews , Hugh Semple Munro , Robert Halstead , David Preece
发明人： Malcolm Russell , Philip Andrews , Hugh Semple Munro , Robert Halstead , David Preece
IPC分类号： A61F13/00
CPC分类号： A61F13/023 , A61F13/00068 , A61F13/0213 , A61F13/0226 , A61F13/0253 , A61F2013/00165
摘要： A dressing for covering a wound of a patient comprises a sheet member adapted to be adhered to the patient's skin in use to provide an airtight seal around the wound, wherein the skin-adhesion is provided by a hydrogel layer 10 on the skin-facing face of the sheet member, wherein the sheet member defines in use a substantially enclosed space 5 above the wound, and wherein a plurality of mutually spaced-apart flutter valves formed by holes 5 in a thin film 13 overlying an upper face of a layer 12 of the sheet member permit one-way air, blood and/or other fluid flow communication from the space 5 above the wound to the exterior of the dressing.
摘要翻译：用于覆盖患者的伤口的敷料包括适于在使用中粘附到患者皮肤上以提供围绕伤口的气密密封的片状构件，其中皮肤粘附由面向皮肤的面上的水凝胶层10提供其中所述片材构件在使用中限定在所述伤口上方的基本封闭的空间5，并且其中由薄膜13中的孔5形成的多个相互间隔开的颤动阀形成，所述薄膜13覆盖在层12的上部表面上片材允许从伤口上方的空间5到敷料外部的单向空气，血液和/或其它流体流动连通。

5. 发明申请

US20120078153A1 WOUND DRESSINGS 有权
标题翻译：连衣裙
公开(公告)号：US20120078153A1
公开(公告)日：2012-03-29
申请号：US13219385
申请日：2011-08-26
申请人： Malcolm Russell , Philip Andrews , Hugh Semple Munro , Robert Halstead , David Preece
发明人： Malcolm Russell , Philip Andrews , Hugh Semple Munro , Robert Halstead , David Preece
IPC分类号： A61F13/02
CPC分类号： A61F13/023 , A61F13/00068 , A61F13/0213 , A61F13/0226 , A61F13/0253 , A61F2013/00165
摘要： A dressing for covering a wound of a patient comprises a sheet member adapted to be adhered to the patient's skin in use to provide an airtight seal around the wound, wherein the skin-adhesion is provided by a hydrogel layer 10 on the skin-facing face of the sheet member, wherein the sheet member defines in use a substantially enclosed space 5 above the wound, and wherein a plurality of mutually spaced-apart flutter valves formed by holes 5 in a thin film 13 overlying an upper face of a layer 12 of the sheet member permit one-way air, blood and/or other fluid flow communication from the space 5 above the wound to the exterior of the dressing.
摘要翻译：用于覆盖患者的伤口的敷料包括适于在使用中粘附到患者皮肤上以提供围绕伤口的气密密封的片状构件，其中皮肤粘附由面向皮肤的面上的水凝胶层10提供其中所述片材构件在使用中限定在所述伤口上方的基本封闭的空间5，并且其中由薄膜13中的孔5形成的多个相互间隔开的颤动阀形成，所述薄膜13覆盖在层12的上部表面上片材允许从伤口上方的空间5到敷料外部的单向空气，血液和/或其它流体流动连通。

6. 发明申请

US20110190722A1 COMPOSITIONS FOR USE AS OR IN WOUND DRESSINGS 审中-公开
标题翻译：组合物用作或在连衣裙中使用
公开(公告)号：US20110190722A1
公开(公告)日：2011-08-04
申请号：US13054208
申请日：2009-07-16
申请人： Hugh Semple Munro , Philip Andrews
发明人： Hugh Semple Munro , Philip Andrews
IPC分类号： A61L15/22 , A61K9/00 , A61K9/70 , A61P17/02 , B01D15/04
CPC分类号： A61L15/60 , A61L15/425
摘要： The present invention provides a composition for the treatment of a wound, the composition comprising: a first layer, which comprises a porous, optionally hydrophilic material capable of absorbing fluid from the wound at least in part by capilliary action, a second layer comprising an absorbent hydrogel, the first layer being associated with the second layer, wherein, in the treatment, the first layer is disposed closer to the wound than the second layer and the composition modulates the concentration of dissolved ions in the fluid in the wound. The present invention further provides uses of the composition and methods of making the composition.
摘要翻译：本发明提供了一种用于治疗伤口的组合物，该组合物包括：第一层，其包含多孔的，任选亲水的材料，其能够至少部分地通过毛细作用从伤口吸收流体;第二层，包含吸收剂水凝胶，所述第一层与所述第二层相关联，其中在所述处理中，所述第一层设置成比所述第二层更靠近所述伤口，并且所述组合物调节所述伤口中流体中的溶解离子的浓度。本发明还提供组合物的用途和制备该组合物的方法。

7. 发明申请

US20110135726A1 HYDROGEL COMPOSITES AND WOUND DRESSINGS 审中-公开
标题翻译： HYDROGEL复合材料和连衣裙
公开(公告)号：US20110135726A1
公开(公告)日：2011-06-09
申请号：US12866611
申请日：2009-02-06
申请人： Hugh Semple Munro , Philip Andrews , Charles Jeffrey
发明人： Hugh Semple Munro , Philip Andrews , Charles Jeffrey
IPC分类号： A61K9/14 , A61P17/02
CPC分类号： A61L15/22 , A61L15/60
摘要： The present invention provides an absorbent hydrogel composite for use in the manufacture of an article for application to a fluid-emitting surface, e.g. a wound, the composite having a laminar structure comprising first and second layers, the first layer being a surface contacting layer comprising a porous net structure having a surface contacting face and an outwardly directed face, the second layer comprising a low-crosslinked absorbent hydrogel disposed over the outwardly directed face of the first layer and arranged so that in use it is in fluid flow communication with the surface through apertures of the net structure.
摘要翻译：本发明提供一种用于制造用于流体发射表面的制品的吸收性水凝胶复合材料，所述复合材料具有包括第一和第二层的层状结构，所述第一层是包括具有表面接触面和向外指向表面的多孔网结构的表面接触层，所述第二层包含低交联吸收性水凝胶在第一层的向外指向的表面上并且布置成使得在使用中它通过网状结构的孔与表面流体连通。

8. 发明申请

US20060148352A1 Absorbent materials and articles 审中-公开
标题翻译：吸收材料和制品
公开(公告)号：US20060148352A1
公开(公告)日：2006-07-06
申请号：US11256183
申请日：2005-10-24
申请人： Hugh Munro , Philip Andrews , Susana Garcia
发明人： Hugh Munro , Philip Andrews , Susana Garcia
IPC分类号： B32B5/24 , B32B27/12 , D03D9/00 , B32B5/26
CPC分类号： A61L15/60 , Y10T442/15 , Y10T442/159 , Y10T442/164 , Y10T442/183 , Y10T442/2484 , Y10T442/2508 , Y10T442/2525
摘要： An absorbent material comprises a flexible, skin-conformable, moisture-absorbent sheet member, optionally a net member in sheet form overlying and associated with the absorbent sheet member on at least one face thereof, and a hydrogel disposed on at least one of the net member, when present, and the absorbent sheet member in an amount of less than about 500 g of hydrogel per square metre per face, wherein the aqueous saline absorbency rate of the absorbent material through the face on which the hydrogel is disposed is less than about 300 seconds. Absorbent articles comprising the absorbent material and methods of manufacturing the material or articles are also described.
摘要翻译：一种吸收性材料包括柔性的，适合皮肤的吸湿性片材构件，任选的在片材形式的网状构件，其在至少一个表面上覆盖并与吸收性片材构件相关联，以及水凝胶，其设置在至少一个网并且吸收性片材的用量小于约500g每平方米每面的水凝胶，其中通过其上设置水凝胶的面的吸收材料的盐水吸收率低于约 300秒还描述了包含吸收材料的吸收制品和制造材料或制品的方法。

9. 发明申请

US20120116279A1 MULTILAYER COMPOSITIONS AND DRESSINGS 有权
标题翻译：多层组合物和连衣裙
公开(公告)号：US20120116279A1
公开(公告)日：2012-05-10
申请号：US13260669
申请日：2010-03-24
申请人： Hugh Semple Munro , Philip Andrews
发明人： Hugh Semple Munro , Philip Andrews
IPC分类号： A61F13/00 , B32B37/14 , B32B37/12
CPC分类号： A61F13/0203 , A61L15/60
摘要： The invention provides a layered composition comprising: a first layer comprising a first material, wherein the first material comprises a gel material; a second layer comprising a second material, wherein the second material is harder is than the first material; and a third layer comprising a third material, wherein the third material has a lower tensile modulus than the second material, wherein the second layer is disposed between the first and third layers. The composition may be used in a wound dressing, in which preferably the first layer is in fluid flow communication with the wound.
摘要翻译：本发明提供一种分层组合物，其包含：第一层，其包含第一材料，其中所述第一材料包含凝胶材料; 包括第二材料的第二层，其中所述第二材料比所述第一材料更硬; 以及包括第三材料的第三层，其中所述第三材料具有比所述第二材料低的拉伸模量，其中所述第二层设置在所述第一层和所述第三层之间。组合物可以用于伤口敷料中，其中优选地，第一层与伤口流体连通。

10. 发明申请

US20050287191A1 Hydrogel composites 审中-公开
标题翻译：水凝胶复合材料
公开(公告)号：US20050287191A1
公开(公告)日：2005-12-29
申请号：US11146276
申请日：2005-06-07
申请人： Hugh Munro , Philip Andrews , Gareth Jeffrey , Susana Sainz Garcia
发明人： Hugh Munro , Philip Andrews , Gareth Jeffrey , Susana Sainz Garcia
IPC分类号： C08F2/44 , A61K9/70
CPC分类号： C08F2/44 , Y10T442/2566
摘要： A method for producing a hydrogel/fibre composite comprises: impregnating fibres of a fibrous material with a precursor solution comprising at least one polymerisable, and optionally also crosslinkable, monomer such that at least partial swelling of the fibres takes place; and polymerising, and optionally also crosslinking, the at least one monomer after impregnation and at least partial swelling of the fibres such that the integrity of the fibrous material is at least partially preserved in the resulting hydrogel/fibre composite, provided that the crosslinking is not initiated solely by cation release from the fibres of the fibrous material. The invention provides a hydrogel/fibre composite prepared or preparable by the said method. The hydrogel/fibre composite may be adhesive to human skin with good properties of performance and subsequent painless removal. The composite is found to maintain acceptable strength and structural integrity on hydration or across one or more hydration/dehydration cycle, and thus finds use in, for example, biomedical products where this property is required.
摘要翻译：制备水凝胶/纤维复合材料的方法包括：用包含至少一种可聚合和任选地可交联的单体的前体溶液浸渍纤维材料的纤维，使得发生纤维的至少部分溶胀; 并且在浸渍之后聚合和任选地还交联至少一种单体，并且纤维的至少部分溶胀，使得纤维材料的完整性至少部分地保留在所得水凝胶/纤维复合材料中，条件是交联不是仅由纤维材料纤维的阳离子释放引发。本发明提供了通过所述方法制备或制备的水凝胶/纤维复合材料。水凝胶/纤维复合材料可以具有良好的性能性能和随后的无痛去除对人体皮肤的粘合性。发现复合材料在水合或一个或多个水化/脱水循环中保持可接受的强度和结构完整性，因此可用于例如需要该性质的生物医学产品。

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