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1. 发明申请

US20100083393A1 METHOD OF CONSTRUCTING CLONE MAMMAL 审中-公开
标题翻译：构建克隆动物的方法
公开(公告)号：US20100083393A1
公开(公告)日：2010-04-01
申请号：US11573995
申请日：2005-08-01
申请人： Hiroshi Wakao , Akihiko Koseki , Masaru Taniguchi , Atsuo Ogura , Kimiko Inoue
发明人： Hiroshi Wakao , Akihiko Koseki , Masaru Taniguchi , Atsuo Ogura , Kimiko Inoue
IPC分类号： A01K67/00 , C12N5/071 , A61K45/00 , A61P43/00
CPC分类号： C07K16/2809 , A01K67/0273 , C12N5/0606 , C12N15/8775 , C12N2517/02 , C12N2517/04 , C12N2517/10
摘要： The present invention provides a method of producing a cloned mammal, which uses a mammalian natural killer T cell as a donor cell, a cloned mammal obtained by the method, a method of obtaining an ES cell from the embryo of the cloned animal and an ES cell obtained by the method.
摘要翻译：本发明提供了使用哺乳动物天然杀伤T细胞作为供体细胞的克隆哺乳动物的制备方法，通过该方法获得的克隆哺乳动物，从克隆动物的胚胎获得ES细胞的方法和ES 通过该方法获得的细胞。

2. 发明申请

US20110020932A1 IN VITRO DIFFERENTIATION/INDUCTION OF LYMPHOCYTE FROM STEM CELL HAVING GENOTYPE PROVIDED AFTER GENE RECONSTITUTION 审中-公开
标题翻译：在具有基因组重组后提供的基因组的干细胞中进行体外分化/诱导淋巴细胞
公开(公告)号：US20110020932A1
公开(公告)日：2011-01-27
申请号：US12442887
申请日：2007-09-21
申请人： Hiroshi Wakao , Shin-ichiro Fujii , Kanako Shimizu , Haruhiko Koseki , Masaru Taniguchi , Atsuo Ogura , Hiroshi Kawamoto
发明人： Hiroshi Wakao , Shin-ichiro Fujii , Kanako Shimizu , Haruhiko Koseki , Masaru Taniguchi , Atsuo Ogura , Hiroshi Kawamoto
IPC分类号： C12N5/10
CPC分类号： C12N5/0646 , C12N2501/23 , C12N2501/42 , C12N2502/1394 , C12N2502/99 , C12N2506/02 , C12N2517/04
摘要： The present invention provides a production method of a functional differentiated cell having a post-rearrangement genotype of a particular antigen receptor gene, which includes culturing a stem cell having the genotype in a medium to give the differentiated cell derived from the stem cell. As the stem cell having the genotype, a stem cell (e.g., ES cell) established by transplantation of the nucleus of a cell having the genotype is preferable. As the differentiated cell, NKT cell is preferable.
摘要翻译：本发明提供了具有特定抗原受体基因的重排后基因型的功能性分化细胞的制备方法，其包括在培养基中培养具有基因型的干细胞，得到源自干细胞的分化细胞。作为具有基因型的干细胞，优选通过移植具有基因型的细胞的细胞核建立的干细胞（例如ES细胞）。作为分化细胞，优选NKT细胞。

3. 发明授权

US5477615A Sharp cutter 失效
标题翻译：锋利切割机
公开(公告)号：US5477615A
公开(公告)日：1995-12-26
申请号：US991183
申请日：1992-12-15
申请人： Hiroshi Wakao
发明人： Hiroshi Wakao
IPC分类号： B26B5/00 , B26B9/00
CPC分类号： B26B5/00
摘要： A cutter includes a container having openings at the top and at the bottom, and a removable cap that fits frictionally over the top opening. Inside the container is a plurality of units, each unit including a capsule with a blade member fixedly joined to and projecting from the capsule. These units fit frictionally atop one another in a nesting relationship inside the container with the blade member of one unit being received within a hollow opening in another unit.
摘要翻译：切割器包括在顶部和底部具有开口的容器以及摩擦地配合在顶部开口上的可拆卸盖。在容器内部是多个单元，每个单元包括具有固定地连接到胶囊并从胶囊突出的叶片构件的胶囊。这些单元在容器内以嵌套关系彼此摩擦地配合，一个单元的叶片构件被容纳在另一单元中的中空开口内。

4. 发明授权

US5299341A Rotating keyboard cleaner 失效
标题翻译：旋转键盘清洁剂
公开(公告)号：US5299341A
公开(公告)日：1994-04-05
申请号：US991863
申请日：1992-12-15
申请人： Hiroshi Wakao
发明人： Hiroshi Wakao
IPC分类号： A47L25/00
CPC分类号： A47L25/00
摘要： A rotating keyboard cleaner includes a container having openings at the top and at the bottom, and a removable cap that fits frictionally over the top opening. Inside the container is a plurality of units, each unit including a capsule with a cleaning head member fixedly joined to and projecting from the capsule. These units fit frictionally atop one another in a nesting relationship inside the container with the cleaning head member of one unit being received within a hollow opening in another unit.
摘要翻译：旋转式键盘清洁器包括在顶部和底部具有开口的容器，以及可滑动地盖住顶部开口。在容器内部是多个单元，每个单元包括具有固定地连接到胶囊并从胶囊突出的清洁头部件的胶囊。这些单元在容器内以嵌套关系彼此摩擦地配合，一个单元的清洁头部件被容纳在另一个单元中的中空开口内。

5. 发明授权

US5534409A Cytokine regulated transcription factor 失效
标题翻译：细胞因子调节转录因子
公开(公告)号：US5534409A
公开(公告)日：1996-07-09
申请号：US366276
申请日：1994-12-29
申请人： Bernd Groner , Fabrice Gouilleux , Hiroshi Wakao
发明人： Bernd Groner , Fabrice Gouilleux , Hiroshi Wakao
IPC分类号： C07K14/47 , C12Q1/68 , C07H21/02 , C07H21/04 , C12P19/34
CPC分类号： C07K14/4702
摘要： The present invention discloses isolated nucleic acids encoding MGF and recombinant proteins encoded thereby. In addition to being useful for the production of recombinant MGF, these nucleic acids are also useful as probes. In a further aspect of the invention, transfected host cells, particularly eukaryotic cells, containing and expressing such nucleic acids are provided. Furthermore, the present invention relates to methods for using such MGF proteins to identify and characterize compounds which affect the intracellular signal transduction of a lactogenic hormone.
摘要翻译：本发明公开了分离的编码MGF的核酸和由此编码的重组蛋白。除了可用于生产重组MGF之外，这些核酸还可用作探针。在本发明的另一方面，提供了含有和表达该核酸的转染宿主细胞，特别是真核细胞。此外，本发明涉及使用这样的MGF蛋白来鉴定和表征影响产生泌激素的细胞内信号转导的化合物的方法。

6. 发明授权

US5388698A Pocket carrier for dispensing products in precise quantitites 失效
标题翻译：用于以精确定量分配产品的袖珍载体
公开(公告)号：US5388698A
公开(公告)日：1995-02-14
申请号：US3296
申请日：1993-01-12
申请人： Hiroshi Wakao
发明人： Hiroshi Wakao
IPC分类号： A61J7/00 , B65D83/04 , B65G59/00
CPC分类号： B65D83/0409 , A61J7/0076 , B65D2583/0431 , B65D2583/045
摘要： A carrier/dispenser includes an outer container having openings at the top and at the bottom, and a removable cap that fits frictionally over the top opening. Inside the container is a plurality of units, each unit including a capsule that nests or interfits frictionally atop the other capsules inside the container. Each of the capsules is adapted to receive and hold a discrete, precise quantity of a desired powdered or solid substance such as a pill or tablet.
摘要翻译：载体/分配器包括在顶部和底部具有开口的外部容器以及摩擦地配合在顶部开口上的可拆卸盖。在容器内部是多个单元，每个单元包括在容器内的其它胶囊的顶部嵌套或摩擦的胶囊。每个胶囊适于接收和保持不连续的精确量的所需的粉末状或固体物质例如丸剂或片剂。

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