专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07419998B2 Therapeutic methods and compositions involving isoflavones 失效
公开(公告)号：US07419998B2
公开(公告)日：2008-09-02
申请号：US11024512
申请日：2004-12-28
申请人： Graham Edmund Kelly , George Eustace Joannou
发明人： Graham Edmund Kelly , George Eustace Joannou
IPC分类号： A61K31/40 , A61K31/35 , A61K31/335 , A61K31/24 , A61K31/22 , A61K31/08 , A61K31/415 , A61K31/05
CPC分类号： A61K8/498 , A61K8/35 , A61K8/492 , A61K31/12 , A61K31/352 , A61K31/353 , A61K31/355 , A61K31/40 , A61K31/404 , A61K31/405 , A61K31/47 , A61K31/4745 , A61K2800/522 , A61Q7/00 , A61Q19/00 , A61Q19/08 , C07C45/46 , C07C45/673 , C12P7/26 , C12P17/04 , C12P17/10 , A61K2300/00 , C07C49/83 , C07C49/84
摘要： Therapeutic methods of treatment, compositions and foodstuffs are described which contain isoflavone compounds described by general formula (I), in which Z is H, R1 is H, or RACO where RA is C1-10alkyl or an amino acid, R2 is H, OH, or ORB where RB is an amino acid, or CORA where RA is as previously defined, W is H, A is H or OH, and B is selected from (a), (b), (c), or W is H, and A and B taken together form a six-membered ring selected from (d), or W, A and B taken with the groups with which they are associated comprise (e), or W and A taken together with the groups with which they are associated comprise (f) and B is (g) wherein R3 is H, CORA where RA is as previously defined, CO2RC where RC is C1-10alkyl, or CORB where RB is as previously defined, R4 is H, CORD where RD is H, OH, C1-10alkyl or an amino acid, CO2RC where RC is as previously defined, CORE where RE is H. C1-10alkyl or an amino acid, COOH, CORC where RC is as previously defined, or CONHRE where RE is as previously defined, R5 is H, CORC where RC is as previously defined, or CORCORE where RC and RE are as previously defined, and where the two R5 groups are attached to the same group they are the same or different, R6 is H or hydroxy C1-10alkyl, X is preferably O, but may be N or S, and Y is (h) where R7 is H, or C1-10alkyl.

2. 发明授权

US07714151B2 Aminated isoflavonoid derivatives and uses thereof 失效
标题翻译：氨基异黄酮衍生物及其用途
公开(公告)号：US07714151B2
公开(公告)日：2010-05-11
申请号：US10532074
申请日：2003-11-03
申请人： Graham Edmund Kelly , Andrew Heaton , Jane Faragalla , John Bremner
发明人： Graham Edmund Kelly , Andrew Heaton , Jane Faragalla , John Bremner
IPC分类号： C07D311/02
CPC分类号： A61K31/352 , C07D311/68
摘要： Aminated isoflavonoid synthesized by aminating the 4-keto group of isoflavanone and isoflavanone ring systems, pharmaceutical compositions containing same and uses thereof as therapeutic agents.
摘要翻译：通过胺化异黄酮和异黄烷酮环系的4-酮基合成的氨基异黄酮，含有其的药物组合物和其用作治疗剂。

3. 发明授权

US07648968B2 Methods of treating dermal ulcers using glucans 失效
标题翻译：使用葡聚糖治疗皮肤溃疡的方法
公开(公告)号：US07648968B2
公开(公告)日：2010-01-19
申请号：US11499904
申请日：2006-08-04
申请人： Graham Edmund Kelly
发明人： Graham Edmund Kelly
IPC分类号： A61K31/716 , A61K31/717 , A61K31/718 , A61K31/721 , A61K47/00
CPC分类号： A61Q17/04 , A61K8/73 , A61K31/716 , A61L26/0023 , A61Q19/004 , A61Q19/08 , C08B37/0024 , C12P19/04 , Y10S514/925 , Y10S514/928 , C08L5/00
摘要： The present invention is directed to methods of using glucan compositions, comprising water insoluble microparticulate glucans, in the treatment of dermal ulcers. The water insoluble microparticulate glucans used in the compositions comprise branched β-(1,3)(1,6) glucan. The glucan compositions used in the present invention are essentially free of unbranched β-(1,3)(1,6) glucan and non-glucan components.
摘要翻译：本发明涉及使用包含水不溶性微粒葡聚糖的葡聚糖组合物在治疗皮肤溃疡中的方法。组合物中使用的水不溶性微粒葡聚糖包含支链β-（1,3）（1,6）葡聚糖。用于本发明的葡聚糖组合物基本上不含无支化的β-（1,3）（1,6）葡聚糖和非葡聚糖组分。

4. 发明授权

US07202273B2 Therapeutic methods and compositions involving isoflavones 失效
公开(公告)号：US07202273B2
公开(公告)日：2007-04-10
申请号：US10176762
申请日：2002-06-21
申请人： Graham Edmund Kelly , George Eustace Joannou
发明人： Graham Edmund Kelly , George Eustace Joannou
IPC分类号： A61K31/35 , A61K31/045 , A61K31/445
CPC分类号： A61K8/498 , A61K8/35 , A61K8/492 , A61K31/12 , A61K31/352 , A61K31/353 , A61K31/355 , A61K31/40 , A61K31/404 , A61K31/405 , A61K31/47 , A61K31/4745 , A61K2800/522 , A61Q7/00 , A61Q19/00 , A61Q19/08 , C07C45/46 , C07C45/673 , C12P7/26 , C12P17/04 , C12P17/10 , A61K2300/00 , C07C49/83 , C07C49/84
摘要： Therapeutic methods of treatment, compositions and foodstuffs are described which contain isoflavone compounds described by general formula (1), in which Z is H, R1 is H, or RACO where RA is C1-10alkyl or an amino acid, R2 is H, OH, or ORB where RB is an amino acid, or CORA where RA is as previously defined, W is H, A is H or OH, and B is selected from (a), (b), (c), or W is H, and A and B taken together form a six-membered ring selected from (d), or W, A and B taken with the groups with which they are associated comprise (e), or W and A taken together with the groups with which they are associated comprise (f) and B is (g) wherein R3 is H, CORA where RA is as previously defined, CO2Rc where RC is C1-10alkyl, or CORB where RB is as previously defined, R4 is H, CORD where RD is H, OH, C1-10alkyl or an amino acid, CO2RC where RC is as previously defined, CORE where RE is H, C1-10alkyl or an amino acid, COOH, CORC where RC is as previously defined, or CONHRE where RE is as previously defined, R5 is H, CORC where RC is as previously defined, or CORCORE where RC and RE are as previously defined, and where the two R5 groups are attached to the same group they are the same or different, R6 is H or hydroxy C1-10alkyl, X is preferably O, but may be N or S, and Y is (h) where R7 is H, or C1-10alkyl

5. 发明授权

US06562380B1 Methods for treating or reducing prediposition to breast cancer, pre-menstrual syndrome or symptoms associated with menopause by administration of phyto-estrogen 失效
标题翻译：通过施用植物雌激素治疗或减少经前综合征或与更年期相关的症状的倾向的方法
公开(公告)号：US06562380B1
公开(公告)日：2003-05-13
申请号：US08910837
申请日：1997-08-13
申请人： Graham Edmund Kelly
发明人： Graham Edmund Kelly
IPC分类号： A61K3578
CPC分类号： A61K31/35 , A23L11/05 , A23L11/07 , A23L33/11 , A61K31/353 , A61K31/7048 , A61K36/185 , A61K36/48 , A61K38/08 , A61K2300/00
摘要： Phyto-estrogen-containing health supplement compositions containing any two or more of Genistein, Daidzein, Formononetin and Biochanin A, or the natural glycosides thereof are administered for treating or reducing predisposition to breast cancer, pre-menstrual syndrome or symptoms of menopause.
摘要翻译：给予含有染料木黄酮，大豆黄素，角叉菜胶蛋白素和鹰嘴豆素A或其天然糖苷中任意两种以上的含植物雌激素的健康补充剂组合物，用于治疗或减少乳腺癌的易感性，月经前期症状或更年期症状。

6. 发明授权

US06455032B1 Composition and method for protecting skin from UV induced immunosuppression and skin damage 有权
标题翻译：用于保护皮肤免受UV诱导的免疫抑制和皮肤损伤的组合物和方法
公开(公告)号：US06455032B1
公开(公告)日：2002-09-24
申请号：US09582317
申请日：2000-06-23
申请人： Graham Edmund Kelly , Alan James Husband
发明人： Graham Edmund Kelly , Alan James Husband
IPC分类号： A61K742
CPC分类号： A61Q19/004 , A61K8/492 , A61K8/498 , A61K31/12 , A61K31/352 , A61K31/353 , A61K31/404 , A61K31/4745 , A61K2800/92 , A61Q17/04 , A61Q19/00
摘要： Compositions and a method of protecting skin from either UV-induced immunosuppression or from UV-induced skin damage using a composition containing an extract of soy or clover, and/or the isoflavone compounds genistein, biochanin, dihydro-diadzein, formonentin, dihydro-geneistein, 2-dehydro-O-desmethyl-angolensin, tetrahydro-daidzein, equol, dehydro-equol, O-desmethyl-angolensin, or 6-hydroxy-O-desmethyl-angolensin.
摘要翻译：组合物和使用含有大豆或三叶草提取物和/或异黄酮化合物染料木黄酮，鹰嘴豆素，二氢 - 二酮糖，福音酮，二氢基质丝氨酸的组合物来保护皮肤免受UV诱导的免疫抑制或UV诱导的皮肤损伤的方法，2-脱氢-O-去甲基 - 血管紧张素，四氢 - 黄豆苷元，雌马酚，脱氢 - 牛尿酚，O-去甲基 - 血管紧张素或6-羟基-O-去甲基 - 血管紧张素。

7. 发明申请

US20110305782A1 METHODS OF CHOLESTEROL REDUCTION USING ISOFLAVONES 审中-公开
标题翻译：使用ISOFLAVONES减少胆固醇的方法
公开(公告)号：US20110305782A1
公开(公告)日：2011-12-15
申请号：US13163012
申请日：2011-06-17
申请人： Graham Edmund Kelly
发明人： Graham Edmund Kelly
IPC分类号： A61K36/48 , A61P7/00 , A61K31/352
CPC分类号： A61K31/35 , A23L11/05 , A23L11/07 , A23L33/11 , A61K31/353 , A61K31/7048 , A61K36/185 , A61K36/48 , A61K38/08 , A61K2300/00
摘要： This invention relates to natural products containing phyto-oestrogens, or phyto-oestrogen analogues, which have various beneficial physiological effects in man, and which have a variety of uses, such as to promote good health and as a dietary additive, for example. The invention describes a method of improving the health of a human by administering to the human a health supplementing amount of a phyto-oestrogen selected from genistein, daidzein formononentin and/or biochanin A. A health supplement comprising a health supplementary amount of a phyto-oestrogen selected from genisten daidzein formononentin and/or biochanin A, is also described. Preferably, the supplement also comprises at least one dietary suitable excipient, diluent, carrier or food, and may be in the form of a tablet or capsule, for example. Ideally, the phyto-oestrogen is extracted from red clover or from soya, although any source rich in isoflavones may also be used. The supplement can be used to prevent or ameliorate such conditions as breast cancer, benign breast disease, pre-menstrual syndrome, or symptoms associated with menopause in women, or various types of cancer, and especially for high blood cholesterol levels in all humans, for instance.
摘要翻译：本发明涉及含有植物雌激素或植物雌激素类似物的天然产物，其在人体中具有各种有益的生理作用，并且具有多种用途，例如促进良好的健康和作为饮食添加剂。本发明描述了一种通过向人类施用健康补充量的选自染料木黄酮，黄豆苷元和/或鹰嘴豆素A的植物雌激素来改善人体健康的方法。一种健康补充剂，其包含健康补充量的植物 - 还描述了选自染料木黄酮大豆黄酮和/或鹰嘴豆素A的雌激素。优选地，补充剂还包含至少一种膳食适合的赋形剂，稀释剂，载体或食物，并且可以是例如片剂或胶囊的形式。理想地，植物雌激素是从红三叶草或大豆提取的，尽管也可以使用富含异黄酮的任何来源。该补充剂可用于预防或改善诸如乳腺癌，良性乳腺疾病，月经前综合征或与妇女更年期相关的症状或各种类型的癌症，特别是所有人类的高血胆固醇水平的病症，实例。

8. 发明授权

US07906554B2 Combination chemotherapy compositions and methods 失效
标题翻译：组合化疗组合物和方法
公开(公告)号：US07906554B2
公开(公告)日：2011-03-15
申请号：US10530176
申请日：2003-10-02
申请人： Graham Edmund Kelly
发明人： Graham Edmund Kelly
IPC分类号： A61K33/24 , A61K31/55 , A61K31/35 , A61K31/28 , A01N43/54 , A01N43/02 , A01N55/02
CPC分类号： C07F15/0093 , A61K31/12 , A61K31/282 , A61K31/337 , A61K31/352 , A61K31/353 , A61K31/555 , A61K33/24 , A61K45/06 , A61K2300/00
摘要： This invention relates to combination therapies involving anticancer chemotherapeutic agents and isoflavones or analogues thereof. The invention further relates to compounds, methods and therapeutic uses involving, containing, comprising, including and/or for preparing platinum-isoflavonoid complexes suitable for use in the combination therapies of the invention.
摘要翻译：本发明涉及涉及抗癌化学治疗剂和异黄酮或其类似物的组合疗法。本发明还涉及涉及适用于本发明联合治疗的铂 - 异黄酮类复合物的化合物，方法和治疗用途，所述化合物，方法和治疗用途涉及，含有，包含，包含和/或制备铂 - 异黄酮型复合物。

9. 发明授权

US07622575B2 Therapeutic uses of glucan 失效
标题翻译：葡聚糖的治疗用途
公开(公告)号：US07622575B2
公开(公告)日：2009-11-24
申请号：US11499534
申请日：2006-08-04
申请人： Graham Edmund Kelly
发明人： Graham Edmund Kelly
IPC分类号： A61K31/715
CPC分类号： A61Q17/04 , A61K8/73 , A61K31/716 , A61L26/0023 , A61Q19/004 , A61Q19/08 , C08B37/0024 , C12P19/04 , Y10S514/925 , Y10S514/928 , C08L5/00
摘要： The present invention is directed to methods of using glucan compositions, comprising water insoluble microparticulate glucans, in the treatment of connective tissue injuries. The water insoluble microparticulate glucans used in the compositions comprise branched β-(1,3)(1,6) glucan. The glucan compositions used in the present invention are essentially free of unbranched β-(1,3)(1,6) glucan and non-glucan components.
摘要翻译：本发明涉及使用包含水不溶性微粒葡聚糖的葡聚糖组合物在治疗结缔组织损伤中的方法。组合物中使用的水不溶性微粒葡聚糖包含支链β-（1,3）（1,6）葡聚糖。用于本发明的葡聚糖组合物基本上不含无支化的β-（1,3）（1,6）葡聚糖和非葡聚糖组分。

10. 再颁专利

USRE40792E1 Health supplements containing phyto-oestrogens, analogues or metabolites thereof 失效
标题翻译：含有植物雌激素，类似物或代谢物的健康补品
公开(公告)号：USRE40792E1
公开(公告)日：2009-06-23
申请号：US09602191
申请日：1993-05-19
申请人： Graham Edmund Kelly
发明人： Graham Edmund Kelly
IPC分类号： A61K31/56 , A01N43/04 , A61K31/70
CPC分类号： A61K31/35 , A23L11/05 , A23L11/07 , A23L33/11 , A61K31/353 , A61K31/7048 , A61K36/185 , A61K36/48 , A61K38/08 , A61K2300/00
摘要： Compositions enriched with natural phyto-oestrogens or analogues thereof selected from Genistein, Daidzein, Formononetin and Biochanin A. These may be used as food additives, tablets or capsules for promoting health in cases of cancer, pre-menstrual syndrome, menopause or hypercholesterolaemia.
摘要翻译：丰富了天然植物雌激素或其类似物的组合物，其选自染料木黄酮，大豆黄素，角叉菜素和鹰嘴豆素A.这些可以用作食物添加剂，片剂或胶囊，用于在癌症，月经前期，绝经期或高胆固醇血症的病例中促进健康。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式