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1. 发明授权

US5593861A Dog-mouse heterohybridoma and gene fragment coding for constant region of canine immunoglobulins 失效
标题翻译：犬小鼠异源杂交瘤和编码犬免疫球蛋白恒定区的基因片段
公开(公告)号：US5593861A
公开(公告)日：1997-01-14
申请号：US306520
申请日：1994-09-15
申请人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
发明人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
IPC分类号： A61K39/00 , C07K16/46 , C12N5/26 , C12N15/13 , C12N15/00 , C07H21/04 , C12P21/04 , C12P21/06
CPC分类号： C07K16/462 , A61K39/00 , C07K2317/24
摘要： A gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of canine immunoglobulin lambda chain; a gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of canine immunoglobulin kappa chain; a gene fragment which comprises a DNA sequence coding for the constant region of canine immunoglobulin gamma chain; a recombinant DNA molecule coding for an amino acid sequence of a mouse-dog chimeric antibody which comprises a gene fragment coding for an amino acid sequence of a variable region of a mouse immunoglobulin and a gene fragment coding for an amino acid sequence of a constant region of a canine immunoglobulin; a polypeptide of a mouse-dog chimeric antibody which is expressed from a cell transformed with an expression vector for cells wherein said recombinant DNA molecule cording for an amino acid sequence of the mouse-dog chimeric antibody is incorporated; a dog-mouse heterohybridoma which produces canine immunoglobulin; and a process for preparing a canine immunoglobulin gene.
摘要翻译：一种基因片段，其包含编码犬免疫球蛋白λ链的恒定区的氨基酸序列的DNA序列; 基因片段，其包含编码犬免疫球蛋白κ链恒定区的氨基酸序列的DNA序列; 包含编码犬免疫球蛋白γ链的恒定区的DNA序列的基因片段; 编码小鼠 - 狗嵌合抗体的氨基酸序列的重组DNA分子，其包含编码小鼠免疫球蛋白的可变区的氨基酸序列的基因片段和编码恒定区的氨基酸序列的基因片段的犬免疫球蛋白; 从用细胞表达载体转化的细胞中表达小鼠 - 狗嵌合抗体的多肽，其中并入所述针对小鼠 - 狗嵌合抗体的氨基酸序列的重组DNA分子; 产生犬免疫球蛋白的狗 - 小鼠异源杂交瘤; 以及制备犬免疫球蛋白基因的方法。

2. 发明授权

US5880274A Cat-mouse heterohybridoma and gene fragment coding for constant region of feline immunoglobulin 失效
标题翻译：猫鼠异种杂交瘤和编码猫免疫球蛋白恒定区的基因片段
公开(公告)号：US5880274A
公开(公告)日：1999-03-09
申请号：US559947
申请日：1995-11-17
申请人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
发明人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
IPC分类号： C07K16/00 , C07K16/08 , C07K16/46 , C12N5/20 , C12N5/26 , C12N15/13 , C12P21/08 , C07H21/04 , C12N5/00 , C12N15/00
CPC分类号： C12N5/166 , C07K16/00 , C07K16/081 , C07K16/462 , C07K2317/24 , C07K2319/00
摘要： A Gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of feline immunoglobulin .lambda. chain; a gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of feline immunoglobulin .kappa. chain; a gene fragment which comprises a DNA sequence coding for the constant region of feline immunoglobulin .gamma. chain; a recombinant DNA molecule coding for an amino acid sequence of a mouse-cat chimeric antibody which comprises a gene fragment coding for an amino acid sequence of a variable region of a mouse immunoglobulin and a gene fragment coding for an amino acid sequence of a constant region of a feline immunoglobulin wherein the latter gene fragment is linked to the 3' site of the former gene fragment; a polypeptide of a mouse-cat chimeric antibody which is expressed from a cell transformed with an expression vector for cells wherein said recombinant DNA molecule coding for an amino acid sequence of the mouse-cat chimeric antibody is incorporated; a cat-mouse heterohybridoma which produces feline immunoglobulin; and a process for preparing a feline immunoglobulin gene.
摘要翻译：一种基因片段，其包含编码猫免疫球蛋白λ链的恒定区的氨基酸序列的DNA序列; 一种基因片段，其包含编码猫免疫球蛋白κ链的恒定区的氨基酸序列的DNA序列; 包含编码猫免疫球蛋白γ链恒定区的DNA序列的基因片段; 编码小鼠-cat嵌合抗体的氨基酸序列的重组DNA分子，其包含编码小鼠免疫球蛋白的可变区的氨基酸序列的基因片段和编码恒定区的氨基酸序列的基因片段的猫免疫球蛋白，其中后一个基因片段连接到前一个基因片段的3'位点; 将从编码小鼠-cat嵌合抗体的氨基酸序列的所述重组DNA分子并入的细胞的表达载体转化的细胞中表达的小鼠-cat嵌合抗体的多肽; 产生猫免疫球蛋白的猫 - 鼠异种杂交瘤; 以及制备猫免疫球蛋白基因的方法。

3. 发明授权

US5852183A Dog-mouse heterohybridoma and gene fragment coding for constant region of canine immunoglobulins 失效
标题翻译：犬小鼠异源杂交瘤和编码犬免疫球蛋白恒定区的基因片段
公开(公告)号：US5852183A
公开(公告)日：1998-12-22
申请号：US646981
申请日：1996-05-08
申请人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
发明人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
IPC分类号： A61K39/00 , C07K16/46 , C12N5/26 , C12N15/13 , C07H2/04 , C07H21/02
CPC分类号： C07K16/462 , A61K39/00 , C07K2317/24
摘要： A gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of canine immunoglobulin lambda chain; a gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of canine immunoglobulin kappa chain; a gene fragment which comprises a DNA sequence coding for the constant region of canine immunoglobulin gamma chain; a recombinant DNA molecule coding for an amino acid sequence of a mouse-dog chimeric antibody which comprises a gene fragment coding for an amino acid sequence of a variable region of a mouse immunoglobulin and a gene fragment coding for an amino acid sequence of a constant region of a canine immunoglobulin wherein the latter gene fragment; a polypeptide of a mouse-dog chimeric antibody which is expressed from a cell transformed with an expression vector for cells wherein said recombinant DNA molecule cording for an amino acid sequence of the mouse-dog chimeric antibody is incorporated; a dog-mouse heterohybridoma which produces canine immunoglobulin; and a process for preparing a canine immunoglobulin gene.
摘要翻译：一种基因片段，其包含编码犬免疫球蛋白λ链的恒定区的氨基酸序列的DNA序列; 基因片段，其包含编码犬免疫球蛋白κ链恒定区的氨基酸序列的DNA序列; 包含编码犬免疫球蛋白γ链的恒定区的DNA序列的基因片段; 编码小鼠 - 狗嵌合抗体的氨基酸序列的重组DNA分子，其包含编码小鼠免疫球蛋白的可变区的氨基酸序列的基因片段和编码恒定区的氨基酸序列的基因片段的犬免疫球蛋白，其中后者基因片段; 从用细胞表达载体转化的细胞中表达小鼠 - 狗嵌合抗体的多肽，其中并入所述针对小鼠 - 狗嵌合抗体的氨基酸序列的重组DNA分子; 产生犬免疫球蛋白的狗 - 小鼠异源杂交瘤; 以及制备犬免疫球蛋白基因的方法。

4. 发明授权

US5504198A Cat-mouse heterohybridoma and gene fragment coding for constant region of feline immunoglobulin 失效
公开(公告)号：US5504198A
公开(公告)日：1996-04-02
申请号：US247486
申请日：1994-05-23
申请人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
发明人： Hiroaki Maeda , Yasuyuki Eda , Kazuhiko Kimachi , Yoichi Ono , Sachio Tokiyoshi
IPC分类号： C07K16/00 , C07K16/08 , C07K16/46 , C12N5/20 , C12N5/26 , C12N15/13 , C12P21/08 , C07H21/04
CPC分类号： C12N5/166 , C07K16/00 , C07K16/081 , C07K16/462 , C07K2317/24 , C07K2319/00
摘要： A Gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of feline immunoglobulin .lambda. chain; a gene fragment which comprises a DNA sequence coding for an amino acid sequence of a constant region of feline immunoglobulin .kappa. chain; a gene fragment which comprises a DNA sequence coding for the constant region of feline immunoglobulin .gamma. chain; a recombinant DNA molecule coding for an amino acid sequence of a mouse-cat chimeric antibody which comprises a gene fragment coding for an amino acid sequence of a variable region of a mouse immunoglobulin and a gene fragment coding for an amino acid sequence of a constant region of a feline immunoglobulin wherein the latter gene fragment is linked to the 3' site of the former gene fragment; a polypeptide of a mouse-cat chimeric antibody which is expressed from a cell transformed with an expression vector for cells wherein said recombinant DNA molecule coding for an amino acid sequence of the mouse-cat chimeric antibody is incorporated; a cat-mouse heterohybridoma which produces feline immunoglobulin; and a process for preparing a feline immunoglobulin gene.

5. 发明授权

US06437846B1 Liquid crystal display device and electronic device including same 失效
标题翻译：液晶显示装置及包括其的电子装置
公开(公告)号：US06437846B1
公开(公告)日：2002-08-20
申请号：US08786145
申请日：1997-01-21
申请人： Yoichi Ono , Akira Tsukahara , Shoji Hinata
发明人： Yoichi Ono , Akira Tsukahara , Shoji Hinata
IPC分类号： G02F11335
CPC分类号： G02F1/13452 , G02F1/133305
摘要： A liquid crystal display device comprising a flexible substrate of, for example, plastic film. At least one edge of a pair of polarizers (9, 10), which are arranged on the liquid crystal display is extended to the region of an electrode terminal (7) which is formed on a substrate (2). By increasing the mechanical strength of the electrode terminal (7) of the liquid crystal display, terminal electrode cracks caused by mechanical stress that increase during the manufacturing process and incorporation into electronic calculators can be decreased and further, a liquid crystal display with a decreased number of disconnections and high reliability can be realized.
摘要翻译：一种液晶显示装置，包括例如塑料膜的柔性基板。布置在液晶显示器上的一对偏振器（9,10）的至少一个边缘延伸到形成在基板（2）上的电极端子（7）的区域。通过提高液晶显示器的电极端子（7）的机械强度，可以减少在制造过程中增加并结合到电子计算器中的机械应力引起的端子电极裂纹，并且还可以减少数量减少的液晶显示器的断开和高可靠性。

6. 发明授权

US06352254B1 Paper sheet manipulating apparatus and paper sheet transaction apparatus 失效
标题翻译：纸张处理装置和纸张交易装置
公开(公告)号：US06352254B1
公开(公告)日：2002-03-05
申请号：US09384208
申请日：1999-08-27
申请人： Atsunori Kimura , Yoichi Ono , Hayato Minamishin , Yuji Tanaka , Seiichi Ohno , Hidekazu Hata , Hiroyuki Ueda , Isamu Esaki , Atsushi Uchida
发明人： Atsunori Kimura , Yoichi Ono , Hayato Minamishin , Yuji Tanaka , Seiichi Ohno , Hidekazu Hata , Hiroyuki Ueda , Isamu Esaki , Atsushi Uchida
IPC分类号： B65H344
CPC分类号： G07D11/0018 , B65H83/025 , G07D11/0003 , G07D11/0021 , G07D11/0081 , Y10S209/90
摘要： A paper sheet manipulating apparatus and a paper sheet transaction apparatus for manipulating paper sheets such as bills includes an inlet/outlet port allowing input and output of paper sheets and rotating between the paper sheets inlet position and the paper sheet feeding position; a separating means projected to the outlet port and drawn back to the draw-back position, distinguish, when projected, the paper sheets inputted to the inlet port and the paper sheets to be returned and accommodate the paper sheets into the outlet port; an accommodation section for accommodating the paper sheets; a temporary storing section for temporarily storing the paper sheets which should not be accommodated in the accommodation section or should not be exhausted and a plurality of cassettes for feeding and collecting the paper sheets in the accommodation section and for feeding and collecting the paper sheets in the outlet port, whereby a fault is little generated and manipulations can be continued at a high speed for a long period of time without any pause even if a fault is generated.
摘要翻译：用于操作诸如纸币的纸张的纸张处理装置和纸张交易装置包括允许纸张的输入和输出并在纸张进入位置和纸张进给位置之间旋转的入口/出口; 突出到出口并被拉回到拉回位置的分离装置，当投影时区分输入到入口的纸张和要返回的纸张并将纸张容纳在出口中; 用于容纳纸张的容纳部分; 用于临时存放不应容纳在容纳部分中或不应排出的纸张的临时存储部分和用于将纸张进给和收集在容纳部分中的多个盒子，并用于将纸张进给和收集出口端口，由此即使发生故障也很少产生故障，并且可以高速持续长时间的操作，而不会发生任何停顿。

7. 发明授权

US5610742A Liquid crystal display element, methods of producing and storing the same, and electronic equipment on which the same is mounted 失效
标题翻译：液晶显示元件，制造和存储液晶显示元件的方法和安装在其上的电子设备
公开(公告)号：US5610742A
公开(公告)日：1997-03-11
申请号：US321453
申请日：1994-10-11
申请人： Shoji Hinata , Yoichi Ono , Akira Tsukahara , Hiroyuki Hosogaya , Yoshikatsu Imazeki , Shinji Fujisawa , Yoko Furukawa
发明人： Shoji Hinata , Yoichi Ono , Akira Tsukahara , Hiroyuki Hosogaya , Yoshikatsu Imazeki , Shinji Fujisawa , Yoko Furukawa
IPC分类号： G02F1/13 , G02F1/1333 , G02F1/1339
CPC分类号： G02F1/1333 , G02F1/1339 , G02F1/133305 , G02F1/133308 , Y10S29/044 , Y10T29/49718 , Y10T29/49723
摘要： A liquid crystal display element utilizing flexible gas barrier films decreases poor display performance caused by bubble formation. This decrease is achieved by reducing the permeation of gas and water vapor from the gas barrier films into substrates by devising the structure of the element and the configuration in which the element is mounted. Specifically, edges of the substrates forming the liquid crystal display elements are sealed. Additionally, the gas and water vapor saturation solubilities of the liquid crystal material is controlled to improve resistance to bubble formation. The liquid crystal display elements can also be subjected to and/or stored in a reduced pressure. Electronic equipment incorporating liquid crystal display elements can include a guard plate having a minimum thickness and/or spacing from the display elements.
摘要翻译：使用柔性阻气膜的液晶显示元件降低了由气泡形成引起的显示性能差。通过设计元件的结构和安装元件的构造，可以减少气体和水蒸汽从气体阻挡膜渗透到基底中来实现这种降低。具体地，形成液晶显示元件的基板的边缘被密封。此外，控制液晶材料的气体和水蒸汽饱和溶解度以改善对气泡形成的抵抗力。液晶显示元件也可以在减压下进行和/或存储。包含液晶显示元件的电子设备可以包括具有与显示元件最小的厚度和/或间隔的防护板。

8. 发明授权

US5083445A Cryopump 失效
标题翻译： CRYOPUMP
公开(公告)号：US5083445A
公开(公告)日：1992-01-28
申请号：US466633
申请日：1990-01-17
申请人： Norihide Saho , Taisei Uede , Yoichi Ono , Hisanao Ogata , Takeo Nemoto
发明人： Norihide Saho , Taisei Uede , Yoichi Ono , Hisanao Ogata , Takeo Nemoto
IPC分类号： B01D8/00 , F04B37/08
CPC分类号： F04B37/08 , B01D8/00 , Y10S417/901
摘要： A cryopump for effecting a cooling operation by a freezing medium such as liquid helium. A plurality of radiation-heat shield plates for protecting cryopanels against an external heat radiation are provided in opposed relation to a gas inlet of the cryopump. Particularly, a plurality of groups of such radiation-heat shield plates are provided in such a manner that the radiation-heat shield plates of each group are arranged in a multi-stage manner in registry with one another in the direction of the depth of the cryopump and are disposed in parallel relation to one another. Each of the cryopanels is disposed adjacent to a rear surface of respective radiation-heat shield plates facing away from the gas inlet. With this construction, the gas molecules reflected by those radiation-heat shield plates and by a rear wall of the cryopump, are less liable to reach the gas inlet, and tend to be condensed at an increased rate on those cryopanels.

9. 发明授权

US06776853B2 Cleaning method and method for manufacturing liquid crystal device 失效
标题翻译：液晶显示装置的清洗方法及方法
公开(公告)号：US06776853B2
公开(公告)日：2004-08-17
申请号：US09899758
申请日：2001-07-05
申请人： Yoichi Ono , Shinji Hashikura
发明人： Yoichi Ono , Shinji Hashikura
IPC分类号： B08B304
CPC分类号： C11D11/0047 , C11D1/40 , C11D1/523 , C11D3/18 , C11D11/0064 , G02F2001/133302 , Y10S134/902
摘要： In a cleaning apparatus 500, as a pre-cleaning step, cleaning is performed in a first and a second backup cleaning bath 602 and 603 using a hydrocarbon-based cleaning liquid composed of a normal paraffin, such as normal nonane or normal decane, as a primary component and a surfactant such as a fatty acid alkanol amide or a fatty acid N-alkyl alkylene diamine, and as a post-cleaning step, immersion cleaning, shower cleaning, and vapor cleaning are performed in a cleaning bath 601 using a hydrocarbon-based cleaning liquid containing no surfactant.
摘要翻译：在清洁装置500中，作为预清洁步骤，使用由普通正烷烃或正癸烷等正构石蜡组成的烃类清洗液，在第一和第二备用清洗槽602和603中进行清洗，作为主要组分和表面活性剂如脂肪酸烷醇酰胺或脂肪酸N-烷基亚烷基二胺，并且作为后清洗步骤，浸渍清洗，淋浴清洗和蒸气清洁在使用烃的清洗浴601中进行不含表面活性剂的清洗液。

10. 发明授权

US5687465A Method of removing a bubble from a liquid crystal display element 失效
标题翻译：从液晶显示元件去除气泡的方法
公开(公告)号：US5687465A
公开(公告)日：1997-11-18
申请号：US438032
申请日：1995-05-08
申请人： Shoji Hinata , Yoichi Ono
发明人： Shoji Hinata , Yoichi Ono
IPC分类号： G02F1/13 , G02F1/1333 , G02F1/1339 , B29C73/00
CPC分类号： G02F1/1333 , G02F1/1339 , G02F1/133305 , G02F1/133308 , Y10S29/044 , Y10T29/49718 , Y10T29/49723
摘要： A liquid crystal display element utilizing flexible gas barrier films decreases poor display performance caused by bubble formation. This decrease is achieved by reducing the permeation of gas and water vapor from the gas barrier films into substrates by devising the structure of the element and the configuration in which the element is mounted. Specifically, edges of the substrates forming the liquid crystal display elements are sealed. Additionally, the gas and water vapor saturation solubilities of the liquid crystal material is controlled to improve resistance to bubble formation. The liquid crystal display elements can also be subjected to and/or stored in a reduced pressure. Electronic equipment incorporating liquid crystal display elements can include a guard plate having a minimum thickness and/or spacing from the display elements.
摘要翻译：使用柔性阻气膜的液晶显示元件降低了由气泡形成引起的显示性能差。通过设计元件的结构和安装元件的构造，可以减少气体和水蒸汽从气体阻挡膜渗透到基底中来实现这种降低。具体地，形成液晶显示元件的基板的边缘被密封。此外，控制液晶材料的气体和水蒸汽饱和溶解度以改善对气泡形成的抵抗力。液晶显示元件也可以在减压下进行和/或存储。包含液晶显示元件的电子设备可以包括具有与显示元件最小的厚度和/或间隔的防护板。

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