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1. 发明授权

US06233483B1 System and method for generating a high efficiency biphasic defibrillation waveform for use in an implantable cardioverter/defibrillator (ICD). 失效
标题翻译：用于产生用于可植入式心律转复除颤器（ICD）的高效双相除颤波形的系统和方法。
公开(公告)号：US06233483B1
公开(公告)日：2001-05-15
申请号：US09073394
申请日：1998-05-05
申请人： James D. Causey, III , Gabriel Mouchawar , Herman L. Renger , Mark W. Kroll
发明人： James D. Causey, III , Gabriel Mouchawar , Herman L. Renger , Mark W. Kroll
IPC分类号： A61N139
CPC分类号： A61N1/3906 , A61N1/3912 , A61N1/3956
摘要： In an ICD, a highly efficient biphasic defibrillation pulse is generated by switching at least two charged capacitors, e.g., three capacitors, from a parallel connection to various combinations of a parallel/series connection or a series connection during the first phase of the defibrillation pulse. Such mid-stream parallel/series connection changes of the capacitors steps up the voltage applied to the cardiac tissue during the first phase. A stepped-up voltage during the first phase, in turn, gives an extra boost to, and thereby forces additional charge (current) into, the cardiac tissue cells, and thereby transfers more charge to the membrane of the excitable cardiac cell than if the capacitors were continuously discharged in series. Phase reversal is timed with the cell membrane reaching its maximum value at the end of the first phase.
摘要翻译：在ICD中，通过在除颤脉冲的第一阶段期间将至少两个带电电容器（例如三个电容器）从并联连接切换到并联/串联或串联连接的各种组合来产生高效双相除颤脉冲。电容器的这种中流并联/串联连接变化在第一阶段期间增加施加到心脏组织的电压。第一阶段期间的升高电压反过来又给予心脏组织细胞额外的增加，从而迫使额外的电荷（电流）进入心脏组织细胞，从而将更多的电荷转移到可兴奋的心脏细胞的膜上，如果电容器串联连续放电。在第一阶段结束时，细胞膜达到其最大值时，反相相反。

2. 发明授权

US4814685A Inductive power converter for use with variable input and output voltages 失效
标题翻译：用于可变输入和输出电压的感应功率转换器
公开(公告)号：US4814685A
公开(公告)日：1989-03-21
申请号：US128977
申请日：1987-12-04
申请人： Herman L. Renger
发明人： Herman L. Renger
IPC分类号： G01R19/165 , H02M3/00 , H02M3/155 , H02M3/158 , G05F1/62
CPC分类号： H02M3/1582 , H02M2001/008 , H02M2001/009
摘要： A power converter for use in converting a variable DC input voltage into a variable DC output voltage is disclosed which uses control circuitry on both the input and the output to optimize converter performance. By charging the inductor up nearly to the saturation point, but completely avoiding saturation of the inductor, power capability at the input end is maximized. By discharging the inductor completely without either losing power capability by continuing to attempt to discharge the inductor after the charge is depleted or by failing to nearly discharge the inductor thereby presenting the possibility of saturation to the boosting of current through the inductor during the next charge cycle.

3. 发明授权

US4732043A System and method for obtaining digital outputs from multiple transducers 失效
标题翻译：用于从多个传感器获取数字输出的系统和方法
公开(公告)号：US4732043A
公开(公告)日：1988-03-22
申请号：US895904
申请日：1986-08-11
申请人： Robert L. Bell , Herman L. Renger
发明人： Robert L. Bell , Herman L. Renger
IPC分类号： G01R23/10 , H03M1/12 , H03M1/60 , G01L9/12 , G01L19/04
CPC分类号： G01R23/10 , H03M1/1225 , H03M1/60
摘要： A method and apparatus are disclosed for deriving digital signals from analog variations of different sensing elements in a transducer. Each sensing device controls the frequency of a variable frequency oscillator, which is energized when a reading is to be taken for that specific sensing device. The periodic signal is coupled to a first counter which counts a presettable total number of cycles so as to establish a variable time period proportioned to the value represented by the then existing state of the sensing device. Concurrently, a second counter is operated for a like time interval, but counts cycles from a fixed frequency clock source at a much higher frequency. The number of cycles counted by the second counter is proportional to the analog signal from the sensing device. This arrangement enables the analog signals from the sensing devices to be digitized in sequence with compact circuitry having low power drain. The different values derived from the sensing device can be used in complex analysis of one or more parameters that are being evaluated, without danger of interharmonics, cross talk or interference between the different units. By changing the presettings of the first counter, the resolution of the transducer can be varied, enabling operation in different ranges with adequate accuracy. Also, where a number of sensing elements are used in a transducer, resolution can be selectively varied when digitizing readings from the different elements.
摘要翻译：公开了一种用于从换能器中的不同感测元件的模拟变化导出数字信号的方法和装置。每个感测装置控制可变频率振荡器的频率，该频率振荡器在对该特定感测装置进行读取时被激励。周期信号耦合到第一计数器，该第一计数器对可预置的总周期数进行计数，以便建立与由感测装置的当时存在状态表示的值成比例的可变时间段。同时，第二计数器以相同的时间间隔运行，但以高得多的频率对来自固定频率时钟源的周期进行计数。由第二计数器计数的周期数与来自感测装置的模拟信号成比例。这种布置使得来自感测装置的模拟信号可以依次具有低功耗的紧凑型电路进行数字化。来自感测装置的不同值可以用于正在评估的一个或多个参数的复杂分析，而不会发生间谐波，串扰或不同单元之间的干扰的危险。通过改变第一个计数器的预置位，换能器的分辨率可以改变，使得能够在不同的范围内以足够的精度进行操作。此外，当在换能器中使用多个感测元件时，当从不同元件读取数字化时，可以选择性地改变分辨率。

4. 发明授权

US07390314B2 Lead screw driven reservoir with integral plunger nut and method of using the same 有权
标题翻译：具有整体柱塞螺母的丝杠驱动油箱及其使用方法
公开(公告)号：US07390314B2
公开(公告)日：2008-06-24
申请号：US10379627
申请日：2003-03-05
申请人： William H. Stutz, Jr. , Herman L. Renger , Cary D. Talbot
发明人： William H. Stutz, Jr. , Herman L. Renger , Cary D. Talbot
IPC分类号： A61M5/20 , A61M5/00
CPC分类号： A61M5/1456 , A61M2005/14573
摘要： An improved reservoir is provided for use in a medication infusion device for operating the reservoir to administer a fluid to a patient. The reservoir comprises a hollow barrel adapted to receive a supply of fluid for delivery through infusion tubing or the like to the patient, in combination with a reservoir plunger. The reservoir plunger is designed to engage a motor-driven lead screw of the medication infusion device. The reservoir plunger has an integral split nut connector formed on the end of the plunger, which is in co-axial alignment with the lead screw whereby the split nut connector can be engaged directly to the lead screw.
摘要翻译：提供改进的储存器用于药物输注装置，用于操作储存器以向患者施用流体。储存器包括适于接收流体供应的中空筒，用于通过输注管等输送到患者，与储存器柱塞组合。储存器柱塞被设计成与药物输注装置的马达驱动的丝杠接合。储液柱塞具有形成在柱塞的端部上的一体的分离螺母连接件，该螺母连接件与导螺杆同轴对准，由此分体式螺母连接器可以直接接合到导螺杆。

5. 发明授权

US5598847A Implantable flow sensor apparatus and method 失效
标题翻译：植入式流量传感器装置及方法
公开(公告)号：US5598847A
公开(公告)日：1997-02-04
申请号：US365265
申请日：1994-12-28
申请人： Herman L. Renger
发明人： Herman L. Renger
IPC分类号： A61B5/028 , G01F1/688 , A61B5/00
CPC分类号： A61B5/6876 , A61B5/028 , A61B5/6884 , G01F1/6886
摘要： An implantable blood flow sensor for measuring a blood flow rate through a blood vessel within a person's body. The flow sensor includes a rigid cylindrical tube, sized to fit within the blood vessel, a heater attached to the tube, and a pyroelectric detector located within the tube. A predetermined amount of heat energy is produced by the heater and the pyroelectric detector monitors the resultant temperature change and generates a temperature signal based on the temperature change. A processor generates a data signal, based on the temperature change, that indicates the blood flow rate through the blood vessel or artery. The rigid tube protects the pyroelectric detector from external forces that may produce unwanted signals due to piezoelectric effects. Additionally, the heater may be incorporated into one of the electrodes of the pyroelectric detector as a serpentine path in the electrode that forms a resistive heating element. Also, a switch may be provided that prevents induced voltage signals caused by currents through the heater from reaching the processor.
摘要翻译：一种用于测量通过人体内血管的血流量的可植入血流传感器。流量传感器包括一个刚性的圆柱形管，其尺寸适于装配在血管内，一个连接在管上的加热器和位于管内的热电探测器。通过加热器产生预定量的热能，并且热释电检测器监测所得到的温度变化并基于温度变化产生温度信号。处理器基于温度变化产生指示通过血管或动脉的血流量的数据信号。刚性管保护热电检测器免受由于压电效应而产生不想要的信号的外力。此外，加热器可以作为形成电阻加热元件的电极中的蛇形路径结合到热电检测器的一个电极中。此外，可以提供防止由通过加热器的电流引起的感应电压信号到达处理器的开关。

6. 发明授权

US5496352A Activity sensors for implantable medical devices 失效
标题翻译：用于可植入医疗器械的活动传感器
公开(公告)号：US5496352A
公开(公告)日：1996-03-05
申请号：US223079
申请日：1994-04-04
申请人： Herman L. Renger
发明人： Herman L. Renger
IPC分类号： A61N1/365 , G01P15/09 , G01P15/18 , H01L41/04
CPC分类号： G01P15/18 , A61N1/36542 , G01P15/0922 , G01P2015/084
摘要： An implantable medical device including a piezoelectric accelerometer activity sensor. The activity sensor includes a thin film piezoelectric cell within a frame structure. A mass imposes a load based upon acceleration to apply lateral or transverse forces which cause the generation of an electrical potential within the piezoelectric cell, which can be used by a rate control algorithm within the device to control operation of the device.
摘要翻译：一种可植入医疗装置，包括压电加速计活动传感器。活动传感器包括框架结构内的薄膜压电单元。质量基于加速度施加负载以施加导致在压电单元内产生电势的横向或横向力，该力可由装置内的速率控制算法用于控制装置的操作。

7. 发明授权

US5006110A Air-in-line detector infusion system 失效
标题翻译：空气在线检测器输液系统
公开(公告)号：US5006110A
公开(公告)日：1991-04-09
申请号：US128121
申请日：1987-12-01
申请人： Michi E. Garrison , John P. Pelmulder , Herman L. Renger
发明人： Michi E. Garrison , John P. Pelmulder , Herman L. Renger
IPC分类号： A61M5/00 , A61M1/00 , A61M5/142 , A61M5/36 , G01N21/85
CPC分类号： A61M5/365 , G01N21/85 , A61M2205/12 , Y10S128/12 , Y10S128/13
摘要： An air-in-line detection system for use in detecting air bubbles in the fluid line of a disposable cassette mounted on a main pump unit is disclosed which can accurately detect air bubbles in any type of fluid, whether clear or opaque. The system uses an optical module mounted on the main pump unit to supply light and to detect light returned from the cassette, and an optical viewing area in the fluid flow path near the outlet end of the cassette. An inverted prism in the optical viewing path reflects light back to the optical module when air is contained in the fluid flow path adjacent the optical viewing area, with the light not being returned if there are no air bubbles contained in the fluid flow path.

8. 发明授权

US5557967A Thermopile flow sensor 失效
标题翻译：热电堆流量传感器
公开(公告)号：US5557967A
公开(公告)日：1996-09-24
申请号：US393955
申请日：1995-02-24
申请人： Herman L. Renger
发明人： Herman L. Renger
IPC分类号： A61B5/028 , A61N1/365 , G01F1/684 , G01F1/688 , G01F1/698 , G01F1/68
CPC分类号： G01F1/6847 , A61B5/028 , A61N1/36514 , G01F1/6888 , G01F1/6986 , A61N1/36571
摘要： A flow sensor adapted for placement along a pacing lead or other catheter comprises a thermopile formed on the outer surface of a tubular substrate. The thermopile comprises a plurality of interconnected conductors of an alternating metal type. Junctions between conductors of the thermopile are alternately located near the longitudinal ends of the flow sensor, so that a voltage generated by the thermopile indicates the difference in temperature between the ends of the flow sensor. To measure blood flow with the flow sensor, an alternating current is induced through the thermopile to heat the flow sensor in a generally symmetrical manner. A voltage generated by the thermopile is then measured to obtain a sample of the magnitude and direction of the velocity of blood flow.
摘要翻译：适于沿着起搏引线或其他导管放置的流量传感器包括形成在管状基底的外表面上的热电堆。热电堆包括交替金属类型的多个互连的导体。热电堆的导体之间的接合部交替地位于流量传感器的纵向端部附近，使得由热电堆产生的电压表示流量传感器端部之间的温差。为了用流量传感器测量血液流量，通过热电堆引起交流电流，以大致对称的方式加热流量传感器。然后测量由热电堆产生的电压，以获得血流速度的大小和方向的样本。

9. 发明授权

US5488553A Power converter apparatus for defibrillating cardiac pacemaker 失效
标题翻译：用于除颤心脏起搏器的功率转换装置
公开(公告)号：US5488553A
公开(公告)日：1996-01-30
申请号：US168735
申请日：1993-12-15
申请人： Herman L. Renger
发明人： Herman L. Renger
IPC分类号： A61N1/39 , A61N1/00
CPC分类号： A61N1/3925 , A61N1/3975
摘要： A power converter apparatus adapted for use in a defibrillating cardiac pacemaker, to selectively provide a prescribed high voltage useful in treating a cardiac fibrillation. A pulse generator-cyclically applies a relatively low battery voltage V.sub.s to a step-up transformer, to controllably charge a high-voltage capacitor. The time durations of the cyclic applications of the battery voltage V.sub.s are controlled by digital feedback of several parameters, including peak transformer current, average transformer current., battery voltage V.sub.s, and the voltage on the high-voltage capacitor. If any of the measured parameters is determined to be outside a predetermined limit, the pulsing of the transformer is incrementally modified. A smooth, efficient charging of the high-voltage capacitor thereby is provided.
摘要翻译：一种适于在去纤颤心脏起搏器中使用的功率转换器装置，以选择性地提供可用于治疗心脏颤动的规定高电压。脉冲发生器周期性地向升压变压器施加相当低的电池电压Vs，以可控制地对高压电容器充电。电池电压Vs的循环应用的持续时间由几个参数的数字反馈控制，包括峰值变压器电流，平均变压器电流，电池电压Vs和高压电容器上的电压。如果任何测量参数被确定为超出预定极限，则变压器的脉冲被逐渐地修改。因此提供了高压电容器的平滑高效充电。

10. 发明授权

US5126589A Piezoelectric driver using resonant energy transfer 失效
标题翻译：使用谐振能量转移的压电驱动器
公开(公告)号：US5126589A
公开(公告)日：1992-06-30
申请号：US575922
申请日：1990-08-31
申请人： Herman L. Renger
发明人： Herman L. Renger
IPC分类号： A61M1/12 , B06B1/02 , G10K9/122 , H01L41/04 , H03K17/687
CPC分类号： H01L41/042 , B06B1/023 , B06B2201/55
摘要： A drive circuit for use with a capacitive load includes two transistors controlled by a drive voltage and connected to the load through an inductor. A supply voltage is alternately connected and disconnected to the circuit to achieve a resonant transfer of energy from the supply voltage. Energy stored in the load is transferred to the inductor and then back to the load, thereby reversing and augmenting the output voltage across the load and providing an instantaneous output voltage many times the supply voltage. Diodes ensure that the current flows in the proper polarity through the transistors.

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