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1. 发明申请

US20090161067A1 Ophthalmic Instrument Alignment Apparatus and Method of Using Same 有权
标题翻译：眼科仪器对位装置及其使用方法
公开(公告)号：US20090161067A1
公开(公告)日：2009-06-25
申请号：US12334896
申请日：2008-12-15
申请人： Gerhard Youssefi , Rupert Veith
发明人： Gerhard Youssefi , Rupert Veith
IPC分类号： A61B3/10
CPC分类号： A61B3/152 , A61F9/008 , A61F2009/00872
摘要： An ophthalmic instrument for use with a subject's eye, comprising an interferometer having a test arm in which the subject's eye is to be positioned and a reference arm, the reference arm including a mirror adapted to be positioned such that the reference arm has a predetermined length, and an ophthalmic apparatus coupled to the interferometer such that, by altering a test arm length, a length between the ophthalmic apparatus and the eye is also altered. The mirror is positioned to achieve the predetermined length and a length of the test arm is adjusted such that interference between the light reflected from the eye and the light reflected from the mirror is achieved, the ophthalmic apparatus is optically aligned with the eye.
摘要翻译：一种用于受试者的眼睛的眼科仪器，包括具有被测者的眼睛要被定位的测试臂的干涉仪和参考臂，所述参考臂包括适于被定位成使得所述参考臂具有预定长度的反射镜以及耦合到所述干涉仪的眼科装置，使得通过改变测试臂长度，眼科装置和眼睛之间的长度也被改变。反射镜被定位成达到预定长度，并且调整测试臂的长度，使得实现从眼睛反射的光和从反射镜反射的光之间的干涉，眼科装置与眼睛光学对准。

2. 发明授权

US09186059B2 Ophthalmic instrument alignment apparatus and method of using same 有权
标题翻译：眼科仪器对准装置及其使用方法
公开(公告)号：US09186059B2
公开(公告)日：2015-11-17
申请号：US12334896
申请日：2008-12-15
申请人： Gerhard Youssefi , Rupert Veith
发明人： Gerhard Youssefi , Rupert Veith
IPC分类号： A61B3/15 , A61F9/008
CPC分类号： A61B3/152 , A61F9/008 , A61F2009/00872
摘要： An ophthalmic instrument for use with a subject's eye, comprising an interferometer having a test arm in which the subject's eye is to be positioned and a reference arm, the reference arm including a mirror adapted to be positioned such that the reference arm has a predetermined length, and an ophthalmic apparatus coupled to the interferometer such that, by altering a test arm length, a length between the ophthalmic apparatus and the eye is also altered. The mirror is positioned to achieve the predetermined length and a length of the test arm is adjusted such that interference between the light reflected from the eye and the light reflected from the mirror is achieved, the ophthalmic apparatus is optically aligned with the eye.
摘要翻译：一种用于受试者的眼睛的眼科仪器，包括具有被测者的眼睛要被定位的测试臂的干涉仪和参考臂，所述参考臂包括适于被定位成使得所述参考臂具有预定长度的反射镜以及耦合到所述干涉仪的眼科装置，使得通过改变测试臂长度，眼科装置和眼睛之间的长度也被改变。反射镜被定位成达到预定长度，并且调整测试臂的长度，使得实现从眼睛反射的光和从反射镜反射的光之间的干涉，眼科装置与眼睛光学对准。

3. 发明申请

US20070161972A1 Method, system and algorithm related to treatment planning for vision correction 审中-公开
标题翻译：与视力矫正治疗计划相关的方法，系统和算法
公开(公告)号：US20070161972A1
公开(公告)日：2007-07-12
申请号：US10550438
申请日：2004-04-12
申请人： Craig Felberg , Robin Hughes , Rupert Veith , Michael Johnson , Florian Dambacher , Arne Matthaus , Gerhard Youssefi , Friedrich Moritz
发明人： Craig Felberg , Robin Hughes , Rupert Veith , Michael Johnson , Florian Dambacher , Arne Matthaus , Gerhard Youssefi , Friedrich Moritz
IPC分类号： A61B18/18 , A61B3/00
CPC分类号： A61F9/00806 , A61B3/103 , A61B3/107 , A61F2009/00846 , A61F2009/00857 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , G06F19/3481
摘要： The invention is directed to a system and methods for automatically determining a multiple number of viable treatment plans for correcting a patient's vision via photoablative refractive surgery. Embodiments of the invention rely on selected various diagnostic input about the patient's eye to classify the eye as being particularly suitable for treatment by several different treatment algorithms. The invention is further directed to the simultaneous presentation of various treatment plans based upon selected input data and available treatment algorithms that can be reviewed, modified, and ultimately selected for application. A system embodiment according to the invention includes a component for receiving the diagnostic input data about the patient's vision, for analyzing the input data and determining the potentially usable treatment algorithms, and for processing the potentially usable treatment algorithms based upon the input data, and a component for displaying the multilevel graphical user interface which facilitates review, modification, and selection of viable treatment plans for correcting the patient's vision. The system is further operably associated with a storage medium for storing calculated and selected treatment plans which include executable instructions for a photoablative laser component of the system to deliver a selected treatment plan to the patient's eye.
摘要翻译：本发明涉及一种系统和方法，用于通过光烧伤性屈光手术来自动确定用于校正患者视力的多个可行治疗计划。本发明的实施例依赖于关于患者眼睛的所选择的各种诊断输入来将眼睛分类为特别适合于通过若干不同的治疗算法进行治疗。本发明进一步涉及基于所选择的输入数据和可被审查，修改和最终选择用于应用的可用治疗算法来同时呈现各种治疗计划。根据本发明的系统实施例包括用于接收关于患者视力的诊断输入数据的组件，用于分析输入数据并确定潜在可用的治疗算法，以及基于输入数据处理潜在可用的治疗算法，以及用于显示多级图形用户界面的组件，其便于查看，修改和选择用于校正患者视力的可行治疗计划。该系统进一步可操作地与用于存储计算和选择的治疗计划的存储介质相关联，所述治疗计划包括用于系统的光消融激光组件的可执行指令，以将选定的治疗计划传递给患者的眼睛。

4. 发明申请

US20110276043A1 Apparatus and method for providing a laser shot file 有权
标题翻译：用于提供激光拍摄文件的装置和方法
公开(公告)号：US20110276043A1
公开(公告)日：2011-11-10
申请号：US13098267
申请日：2011-04-29
申请人： Gerhard Youssefi , Ernst Hegels
发明人： Gerhard Youssefi , Ernst Hegels
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00806 , A61F2009/00848 , A61F2009/00857 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： The invention relates to an apparatus, an algorithm and a method for providing a laser shot file for use in a laser. The laser may be an excimer laser. The shot file may be applied for performing a refractive laser treatment of an eye or for producing a customized contact lens or an intraocular lens. According to the invention information with respect to a desired ablation profile is provided and a first series of laser shot positions is calculated based on the desired ablation profile. A simulated ablation profile is generated using said first series of laser shot positions and using information about pulse characteristics of a single laser shot. The simulated ablation profile is compared with the desired ablation profile and residual structures are determined.
摘要翻译：本发明涉及一种用于提供用于激光器的激光射击文件的装置，算法和方法。激光可以是准分子激光器。射击文件可以用于执行眼睛的折射激光治疗或用于制造定制的隐形眼镜或眼内透镜。根据本发明，提供关于期望的消融轮廓的信息，并且基于期望的消融轮廓来计算第一系列的激光拍摄位置。使用所述第一系列激光拍摄位置并使用关于单个激光射击的脉冲特性的信息来生成模拟消融轮廓。将模拟的消融轮廓与期望的消融轮廓进行比较，并确定残余结构。

5. 发明申请

US20110208172A1 Eye measurement and modeling techniques 审中-公开
标题翻译：眼睛测量和建模技术
公开(公告)号：US20110208172A1
公开(公告)日：2011-08-25
申请号：US13035174
申请日：2011-02-25
申请人： Gerhard Youssefi , Julia Hoff , Birgit Lutzenberger , Anton Hilger
发明人： Gerhard Youssefi , Julia Hoff , Birgit Lutzenberger , Anton Hilger
IPC分类号： A61F9/01
CPC分类号： A61F9/00804 , A61B3/102 , A61F9/00827 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088
摘要： A refractive surgical system, comprising a refractive treatment apparatus adapted to alter multiple localized regions of a cornea and an ophthalmic measurement device adapted to measure a corneal shape parameter at at least two locations on the cornea. A corneal modeling apparatus and method to calculate anticipated corneal shape parameters at two or more locations based on parameters of a refractive treatment, and compare shape parameters measured at two or more locations on the cornea corresponding to the two or more locations of the anticipated corneal shape parameters.
摘要翻译：一种屈光手术系统，包括适于改变角膜的多个局部区域的折射治疗装置和适于在角膜上的至少两个位置处测量角膜形状参数的眼科测量装置。一种角膜造型装置和方法，用于基于屈光治疗的参数计算两个或多个位置处的预期角膜形状参数，并且比较对应于预期角膜形状的两个或多个位置的角膜上的两个或多个位置处测量的形状参数参数。

6. 发明申请

US20110007945A1 FAST ALGORITHM FOR STREAMING WAVEFRONT 有权
标题翻译：用于流动WAVEFRONT的快速算法
公开(公告)号：US20110007945A1
公开(公告)日：2011-01-13
申请号：US12866122
申请日：2009-03-13
申请人： Gerhard Youssefi , Hans-Joachim Polland
发明人： Gerhard Youssefi , Hans-Joachim Polland
IPC分类号： G06K9/00
CPC分类号： A61B3/1015 , A61B3/112 , G06T7/246
摘要： The invention is generally directed to the field of image processing, and more particularly to a method and an apparatus for determining a wavefront of an object, in particular a human eye. The invention discloses a method and an apparatus for real-time wavefront sensing of an optical system utilizing two different algorithms for detecting centroids of a centroid image as provided by a Hartmann-Shack wavefront sensor. A first algorithm detects an initial position of all centroids and a second algorithm detects incremental changes of all centroids detected by said first algorithm.
摘要翻译：本发明一般涉及图像处理领域，更具体地涉及一种用于确定物体，特别是人眼的波前的方法和装置。本发明公开了一种利用两种不同的算法来检测由Hartmann-Shack波前传感器提供的质心图像的质心的光学系统的实时波前感测的方法和装置。第一算法检测所有质心的初始位置，第二算法检测由所述第一算法检测到的所有质心的增量变化。

7. 发明授权

US06926710B2 Method and system for improving vision 有权
公开(公告)号：US06926710B2
公开(公告)日：2005-08-09
申请号：US10045694
申请日：2001-10-19
申请人： Ian G. Cox , Timothy N. Turner , Gerhard Youssefi
发明人： Ian G. Cox , Timothy N. Turner , Gerhard Youssefi
IPC分类号： A61F9/01 , A61F9/013 , A61B18/18
CPC分类号： A61F9/008 , A61F9/00806 , A61F9/013 , A61F2009/00846 , A61F2009/00857 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： Methods and apparatus for improving vision incorporate the effects of biodynamical and biomechanical (biological) responses of the eye. The eye produces a biological response to trauma, such as a LASIK keratectomy or other necessary traumatic procedure in preparation for refractive surgery. By observing the biological response, a prospective treatment to correct higher order aberrations is adjusted to compensate for the biological effects. An improved photorefractive surgery system incorporates one or more suitable diagnostic devices that provide biological response information in such a manner that the patient need not change position from that assumed for the surgical procedure.

8. 发明授权

US06814729B2 Laser vision correction apparatus and control method 有权
标题翻译：激光视力矫正装置及控制方法
公开(公告)号：US06814729B2
公开(公告)日：2004-11-09
申请号：US10184441
申请日：2002-06-27
申请人： Gerhard Youssefi , Kristian Hohla , Stefan Lang
发明人： Gerhard Youssefi , Kristian Hohla , Stefan Lang
IPC分类号： A61B9007
CPC分类号： A61F9/008 , A61F9/00806 , A61F9/00808 , A61F9/00817 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882
摘要： A device readable medium for use in controlling a laser vision correction system includes a storage structure having stored therein a pre-programmed first, readable, corrective instruction reference that corresponds to an encoded customized corrective instruction determined by a calculation module external to the medium. The encoded customized corrective instruction is executable by a laser vision correction laser platform for correction of a refractive defect when the corrective instruction reference is properly recognized. A laser vision correction system including the device readable medium is described. A remunerative model relating to the device readable medium is disclosed.

9. 发明授权

US06808266B2 Objective manifest refraction 有权
$Objective manifest refraction$
标题翻译：客观明显折射
公开(公告)号：US06808266B2
公开(公告)日：2004-10-26
申请号：US10100782
申请日：2002-03-18
申请人： Gerhard Youssefi
发明人： Gerhard Youssefi
IPC分类号： A61B300
CPC分类号： A61B3/0025 , G06F19/00
摘要： An method for providing an objective manifest refraction of a patient's eye includes obtaining at least fourth-order Zernike wavefront aberration information, fitting a second-order only polynomial to the at least fourth-order data, and using this information to predict the patient's manifest refraction with an accuracy approaching the patient's subjective manifest refraction. A method is also described for prescribing an accurate vision correction based upon the objective manifest refraction. A display according to the invention includes higher-order wavefront aberrations, lower order wavefront aberrations, numerical indicia of predicted manifest refraction, and images of qualitative assessments of a patient's vision quality. A device for obtaining an objective manifest refraction is described.
摘要翻译：用于提供患者眼睛的客观清晰度折射的方法包括获得至少四阶Zernike波前像差信息，将二阶唯一多项式拟合到至少四阶数据，并且使用该信息来预测患者的明显折射准确地接近患者的主观显示折射。还描述了一种基于客观清晰度折射来规定准确的视力矫正的方法。根据本发明的显示器包括更高阶波前像差，较低阶波阵面像差，预测明显折射的数字标记以及患者视力质量的定性评估图像。描述了用于获得客观清晰度折射的装置。

10. 发明授权

US09592157B2 System and method for femto-fragmentation of a crystalline lens 有权
标题翻译：用于晶状体的毫微微碎裂的系统和方法
公开(公告)号：US09592157B2
公开(公告)日：2017-03-14
申请号：US13795641
申请日：2013-03-12
申请人： Toh Seng Goh , Brian D. McCary , David Haydn Mordaunt , Frieder Loesel , Jochen Kandulla , Gerhard Youssefi , Werner Banghard
发明人： Toh Seng Goh , Brian D. McCary , David Haydn Mordaunt , Frieder Loesel , Jochen Kandulla , Gerhard Youssefi , Werner Banghard
IPC分类号： A61B18/18 , A61F9/008
CPC分类号： A61F9/008 , A61B2218/007 , A61F9/00804 , A61F9/00812 , A61F9/00821 , A61F9/00825 , A61F2009/0087 , A61F2009/00872 , A61F2009/00878 , A61F2009/00887 , A61F2009/00897
摘要： A system and method for performing a femto-fragmentation procedure on tissue in the crystalline lens of an eye requires that a laser beam be directed and focused to a focal point in the crystalline lens of the eye. The focal point is then guided, relative to an axis defined by the eye, to create a segment cluster by causing Laser Induced Optical Breakdown (LIOB) of tissue in the crystalline lens. The resultant segment cluster includes a plurality of contiguous, elongated segments in the crystalline lens that are individually tapered from an anterior end-area to a posterior end-area. Specifically, this is done to facilitate the removal of individual segments from the segment cluster in the crystalline lens.
摘要翻译：用于对眼睛的晶状体中的组织执行毫微微碎裂过程的系统和方法要求激光束被引导并聚焦到眼晶状体中的焦点。然后相对于由眼睛定义的轴引导焦点，以通过引起晶状体中的组织的激光诱导光学细分（LIOB）来创建片段簇。所得到的片段簇包括晶状体中的多个相邻细长的片段，其从前端部区域到后端区域分别逐渐变细。具体地说，这是为了便于从晶状体中的片段簇中去除各个片段。

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