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1. 发明申请

US20140243553A1 AMORPHOUS ASIATIC TROMETHAMINE SALT AND PREPARATION METHOD THEREOF 有权
标题翻译：非晶亚硫胺盐及其制备方法
公开(公告)号：US20140243553A1
公开(公告)日：2014-08-28
申请号：US14006198
申请日：2012-03-21
申请人： Guobin Ren , Ying Liu , Jinyao Chen , Xiaoling Huang , Lin Xiao , Li Cai , Zhen Zhang , Xuejun Wu , Haiyan Sun , Quanhai Liu , Liling Jin , Minyu Liu , Yifang Deng , Zhiru Xu , Renhai Chen , Chungang Li , Xiangduan Tan , Yan Qin
发明人： Guobin Ren , Ying Liu , Jinyao Chen , Xiaoling Huang , Lin Xiao , Li Cai , Zhen Zhang , Xuejun Wu , Haiyan Sun , Quanhai Liu , Liling Jin , Minyu Liu , Yifang Deng , Zhiru Xu , Renhai Chen , Chungang Li , Xiangduan Tan , Yan Qin
IPC分类号： C07C227/14 , C07C229/38
CPC分类号： C07C227/14 , C07C215/10 , C07C229/38 , C07J63/008
摘要： An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
摘要翻译：一种无定形亚洲氨丁三醇盐及其制备方法。该方法包括以下步骤：（1）将积雪草酸溶解在有机溶剂中; 步骤（2）与氨丁三醇混合; 步骤（3）搅拌并使其成盐，然后除去有机溶剂。无定形亚洲氨基丁三醇盐的制备方法容易有效，与现有技术相比，所得到的亚稳氨基甲基胺盐的水溶性和生物利用度大大降低。

2. 发明授权

US08742167B2 Therapeutic formulations based on asiatic acid and selected salts thereof 有权
标题翻译：基于积雪草酸及其选择的盐的治疗剂型
公开(公告)号：US08742167B2
公开(公告)日：2014-06-03
申请号：US12811477
申请日：2009-01-08
申请人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
发明人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
IPC分类号： C07C61/29
CPC分类号： C07J63/008
摘要： A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
摘要翻译：可以制备高纯度积雪草苷和药物级积雪草酸以及积雪草酸盐，用于配制适合于治疗关节炎，牛皮癣和其它炎性疾病以及肺纤维化，糖尿病性肾病和其他纤维化疾病。

3. 发明申请

US20090255900A1 Oil/gas separation membrane, its use in gas sensor and process for producing the same 有权
标题翻译：油/气分离膜，其用于气体传感器及其生产过程
公开(公告)号：US20090255900A1
公开(公告)日：2009-10-15
申请号：US12455154
申请日：2009-05-28
申请人： Ren Yan Qin
发明人： Ren Yan Qin
IPC分类号： B32B38/10 , B32B37/12
CPC分类号： G01N33/2841 , B01D19/0031 , C10G31/11 , G01N2001/4016 , Y10T156/10
摘要： An oil gas separation membrane combines a gas permeable yet oil and temperature resistant bulk polymer membrane such as poly(tetrafluoroethylene) and poly(tetrafluoroethylene-co-hexafluoropropylene); a porous metal support such as sintered metal frit disk made with stainless steel, bronze or nickel; and an highly gas permeable adhesive that bonds firmly the bulk polymer membrane and the metal frit surface together. The adhesive is either a homogenous polymer that has desirable gas permeability, or a coalescent porous polymer particulates network. A gas sensor employing the oil gas separation membrane for detecting and monitoring fault gases of oil filled electrical equipment requires no mechanical wearing or moving part such as pump and valve and the gas sensor is operated normally under various temperature and pressure conditions
摘要翻译：油气分离膜结合了透气但耐油和耐温的本体聚合物膜，例如聚（四氟乙烯）和聚（四氟乙烯 - 共 - 六氟丙烯）; 多孔金属支撑体，例如用不锈钢，青铜或镍制成的烧结金属玻璃料盘; 以及高度透气的粘合剂，其将本体聚合物膜和金属玻璃料表面牢固地粘合在一起。粘合剂是具有期望的气体渗透性的均匀聚合物，或聚结多孔聚合物颗粒网络。采用油气分离膜检测和监测充油电气设备故障气体的气体传感器不需要机械磨损或运动部件如泵和阀，气体传感器在各种温度和压力条件下正常运行

4. 发明申请

US20210046025A1 Injection for Protecting Ischemic Myocardium and Preparation Method thereof 有权
公开(公告)号：US20210046025A1
公开(公告)日：2021-02-18
申请号：US16964995
申请日：2019-01-22
申请人： Yida TANG , Na CHU , Yan QIN
发明人： Yida TANG , Na CHU , Yan QIN
IPC分类号： A61K31/167 , A61K47/12 , A61K47/10 , A61K47/24 , A61K47/44 , A61K9/00 , A61P9/10
摘要： The present invention relates to an injection for protecting ischemic myocardium, and preparation method for the injection. The emulsion for injection comprises, in parts by weight: 1-5 parts of N-suberoylanilide hydroxamic acid, 0.2-12.5 parts of n emulsifying agent, 2-100 parts of oil for injection, 0.02-5 parts of a solubilizer, 0.03-0.4 part of oleic acid, 0.4-12.5 parts of glycerinum, and the balance being water for injection. The emulsion for injection can effectively be used for increasing local drug concentration of the N-suberoylanilide hydroxamic acid in lipophilic organs such as angiocarpy and/or tissues before a cardiac interventional operation, increasing the bioavailability of the N-suberoylanilide hydroxamic acid, reducing general side effects of the N-suberoylanilide hydroxamic acid, realizing effective protection on myocardium under an ischemic or reperfusion injury state, and reducing or avoiding the occurrence of myocardial infarction. Moreover, the emulsion for injection also provides a novel optional dosage form for application of the N-suberoylanilide hydroxamic acid in treatment of cancers.

5. 发明授权

US08962880B2 Amorphous asiatic tromethamine salt and preparation method thereof 有权
标题翻译：无定形亚洲氨丁三醇盐及其制备方法
公开(公告)号：US08962880B2
公开(公告)日：2015-02-24
申请号：US14006198
申请日：2012-03-21
申请人： Guobin Ren , Ying Liu , Jinyao Chen , Xiaoling Huang , Lin Xiao , Li Cai , Zhen Zhang , Xuejun Wu , Haiyan Sun , Quanhai Liu , Liling Jin , Minyu Liu , Yifang Deng , Zhiru Xu , Renhai Chen , Chungang Li , Xiangduan Tan , Yan Qin
发明人： Guobin Ren , Ying Liu , Jinyao Chen , Xiaoling Huang , Lin Xiao , Li Cai , Zhen Zhang , Xuejun Wu , Haiyan Sun , Quanhai Liu , Liling Jin , Minyu Liu , Yifang Deng , Zhiru Xu , Renhai Chen , Chungang Li , Xiangduan Tan , Yan Qin
IPC分类号： C07C227/14 , C07C215/10 , C07C229/38 , C07J63/00
CPC分类号： C07C227/14 , C07C215/10 , C07C229/38 , C07J63/008
摘要： An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
摘要翻译：一种无定形亚洲氨丁三醇盐及其制备方法。该方法包括以下步骤：（1）将积雪草酸溶解在有机溶剂中; 步骤（2）与氨丁三醇混合; 步骤（3）搅拌并使其成盐，然后除去有机溶剂。无定形亚洲氨基丁三醇盐的制备方法容易有效，与现有技术相比，所得到的亚稳氨基甲基胺盐的水溶性和生物利用度大大降低。

6. 发明授权

US08419961B2 Oil/gas separation membrane, its use in gas sensor and process for producing the same 有权
标题翻译：油/气分离膜，其用于气体传感器及其生产过程
公开(公告)号：US08419961B2
公开(公告)日：2013-04-16
申请号：US12455154
申请日：2009-05-28
申请人： Ren Yan Qin
发明人： Ren Yan Qin
IPC分类号： B32B37/00
CPC分类号： G01N33/2841 , B01D19/0031 , C10G31/11 , G01N2001/4016 , Y10T156/10
摘要： An oil gas separation membrane combines a gas permeable yet oil and temperature resistant bulk polymer membrane such as poly(tetrafluoroethylene) and poly(tetrafluoroethylene-co-hexafluoropropylene); a porous metal support such as sintered metal frit disk made with stainless steel, bronze or nickel; and an highly gas permeable adhesive that bonds firmly the bulk polymer membrane and the metal frit surface together. The adhesive is either a homogenous polymer that has desirable gas permeability, or a coalescent porous polymer particulates network. A gas sensor employing the oil gas separation membrane for detecting and monitoring fault gases of oil filled electrical equipment requires no mechanical wearing or moving part such as pump and valve and the gas sensor is operated normally under various temperature and pressure conditions.
摘要翻译：油气分离膜结合了透气但耐油和耐温的本体聚合物膜，例如聚（四氟乙烯）和聚（四氟乙烯 - 共 - 六氟丙烯）; 多孔金属支撑体，例如用不锈钢，青铜或镍制成的烧结金属玻璃料盘; 以及高度透气的粘合剂，其将本体聚合物膜和金属玻璃料表面牢固地粘合在一起。粘合剂是具有期望的气体渗透性的均匀聚合物，或聚结多孔聚合物颗粒网络。采用油气分离膜检测和监测充油电气设备故障气体的气体传感器不需要机械磨损或运动部件如泵和阀，气体传感器在各种温度和压力条件下都能正常运行。

7. 发明授权

US07986533B2 Shielding assembly and electronic device utilizing the same 有权
标题翻译：屏蔽组件和利用其的电子设备
公开(公告)号：US07986533B2
公开(公告)日：2011-07-26
申请号：US12437524
申请日：2009-05-07
申请人： Wen-Jia Ren , Xiao-Yan Qin
发明人： Wen-Jia Ren , Xiao-Yan Qin
IPC分类号： H05K9/00
CPC分类号： H05K9/0032
摘要： A shielding assembly comprises at least two shielding modules, each comprising a frame and a cover mounted on the frame. Each of the at least two covers comprises a plurality of engaging portions and a plurality of slots between each two adjacent engaging portions, and one portion of one of the at least two frames abuts one portion of another of the at least two frames. Each of the plurality of engaging portions of one of the at least two covers is received in a corresponding slot of another of the at least two covers to connect the at least two shielding covers to form a cover to reduce electromagnetic interference for an electronic components positioned on a circuit board.
摘要翻译：屏蔽组件包括至少两个屏蔽模块，每个屏蔽模块包括安装在框架上的框架和盖。所述至少两个盖中的每一个包括多个接合部分和在每两个相邻的接合部分之间的多个槽，并且所述至少两个框架中的一个的一部分邻接所述至少两个框架中的另一个的一部分。所述至少两个盖中的一个的多个接合部分中的每一个被接纳在所述至少两个盖中的另一个的相应槽中，以连接所述至少两个屏蔽盖以形成盖，以减少定位的电子部件的电磁干扰在电路板上。

8. 发明申请

US20100149780A1 SHIELDING ASSEMBLY AND ELECTRONIC DEVICE UTILIZING THE SAME 有权
标题翻译：屏蔽装置和使用该装置的电子装置
公开(公告)号：US20100149780A1
公开(公告)日：2010-06-17
申请号：US12437524
申请日：2009-05-07
申请人： WEN-JIA REN , XIAO-YAN QIN
发明人： WEN-JIA REN , XIAO-YAN QIN
IPC分类号： H05K9/00
CPC分类号： H05K9/0032
摘要： A shielding assembly comprises at least two shielding modules, each comprising a frame and a cover mounted on the frame. Each of the at least two covers comprises a plurality of engaging portions and a plurality of slots between each two adjacent engaging portions, and one portion of one of the at least two frames abuts one portion of another of the at least two frames. Each of the plurality of engaging portions of one of the at least two covers is received in a corresponding slot of another of the at least two covers to connect the at least two shielding covers to form a cover to reduce electromagnetic interference for an electronic components positioned on a circuit board.
摘要翻译：屏蔽组件包括至少两个屏蔽模块，每个屏蔽模块包括安装在框架上的框架和盖。所述至少两个盖中的每一个包括多个接合部分和在每两个相邻的接合部分之间的多个槽，并且所述至少两个框架中的一个的一部分邻接所述至少两个框架中的另一个的一部分。所述至少两个盖中的一个的多个接合部分中的每一个被接纳在所述至少两个盖中的另一个的相应槽中，以连接所述至少两个屏蔽盖以形成盖，以减少定位的电子部件的电磁干扰在电路板上。

9. 发明申请

US20080187963A1 Use of Lepa for Improving the Accuracy of Protein Synthesis in Vitro 审中-公开
标题翻译：使用Lepa提高体外蛋白质合成的准确性
公开(公告)号：US20080187963A1
公开(公告)日：2008-08-07
申请号：US11994211
申请日：2006-07-04
申请人： Knud H. Nierhaus , Yan Qin , Daniel N. Wilson
发明人： Knud H. Nierhaus , Yan Qin , Daniel N. Wilson
IPC分类号： C12P21/00 , C07H21/00
CPC分类号： C12P21/02 , C07K14/245
摘要： The present invention relates to methods, systems, compositions and kits for the synthesis of proteins in vitro, wherein the protein synthesis is carried out in the presence of the ribosomal factor LepA in order to significantly improve the accuracy of protein synthesis.
摘要翻译：本发明涉及体外合成蛋白质的方法，系统，组合物和试剂盒，其中蛋白质合成在核糖体因子LepA的存在下进行，以显着提高蛋白质合成的准确性。

10. 发明申请

US20100331413A1 Therapeutic Formulations Based on Asiatic Acid and Selected Salts Thereof 有权
标题翻译：基于亚洲酸及其选择盐的治疗配方
公开(公告)号：US20100331413A1
公开(公告)日：2010-12-30
申请号：US12811477
申请日：2009-01-08
申请人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
发明人： Ying Liu , Quanhai Liu , Yan Qin , Tong Wu , Zhiru Xu , Min-yu Liu , Fei Li , Yan Li , Michael J. Newman
IPC分类号： A61K31/19 , C07C62/32 , C07C233/00 , C07C69/74 , C07H13/02 , A61P11/00 , A61P3/10 , A61P1/00 , A61P17/06 , A61P19/02
CPC分类号： C07J63/008
摘要： A highly pure asiaticoside and a pharmaceutical grade asiatic acid can be prepared, along with salts of asiatic acid, for use in formulating therapeutic compositions that are suitable for treating arthritis, psoriasis and other inflammatory diseases, as well as pulmonary fibrosis, diabetic nephropathy, and other fibrotic diseases.
摘要翻译：可以制备高纯度积雪草苷和药物级积雪草酸以及积雪草酸盐，用于配制适合于治疗关节炎，牛皮癣和其它炎性疾病以及肺纤维化，糖尿病性肾病和其他纤维化疾病。

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