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1. 发明授权

US4328202A Ionic 5-C-substituted 2,4,6-triiodoisophthalic acid derivatives 失效
标题翻译：离子5-C取代的2,4,6-三碘代邻苯二甲酸衍生物
公开(公告)号：US4328202A
公开(公告)日：1982-05-04
申请号：US223634
申请日：1981-01-09
申请人： Heinz Gries , Heinrich Pfeiffer , Ulrich Speck , Wolfgang Muetzel
发明人： Heinz Gries , Heinrich Pfeiffer , Ulrich Speck , Wolfgang Muetzel
IPC分类号： C07C69/80 , A61K31/16 , A61K31/165 , A61K31/19 , A61K31/235 , A61K31/24 , A61K49/04 , C07C20060101 , C07C55/00 , C07C61/00 , C07C63/08 , C07C63/10 , C07C63/30 , C07C63/307 , C07C63/68 , C07C67/00 , C07C69/76 , C07C231/00 , C07C233/47 , C07C233/65 , C07C233/69 , C07C233/92 , C07C235/42 , C07C237/30 , C07C237/46 , C07F13/00
CPC分类号： C07C233/92 , C07C233/65 , C07C233/69 , C07C237/42 , Y10S430/168
摘要： Ionic compounds of the formula ##STR1## wherein X is --CONR.sub.1 R.sub.2, --CH.sub.2 NH.multidot.Acyl or --CH.sub.2 OH; Y is --NR.sub.3 R.sub.4, --NH.multidot.Acyl or OR.sub.5 ; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 can be identical or different, and each is hydrogen, C.sub.1-6 - alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, R.sub.5 is C.sub.1-6 alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, and Acyl, which can be the same or different in X and Y, is C.sub.2-6 -alkanoyl or C.sub.2-6 -alkanoyl substituted by 1-4 OH groups and/or by one C.sub.1-3 -alkoxy group, or a physiologically compatible salt thereof with an inorganic or organic base, have valuable properties as X-ray contrast agents.
摘要翻译：式（I）的离子化合物，其中X是-CONR1R2，-CH2NHxAc或-CH2OH; Y是-NR 3 R 4，-NH x Acyl或OR 5; R 1，R 2，R 3和R 4可以相同或不同，各自为氢，被1-5个OH基团取代的C 1-6 - 烷基或C 2-8 - 烷基和/或被一个C 1-3 - 烷氧基取代，R 5是 C 1-6烷基或被1-5个OH基团和/或一个C 1-3 - 烷氧基取代的C 2-8 - 烷基，X和Y可以相同或不同的酰基是C 2-6 - 烷酰基或被1-4个OH基团和/或一个C 1-3 - 烷氧基取代的C 2-6 - 烷酰基或其与无机或有机碱的生理上相容的盐具有作为X射线造影剂的有价值的性质。

2. 发明授权

US5047228A Nonionic 5-C-substituted 2,4,6-triiodoisophthalic acid derivatives 失效
标题翻译：非离子型5-C取代的2,4,6-三碘代邻苯二甲酸衍生物
公开(公告)号：US5047228A
公开(公告)日：1991-09-10
申请号：US318454
申请日：1989-03-02
申请人： Heinz Gries , Heinrich Pfeiffer , Ulrich Speck , Wolfgang Mutzel
发明人： Heinz Gries , Heinrich Pfeiffer , Ulrich Speck , Wolfgang Mutzel
IPC分类号： C07C69/80 , A61K49/04 , C07C63/68 , C07C67/00 , C07C69/76 , C07C231/00 , C07C231/02 , C07C231/06 , C07C233/65 , C07C233/68 , C07C233/69 , C07C237/30 , C07C237/32
CPC分类号： C07C233/69
摘要： Nonionic compounds of the formula ##STR1## wherein X is --CONR.sub.1 R.sub.2, --COOR.sub.3, --CH.sub.2 NHR.sub.7 or --CH.sub.2 OH; Y is --1R.sub.1 R.sub.2 or --OR.sub.3 ; and Z is --NR.sub.1 R.sub.2, --NHR.sub.7 or --OR.sub.3 ; and wherein R.sub.1 R.sub.2 and R.sub.3 in X, Y or Z, and R.sub.7 in X and Z, are identical or different, R.sub.1 and R.sub.2, and each is hydrogen, C.sub.1-6 -alkyl or C.sub.2-8 - alkyl substituted by 1-5 OH groups and/or by a C.sub.1-3 -alkoxy group; R.sub.3 is C.sub.1-4 -alkyl or C.sub.2-4 -alkyl substituted by 1-2 OH groups and/or by a C.sub.1-3 -alkoxy group; and R.sub.7 is an acyl group of a C.sub.2-5 OH group and/or by a C.sub.1-3 -alkoxy group are highly advantageous X-ray contrast agents.
摘要翻译：其中X为-CONR1R2，-COOR3，-CH2NHR7或-CH2OH的式（I）的非离子化合物; Y为-1R1R2或-OR3; 并且Z是-NR 1 R 2，-NHR 7或-OR 3; 并且其中X，Y或Z中的R 1和R 3以及X和Z中的R 7相同或不同，R 1和R 2各自为氢，C 1-6 - 烷基或被1-5 OH取代的C 2-8 - 烷基基团和/或被C 1-3 - 烷氧基取代; R3是被1-2个OH基团和/或被C1-3烷氧基取代的C 1-4 - 烷基或C 2-4 - 烷基; R7是C2-5OH基和/或C1-3烷氧基的酰基是非常有利的X射线造影剂。

3. 发明授权

US4963344A Method to enhance NMR imaging using chelated paramagnetic ions 失效
标题翻译：使用螯合顺磁离子增强核磁共振成像的方法
公开(公告)号：US4963344A
公开(公告)日：1990-10-16
申请号：US370139
申请日：1989-06-23
申请人： Heinz Gries , Douwe Rosenberg , Hanns-Joachim Weinmann , Ulrich Speck , Wolfgang Mutzel , Georg-Alexander Hayden , Heinrich Pfeiffer
发明人： Heinz Gries , Douwe Rosenberg , Hanns-Joachim Weinmann , Ulrich Speck , Wolfgang Mutzel , Georg-Alexander Hayden , Heinrich Pfeiffer
IPC分类号： A61K49/04 , A61K49/06 , A61K49/10 , A61K49/18 , C07C323/25 , C07D257/02 , C07F9/38 , G01R33/28
CPC分类号： C07C323/25 , A61K49/04 , A61K49/085 , A61K49/10 , A61K49/103 , A61K49/105 , A61K49/106 , A61K49/108 , A61K49/143 , A61K49/16 , A61K49/18 , A61K49/1806 , A61K49/1809 , A61K49/1812 , C07D257/02 , C07F9/3817 , C07F9/386 , G01R33/5601 , Y10S436/806 , Y10S514/836 , Y10T436/24
摘要： Agents useful for influencing the relaxation times in NMR diagnostics, contain at least one paramagnetic, physiologically compatible complex salt comprising a chelate from an open-chain or cyclic complex-forming compound containing organic nitrogen, phosphorus, oxygen and/or sulfur, and a complexed ion of the lanthanide elements of atomic number 57-70 or of the transition metals of atomic numbers 21-29, 42 and 44, and, optionally, an inorganic or organic base or acid.
摘要翻译：可用于影响核磁共振诊断中松弛时间的试剂含有至少一种顺磁性，生理上相容的复盐，其包含来自含有机氮，磷，氧和/或硫的开链或环状络合物形成化合物的螯合物，以及络合物原子序数57-70的镧系元素或原子序数21-29,42和44的过渡金属的离子，以及任选的无机或有机碱或酸。

4. 发明授权

US5560903A Method of enhancing paramagnetism in chelates for MRI 失效
标题翻译：增强MRI中螯合物顺铂的方法
公开(公告)号：US5560903A
公开(公告)日：1996-10-01
申请号：US462681
申请日：1995-06-05
申请人： Heinz Gries , Douwe Rosenberg , Hanns-Joachim Weinmann , Ulrich Speck , Wolfgang Mutzel , Georg-Alexander Hoyer , Heinrich Pfeiffer , Franz-Josef Renneke
发明人： Heinz Gries , Douwe Rosenberg , Hanns-Joachim Weinmann , Ulrich Speck , Wolfgang Mutzel , Georg-Alexander Hoyer , Heinrich Pfeiffer , Franz-Josef Renneke
IPC分类号： A61K49/04 , A61K49/06 , A61K49/10 , A61K49/18 , C07C323/25 , C07D257/02 , C07F9/38 , G01R33/28 , A61B5/055
CPC分类号： G01R33/5601 , A61K49/04 , A61K49/085 , A61K49/10 , A61K49/103 , A61K49/105 , A61K49/106 , A61K49/108 , A61K49/143 , A61K49/16 , A61K49/1806 , A61K49/1809 , A61K49/1812 , C07C323/25 , C07D257/02 , C07F9/3817 , C07F9/386 , Y10S514/836 , Y10T436/24
摘要： A diagnostic medium contains at least one physiologically well tolerated complex salt comprising an anion of a complexing acid and one or more central ion or ions of an element with an atomic number of 21 to 29, 42, 44 or 57 to 83 and, optionally, one or more physiologically biocompatible cation or cations of an inorganic and/or organic base or amino acid, optionally, with additives customary in galenic formulations, dissolved or suspended in an aqueous medium.
摘要翻译：诊断介质包含至少一种生理上良好耐受的复合盐，其包含络合酸的阴离子和一种或多种原子序数为21至29,42,44或57至83的元素的中心离子或离子，以及任选地，一种或多种无机和/或有机碱或氨基酸的生理学上生物相容的阳离子或阳离子，任选地与通常用于盖伦制剂中的添加剂一起溶解或悬浮在水性介质中。

5. 发明授权

US4001298A Triiodized N-methyldicarboxylic acid anilides 失效
标题翻译：三聚N-甲基胆酰胺酸抗体
公开(公告)号：US4001298A
公开(公告)日：1977-01-04
申请号：US281379
申请日：1972-08-17
申请人： Heinz Gries , Heinrich Pfeiffer
发明人： Heinz Gries , Heinrich Pfeiffer
IPC分类号： C07C231/00 , A61K49/04 , C07C67/00 , C07C229/42 , C07C231/02 , C07C231/12 , C07C233/54 , C07C235/16 , C07D207/26 , C07D207/27 , C07C101/50
CPC分类号： C07D207/27 , A61K49/0433
摘要： Triiodized N-methyldicarboxylic acid anilides of the Formula ##STR1## wherein R.sub.1 is hydrogen, halogen, carboxyl, N-monoacylamino, N-monoalkoxyacylamino, N-alkyl-N-acylamino, N-alkyl-N-alkoxyacylamino, N,N-diacylamino, N-acylaminomethyl, ##STR2## wherein A is alkylene of 2 or 3 carbon atoms which can be interrupted by an oxygen atom, and R.sub.3 and R.sub.4 are each hydrogen, lower alkyl or hydroxyalkyl, or R.sub.3 and R.sub.4 together with the nitrogen atom form a 5 to 7 member heterocyclic ring which can contain a further oxygen, nitrogen, or sulfur hetero atom; R.sub.2 is halogen, hydroxy, lower alkoxy, hydroxyalkoxy or alkoxyalkoxy; and X is straight or branched alkylene of 2-14 carbon atoms interrupted by one or more oxygen or sulfur atoms, and the salts of these compounds with physiologically compatible bases are valuable radiopaque agents.

6. 发明授权

US6049962A Process for connecting a pipe with a press fitting and combination of press fitting, pipe and pressing device for implementing said process 失效
标题翻译：用于连接管道与压配合件以及压配件，管道和压装置的组合的方法，用于实现所述过程
公开(公告)号：US6049962A
公开(公告)日：2000-04-18
申请号：US68160
申请日：1998-05-04
申请人： Heinrich Pfeiffer
发明人： Heinrich Pfeiffer
IPC分类号： F16L13/16 , B21D39/00 , B23P11/00
CPC分类号： F16L13/142 , Y10T29/49925 , Y10T29/49927 , Y10T29/53996
摘要： In a process, a pipe (1) is connected to a press fitting (2) which has a cylindrical section (3) and a radially outward-projecting annular bead (5) at each end which, at the free end of the press fitting (2) has an inwardly directed bead shoulder (8) and internally forms an annular groove (10) in which is fitted a sealing ring (11). In order to make the connection, the press fitting (2) and the pipe (1) are inserted one into the other and the annular bead (5) and the cylindrical section (3) are pressed radially inwards with the plastic deformation of the pipe (1) as well. This is done by pressing the bead shoulder (8) into the pipe (1) to form a first narrowing (44), and a second narrowing (43) is formed in the pipe by pressing the cylindrical section (3) at a distance from the first narrowing (44) such that the shaping of the second narrowing (43) is separated from the first (44) In such a way that the first narrowing (44) has a radially outwardly projecting section (47) towards the second.
摘要翻译： PCT No.PCT / EP96 / 04719 371日期：1998年5月4日 102（e）日期1998年5月4日PCT 1996年10月30日PCT公布。出版物WO97 / 17563 日期1997年5月15日在一个过程中，管（1）连接到压配合件（2），每个端部具有圆柱形部分（3）和径向向外突出的环形凸缘（5），在自由端压配合件（2）具有向内定向的胎圈（8），并且内部形成环形槽（10），其中安装有密封环（11）。为了进行连接，将压配合件（2）和管道（1）一个插入另一个中，并且环形凸缘（5）和圆柱形部分（3）被径向向内挤压，管道的塑性变形（1）。这是通过将胎圈肩部（8）压入管（1）中以形成第一变窄（44），并且通过将圆柱形部分（3）在一定距离处按压而在管中形成第二变窄部（43）第一变窄（44）使得第二变窄（43）的成形与第一（44）In分离，使得第一变窄（44）朝向第二变窄（44）具有径向向外突出的部分（47）。

7. 发明授权

US4348252A Device for the insertion and extraction of a laminating pack in and from a press 失效
标题翻译：用于在压机中插入和提取层压包装置的装置
公开(公告)号：US4348252A
公开(公告)日：1982-09-07
申请号：US253017
申请日：1981-04-10
申请人： Heinrich Knoop , Heinrich Pfeiffer
发明人： Heinrich Knoop , Heinrich Pfeiffer
IPC分类号： B27N3/20 , B30B15/30 , B30B15/32
CPC分类号： B30B15/30 , B27N3/20 , B30B15/32 , Y10T156/17
摘要： A single unit moves into and out of a press to essentially simultaneously charge the press with the workpiece to be processed and discharge another workpiece which has been processed. The device is particularly suitable for preparing laminates in which the workpiece to be processed comprises a stack of alternating sheets of solid material and bonding material. This workpiece is referred to as a laminating pack. A table on a transfer car holds the unprocessed laminating pack. This same transfer car also has on its lower side a plurality of suction devices for grippingly engaging a processed laminate, i.e., a laminate that has been treated in the heat press. The transfer car holding the unprocessed laminating pack advances into an open press. In the press, the laminating pack is transported onto holding gibs, and the processed laminate in the press is taken up by the suction means on the bottom side of the transfer car. The transfer car is then retracted from the press with the processed laminate, and the laminating pack is left behind in the press for processing. This simultaneous charging and discharging operation is then repeated.
摘要翻译：单个单元移入和移出压力机，以基本上同时对要加工的工件对压机进行充电，并排出已经处理的另一个工件。该装置特别适用于制备层压板，其中待加工的工件包括一堆交替的固体材料和粘合材料片。该工件被称为层压包装。转运车上的一张桌子保持未加工的层压包装。该相同的转运车还在其下侧上具有多个用于夹紧地接合经处理的层压体，即已经在热压机中处理过的层压板的抽吸装置。保持未加工的层压包的转运车进入开式压机。在压机中，层压包装被运送到保持件上，并且压榨机中的加工层压体被转运车底部的抽吸装置吸收。然后将转运车从压榨机中与处理的层压体一起退回，并且将层压包装留在压机中用于加工。然后重复同时的充放电操作。

8. 发明授权

US4221740A Process for the preparation of serinol (1,3-dihydroxy-2-aminopropane) 失效
标题翻译：丝氨醇（1,3-二羟基-2-氨基丙烷）的制备方法
公开(公告)号：US4221740A
公开(公告)日：1980-09-09
申请号：US943094
申请日：1978-09-18
申请人： Heinrich Pfeiffer
发明人： Heinrich Pfeiffer
IPC分类号： C07C213/02 , C07C20060101 , C07C67/00 , C07C213/00 , C07C215/10 , C07C85/11
CPC分类号： C07C213/02
摘要： The sodium salt of 1,3-dihydroxy-2-nitropropane is catalytically hydrogenated in an inert solvent to produce 1,3-dihydroxy-2-aminopropane, which can be isolated in crystalline form.
摘要翻译： 1,3-二羟基-2-硝基丙烷的钠盐在惰性溶剂中催化氢化，得到1,3-二羟基-2-氨基丙烷，其可以以结晶形式分离。

9. 发明授权

US08782863B2 Press tool for connecting in particular tubular workpieces 有权
标题翻译：用于连接特定管状工件的压力工具
公开(公告)号：US08782863B2
公开(公告)日：2014-07-22
申请号：US13383349
申请日：2010-07-02
申请人： Heinrich Pfeiffer
发明人： Heinrich Pfeiffer
IPC分类号： B25B27/10
CPC分类号： B21D39/048 , B25B27/10
摘要： A press tool, such as a press sling for pressing in particular tubular workpieces, comprises a plurality of articulated press elements connected to one another in the form of a chain. The press tool is open between two end press elements for forming a closing site between two end press elements. In order to unlatch the press tool from a closed position in which the closing site is substantially closed, a handling element is provided according to the disclosure. Said tool alternatively also serves for releasing a press jaw mounted on a press jaw carrier.
摘要翻译：诸如用于压制特定管状工件的压力吊带的压制工具包括以链的形式彼此连接的多个铰接式压力元件。压力机工具在两个最终按压元件之间打开，用于形成两个最终按压元件之间的关闭位置。为了将压制工具从关闭位置基本上封闭的关闭位置解锁，根据本公开提供了处理元件。所述工具还可用于释放安装在压力钳座上的压力钳。

10. 发明授权

US5666711A Press tool 失效
标题翻译：按工具
公开(公告)号：US5666711A
公开(公告)日：1997-09-16
申请号：US448436
申请日：1995-06-02
申请人： Heinrich Pfeiffer
发明人： Heinrich Pfeiffer
IPC分类号： B21D39/04 , B25B27/02 , B25B27/14
CPC分类号： B25B27/10 , B21D39/04 , Y10T29/53917 , Y10T29/53987 , Y10T29/53996
摘要： A press tool for joining workpieces has a wraparound ring consisting of hinged clamping components, in which the press tool is open at at least one closing point between the clamping components and has grips at that position for a closing device by means of which the clamping components can be brought together to form a closed ring. In order to facilitate handling the press tool especially with large pipe diameters, there is at least one coupling member (49, 50) by means of which the adjacent clamping components (6, 10) can be temporarily connected, the coupling member (49, 50) being designed so as to be flexible in the coupled position in the closing direction.
摘要翻译： PCT No.PCT / EP93 / 03050 Sec。 371日期：1995年6月2日 102（e）1995年6月2日PCT 1993年11月2日PCT公布。公开号WO94 / 12296 日期1994年6月9日用于连接工件的压制工具具有由铰接的夹紧部件组成的环绕环，其中冲压工具在夹紧部件之间的至少一个闭合点处打开，并且通过装置在该位置处具有用于闭合装置的夹具其中夹紧部件可以组合在一起以形成闭环。为了便于操作特别是具有较大管直径的冲压工具，至少有一个连接件（49,50）可以临时连接相邻的夹紧件（6,10），连接件（49， 50）被设计成在闭合方向上的联接位置是柔性的。

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