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1. 发明授权

US5549641A Atrial fibrillation type selective cardiovertor and method 失效
标题翻译：心房颤动型选择性心脏转移器及方法
公开(公告)号：US5549641A
公开(公告)日：1996-08-27
申请号：US331898
申请日：1994-10-31
申请人： Gregory M. Ayers , Clifton A. Alferness
发明人： Gregory M. Ayers , Clifton A. Alferness
IPC分类号： A61N1/362 , A61N1/39
CPC分类号： A61N1/3918 , A61N1/3622 , A61N1/3962 , A61N1/395
摘要： An atrial cardiovertor/defibrillator provides therapy to the atria corresponding to the type of atrial arrhythmia occurring in the atria of the heart. The atrial cardiovertor/defibrillator includes a memory for storing respective different criteria for each of different types of atrial arrhythmia, a sensor for sensing activity of at least one of the atria of the heart to provide an electrogram signal, and a cardiovertor for providing a corresponding therapy to the heart for each of the different types of atrial arrhythmia. The cardiovertor/defibrillator further includes an atrial arrhythmia detector responsive to the electrogram signal and the stored criteria for identifying one of the types of atrial arrhythmia to cause the cardiovertor to provide therapy to the heart corresponding to the identified atrial arrhythmia.
摘要翻译：房性心律转复/除纤颤器对心房心房发生心房心律失常类型的心房提供治疗。心房心律转移除颤器包括存储器，用于存储针对不同类型心房心律失常的各种不同的标准，用于感测心脏心房中的至少一个的活动以提供电描记图信号的传感器，以及用于提供对应的心律转换器治疗心脏每种不同类型的心房心律失常。心律转移除颤器进一步包括心律失常检测器，其响应于电描记图信号和存储的标准，用于识别心房心律失常的类型之一，以使心脏转移器向心脏对应于所确定的房性心律失常提供治疗。

2. 发明授权

US5486198A Atrial defibrillator and method for providing interval timing of successive intervals prior to cardioversion 失效
标题翻译：心房除颤器和在心脏复律之前提供连续间隔的间隔时间的方法
公开(公告)号：US5486198A
公开(公告)日：1996-01-23
申请号：US289701
申请日：1994-08-12
申请人： Gregory M. Ayers , Clifton A. Alferness , Harley G. White
发明人： Gregory M. Ayers , Clifton A. Alferness , Harley G. White
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3918 , A61N1/395 , A61N1/3987
摘要： An atrial defibrillator and method provides cardioverting electrical energy to the atria of a human heart after timing successive R to R intervals. A detector detects ventricular activations of the heart and a timer times intervals between immediately successive ventricular activations. A cardiovertor applies cardioverting electrical energy to the atria of the heart when a second time interval between a third ventricular activation and a second ventricular activation immediately preceding the third ventricular activation satisfies a predetermined criteria with respect to a first time interval between the second ventricular activation and a first ventricular activation immediately preceding the second ventricular activation.
摘要翻译：心房除颤器和方法在定时连续的R至R间隔之后向心脏心房提供心律转复的电能。检测器检测心脏的心室激活，并且定时器在紧接着的心室激活之间进行时间间隔。当在第三心室激活之前的第三心室激活和第二心室激活之间的第二时间间隔相对于第二心室激活和第二心室激活之间的第一时间间隔满足预定标准时，心律转换器将心脏转换电能施加到心脏心房在第二次心室激活之前的第一次心室激活。

3. 发明授权

US5403353A Post-heart surgery cardioverting system and method 失效
标题翻译：心脏手术心脏转复系统及方法
公开(公告)号：US5403353A
公开(公告)日：1995-04-04
申请号：US100492
申请日：1993-07-30
申请人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
发明人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
IPC分类号： A61N1/05 , A61N1/362 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3918 , A61N1/05 , A61N1/0587 , A61N1/362 , A61N1/39 , A61N1/395
摘要： A post-surgical cardioverting system and method applies cardioverting electrical energy to the atria of the heart of a post-surgical heart patient. The system includes a first lead including a first elongated electrode having a proximal end and a distal end, a second lead including a second elongated electrode having a proximal end and a distal end, and sutures for releasably anchoring the distal ends of the first and second electrodes to the pericardium and disposing the first and second electrodes along the pericardium overlying the right and left atria respectively. A non-implantable cardiovertor is coupled to the first and second leads for applying the cardioverting electrical energy to the first and second electrodes. When cardioversion is no longer required, the first and second leads may be pulled out of the patient's chest.
摘要翻译：手术后心脏转复系统和方法将心脏转移电能应用于手术后心脏病人心脏的心房。该系统包括第一引线，其包括具有近端和远端的第一细长电极，第二引线包括具有近端和远端的第二细长电极，以及用于可释放地锚固第一和第二末端的缝合线的缝合线电极到心包，并且分别沿着包围右心房和左心房的心包布置第一和第二电极。非植入式心律转换器耦合到第一和第二引线，用于将心电转换电能施加到第一和第二电极。当不再需要心脏复律时，可以将第一和第二引线从病人的胸部拉出。

4. 发明授权

US5766224A Temporary, post-heart surgery cardioverting and pacing system and lead systems for use therein 失效
标题翻译：临床，心脏手术后心脏转复和起搏系统及其使用的引导系统
公开(公告)号：US5766224A
公开(公告)日：1998-06-16
申请号：US627688
申请日：1996-04-02
申请人： Clifton A. Alferness , John M. Adams , Gregory M. Ayers , Hugo X. Gonzalez
发明人： Clifton A. Alferness , John M. Adams , Gregory M. Ayers , Hugo X. Gonzalez
IPC分类号： A61N1/05 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/0587
摘要： A post-surgical atrial cardioverting, atrial pacing, and ventricular pacing system and lead system provides for cardioverting the atria, pacing the atria, and/or pacing the ventricles of the heart of a post-surgical heart patient. The system includes a first lead and a second lead providing a pair of atrial cardioverting electrodes, an atrial pacing electrode, and a ventricular pacing electrode. The electrodes are electrically isolated from each other. The system further includes at least one anchor releasably disposing the electrodes beneath the skin of the patient with each atrial cardioverting electrode electrically contacting a respective given one of the atria, the atrial pacing electrode electrically contacting one of the atria, and the ventricular pacing electrode electrically contacting a ventricle. The system further includes at least one of an external cardiovertor coupled to the cardioverting electrodes for cardioversion, an external atrial pacer coupled to the atrial pacing electrode and one of the atrial cardioverting electrodes for pacing the atria, and an external ventricular pacer coupled to the ventricular pacing electrode and one of the atrial cardioverting electrodes for pacing the ventricles.
摘要翻译：手术后心房心律转复，心房起搏和心室起搏系统和牵引系统提供心脏转移心房，起搏心房和/或起搏手术后心脏病人心脏的心室。该系统包括提供一对心房心脏转复电极，心房起搏电极和心室起搏电极的第一引线和第二引线。电极彼此电隔离。所述系统还包括至少一个锚定器，其可释放地将电极设置在患者皮肤下方，每个心房心脏转复电极与相应的心房起搏器电气接触，心房起搏电极与心房起搏器电气接触，接触心室。该系统还包括耦合到用于心脏复律的复律电极的外部心脏转换器中的至少一个，耦合到心房起搏电极的外部心房起搏器和用于起搏心房的心房心律转换电极之一和与心室联接的外部心室起搏器起搏电极和心房心律转复电极之一用于起搏心室。

5. 再颁专利

USRE35779E Post-heart surgery cardioverting system and method 失效
公开(公告)号：USRE35779E
公开(公告)日：1998-04-28
申请号：US608410
申请日：1996-02-28
申请人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
发明人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
IPC分类号： A61N1/05 , A61N1/362 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3918 , A61N1/05 , A61N1/0587 , A61N1/362 , A61N1/39 , A61N1/395
摘要： A post-surgical cardioverting system and method applies cardioverting electrical energy to the atria of the heart of a post-surgical heart patient. The system includes a first lead including a first elongated electrode having a proximal end and a distal end, a second lead including a second elongated electrode having a proximal end and a distal end, and sutures for releasably anchoring the distal ends of the first and second electrodes to the pericardium and disposing the first and second electrodes along the pericardium overlying the right and left atria respectively. A non-implantable cardiovertor is coupled to the first and second leads for applying the cardioverting electrical energy to the first and second electrodes. When cardioversion is no longer required, the first and second leads may be pulled out of the patient's chest.

6. 发明授权

US10064615B2 Tissue fixation devices and a transoral endoscopic gastroesophageal flap valve restoration device and assembly using same 有权
公开(公告)号：US10064615B2
公开(公告)日：2018-09-04
申请号：US13604276
申请日：2012-09-05
申请人： Steve G. Baker , Brett J. Carter , Stefan J. M. Kraemer , Clifton A. Alferness , John M. Adams
发明人： Steve G. Baker , Brett J. Carter , Stefan J. M. Kraemer , Clifton A. Alferness , John M. Adams
IPC分类号： A61B17/04 , A61B17/064 , A61B17/068 , A61B17/00
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/068 , A61B2017/00827 , A61B2017/0409 , A61B2017/0414 , A61B2017/0419
摘要： Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together. The fasteners include a first member, a second member, and a connecting member extending between the first and second members. The first and second members are substantially parallel to each other. The fasteners may be deployed in limited spaces and in various applications including the restoration of a gastroesophageal flap valve.

7. 发明申请

US20170014132A9 TRANSESOPHAGEAL GASTRIC REDUCTION METHOD AND DEVICE FOR REDUCING THE SIZE OF A PREVIOUSLY FORMED GASTRIC REDUCTION POUCH 审中-公开
标题翻译：用于减少先前形成的减少气泡的尺寸的透气性减少方法和装置
公开(公告)号：US20170014132A9
公开(公告)日：2017-01-19
申请号：US13726525
申请日：2012-12-24
申请人： Steve G. BAKER , Raymond Michael Wolniewicz, III , Sean Totten , Clifton A. Alferness , Scott Harshman
发明人： Steve G. BAKER , Raymond Michael Wolniewicz, III , Sean Totten , Clifton A. Alferness , Scott Harshman
IPC分类号： A61B17/11 , A61B19/00
CPC分类号： A61B17/11 , A61B17/0401 , A61B34/30 , A61B90/00 , A61B2017/00349 , A61B2017/00818 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/306 , A61F5/0079 , A61F5/0086
摘要： A gastric reduction pouch of a stomach is formed by gathering stomach tissue circumferentially from within the stomach to form a reduced diameter stomach section. A plurality of fasteners are deployed within the gathered stomach tissue to maintain the reduced diameter stomach portion. The gathering step may include folding the stomach tissue to produce a plurality of stomach tissue folds. A device is disclosed that is particularly adapted to permit such gastric reduction of a previously formed gastric reduction pouch.
摘要翻译：通过从胃内周向聚集胃部组织形成缩小的胃部部分来形成胃的胃减压袋。多个紧固件部署在聚集的胃组织内以保持直径缩小的胃部分。收集步骤可以包括折叠胃组织以产生多个胃组织褶皱。公开了一种特别适于允许先前形成的胃减压袋的胃部还原的装置。

8. 发明授权

US08956374B2 Shockwave balloon catheter system 有权
公开(公告)号：US08956374B2
公开(公告)日：2015-02-17
申请号：US13049199
申请日：2011-03-16
申请人： Daniel Hawkins , Clifton A. Alferness , John M. Adams
发明人： Daniel Hawkins , Clifton A. Alferness , John M. Adams
IPC分类号： A61B17/22 , A61B17/225 , A61B17/3207
CPC分类号： A61B17/22022 , A61B17/2202 , A61B17/22029 , A61B17/2251 , A61B17/320725 , A61B2017/22001 , A61B2017/22021 , A61B2017/22024 , A61B2017/22025 , A61B2017/22038 , A61B2017/22058 , A61B2017/22061 , A61B2017/22062
摘要： A system for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.

9. 发明授权

US08956371B2 Shockwave balloon catheter system 有权
标题翻译：冲击波球导管系统
公开(公告)号：US08956371B2
公开(公告)日：2015-02-17
申请号：US12482995
申请日：2009-06-11
申请人： Daniel Hawkins , Clifton A. Alferness , John M. Adams
发明人： Daniel Hawkins , Clifton A. Alferness , John M. Adams
IPC分类号： A61B17/22 , A61B17/225 , A61B17/3207
CPC分类号： A61B17/22022 , A61B17/2202 , A61B17/22029 , A61B17/2251 , A61B17/320725 , A61B2017/22001 , A61B2017/22021 , A61B2017/22024 , A61B2017/22025 , A61B2017/22038 , A61B2017/22058 , A61B2017/22061 , A61B2017/22062
摘要： A system for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.
摘要翻译：用于破坏体腔内的障碍物的系统包括导管，其包括细长的载体，围绕载体与其密封的关系的气囊，所述气囊被布置成在其中容纳使气囊膨胀的流体，以及包括至少一个电极的电弧发生器气球在气球内形成机械冲击波。该系统还包括向电弧发生器提供电能的电源。

10. 发明授权

US08956319B2 One-way valve devices for anchored implantation in a lung 有权
标题翻译：用于锚定植入肺部的单向阀装置
公开(公告)号：US08956319B2
公开(公告)日：2015-02-17
申请号：US13554987
申请日：2012-07-20
申请人： David H. Dillard , Hugo X. Gonzalez , Seung Yi , Lauri J. DeVore , Mia Park , Dean T. Corcoran , Jenni Rimbaugh , Clifton A. Alferness
发明人： David H. Dillard , Hugo X. Gonzalez , Seung Yi , Lauri J. DeVore , Mia Park , Dean T. Corcoran , Jenni Rimbaugh , Clifton A. Alferness
IPC分类号： A61M5/00 , A61B17/12 , A61F2/24 , A61F2/04
CPC分类号： A61B17/12104 , A61B17/12172 , A61B2017/00809 , A61F2/24 , A61F2002/043
摘要： An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.
摘要翻译：将支气管内装置放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。该装置包括支撑结构，由支撑结构承载的阻塞构件，其通过防止空气被吸入肺部而减少对肺部的通气，以及由支撑结构承载的至少一个锚固件，其将阻塞装置锚定在内部空气通道。锚固件可以通过穿孔或摩擦接合空气通道壁，包括尺寸适于限制空气通道壁的刺穿的止挡件，并且可以从空气通道释放以去除支气管内装置。锚固件可以由支撑结构的周边部分或支撑结构的中心部分承载。阻塞构件可以是单向阀。

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