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    • 3. 发明授权
    • Radicicol derivatives
    • 蓝霉素衍生物
    • US06316491B1
    • 2001-11-13
    • US09091752
    • 1998-06-24
    • Yoji InoNobuyoshi AmishiroMayumi MiyataChikara MurakataHarumi OgawaTadakazu AkiyamaShiro AkinagaShiro SogaYukimasa Shiotsu
    • Yoji InoNobuyoshi AmishiroMayumi MiyataChikara MurakataHarumi OgawaTadakazu AkiyamaShiro AkinagaShiro SogaYukimasa Shiotsu
    • A61K3135
    • C07D493/04C07D313/00
    • Radioicol derivatives represented by the following formula (I) having tyrosine kinase inhibition activity or pharmacologically acceptable salts thereof: wherein R1 and R2 are the same or different, and each represents hydrogen, alkanoyl, alkenoyl, tert-butyldiphenylsilyl or tert-butyldimethylsilyl; R3 represents Y—R5 (wherein Y represents substituted or unsubstituted alkylene; and R5 represents CONR6R7 (wherein R6 represents hydrogen, hydroxyl, substituted or unsubstituted lower alkyl, substituted or unsubstituted higher alkyl, and the like; R7 represents hydroxyl, substituted lower alkyl, and the like), CO2R12 (wherein R12 represents substituted lower alkyl, substituted or unsubstituted higher alkyl, and the like), and the like) and the like; X represents halogen or is combined together with R4 to represent a single bond; and R4 is combined together with X to represent a single bond, or represents hydrogen, alkanoyl, and the like.
    • 由具有酪氨酸激酶抑制活性的下式(I)表示的放射性标记衍生物或其药理学上可接受的盐:其中R1和R2相同或不同,并且各自表示氢,烷酰基,烯酰基,叔丁基二苯基甲硅烷基或叔丁基二甲基甲硅烷基; R3表示Y-R5(其中Y表示取代或未取代的亚烷基; R5表示CONR6R7(其中R6表示氢,羟基,取代或未取代的低级烷基,取代或未取代的高级烷基等; R7表示羟基,取代的低级烷基, 等),CO 2 R 12(其中R 12表示取代的低级烷基,取代或未取代的高级烷基等)等)等; X表示卤素或与R 4一起表示单键; 并且R 4与X结合以表示单键,或表示氢,烷酰基等。
    • 8. 发明授权
    • Radicicol derivatives
    • 蓝霉素衍生物
    • US06635662B2
    • 2003-10-21
    • US09791602
    • 2001-02-26
    • Yoji InoNobuyoshi AmishiroMayumi MiyataChikara MurakataHarumi OgawaTadakazu AkiyamaShiro AkinagaShiro SogaYukimasa Shiotsu
    • Yoji InoNobuyoshi AmishiroMayumi MiyataChikara MurakataHarumi OgawaTadakazu AkiyamaShiro AkinagaShiro SogaYukimasa Shiotsu
    • A61K3144
    • C07D493/04C07D313/00
    • Radicicol derivatives represented by the following formula (I) having tyrosine kinase inhibition activity or pharmacologically acceptable salts thereof: wherein R1 and R2 are the same or different, and each represents hydrogen, alkanoyl, alkenoyl, tert-butyldiphenylsilyl or tert-butyldimethylsilyl; R3 represents Y—R5 {wherein Y represents substituted or unsubstituted alkylene; and R5 represents CONR5R7 (wherein R6 represents hydrogen, hydroxyl, substituted or unsubstituted lower alkyl, substituted or unsubstituted higher alkyl, and the like; R7 represents hydroxyl, substituted lower alkyl, and the like), CO2R12 (wherein R12 represents substituted lower alkyl, substituted or unsubstituted higher alkyl, and the like), and the like} and the like; X represents halogen or is combined together with R4 to represent a single bond; and R4 is combined together with X to represent a single bond, or represents hydrogen, alkanoyl, and the like.
    • 由下式(I)表示的具有酪氨酸激酶抑制活性的衍生物衍生物或其药理学上可接受的盐:其中R 1和R 2相同或不同,各自表示氢,链烷酰基,烯酰基,叔丁基二苯基甲硅烷基或 叔丁基二甲基甲硅烷基; R 3表示Y-R 5 {其中Y表示取代或未取代的亚烷基; 并且R 5表示CONR 5 R 7(其中R 6表示氢,羟基,取代或未取代的低级烷基,取代或未取代的高级烷基等; R 7表示羟基,取代的低级 烷基等),CO 2 R 12(其中R 12表示取代的低级烷基,取代或未取代的高级烷基等)等}等; X表示卤素或与R 4结合以表示单键;并且R 4与X一起组合以表示单键,或表示氢,烷酰基等。
    • 9. 发明授权
    • Light emitting and receiving circuit, camera and optical device
    • 发光和接收电路,摄像机和光学设备
    • US06449437B1
    • 2002-09-10
    • US09593719
    • 2000-06-14
    • Harumi Ogawa
    • Harumi Ogawa
    • G03B702
    • G01J1/4214
    • A light emitting and receiving circuit 10 has a light emitting diode 14 with a p-n junction. The light emitting diode 14 is connected with a circuit using the light emitting diode as a light emitting element, and a circuit using the light emitting diode 14 as a light receiving element that measures the intensity of a light. A switching means 16 is connected to the light emitting diode 14, for switching an operating state between a light receiving state where a photoelectromotive force is generated in a direction of biasing the p-n junction when receiving a light and a light emitting state where a forward voltage is applied to the light emitting diode 14 to emit a light according to at least one control signal.
    • 发光和接收电路10具有带p-n结的发光二极管14。 发光二极管14使用发光二极管作为发光元件和使用发光二极管14作为测量光的强度的光接收元件的电路连接。 开关装置16连接到发光二极管14,用于在接收光时在偏置pn结的方向上产生光电动势的光接收状态和正向电压的发光状态之间切换操作状态 被施加到发光二极管14以根据至少一个控制信号发光。