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1. 发明授权

US08258176B2 Dithiolopyrrolone compounds, the preparation and the use thereof 有权
标题翻译：二硫代罗环酮化合物，其制备及其应用
公开(公告)号：US08258176B2
公开(公告)日：2012-09-04
申请号：US12676470
申请日：2008-08-29
申请人： Guoping Wang , Quanhai Liu , Haiyan Sun , Wei Wu , Jian Hou , Lin Yao , Chungang Li , Minyu Liu , Fei Li , Xuejun Wu , Shuai Zhao
发明人： Guoping Wang , Quanhai Liu , Haiyan Sun , Wei Wu , Jian Hou , Lin Yao , Chungang Li , Minyu Liu , Fei Li , Xuejun Wu , Shuai Zhao
IPC分类号： A61K31/407 , C07D487/04 , C07D487/02
CPC分类号： C07D495/04
摘要： The invention discloses a dithiolopyrrolone compound represented by formula I or its pharmaceutically acceptable salts, wherein X1, R1, R2, R3, R4 are defined as in the description. The invention also discloses the preparation of such compounds, and the use of such compounds in preparation of medicaments for increasing peripheral white blood cells and in preparation of ancillary medicaments for inhibiting the decrease of peripheral white blood cells in radiotherapy or chemotherapy.
摘要翻译：本发明公开了由式I表示的二硫代环吡咯酮化合物或其药学上可接受的盐，其中X1，R1，R2，R3，R4如描述中所定义。本发明还公开了这样的化合物的制备，以及这些化合物在制备用于增加外周白细胞的药物中的用途以及用于抑制放射治疗或化学疗法中外周白细胞减少的辅助药物。

2. 发明申请

US20100210856A1 DITHIOLOPYRROLONE COMPOUNDS, THE PREPARATION AND THE USE THEREOF 有权
标题翻译：二羟基吡咯烷酮化合物，其制备及其用途
公开(公告)号：US20100210856A1
公开(公告)日：2010-08-19
申请号：US12676470
申请日：2008-08-29
申请人： Guoping Wang , Quanhai Liu , Haiyan Sun , Wei Wu , Jian Hou , Lin Yao , Chungang Li , Minyu Liu , Fei Li , Xuejun Wu , Shuai Zhao
发明人： Guoping Wang , Quanhai Liu , Haiyan Sun , Wei Wu , Jian Hou , Lin Yao , Chungang Li , Minyu Liu , Fei Li , Xuejun Wu , Shuai Zhao
IPC分类号： C07D495/04
CPC分类号： C07D495/04
摘要： The invention discloses a dithiolopyrrolone compound represented by formula I or its pharmaceutically acceptable salts, wherein X1, R1, R2, R3, R4 are defined as in the description. The invention also discloses the preparation of such compounds, and the use of such compounds in preparation of medicaments for increasing peripheral white blood cells and in preparation of ancillary medicaments for inhibiting the decrease of peripheral white blood cells in radiotherapy or chemotherapy.
摘要翻译：本发明公开了由式I表示的二硫代环吡咯酮化合物或其药学上可接受的盐，其中X1，R1，R2，R3，R4如描述中所定义。本发明还公开了这样的化合物的制备，以及这些化合物在制备用于增加外周白细胞的药物中的用途以及用于抑制放射治疗或化学疗法中外周白细胞减少的辅助药物。

3. 发明授权

US08742167B2 Therapeutic formulations based on asiatic acid and selected salts thereof 有权
标题翻译：基于积雪草酸及其选择的盐的治疗剂型
公开(公告)号：US08742167B2
公开(公告)日：2014-06-03
申请号：US12811477
申请日：2009-01-08
申请人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
发明人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
IPC分类号： C07C61/29
CPC分类号： C07J63/008
摘要： A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
摘要翻译：可以制备高纯度积雪草苷和药物级积雪草酸以及积雪草酸盐，用于配制适合于治疗关节炎，牛皮癣和其它炎性疾病以及肺纤维化，糖尿病性肾病和其他纤维化疾病。

4. 发明申请

US20100331413A1 Therapeutic Formulations Based on Asiatic Acid and Selected Salts Thereof 有权
标题翻译：基于亚洲酸及其选择盐的治疗配方
公开(公告)号：US20100331413A1
公开(公告)日：2010-12-30
申请号：US12811477
申请日：2009-01-08
申请人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
发明人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
IPC分类号： A61K31/19 , C07C62/32 , C07C233/00 , C07C69/74 , C07H13/02 , A61P11/00 , A61P3/10 , A61P1/00 , A61P17/06 , A61P19/02
CPC分类号： C07J63/008
摘要： A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
摘要翻译：可以制备高纯度积雪草苷和药物级积雪草酸以及积雪草酸盐，用于配制适合于治疗关节炎，牛皮癣和其它炎性疾病以及肺纤维化，糖尿病性肾病和其他纤维化疾病。

5. 发明授权

US09651444B2 Method of cumulative helium mass spectrometric combination test by using argon as gross-leak tracer gas 有权
公开(公告)号：US09651444B2
公开(公告)日：2017-05-16
申请号：US14134006
申请日：2013-12-19
申请人： Genglin Wang , Ningbo Li , Fei Li
发明人： Genglin Wang , Ningbo Li , Fei Li
IPC分类号： G01N31/00 , G01M3/00 , G01M3/20
CPC分类号： G01M3/00 , G01M3/202
摘要： The present invention discloses a method of cumulative helium mass spectrometric combination test by using argon gas as gross-leak tracer gas, and specifically gives the procedure for this gross-leak and fine-leak combination test, comprising steps and methods of selecting helium-argon prefilling method or helium-argon pressuring method, fixed or flexible scheme and the criterion RAr0max for argon measured leak rate of gross-leak test according to the rigour grade THemin, cavity volume, leak rate of surficially absorbed helium and argon and the history of the test of a component under test; designing time for pressuring of helium-argon pressuring method, the maximum test-waiting time of fine-leak test and the criterion for helium measured leak rate, helium-argon prefilling and helium-argon pressuring, removing absorbed helium and argon gas, gross-leak test, fine-leak test and complementally testing bigger gross leak, which enhances the sensitivity of gross-leak test, lengthens the maximum test-waiting time of fine-leak test, tremendously expands the range of adapted cavity volume and criterion for measured leak rate of fine-leak test, thus making the cumulative helium mass spectrometric combination test more applicable, convenient and practical.

6. 发明授权

US09030106B2 Driving circuit and LED backlight module using multiple references voltages 有权
标题翻译：驱动电路和LED背光模块采用多个参考电压
公开(公告)号：US09030106B2
公开(公告)日：2015-05-12
申请号：US13379887
申请日：2011-12-02
申请人： Fei Li
发明人： Fei Li
IPC分类号： H05B37/00 , H05B33/08
CPC分类号： H05B33/0851
摘要： A driving circuit for a LED backlight module includes a brightness adjusting module, a current detector, a reference voltage adjusting module, and a comparing module. The current detector is capable of detecting the current of the brightness adjusting module and outputting a detecting result. The reference voltage adjusting module is capable of choosing the corresponding reference voltage corresponding to the detecting result of the current detector. Thus, the reference voltage outputted to the comparing module can be adjusted according to the change of the current of the brightness adjusting module. This reduces the power consumption and the amount of heat generated due to the power consumption, and improves the performance of the LED backlight module.
摘要翻译： LED背光模块的驱动电路包括亮度调节模块，电流检测器，参考电压调节模块和比较模块。电流检测器能够检测亮度调节模块的电流并输出检测结果。参考电压调节模块能够根据电流检测器的检测结果选择相应的参考电压。因此，可以根据亮度调整模块的电流的变化来调整输出到比较模块的参考电压。这降低了由于功耗而产生的功率消耗和热量，并且提高了LED背光模块的性能。

7. 发明授权

US09017332B2 Surgical milling cutter 有权
标题翻译：手术铣刀
公开(公告)号：US09017332B2
公开(公告)日：2015-04-28
申请号：US13823065
申请日：2011-09-15
申请人： Lei Ye , Jian Zhou , Hua Feng , Fei Li , Hengyang Zhu , Congxiao Li
发明人： Lei Ye , Jian Zhou , Hua Feng , Fei Li , Hengyang Zhu , Congxiao Li
IPC分类号： A61B17/00 , A61B17/16 , A61B17/32
CPC分类号： A61B17/16 , A61B17/162 , A61B17/1622 , A61B17/1624 , A61B17/32002 , A61B2017/1602
摘要： A surgical milling cutter includes a milling cutter holder, a locking device, a locking seat, and a main machine. The milling cutter holder includes a fixing seat with a through hole. A finger guider with an L-type holder on a top end thereof is arranged at an upper part of the fixing seat. A distal end of a short side of the L-type holder is disposed with a downward projection, and a lowest point of the projection is lower than that of a cylindrical head when the milling cutter works normally. A bolt with a central through hole is fixed in a cavity of the finger guider. A pressing disk is arranged at the upper part of the fixing seat, and a nut is connected to the bolt through a hole in the pressing disk.
摘要翻译：外科铣刀包括铣刀保持器，锁定装置，锁定座和主机。铣刀架包括具有通孔的固定座。在固定座的上部设置有在其顶端具有L型保持器的手指导杆。 L型保持器的短边的远端设置有向下的突起，并且当铣刀正常工作时，突起的最低点低于圆柱形头的最低点。具有中心通孔的螺栓固定在手指导板的空腔中。按压盘设置在固定座的上部，螺母通过按压盘上的孔连接到螺栓上。

8. 发明申请

US20150054859A1 DRIVING CIRCUIT AND DRIVING METHOD FOR LIGHT EMITTING DIODE AND DISPLAY APPARATUS USING THE SAME 有权
标题翻译：用于发光二极管的驱动电路和驱动方法及其使用的显示装置
公开(公告)号：US20150054859A1
公开(公告)日：2015-02-26
申请号：US13380883
申请日：2011-12-16
申请人： Xiang Yang , Fei Li
发明人： Xiang Yang , Fei Li
IPC分类号： G09G3/34 , G09G3/36
CPC分类号： G09G3/3406 , G09G3/3648 , G09G2320/062 , G09G2320/0626 , H05B33/0818 , Y02B20/346
摘要： The present invention provides a driving circuit and a driving method for light-emitting diodes (LEDs), and a display apparatus using the same. The driving circuit comprises a power switch and a dimmer circuit. The method comprising: providing a pulse width modulation (PWM) dimming signal and a high frequency dimming signal; and multiplying the PWM dimming signal and the high frequency dimming signal for providing a driving signal to the power switch. The present invention can improve a dimming effect of the LEDs.
摘要翻译：本发明提供了一种用于发光二极管（LED）的驱动电路和驱动方法，以及使用该驱动电路和驱动方法的显示装置。驱动电路包括电源开关和调光电路。该方法包括：提供脉宽调制（PWM）调光信号和高频调光信号; 并且将PWM调光信号和高频调光信号相乘，以向驱动开关提供驱动信号。本发明可以改善LED的调光效果。

9. 发明申请

US20150042233A1 LED Backlight Driving Circuit and LCD 有权
标题翻译： LED背光驱动电路和LCD
公开(公告)号：US20150042233A1
公开(公告)日：2015-02-12
申请号：US14112545
申请日：2013-08-14
申请人： Hua Zhang , Fei Li
发明人： Hua Zhang , Fei Li
IPC分类号： G09G3/34
CPC分类号： G09G3/3426 , G09G2330/02 , G09G2330/06 , H05B33/0815
摘要： The present invention proposes an LED backlight driving circuit comprises voltage booster circuits parallelly connected and a constant current driving IC module. The voltage booster circuits are used for conversing an input voltage into a needed output voltage to supply to an LED unit. The constant current driving IC module is used for controlling the voltage booster circuits, so that the voltage booster circuits converse the input voltage into the needed output voltage to supply to the LED unit, driving the LED unit in a constant current. The constant current driving IC module generates driving signals at different frequencies to control the voltage booster circuits respectively. The invention can set up multiple driving signals operating simultaneously at different frequencies respectively and disperse resulting harmonic wave, hence reduce EMI signals of the backlight driving circuit effectively. The present invention also proposes an LCD using the LED backlight driving circuit.
摘要翻译：本发明提出一种LED背光驱动电路，包括并联电压升压电路和恒流驱动IC模块。升压电路用于将输入电压转换成所需的输出电压以供应给LED单元。恒流驱动IC模块用于控制升压电路，使得升压电路将输入电压转换成所需的输出电压，以供给LED单元，以恒定电流驱动LED单元。恒流驱动IC模块分别产生不同频率的驱动信号，分别控制升压电路。本发明可以设置分别在不同频率同时工作的多个驱动信号并分散所产生的谐波，从而有效降低背光驱动电路的EMI信号。本发明还提出了一种使用LED背光驱动电路的LCD。

10. 发明授权

US08736238B2 Buck and buck/boost converter systems having auxiliary circuits and method thereof 有权
标题翻译：具有辅助电路的降压和降压/升压转换器系统及其方法
公开(公告)号：US08736238B2
公开(公告)日：2014-05-27
申请号：US12925336
申请日：2010-10-19
申请人： Fei Li , Hongjian Gan , Fei Ji , Xin Li
发明人： Fei Li , Hongjian Gan , Fei Ji , Xin Li
IPC分类号： H02M3/02
CPC分类号： H02M1/32 , H02M2001/0032 , Y02B70/16 , Y10T307/391
摘要： The configurations of a buck type and a buck/boost type converter systems and a controlling method thereof are provided in the present invention. The proposed buck/boost type converter system includes a rectifier bridge, a first auxiliary circuit including a first unidirectional switch coupled to the rectifier bridge and a second unidirectional switch coupled to the first unidirectional switch, a first capacitor coupled to the first unidirectional switch and the rectifier bridge, a buck/boost converter having a first input terminal coupled to the first unidirectional switch, a second input terminal coupled to the first capacitor, a first output terminal coupled to the second unidirectional switch and a second output terminal, a second capacitor electrically connected to the first and the second output terminals in parallel, and a DC source coupled to the second unidirectional switch.
摘要翻译：在本发明中提供了降压型和降压型/升压型转换器系统的结构及其控制方法。所提出的降压/升压型转换器系统包括整流桥，第一辅助电路，包括耦合到整流桥的第一单向开关和耦合到第一单向开关的第二单向开关，耦合到第一单向开关的第一电容器和整流桥，具有耦合到第一单向开关的第一输入端的降压/升压转换器，耦合到第一电容器的第二输入端子，耦合到第二单向开关的第一输出端子和第二输出端子，第二电容器电并联连接到第一和第二输出端子以及耦合到第二单向开关的DC源。

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