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1. 发明授权

US06334200B1 Testable integrated circuit, integrated circuit design-for-testability method, and computer-readable medium storing a program for implementing the design-for-testability method 失效
标题翻译：可测试的集成电路，用于可测试性的集成电路设计方法和存储用于实现可设计性测试方法的程序的计算机可读介质
公开(公告)号：US06334200B1
公开(公告)日：2001-12-25
申请号：US09203372
申请日：1998-12-02
申请人： Hideo Fujiwara , Toshimitsu Masuzawa , Satoshi Ohtake
发明人： Hideo Fujiwara , Toshimitsu Masuzawa , Satoshi Ohtake
IPC分类号： G01R3128
CPC分类号： G01R31/318392 , G01R31/318522
摘要： Apparatus for testing integrated circuits containing a controller or other sequential circuit at actual operating speed while minimizing the length of the test sequence and achieving high fault coverage are provided. The states of a state register are assumed controllable and observable, and a set of test patterns is obtained for a combinational circuit not containing said state register. An invalid-state generation logic circuit is added for generating invalid states, which are states contained in the generated test patterns but cannot be set by a normal transition from the reset state. A multiplexer is added for selecting the output of a next-state generation logic circuit or the invalid-state generation logic circuit for input to the state register based on a state transition mode selection signal. Signals corresponding to pseudo-primary outputs during test generation are made observable, and the multiplexer output signal is externally detectable as a state output signal.
摘要翻译：提供了用于在实际操作速度下测试包含控制器或其他顺序电路的集成电路的装置，同时最小化测试序列的长度并实现高故障覆盖。状态寄存器的状态是可控的和可观察的，并且对于不包含所述状态寄存器的组合电路获得一组测试图案。添加无效状态生成逻辑电路，用于生成无效状态，这些状态是生成的测试模式中包含的状态，但不能通过从复位状态的正常转换来设置。添加多路复用器，用于根据状态转换模式选择信号选择下一状态生成逻辑电路的输出或无效状态生成逻辑电路，以输入到状态寄存器。在测试生成期间对应于伪初级输出的信号是可观察的，并且多路复用器输出信号作为状态输出信号在外部可检测。

2. 发明授权

US06735730B1 Integrated circuit with design for testability and method for designing the same 失效
标题翻译：具有可测试性设计的集成电路及其设计方法
公开(公告)号：US06735730B1
公开(公告)日：2004-05-11
申请号：US09699478
申请日：2000-10-31
申请人： Hideo Fujiwara , Toshimitsu Masuzawa , Satoshi Ohtake
发明人： Hideo Fujiwara , Toshimitsu Masuzawa , Satoshi Ohtake
IPC分类号： G01R3128
CPC分类号： G01R31/3183 , G01R31/31724
摘要： A test controller 4 has a test plan generating unit 11 for generating a test plan of a data path 2 which is formed to have a fixed control testability in which a test plan constituted by three phases, that is, the propagation of a test vector to a data input, the execution of a test and the propagation of an output response is present for each test object module. Thus, an integrated circuit is capable of supplying a test plan as a time series of a control signal to a control input of a data path, shortening a test execution time and generating the test plan at the normal operation speed of the circuit, thereby carrying out a test at an actual operation speed and an integrated circuit designing method.
摘要翻译：测试控制器4具有测试计划生成单元11，用于生成数据路径2的测试计划，数据路径2形成为具有固定控制可测试性，其中由三个阶段构成的测试计划，即测试向量的传播到对于每个测试对象模块，存在数据输入，测试的执行和输出响应的传播。因此，集成电路能够将作为控制信号的时间序列的测试计划提供给数据路径的控制输入，缩短测试执行时间，并以电路的正常操作速度生成测试计划，从而携带以实际运行速度进行测试和集成电路设计方法。

3. 发明授权

US09072783B2 Highly dispersible powders, compositions and methods for preparation 有权
标题翻译：高分散性粉末，组合物和制备方法
公开(公告)号：US09072783B2
公开(公告)日：2015-07-07
申请号：US13988248
申请日：2010-11-18
申请人： Satoshi Ohtake , Atul Saxena , Vu Truong-Le
发明人： Satoshi Ohtake , Atul Saxena , Vu Truong-Le
IPC分类号： A61K47/18 , A61K9/16 , A61K33/24
CPC分类号： A61K47/183 , A61K9/1617 , A61K33/24
摘要： A method for the selection of pharmaceutically acceptable excipients that allow for the production of highly dispersible powders produced by spray drying.
摘要翻译：用于选择允许生产通过喷雾干燥生产的高度分散性粉末的药学上可接受的赋形剂的方法。

4. 发明申请

US20110243988A1 Methods and Compositions for Stabilization of a Virus Vaccine 审中-公开
标题翻译：用于稳定病毒疫苗的方法和组合物
公开(公告)号：US20110243988A1
公开(公告)日：2011-10-06
申请号：US12896165
申请日：2010-10-01
申请人： Satoshi Ohtake , Vu Truong-Le , Luisa Yee , Russell A. Martin , David Lechuga-Ballesteros
发明人： Satoshi Ohtake , Vu Truong-Le , Luisa Yee , Russell A. Martin , David Lechuga-Ballesteros
IPC分类号： A61K39/165 , A61K39/00 , A61K39/12 , A61K39/02 , A61K39/112 , A61K39/235 , A61K39/15 , A61P37/02
CPC分类号： A61K39/165 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1641 , A61K9/1658 , A61K39/0275 , A61K39/12 , A61K2039/522 , A61K2039/55505 , Y02A50/482 , Y02A50/484
摘要： This invention provides compositions and methods for stabilizing a live attenuated virus in dried formulations. In particular, compositions and methods of preparing a dried vaccine are provided that stabilize the viability of live vaccines such as measles and adenovirus at room temperature.
摘要翻译：本发明提供用于在干燥制剂中稳定活减毒病毒的组合物和方法。特别地，提供了制备干燥疫苗的组合物和方法，其在室温下稳定活疫苗如麻疹和腺病毒的活力。

5. 发明授权

US06633291B1 Method and apparatus for displaying an image 失效
标题翻译：用于显示图像的方法和装置
公开(公告)号：US06633291B1
公开(公告)日：2003-10-14
申请号：US09516208
申请日：2000-02-29
申请人： Hirofumi Sugitani , Yoshihito Tanaka , Masaaki Yoshikawa , Satoshi Ohtake , Noritsune Sekiguchi
发明人： Hirofumi Sugitani , Yoshihito Tanaka , Masaaki Yoshikawa , Satoshi Ohtake , Noritsune Sekiguchi
IPC分类号： G06T1510
CPC分类号： G06T15/10 , G06T17/00
摘要： A three-dimensional shape model indicating a first part is constructed and a three-dimensional shape that works as a transparent screen is disposed thereon continuously. A sight line direction is set and the three-dimensional shape model is displayed after rotated in accordance with the set sight line direction. A first two-dimensional image is constructed in accordance with the sight line direction, and a second two-dimensional image is constructed. The first two-dimensional image and the second two-dimensional image are combined with each other so as to construct a combined two-dimensional image. The combined two-dimensional image is assigned so that the part thereof corresponding to the first two-dimensional image agrees with the three-dimensional shape model, and the combined two-dimensional image is displayed visually.
摘要翻译：构成表示第一部分的三维形状模型，并且连续地设置作为透明屏幕的三维形状。设置视线方向，并且根据设定的视线方向旋转后显示三维形状模型。根据视线方向构造第一二维图像，构造第二二维图像。将第一二维图像和第二二维图像相互组合，以构成组合的二维图像。分配组合的二维图像，使得其对应于第一二维图像的部分与三维形状模型一致，并且组合的二维图像被目视显示。

6. 发明授权

US09539233B2 Gallium formulation for the treatment and prevention of infectious diseases 有权
标题翻译：用于治疗和预防传染病的镓制剂
公开(公告)号：US09539233B2
公开(公告)日：2017-01-10
申请号：US12772854
申请日：2010-05-03
申请人： Satoshi Ohtake , Vu Truong-Le , David Lechuga-Ballesteros , Luisa Yee , Binh Pham , Russell Martin , Atul Saxena
发明人： Satoshi Ohtake , Vu Truong-Le , David Lechuga-Ballesteros , Luisa Yee , Binh Pham , Russell Martin , Atul Saxena
IPC分类号： A01N59/16 , A61K33/24 , A61K31/28 , A61K9/00 , A61K9/08 , A61K9/14 , A61K9/16 , A61K47/12
CPC分类号： A61K31/28 , A61K9/0078 , A61K9/08 , A61K9/14 , A61K9/1617 , A61K9/1623 , A61K33/24 , A61K47/12 , Y02A50/473 , Y10T428/2982
摘要： A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as Staphylococcus aureus, Rhodococcus equi, Mycobacterium tuberculosis, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a formulation containing gallium (III), in a pharmaceutically acceptable salt or complex thereof.
摘要翻译：用于治疗由革兰氏阴性或革兰氏阳性细菌如金黄色葡萄球菌，马氏体球菌，结核分枝杆菌，大肠杆菌，肺炎克雷伯菌，克雷伯杆菌，铜绿假单胞菌，流感嗜血杆菌，奇异变形杆菌，肠杆菌属，沙雷氏菌属引起的细菌感染的方法和组合物粘膜结肠炎以及由伯克霍克伯克伯克霍尔德氏菌，嗜麦芽寡养单胞菌，产碱杆菌xylosoxidans和多药耐药铜绿假单胞菌引起的那些，其使用含有镓（III）的制剂在其药学上可接受的盐或复合物中。

7. 发明授权

US08673357B2 Sonic low pressure spray drying 有权
标题翻译：声波低压喷雾干燥
公开(公告)号：US08673357B2
公开(公告)日：2014-03-18
申请号：US13585096
申请日：2012-08-14
申请人： Vu Truong-Le , Satoshi Ohtake , Russell Andrew Martin , Binh V. Pham , Luisa Yee
发明人： Vu Truong-Le , Satoshi Ohtake , Russell Andrew Martin , Binh V. Pham , Luisa Yee
IPC分类号： A61K9/14 , F26B5/06
CPC分类号： B01D1/18
摘要： This invention provides methods of spray drying pharmaceutical powders from a vibrating nozzle at low pressures. The method can effectively spray dry thick or viscous solutions or suspensions to provide small uniform particles. The invention includes dry particle compositions prepared by methods of low pressure spraying from vibrating nozzles.
摘要翻译：本发明提供了在低压下从振动喷嘴喷雾干燥药物粉末的方法。该方法可以有效地喷洒干燥的稠粘或粘稠溶液或悬浮液以提供小的均匀颗粒。本发明包括通过从振动喷嘴进行低压喷射的方法制备的干燥颗粒组合物。

8. 发明授权

US08637090B2 Gallium formulation for the treatment and prevention of infectious diseases 有权
标题翻译：用于治疗和预防传染病的镓制剂
公开(公告)号：US08637090B2
公开(公告)日：2014-01-28
申请号：US13318774
申请日：2010-05-04
申请人： Satoshi Ohtake , Vu Truong-Le , David Lechuga-Ballesteros , Luisa Yee , Binh V Pham , Russell Martin , Atul Saxena
发明人： Satoshi Ohtake , Vu Truong-Le , David Lechuga-Ballesteros , Luisa Yee , Binh V Pham , Russell Martin , Atul Saxena
IPC分类号： A61K33/24
CPC分类号： A61K31/28 , A61K9/0078 , A61K9/08 , A61K9/14 , A61K9/1617 , A61K9/1623 , A61K33/24 , A61K47/12 , Y02A50/473 , Y10T428/2982
摘要： A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as Staphylococcus aureus, Rhodococcus equi, Mycobacterium tuberculosis, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a formulation containing gallium (III), in a pharmaceutically acceptable salt or complex thereof.
摘要翻译：用于治疗由革兰氏阴性或革兰氏阳性细菌如金黄色葡萄球菌，马氏体球菌，结核分枝杆菌，大肠杆菌，肺炎克雷伯菌，克雷伯杆菌，铜绿假单胞菌，流感嗜血杆菌，奇异变形杆菌，肠杆菌属，沙雷氏菌属引起的细菌感染的方法和组合物粘膜结肠炎以及由伯克霍克伯克伯克霍尔德氏菌，嗜麦芽寡养单胞菌，产碱杆菌xylosoxidans和多药耐药铜绿假单胞菌引起的那些，其使用含有镓（III）的制剂在其药学上可接受的盐或复合物中。

9. 发明申请

US20130302425A1 HIGHLY DISPERSIBLE POWDERS, COMPOSITIONS AND METHODS FOR PREPARATION 有权
标题翻译：高度分散的粉末，组合物和制备方法
公开(公告)号：US20130302425A1
公开(公告)日：2013-11-14
申请号：US13988248
申请日：2010-11-18
申请人： Satoshi Ohtake , Atul Saxena , Vu Truong-Le
发明人： Satoshi Ohtake , Atul Saxena , Vu Truong-Le
IPC分类号： A61K47/18 , A61K33/24
CPC分类号： A61K47/183 , A61K9/1617 , A61K33/24
摘要： A method for the selection of pharmaceutically acceptable excipients that allow for the production of highly dispersible powders produced by spray drying.
摘要翻译：用于选择允许生产通过喷雾干燥生产的高度分散性粉末的药学上可接受的赋形剂的方法。

10. 发明申请

US20120308526A1 Sonic Low Pressure Spray Drying 有权
标题翻译：声波低压喷雾干燥
公开(公告)号：US20120308526A1
公开(公告)日：2012-12-06
申请号：US13585096
申请日：2012-08-14
申请人： Satoshi Ohtake , Russell Andrew Martin , Binh Pham , Luisa Yee
发明人： Satoshi Ohtake , Russell Andrew Martin , Binh Pham , Luisa Yee
IPC分类号： B29B9/12 , A61K35/74 , A61K38/44 , A61K35/76
CPC分类号： B01D1/18
摘要： This invention provides methods of spray drying pharmaceutical powders from a vibrating nozzle at low pressures. The method can effectively spray dry thick or viscous solutions or suspensions to provide small uniform particles. The invention includes dry particle compositions prepared by methods of low pressure spraying from vibrating nozzles.
摘要翻译：本发明提供了在低压下从振动喷嘴喷雾干燥药物粉末的方法。该方法可以有效地喷洒干燥的稠粘或粘稠溶液或悬浮液以提供小的均匀颗粒。本发明包括通过从振动喷嘴进行低压喷射的方法制备的干燥颗粒组合物。

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