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1. 发明授权

US08241575B2 Molecularly imprinted polymer sensor device 有权
标题翻译：分子印迹聚合物传感器装置
公开(公告)号：US08241575B2
公开(公告)日：2012-08-14
申请号：US12360372
申请日：2009-01-27
申请人： George M. Murray , Andrew F. Mason , Edward W. Ott, Jr.
发明人： George M. Murray , Andrew F. Mason , Edward W. Ott, Jr.
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48
CPC分类号： G01N21/78 , G01N33/543 , G01N2600/00 , Y10T436/11 , Y10T436/142222 , Y10T436/147777 , Y10T436/201666 , Y10T436/21
摘要： A molecularly imprinted polymer sensor device for detecting the presence of a taggant molecular structure in a fluid is disclosed. The molecularly imprinted polymer sensor device comprises a molecularly imprinted crosslinked polymer having a crosslinked core and a plurality of polymer arms attached to the core, wherein the core has molecular sized cavities adapted to selectively receive and bind displacement molecules having the taggant molecular structure and a colorimetric indicator, said displacement molecule being selectively removed from the molecularly imprinted crosslinked polymer and replaced with the taggant molecular structure upon exposure to the fluid containing the taggant molecular structure therein, thereby indicating the presence of the taggant molecular structure in the fluid.
摘要翻译：公开了一种分子印迹聚合物传感器装置，用于检测流体中标签分子结构的存在。分子印迹聚合物传感器装置包括分子印迹的交联聚合物，其具有交联的芯和连接到芯的多个聚合物臂，其中芯具有分子尺寸的空腔，其适于选择性地接收和结合具有标记分子结构的置换分子和比色指示剂，所述置换分子从分子印迹的交联聚合物中选择性地除去，并且在暴露于含有其中的标记分子结构的流体时被标记分子结构置换，从而表明流体中存在标记分子结构。

2. 发明申请

US20120288944A1 Molecularly Imprinted Polymer Sensing Method 审中-公开
标题翻译：分子印迹聚合物检测方法
公开(公告)号：US20120288944A1
公开(公告)日：2012-11-15
申请号：US13554178
申请日：2012-07-20
申请人： George M. Murray , Andrew F. Mason , Edward W. Ott, JR.
发明人： George M. Murray , Andrew F. Mason , Edward W. Ott, JR.
IPC分类号： G01N21/78
CPC分类号： G01N21/78 , G01N33/543 , G01N2600/00 , Y10T436/11 , Y10T436/142222 , Y10T436/147777 , Y10T436/201666 , Y10T436/21
摘要： A method for detecting a taggant molecular structure in a fluid includes providing a molecularly imprinted polymer sensor device, contacting a molecularly imprinted crosslinked star polymer with the fluid, and correlating a color change in the fluid with the amount of the taggant molecular structure in the fluid. The device has polymer arms attached to a core, and the core has molecular sized cavities adapted to selectively receive and bind displacement molecules having the taggant molecular structure and a colorimetric indicator. The displacement molecule is selectively removed from the molecularly imprinted crosslinked polymer upon exposure to the taggant molecular structure in the fluid thereby indicating the presence of the taggant molecular structure in the fluid based on a loss of color along a length of a housing.
摘要翻译：用于检测流体中标签分子结构的方法包括提供分子印迹的聚合物传感器装置，使分子印迹的交联星形聚合物与流体接触，并将流体中的颜色变化与流体中标签分子结构的量相关联。该装置具有连接到芯的聚合物臂，并且芯具有分子尺寸的空腔，其适于选择性地接收和结合具有标记分子结构的置换分子和比色指示剂。当暴露于流体中的标记分子结构时，位移分子被选择性地从分子印迹的交联聚合物中除去，从而基于沿着壳体的长度的颜色的损失表明在流体中存在标记分子结构。

3. 发明申请

US20090197297A1 Molecularly Imprinted Polymer Sensor Device 有权
标题翻译：分子印迹聚合物传感器装置
公开(公告)号：US20090197297A1
公开(公告)日：2009-08-06
申请号：US12360372
申请日：2009-01-27
申请人： George M. Murray , Andrew F. Mason , Edward W. Ott, JR.
发明人： George M. Murray , Andrew F. Mason , Edward W. Ott, JR.
IPC分类号： C12Q1/02 , G01N21/00 , C12M1/00 , G01N21/77 , G01N33/48 , G01N33/02
CPC分类号： G01N21/78 , G01N33/543 , G01N2600/00 , Y10T436/11 , Y10T436/142222 , Y10T436/147777 , Y10T436/201666 , Y10T436/21
摘要： A molecularly imprinted polymer sensor device for detecting the presence of a taggant molecular structure in a fluid is disclosed. The molecularly imprinted polymer sensor device comprises a molecularly imprinted crosslinked polymer having a crosslinked core and a plurality of polymer arms attached to the core, wherein the core has molecular sized cavities adapted to selectively receive and bind displacement molecules having the taggant molecular structure and a colorimetric indicator, said displacement molecule being selectively removed from the molecularly imprinted crosslinked polymer and replaced with the taggant molecular structure upon exposure to the fluid containing the taggant molecular structure therein, thereby indicating the presence of the taggant molecular structure in the fluid.
摘要翻译：公开了一种分子印迹聚合物传感器装置，用于检测流体中标签分子结构的存在。分子印迹聚合物传感器装置包括分子印迹的交联聚合物，其具有交联的芯和连接到芯的多个聚合物臂，其中芯具有分子尺寸的空腔，其适于选择性地接收和结合具有标记分子结构的置换分子和比色指示剂，所述置换分子从分子印迹的交联聚合物中选择性地除去，并且在暴露于含有其中的标记分子结构的流体时被标记分子结构置换，从而表明流体中存在标记分子结构。

4. 发明授权

US07126148B2 Neutron detection based on boron activated liquid scintillation 有权
标题翻译：基于硼激活液体闪烁的中子检测
公开(公告)号：US07126148B2
公开(公告)日：2006-10-24
申请号：US10621595
申请日：2003-07-17
申请人： George M. Murray , Harvey W. Ko , Glen Southard
发明人： George M. Murray , Harvey W. Ko , Glen Southard
IPC分类号： G01V5/10
CPC分类号： G01T3/06 , Y10S250/90
摘要： A system for detecting neutron radiation. A liquid cocktail mixture comprised of a neutron absorber and a scintillator is housed in a Teflon® tube having a mirror at one end of the tube and a windowed portal at the other end of the tube. Neutrons that penetrate the tube react with the neutron absorber producing ionization that excites a scintillator to produce photons. A photo-multiplier tube is coupled with the windowed portal for receiving photons and converting the photons to electrical signals. A processing device is coupled to the photo-multiplier output for receiving and analyzing the electrical signals so as to provide a measurement pertaining to the presence and relative strength of neutron radiation. The tube can be adapted to function as a portable survey instrument. Alternatively, the tube can be stretched to cover large apertured areas. In such implementations a wavelength shifter is employed to convert light emitted to another wavelength giving a multiplier effect necessary for long light guides.
摘要翻译：一种用于检测中子辐射的系统。由中子吸收剂和闪烁体组成的液体混合物混合物容纳在管的一端具有反射镜的Teflon管和管的另一端的窗口入口。渗透管的中子与中子吸收剂反应产生电离，激发闪烁体产生光子。光电倍增管与窗口门户耦合以接收光子并将光子转换成电信号。处理装置耦合到光电倍增器输出端，用于接收和分析电信号，以提供与中子辐射的存在和相对强度有关的测量。该管可适用于便携式测量仪器。或者，管可以被拉伸以覆盖大的有孔区域。在这种实现中，使用波长移位器将发射的光转换成另一波长，给出长光导所需的乘法器效应。

5. 发明授权

US06924147B2 Method of making a polymeric food spoilage sensor 失效
标题翻译：制造聚合食品腐败传感器的方法
公开(公告)号：US06924147B2
公开(公告)日：2005-08-02
申请号：US10620245
申请日：2003-07-15
申请人： Craig A. Kelly , George M. Murray , O. Manuel Uy
发明人： Craig A. Kelly , George M. Murray , O. Manuel Uy
IPC分类号： G01N21/77 , G01N29/02 , G01N31/22 , G01N33/00 , G01N33/02
CPC分类号： G01N31/22 , G01N21/7703 , G01N29/022 , G01N33/0047 , G01N33/02 , G01N2021/772 , G01N2021/7783 , G01N2021/7786 , G01N2291/011 , G01N2291/012 , G01N2291/015 , G01N2291/02408 , G01N2291/0251 , G01N2291/0255 , G01N2291/0256 , G01N2291/0423 , G01N2291/0426 , Y10T436/173845
摘要： A polymeric food spoilage sensor comprises a polymer containing a polyazamacrocyclic transition metal complex. The complex selectively binds biogenic amines, such as cadaverine, putrescine and histamine, which are released by food spoilage microorganisms. The polymer undergoes a detectable color change upon exposure to biogenic amine, thus indicating that food spoilage has probably occurred. In one embodiment, the polymer is molecularly imprinted with the biogenic amine to impart selective binding affinity. The polymer is easily incorporated in common food containers and can be employed in fiber optic detection devices.
摘要翻译：聚合物食品腐败传感器包括含有多氮杂环过渡金属络合物的聚合物。复合物选择性地结合由食物腐败微生物释放的生物胺，如尸胺，腐胺和组胺。聚合物在暴露于生物胺时会发生可检测的颜色变化，从而表明可能发生食物腐败。在一个实施方案中，聚合物用生物胺分子印迹以赋予选择性结合亲和力。聚合物容易地结合在通常的食品容器中，并且可以用于光纤检测装置中。

6. 发明授权

US06852891B2 Method of inhibiting methaphetamine synthesis 失效
标题翻译：抑制甲基苯丙胺合成的方法
公开(公告)号：US06852891B2
公开(公告)日：2005-02-08
申请号：US10297626
申请日：2001-06-21
申请人： George M. Murray , Craig A. Kelly , O. Manuel Uy , Lawrence W. Hunter , David S. Lawrence
发明人： George M. Murray , Craig A. Kelly , O. Manuel Uy , Lawrence W. Hunter , David S. Lawrence
IPC分类号： C07C209/68 , C07D239/94 , C07D401/12 , C07D403/12 , C07D409/12 , C07D417/12
CPC分类号： C07C209/68
摘要： A method of inhibiting or preventing the use of anhydrous ammonia as a solvent in a dissolving metal reduction process comprises adding to anhydrous ammonia a chemical reagent which is capable of scavenging solvated electrons generated when alkali or alkaline earth metal is dissolved in the anhydrous ammonia, the chemical reagent being added to the anhydrous ammonia such that when alkali metal is dissolved in the anhydrous ammonia containing the chemical reagent and thereafter ephedrine, pseudoephedrine or combination thereof is introduced to the anhydrous ammonia to produce a reaction product, the methamphetamine yield in the reaction product is below 50%, preferably below 10%, and more preferably below 1%. Preferred chemical reagents include Fe(III)citrate, ferrocene, 2-chloro-6-(trichloromethyl)pyridine and 1,1,1,2-tetrafluoroethane.
摘要翻译：在溶解金属还原方法中抑制或防止使用无水氨作为溶剂的方法包括向无水氨中加入能够清除当碱金属或碱土金属溶解在无水氨中时产生的溶剂化电子的化学试剂，将化学试剂加入到无水氨中，使得当将碱金属溶解在含有化学试剂的无水氨中，然后将麻黄碱，伪麻黄碱或其组合引入无水氨以产生反应产物时，反应产物中的甲基苯丙胺产率低于50％，优选低于10％，更优选低于1％。优选的化学试剂包括柠檬酸铁（III），二茂铁，2-氯-6-（三氯甲基）吡啶和1,1,1,2-四氟乙烷。

7. 发明申请

US20110049390A1 Method and Apparatus for Detection of Bioaerosols 审中-公开
标题翻译：用于检测生物溶胶的方法和装置
公开(公告)号：US20110049390A1
公开(公告)日：2011-03-03
申请号：US12939265
申请日：2010-11-04
申请人： George M. Murray , Cheryl S. Schein , David R. Kohler , Jennifer L. Sample , Jennifer A. Nix , Protagoras N. Cutchis , Adam K. Arabian , Harvey W. Ko , Micah A. Carlson , Michael P. McLoughlin
发明人： George M. Murray , Cheryl S. Schein , David R. Kohler , Jennifer L. Sample , Jennifer A. Nix , Protagoras N. Cutchis , Adam K. Arabian , Harvey W. Ko , Micah A. Carlson , Michael P. McLoughlin
IPC分类号： G01N21/64 , G01J1/58
CPC分类号： G01N21/645 , G01N21/64 , G01N21/6408 , G01N21/6486 , G01N2021/6413 , G01N2021/6421
摘要： A method and apparatus for evaluating a bioaerosol sample is provided which includes detecting frequency and/or time resolution factors that allow discriminate between a plurality of signals emitted by the bioaerosol to selectively detect biological materials contained in the bioaerosol sample from materials of non-biological origin and potentially associated with a pathogenic bioaerosol.
摘要翻译：提供了一种用于评估生物气溶胶样品的方法和装置，其包括检测频率和/或时间分辨率因子，其允许区分由生物气溶胶发射的多个信号，以从非生物来源的材料中选择性地检测生物气溶胶样品中包含的生物材料并且可能与致病性生物气溶胶相关。

8. 发明授权

US07494769B2 Method and apparatus for detection of bioaerosols 有权
标题翻译：用于检测生物溶胶的方法和装置
公开(公告)号：US07494769B2
公开(公告)日：2009-02-24
申请号：US10503168
申请日：2003-04-16
申请人： George M. Murray , Cheryl S. Schein , David R. Kohler , Jennifer L. Sample , Jennifer A. Nix , Protagoras N. Cutchis , Adam K. Arabian , Harvey W. Ko , Micah A. Carlson , Michael P. McLoughlin
发明人： George M. Murray , Cheryl S. Schein , David R. Kohler , Jennifer L. Sample , Jennifer A. Nix , Protagoras N. Cutchis , Adam K. Arabian , Harvey W. Ko , Micah A. Carlson , Michael P. McLoughlin
IPC分类号： C12Q1/70
CPC分类号： G01N21/645 , G01N21/64 , G01N21/6408 , G01N21/6486 , G01N2021/6413 , G01N2021/6421
摘要： A method and apparatus for evaluating a bioaerosol sample is provided which includes detecting frequency and/or time resolution factors that allow discriminate between a plurality of signals emitted by the bioaerosol to selectively detect biological materials contained in the bioaerosol sample from materials of non-biological origin and potentially associated with a pathogenic bioaerosol.
摘要翻译：提供了一种用于评估生物气溶胶样品的方法和装置，其包括检测频率和/或时间分辨率因子，其允许区分由生物气溶胶发射的多个信号，以从非生物来源的材料中选择性地检测生物气溶胶样品中包含的生物材料并且可能与致病性生物气溶胶相关。

9. 发明授权

US07279096B2 Polymer based permeable membrane for removal of ions 有权
标题翻译：用于去除离子的基于聚合物的可渗透膜
公开(公告)号：US07279096B2
公开(公告)日：2007-10-09
申请号：US10924666
申请日：2004-08-24
申请人： George M. Murray
发明人： George M. Murray
IPC分类号： B01D39/00 , B01D39/14 , C02E1/44 , B32B5/02
CPC分类号： B01D67/0006 , B01D61/00 , B01D61/002 , B01D61/005 , B01D67/003 , B01D69/02 , B01D71/28 , B01D2323/18 , B01D2323/30 , B01D2325/04 , B01D2325/14 , B01D2325/16 , B01D2325/20 , B01J20/26 , B01J20/261 , B01J20/267 , B01J20/268 , B01J20/28033 , B01J20/3057 , B01J45/00 , B01J47/12 , C02F1/285 , C02F1/44 , C02F2101/105 , C02F2101/163 , C02F2101/203 , Y10T436/25
摘要： Molecularly imprinted polymer membranes for selectively collecting phosphate, nitrate and ferric ions are disclosed, prepared by copolymerizing a matrix monomer, cross-linking agent, ion imprinting complex, permeability agent and polymerization initiator, after which the ions of the ion imprinting complex are permeability agent are removed. The permeability agent creates channels in the membrane permitting the ion binding sites in the membrane to communicate with the exterior surface of the membrane.
摘要翻译：公开了用于选择性收集磷酸盐，硝酸盐和铁离子的分子印迹聚合物膜，其通过共聚基质单体，交联剂，离子印迹络合物，渗透剂和聚合引发剂制备，其后离子印迹络合物的离子是渗透剂被删除。渗透剂在膜中产生通道，允许膜中的离子结合位点与膜的外表面连通。

10. 发明授权

US06967103B2 Apparatus and methods for detecting explosives and other substances 有权
标题翻译：用于检测爆炸物和其他物质的装置和方法
公开(公告)号：US06967103B2
公开(公告)日：2005-11-22
申请号：US10240902
申请日：2001-05-03
申请人： Paul D. Schwartz , George M. Murray , O. Manuel Uy , Binh Q. Le , David D. Scott , Ark L. Lew , Sharon X. Ling , Joseph J. Suter
发明人： Paul D. Schwartz , George M. Murray , O. Manuel Uy , Binh Q. Le , David D. Scott , Ark L. Lew , Sharon X. Ling , Joseph J. Suter
IPC分类号： G01N21/64 , G01N21/77 , G01N33/22
CPC分类号： G01N21/643 , G01N21/7703 , G01N33/0057 , G01N2021/6484 , G01N2021/7709 , G01N2021/7786 , Y10T436/17 , Y10T436/170769 , Y10T436/173076 , Y10T436/173845
摘要： An explosive detector that utilizes an array of molecularly imprinted polymer (MIP) coated, bifurcated fiber optic cables to form an image of a target molecule source. Individual sensor fiber assemblies, each with a calibrated airflow, are used to expose the fibers to the target molecule. The detector energizes a dedicated excitation light source for each fiber, while simultaneously reading and processing the intensity of the resulting fluorescence that is indicative of the concentration of the target molecule. Processing electronics precisely controls the excitation current, and measures the detected signal from each narrow band pass filter and photodiode. A computer with display processes the data to form an image of the target molecule source that can be used to identify the source even when low level contamination of the same molecule is present. The detector can be used to detect multiple and/or non-explosive targets by varying the MIP coating.
摘要翻译：一种利用分子印迹聚合物（MIP）涂覆的分叉光纤电缆阵列形成靶分子源的图像的爆炸检测器。使用具有校准气流的各个传感器纤维组件将纤维暴露于靶分子。检测器为每个纤维激发专用激发光源，同时读取和处理指示靶分子浓度的所得荧光的强度。处理电子设备精确控制激励电流，并测量来自每个窄带通滤波器和光电二极管的检测信号。具有显示器的计算机处理数据以形成目标分子源的图像，其即使存在相同分子的低水平污染物也可用于鉴定来源。检测器可用于通过改变MIP涂层来检测多个和/或非爆炸性靶标。

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