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1. 发明授权

US5766224A Temporary, post-heart surgery cardioverting and pacing system and lead systems for use therein 失效
标题翻译：临床，心脏手术后心脏转复和起搏系统及其使用的引导系统
公开(公告)号：US5766224A
公开(公告)日：1998-06-16
申请号：US627688
申请日：1996-04-02
申请人： Clifton A. Alferness , John M. Adams , Gregory M. Ayers , Hugo X. Gonzalez
发明人： Clifton A. Alferness , John M. Adams , Gregory M. Ayers , Hugo X. Gonzalez
IPC分类号： A61N1/05 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/0587
摘要： A post-surgical atrial cardioverting, atrial pacing, and ventricular pacing system and lead system provides for cardioverting the atria, pacing the atria, and/or pacing the ventricles of the heart of a post-surgical heart patient. The system includes a first lead and a second lead providing a pair of atrial cardioverting electrodes, an atrial pacing electrode, and a ventricular pacing electrode. The electrodes are electrically isolated from each other. The system further includes at least one anchor releasably disposing the electrodes beneath the skin of the patient with each atrial cardioverting electrode electrically contacting a respective given one of the atria, the atrial pacing electrode electrically contacting one of the atria, and the ventricular pacing electrode electrically contacting a ventricle. The system further includes at least one of an external cardiovertor coupled to the cardioverting electrodes for cardioversion, an external atrial pacer coupled to the atrial pacing electrode and one of the atrial cardioverting electrodes for pacing the atria, and an external ventricular pacer coupled to the ventricular pacing electrode and one of the atrial cardioverting electrodes for pacing the ventricles.
摘要翻译：手术后心房心律转复，心房起搏和心室起搏系统和牵引系统提供心脏转移心房，起搏心房和/或起搏手术后心脏病人心脏的心室。该系统包括提供一对心房心脏转复电极，心房起搏电极和心室起搏电极的第一引线和第二引线。电极彼此电隔离。所述系统还包括至少一个锚定器，其可释放地将电极设置在患者皮肤下方，每个心房心脏转复电极与相应的心房起搏器电气接触，心房起搏电极与心房起搏器电气接触，接触心室。该系统还包括耦合到用于心脏复律的复律电极的外部心脏转换器中的至少一个，耦合到心房起搏电极的外部心房起搏器和用于起搏心房的心房心律转换电极之一和与心室联接的外部心室起搏器起搏电极和心房心律转复电极之一用于起搏心室。

2. 发明授权

US5403353A Post-heart surgery cardioverting system and method 失效
标题翻译：心脏手术心脏转复系统及方法
公开(公告)号：US5403353A
公开(公告)日：1995-04-04
申请号：US100492
申请日：1993-07-30
申请人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
发明人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
IPC分类号： A61N1/05 , A61N1/362 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3918 , A61N1/05 , A61N1/0587 , A61N1/362 , A61N1/39 , A61N1/395
摘要： A post-surgical cardioverting system and method applies cardioverting electrical energy to the atria of the heart of a post-surgical heart patient. The system includes a first lead including a first elongated electrode having a proximal end and a distal end, a second lead including a second elongated electrode having a proximal end and a distal end, and sutures for releasably anchoring the distal ends of the first and second electrodes to the pericardium and disposing the first and second electrodes along the pericardium overlying the right and left atria respectively. A non-implantable cardiovertor is coupled to the first and second leads for applying the cardioverting electrical energy to the first and second electrodes. When cardioversion is no longer required, the first and second leads may be pulled out of the patient's chest.
摘要翻译：手术后心脏转复系统和方法将心脏转移电能应用于手术后心脏病人心脏的心房。该系统包括第一引线，其包括具有近端和远端的第一细长电极，第二引线包括具有近端和远端的第二细长电极，以及用于可释放地锚固第一和第二末端的缝合线的缝合线电极到心包，并且分别沿着包围右心房和左心房的心包布置第一和第二电极。非植入式心律转换器耦合到第一和第二引线，用于将心电转换电能施加到第一和第二电极。当不再需要心脏复律时，可以将第一和第二引线从病人的胸部拉出。

3. 再颁专利

USRE35779E Post-heart surgery cardioverting system and method 失效
公开(公告)号：USRE35779E
公开(公告)日：1998-04-28
申请号：US608410
申请日：1996-02-28
申请人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
发明人： Clifton A. Alferness , Gregory M. Ayers , Jerry C. Griffin , Kenneth R. Infinger
IPC分类号： A61N1/05 , A61N1/362 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3918 , A61N1/05 , A61N1/0587 , A61N1/362 , A61N1/39 , A61N1/395
摘要： A post-surgical cardioverting system and method applies cardioverting electrical energy to the atria of the heart of a post-surgical heart patient. The system includes a first lead including a first elongated electrode having a proximal end and a distal end, a second lead including a second elongated electrode having a proximal end and a distal end, and sutures for releasably anchoring the distal ends of the first and second electrodes to the pericardium and disposing the first and second electrodes along the pericardium overlying the right and left atria respectively. A non-implantable cardiovertor is coupled to the first and second leads for applying the cardioverting electrical energy to the first and second electrodes. When cardioversion is no longer required, the first and second leads may be pulled out of the patient's chest.

4. 发明授权

US5549641A Atrial fibrillation type selective cardiovertor and method 失效
标题翻译：心房颤动型选择性心脏转移器及方法
公开(公告)号：US5549641A
公开(公告)日：1996-08-27
申请号：US331898
申请日：1994-10-31
申请人： Gregory M. Ayers , Clifton A. Alferness
发明人： Gregory M. Ayers , Clifton A. Alferness
IPC分类号： A61N1/362 , A61N1/39
CPC分类号： A61N1/3918 , A61N1/3622 , A61N1/3962 , A61N1/395
摘要： An atrial cardiovertor/defibrillator provides therapy to the atria corresponding to the type of atrial arrhythmia occurring in the atria of the heart. The atrial cardiovertor/defibrillator includes a memory for storing respective different criteria for each of different types of atrial arrhythmia, a sensor for sensing activity of at least one of the atria of the heart to provide an electrogram signal, and a cardiovertor for providing a corresponding therapy to the heart for each of the different types of atrial arrhythmia. The cardiovertor/defibrillator further includes an atrial arrhythmia detector responsive to the electrogram signal and the stored criteria for identifying one of the types of atrial arrhythmia to cause the cardiovertor to provide therapy to the heart corresponding to the identified atrial arrhythmia.
摘要翻译：房性心律转复/除纤颤器对心房心房发生心房心律失常类型的心房提供治疗。心房心律转移除颤器包括存储器，用于存储针对不同类型心房心律失常的各种不同的标准，用于感测心脏心房中的至少一个的活动以提供电描记图信号的传感器，以及用于提供对应的心律转换器治疗心脏每种不同类型的心房心律失常。心律转移除颤器进一步包括心律失常检测器，其响应于电描记图信号和存储的标准，用于识别心房心律失常的类型之一，以使心脏转移器向心脏对应于所确定的房性心律失常提供治疗。

5. 发明授权

US5486198A Atrial defibrillator and method for providing interval timing of successive intervals prior to cardioversion 失效
标题翻译：心房除颤器和在心脏复律之前提供连续间隔的间隔时间的方法
公开(公告)号：US5486198A
公开(公告)日：1996-01-23
申请号：US289701
申请日：1994-08-12
申请人： Gregory M. Ayers , Clifton A. Alferness , Harley G. White
发明人： Gregory M. Ayers , Clifton A. Alferness , Harley G. White
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3918 , A61N1/395 , A61N1/3987
摘要： An atrial defibrillator and method provides cardioverting electrical energy to the atria of a human heart after timing successive R to R intervals. A detector detects ventricular activations of the heart and a timer times intervals between immediately successive ventricular activations. A cardiovertor applies cardioverting electrical energy to the atria of the heart when a second time interval between a third ventricular activation and a second ventricular activation immediately preceding the third ventricular activation satisfies a predetermined criteria with respect to a first time interval between the second ventricular activation and a first ventricular activation immediately preceding the second ventricular activation.
摘要翻译：心房除颤器和方法在定时连续的R至R间隔之后向心脏心房提供心律转复的电能。检测器检测心脏的心室激活，并且定时器在紧接着的心室激活之间进行时间间隔。当在第三心室激活之前的第三心室激活和第二心室激活之间的第二时间间隔相对于第二心室激活和第二心室激活之间的第一时间间隔满足预定标准时，心律转换器将心脏转换电能施加到心脏心房在第二次心室激活之前的第一次心室激活。

6. 发明授权

US5814081A Atrial flutter cardioverter and method 失效
标题翻译：心房扑动心律转换器及方法
公开(公告)号：US5814081A
公开(公告)日：1998-09-29
申请号：US835169
申请日：1997-04-07
申请人： Gregory M. Ayers , John M. Adams
发明人： Gregory M. Ayers , John M. Adams
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/395
摘要： An implantable atrial defibrillator includes a lead system having a plurality of electrodes to deliver a cardioverting pulse to atria of a heart, for sensing A waves of the heart, and for sensing R waves of the heart. A first detector detects the A waves sensed by the lead system and a second detector detects the R waves sensed by the lead system. An inhibit stage defines an inhibit time period responsive to each detected R wave and an output provides the cardioverting pulse to the lead system responsive to an A wave being detected. The inhibit stage precludes provision of the cardioverting pulse during each inhibit time period.
摘要翻译：可植入心房除颤器包括引导系统，该引导系统具有多个电极，用于将心律转换脉冲输送到心脏的心房，用于感测心脏的波浪，并用于感测心脏的R波。第一检测器检测由引导系统感测的A波，第二检测器检测由引导系统感测的R波。禁止级定义响应于每个检测到的R波的禁止时间周期，并且输出响应于检测到的A波而将引导系统提供心跳转换脉冲。禁止阶段排除了在每个禁止时间段期间提供的复律脉冲。

7. 发明授权

US5350402A Atrial defibrillator and method for providing T wave detection and interval timing prior to cardioversion 失效
标题翻译：心房除颤器和在心脏复律前提供T波检测和间隔时间的方法
公开(公告)号：US5350402A
公开(公告)日：1994-09-27
申请号：US67688
申请日：1993-05-26
申请人： Kenneth R. Infinger , Gregory M. Ayers , Darrell O. Wagner , John M. Adams
发明人： Kenneth R. Infinger , Gregory M. Ayers , Darrell O. Wagner , John M. Adams
IPC分类号： A61N1/365 , A61N1/362 , A61N1/39
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395 , A61N1/3987
摘要： An implantable atrial defibrillator and method provides cardioverting electrical energy to the atria of a human heart in need of cardioversion. The atrial defibrillator includes a first detector for detecting R waves of the heart, a second detector for detecting T waves of the heart, and a third detector for detecting atrial activity of the heart. An atrial fibrillation detector is responsive to the third detector for determining when the atria of the heart are in need of cardioversion. A cardioverting stage applies the cardioverting electrical energy to the atria of the heart when the atria of the heart are in need of cardioversion, after the second detector detects a T wave, and in timed relation to an R wave detected by the first detector after the detected T wave is completed. The atrial defibrillator includes a timer for timing a predetermined delay time after the T wave is detected, which delay time must be completed before the atria are cardioverted in timed relation to a detected R wave to assure that the detected T wave is completed.
摘要翻译：可植入心房除颤器和方法为需要心脏复律的心脏心房提供心律转复的电能。心房除颤器包括用于检测心脏的R波的第一检测器，用于检测心脏的T波的第二检测器，以及用于检测心脏的心房活动的第三检测器。心房颤动检测器响应于第三检测器，用于确定心脏心房何时需要心脏复律。当心脏的心房需要心脏复律时，在第二检测器检测到T波之后，以及在与第一检测器之后检测到的R波的定时关系中，心脏转换的电能将心脏转换的能量应用于心脏的心房检测到T波完成。心房除颤器包括：定时器，用于在检测到T波之后定时预定的延迟时间，该延迟时间必须在心跳与检测的R波的定时关系转换之前完成，以确保检测到的T波完成。

8. 发明授权

US5674250A Atrial defibrillator and method for providing adaptive control of defibrillator output voltage 失效
标题翻译：心房除颤器和提供自适应控制除颤器输出电压的方法
公开(公告)号：US5674250A
公开(公告)日：1997-10-07
申请号：US641100
申请日：1996-04-29
申请人： Paul E. de Coriolis , Gregory M. Ayers
发明人： Paul E. de Coriolis , Gregory M. Ayers
IPC分类号： A61N1/39
CPC分类号： A61N1/3943 , A61N1/395
摘要： An implantable atrial defibrillator provides adaptive output voltage control. An atrial cardiovertor is responsive to an atrial fibrillation detector for applying a cardioverting voltage having a magnitude to the atria of a heart when the atria are in need of cardioversion. A memory stores data associated with each such voltage application. A computation stage computes from the stored data a percentage of success which is compared to lower and upper limits. The output voltage is incremented or decrement based upon the comparison. The output voltage may further be maintained within a fixed preselected voltage range.
摘要翻译：可植入心房除颤器提供自适应输出电压控制。心房心律转换器响应于心房颤动检测器，当心房需要心脏复律时，将心律转复电压施加到心脏心房的大小。存储器存储与每个这样的电压应用相关联的数据。计算阶段根据存储数据计算与下限和上限进行比较的成功百分比。基于比较，输出电压递增或递减。输出电压可以进一步保持在固定的预选电压范围内。

9. 发明授权

US5405375A Combined mapping, pacing, and defibrillating catheter 失效
标题翻译：组合贴图，起搏和除颤导管
公开(公告)号：US5405375A
公开(公告)日：1995-04-11
申请号：US184375
申请日：1994-01-21
申请人： Gregory M. Ayers , Joseph M. Smith
发明人： Gregory M. Ayers , Joseph M. Smith
IPC分类号： A61N1/04 , A61N1/05
CPC分类号： A61N1/0563 , A61N1/056
摘要： A catheter insertable into a body provides for both sensing electrical activity of the heart at localized locations of the heart and defibrillating the heart when defibrillation is required. The catheter includes a plurality of connectors at the proximal end and a plurality of electrodes disposed along the catheter at the distal end. The plurality of electrodes includes a first plurality of electrodes and a second plurality of electrodes. The first plurality of electrodes are coupled together and to a given one of the plurality of connectors. Each of the second plurality of electrodes is coupled to a respective different one of the plurality of connectors. The first plurality of electrodes provide for defibrillating the heart and the second plurality of electrodes provide for sensing electrical activity of the heart at localized locations of the heart.
摘要翻译：可插入体内的导管可以在需要除颤时在心脏的局部位置感测心脏的电活动并去除心脏。导管包括在近端处的多个连接器以及在远端处沿导管设置的多个电极。多个电极包括第一多个电极和第二多个电极。第一组多个电极耦合在一起并连接到多个连接器中的给定的一个。第二多个电极中的每一个耦合到多个连接器中的相应不同的一个。第一组多个电极提供去纤颤心脏，并且第二多个电极提供用于感测心脏在心脏局部位置处的电活动。

10. 发明授权

US5395373A Atrial defibrillator and method for setting energy threshold values 失效
标题翻译：心房除颤器和设定能量阈值的方法
公开(公告)号：US5395373A
公开(公告)日：1995-03-07
申请号：US1454
申请日：1993-01-07
申请人： Gregory M. Ayers
发明人： Gregory M. Ayers
IPC分类号： A61N1/38 , A61N1/39
CPC分类号： A61N1/385 , A61N1/3943 , A61N1/395
摘要： An implantable atrial defibrillator cardioverts the atria of a patient's heart and determines the quantity of cardioverting electrical energy required for cardioverting the atria of the patient. The atrial defibrillator includes a detector for detecting atrial activity of the heart and an atrial fibrillation detector for determining when the atria of the heart are in fibrillation. A delivery stage is selectively operable in a test mode for applying fibrillation inducing electrical energy to the atria when the atria are not in fibrillation for inducing fibrillation. When fibrillation is induced, the delivery stage repeatedly applies test cardioversion electrical energy to the atria until the atria are cardioverted. Thereafter, a value indicative of the quantity of the test cardioversion energy last applied to the atria is stored for future reference when the atrial defibrillator is in a normal operating mode.
摘要翻译：可植入心房除颤器对心脏的心房进行心脏转复，并确定心脏转移患者心房所需的心脏转移电能的量。心房除颤器包括用于检测心脏的心房活动的检测器和心房颤动检测器，用于确定心脏的心房何时起颤。递送阶段可选择性地在测试模式下操作，用于当心房不起颤动以诱导原纤维颤动时，向心房施加诱发电能的原纤维。当诱发原纤维化时，输送阶段将心电复查电能重复地应用于心房直到心房被转复。此后，当心房除颤器处于正常操作模式时，存储指示最后施加到心房的测试复律能量的值的值以供将来参考。

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