专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06412681B2 Soldering machine 有权
公开(公告)号：US06412681B2
公开(公告)日：2002-07-02
申请号：US09732939
申请日：2000-12-11
申请人： Hideki Mukuno , Kazumi Tashiro , Hideaki Arita , Kiyoshi Kanai , Teruo Okano , Fumihiro Yamashita , Shoichirou Matsuhisa , Hidekazu Imai
发明人： Hideki Mukuno , Kazumi Tashiro , Hideaki Arita , Kiyoshi Kanai , Teruo Okano , Fumihiro Yamashita , Shoichirou Matsuhisa , Hidekazu Imai
IPC分类号： B23K100
CPC分类号： B23K1/012 , B23K2101/42
摘要： A soldering machine using lead-free solders is provided which can uniformly heat a printed circuit board and electronic parts to be mounted thereon, and which can solder the electronic parts without thermally damaging them. A porous member having a number of holes formed therein is disposed between a blower fan and a heater for making uniform the pressure of a fluid. A radiation plate is disposed between the heater and a heating target for blowing the fluid having been heated by the heater to the heating target in the form of a turbulent flow. The heated fluid is blown to the heating target for heating the same, whereby solder is melted.

2. 发明授权

US06761301B2 Soldering machine 有权
标题翻译：焊机
公开(公告)号：US06761301B2
公开(公告)日：2004-07-13
申请号：US10097610
申请日：2002-03-15
申请人： Hideki Mukuno , Kazumi Tashiro , Hideaki Arita , Kiyoshi Kanai , Teruo Okano , Fumihiro Yamashita , Shoichirou Matsuhisa , Hidekazu Imai
发明人： Hideki Mukuno , Kazumi Tashiro , Hideaki Arita , Kiyoshi Kanai , Teruo Okano , Fumihiro Yamashita , Shoichirou Matsuhisa , Hidekazu Imai
IPC分类号： B23K100
CPC分类号： B23K1/012 , B23K2101/42
摘要： A soldering machine using lead-free solders is provided which can uniformly heat a printed circuit board and electronic parts to be mounted thereon, and which can solder the electronic parts without thermally damaging them. A porous member having a number of holes formed therein is disposed between a blower fan and a heater for making uniform the pressure of a fluid. A radiation plate is disposed between the heater and a heating target for blowing the fluid having been heated by the heater to the heating target in the form of a turbulent flow. The heated fluid is blown to the heating target for heating the same, whereby solder is melted.
摘要翻译：提供了一种使用无铅焊料的焊接机，其能够均匀地加热印刷电路板和要安装在其上的电子部件，并且可以焊接电子部件而不会对其造成热损害。在鼓风扇和加热器之间设置有多个孔的多孔构件，用于使流体的压力均匀。辐射板设置在加热器和加热靶之间，用于将被加热器加热的流体以湍流的形式吹送到加热靶。被加热的流体被吹送到加热对象以加热，从而焊料熔化。

3. 发明授权

US10603410B2 Complex of implant and cultured periodontal ligament cell sheet, method for manufacturing the same, and method for using the same 有权
公开(公告)号：US10603410B2
公开(公告)日：2020-03-31
申请号：US15321357
申请日：2015-06-24
申请人： Kaoru Washio , Isao Ishikawa , Teruo Okano , GNERAL INC.
发明人： Kaoru Washio , Isao Ishikawa , Teruo Okano , Takao Hanawa , Yusuke Tsutsumi , Yuka Tsumanuma , Supreda Suphanantachat , Kosei Yano
IPC分类号： A61L27/38 , A61L27/32 , A61C8/00 , A61L27/06 , A61L27/16 , A61L27/36 , A61C8/02
摘要： A complex of implant and cultured periodontal ligament cell sheet, that can be satisfactorily stabilized into the bone through periodontal ligament tissue, is provided. A fixture of the inserted implant is coated with calcium phosphate and the cultured periodontal ligament cell sheet is brought into intimate contact with the implant.

4. 发明授权

US09289454B2 Method for manufacturing multilayered cell sheet, multilayered cell sheet having vascular network obtained thereby, and method of use thereof 有权
标题翻译：制造多层细胞片的方法，由此获得的具有血管网的多层细胞片及其使用方法
公开(公告)号：US09289454B2
公开(公告)日：2016-03-22
申请号：US13822945
申请日：2011-09-14
申请人： Hidekazu Sekine , Tatsuya Shimizu , Teruo Okano
发明人： Hidekazu Sekine , Tatsuya Shimizu , Teruo Okano
IPC分类号： A61K35/44 , A61K35/34 , A61K35/36 , C12N5/077 , A61L27/36 , A61L27/38
CPC分类号： A61K35/44 , A61K35/34 , A61K35/36 , A61L27/3604 , A61L27/3839 , A61L27/3895 , C12N5/0657 , C12N2502/28 , C12N2513/00
摘要： A method for producing multilayered cell sheets, including producing a vascular bed which includes an artery-vein loop and in which a capillary vascular network is constructed; layering cell sheets on the vascular bed; and perfusing a culture medium in vitro to construct a vascular network in the cell sheets. The production method enables vascular networks to be constructed in cell sheets and enables thick multilayered cell sheets to foe easily produced by layering the cell sheets. Such thick multilayered cell sheets are useful as in vivo tissue-like products for regenerative medicine for various tissues and for evaluation of drugs and the like.
摘要翻译：一种生产多层细胞片的方法，包括制备包括动静脉环的血管床，其中构成毛细血管网络; 在血管床上分层细胞片; 并在体外灌注培养基以在细胞片中构建血管网络。该制造方法能够在细胞片中构建血管网络，能够通过层叠细胞片容易地制造厚层多层细胞片。这种厚的多层细胞片可用作用于各种组织的再生医学的体内组织样产品和药物等的评估。

5. 发明申请

US20140056859A1 METHOD FOR PRODUCING MYOCARDIAL SHEET FROM EMBRYONIC STEM CELLS 有权
标题翻译：用于从胚胎干细胞生产心肌细胞片的方法
公开(公告)号：US20140056859A1
公开(公告)日：2014-02-27
申请号：US14009018
申请日：2013-03-30
申请人： Teruo Okano , Tatsuya Shimizu , Jun Yamashita , Hidetoshi Masumoto
发明人： Teruo Okano , Tatsuya Shimizu , Jun Yamashita , Hidetoshi Masumoto
IPC分类号： A61K35/34 , A61K35/44 , A61K9/70
CPC分类号： A61K35/34 , A61K9/70 , A61K35/44 , A61L27/3834 , A61L27/3886 , A61L27/54 , A61L2300/414 , A61L2430/20 , C12N5/0657 , C12N5/0697 , C12N2501/01 , C12N2501/04 , C12N2501/165 , C12N2502/1329 , C12N2502/1347 , C12N2502/28 , C12N2506/02 , A61K2300/00
摘要： The present invention provides a method for producing a myocardial sheet using a group of cells derived from embryonic stem cells. This method is characterized by mixing Flk/KDR positive cells, cardiomyocytes, endothelial cells, and mural cells, all derived from embryonic stem cells, and culturing the mixed cells. Furthermore, the myocardial sheet can be used as a therapeutic agent for heart diseases since VEGF is released from the sheet.
摘要翻译：本发明提供使用源自胚胎干细胞的一组细胞产生心肌片的方法。该方法的特征在于混合来自胚胎干细胞的Flk / KDR阳性细胞，心肌细胞，内皮细胞和壁细胞，并培养混合细胞。此外，心肌片可用作心脏病的治疗剂，因为VEGF从片材中释放出来。

6. 发明授权

US08642338B2 Anterior ocular segment related cell sheets, three-dimensional structures, and processes for producing the same 有权
标题翻译：前眼部相关细胞片，三维结构及其制备方法
公开(公告)号：US08642338B2
公开(公告)日：2014-02-04
申请号：US10544542
申请日：2003-02-06
申请人： Masayuki Yamato , Teruo Okano
发明人： Masayuki Yamato , Teruo Okano
IPC分类号： C12N11/08 , C12N5/00 , C12N5/02
CPC分类号： C12N5/0621 , A61K35/12
摘要： An anterior ocular segment related cell sheet or three-dimensional structure that have only a few structural defects as they have been recovered retaining the intercellular desmosome structure and the basement membrane-like protein between cell and substrate. The anterior ocular segment related cell sheet or three-dimensional structure is produced by a process comprising the steps of cultivating cells on a cell culture support comprising a substrate having its surface covered with a temperature responsive polymer having an upper or lower critical dissolution temperature of 0-80° C. with respect to water, optionally stratifying the layer of cultured cells by the usual method, and thereafter, (1) adjusting the temperature of the culture solution to either above the upper critical dissolution temperature or below the lower critical dissolution temperature, and further optionally (2) bringing the cultured anterior ocular segment related cell sheet or three-dimensional structure into close contact with a polymer membrane, and (3) detaching the sheet or three-dimensional structure together with the polymer membrane.
摘要翻译：前眼部相关的细胞片或三维结构只有几个结构缺陷，因为它们已经被回收，保留了细胞和基质之间的细胞间质结构和基底膜样蛋白。前眼部相关细胞片或三维结构的制备方法包括以下步骤：在细胞培养支持物上培养细胞，所述细胞培养载体包含其表面被温度响应性聚合物覆盖的基底，所述温度响应聚合物具有上或下临界溶解温度为0 -80℃，任选地通过常规方法分层培养细胞层，然后，（1）将培养溶液的温度调节至高于上临界溶解温度或低于临界溶解温度，进一步任选地（2）使培养的眼前段相关细胞片或三维结构与聚合物膜紧密接触，和（3）与聚合物膜一起分离片或三维结构。

7. 发明申请

US20130289723A1 MIDDLE EAR MUCOSA-LIKE CELL SHEET, PROCESS OF PRODUCING THE SAME AND METHOD OF USING THE SAME 审中-公开
标题翻译：中等耳状细胞片及其制造方法及其使用方法
公开(公告)号：US20130289723A1
公开(公告)日：2013-10-31
申请号：US13823240
申请日：2011-09-15
申请人： Takanori Hama , Hiromi Kojima , Hiroshi Moriyama , Masayuki Yamato , Teruo Okano
发明人： Takanori Hama , Hiromi Kojima , Hiroshi Moriyama , Masayuki Yamato , Teruo Okano
IPC分类号： A61F2/18
CPC分类号： A61F2/18 , A61F2002/183 , A61F2310/00365 , A61K35/12 , A61L27/3804 , A61L27/3813 , A61L27/3839 , A61L27/3886 , A61L2430/14 , C12N5/062 , C12N2533/30
摘要： The purpose of the present invention is to obtain an alternative to a substitute of the mucosa in the middle ear which is engrafted on the surface of the bone in the middle ear, hyperplasia of the granulation tissue and the bone and the development of the fibroblast cell sir the middle ear are suppressed, and to obtain a middle ear mucosa-like cell sheet retaining cilia in the surface layer, comprising culturing nasal epithelium cells on a cell culture substrate coated with a polymer whose hydration force changes within a temperature range of 0 to 80 ° C., wherein the cells are cultured within a temperature range where the hydration force of the polymer is weak, and then changing the temperature to a temperature at which the hydration force is strong to recover the cultured cell sheet.
摘要翻译：本发明的目的是获得中耳粘膜替代物，其置于中耳骨表面上，肉芽组织和骨骼的增生以及成纤维细胞的发育中耳的中耳被抑制，并获得在表层中保留纤毛的中耳粘膜样细胞片，包括在涂覆有聚合物的细胞培养基质上培养鼻上皮细胞，其水合力在0至 80℃，其中在聚合物的水合力弱的温度范围内培养细胞，然后将温度改变到水合力强的温度以回收培养的细胞片。

8. 发明申请

US20120214250A1 METHOD AND APPARATUS FOR MEASURING PH OF SOLUTION 有权
标题翻译：用于测量溶液PH值的方法和装置
公开(公告)号：US20120214250A1
公开(公告)日：2012-08-23
申请号：US13400106
申请日：2012-02-19
申请人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
发明人： Mitsuhiro Oura , Teruo Okano , Tatsuya Shimizu , Hirotsugu Kubo , Sunao Takeda , Shinji Yamamori
IPC分类号： G01N21/59
CPC分类号： G01N21/80 , C12M41/26 , G01N21/3151 , G01N31/221 , G01N2201/0627 , G01N2201/1211
摘要： A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances ; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.
摘要翻译：测量溶液的pH的方法包括：在测量区域中的溶液脉动的同时，从混合有指示剂的溶液的测量区域的一侧发射两个波长的光束; 在所述测量区域中的所述溶液脉动的同时，在测量区域的另一侧上接收发射光束的透射光束和反射光束中的至少一个; 基于所接收的所述透射光束和所述反射光束中的至少一个，获得所述两个波长的吸光度; 从所获得的吸光度获得吸光度比; 并且基于所获得的吸光度比和预先存储的吸光度比/ pH值对应数据库来计算溶液的pH值。

9. 发明申请

US20110207220A1 CELL PATTERN RECOVERY TOOL 有权
标题翻译：细胞图案恢复工具
公开(公告)号：US20110207220A1
公开(公告)日：2011-08-25
申请号：US13125491
申请日：2009-08-11
申请人： Teruo Okano , Masayuki Yamato , Tatsuya Shimizu , Masatoshi Kuroda
发明人： Teruo Okano , Masayuki Yamato , Tatsuya Shimizu , Masatoshi Kuroda
IPC分类号： C12N5/071
CPC分类号： C12N11/02 , C12M23/20 , C12M33/00 , C12N5/0062 , C12N2535/10 , C12N2539/10
摘要： This invention provides a cell pattern recovery tool comprising a base material layer having a surface subjected to easy adhesion treatment, a temperature responsive polymer layer that is provided on the base material layer and has a surface subjected to silane treatment, and a cell adhesion inhibiting material layer provided on the temperature responsive polymer layer. According to the present invention, a cell pattern can be rapidly recovered while maintaining the cell pattern stably and reliably under minimally invasive conditions for the cells.
摘要翻译：本发明提供了一种电池图案回收工具，其包括具有易于粘附处理的表面的基材层，设置在基材层上并具有进行硅烷处理的表面的温度响应性聚合物层和细胞粘附抑制材料提供在温度敏感聚合物层上的层。根据本发明，可以在针对细胞的微创条件下稳定且可靠地保持细胞图案，能够快速地恢复细胞图案。

10. 发明授权

US07470424B2 Cultured cell construct containing spheroids of cultured animal cells and utilization thereof 有权
标题翻译：含培养动物细胞球状体的培养细胞构建体及其应用
公开(公告)号：US07470424B2
公开(公告)日：2008-12-30
申请号：US10484839
申请日：2002-07-25
申请人： Kazunori Kataoka , Hidenori Otsuka , Teruo Okano , Yukio Nagasaki , Yasuhiro Horiike
发明人： Kazunori Kataoka , Hidenori Otsuka , Teruo Okano , Yukio Nagasaki , Yasuhiro Horiike
IPC分类号： C12N5/02 , C12N5/06
CPC分类号： C12N5/0671 , C12N5/0697 , C12N2502/14 , C12N2502/28 , C12N2533/30 , C12N2533/40 , C12N2535/10
摘要： Parenchymal cells are cultivated on cultivated endothelial cells or cultivated fibroblasts which have been separated by a surface of a specific hydrophilic polymer, and which have been patterned. A culture which contains thus formed patterned spheroids of cultivated parenchymal cells is thereby provided by this invention. This culture maintains a function which is specific to the parenchymal cells over a long period of time.
摘要翻译：将实质细胞培养在培养的内皮细胞或培养的成纤维细胞上，这些成纤维细胞已经被特定的亲水性聚合物的表面分离并且已被图案化。因此本发明提供了含有如此形成的培养实质细胞的图案化球体的培养物。该培养物保持长时间对实质细胞特异的功能。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式