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1. 发明授权

US07902145B2 Terminal sterilization of injectable collagen products 有权
标题翻译：可注射胶原蛋白产品终端灭菌
公开(公告)号：US07902145B2
公开(公告)日：2011-03-08
申请号：US11383845
申请日：2006-05-17
申请人： George Chu , C. Randall Harrell , Hector J. Gomez
发明人： George Chu , C. Randall Harrell , Hector J. Gomez
IPC分类号： C12M1/12 , A61K38/00
CPC分类号： A61L2/007 , A61L2/0011 , A61L2/0035 , A61L2/0041 , A61L2/08 , A61L2202/23
摘要： Methods of sterilizing dermal fillers and injectable collagen material have been developed which reduce the level of active biological contaminants or pathogens without adversely affecting the material, i.e., wherein the dermal fillers and injectable collagen material retain their same properties before and after its terminal sterilization. In one embodiment the method for sterilizing the dermal filler or injectable collagen material that is sensitive to radiation contains the steps of protecting the filler or material from radiation, and irradiating the filler or material with a suitable dose of radiation for a time and at a rate effective to sterilize the filler or injectable material. In a preferred embodiment the method for sterilizing the dermal filler or injectable collagen material that is sensitive to radiation includes the steps of a) freezing the filler or material at a temperature below its freezing temperature, which is generally below 0° C. and b) irradiating the filler or material with a suitable dose of radiation at an effective rate for a time effective to sterilize the filler or material. The exposure of the radiation differs depending upon the density of the filler or material, but is preferably between 5 kGy and 12 kGy and more preferably between 6 kGy and 8 kGy. These doses result in a sterility assurance level (SAL) of 10−6 SAL for the filler or material.
摘要翻译：已经开发了对皮肤填充剂和可注射胶原材料进行灭菌的方法，其降低活性生物污染物或病原体的水平，而不会对材料产生不利影响，即其中真皮填料和可注射胶原材料在其终端灭菌前后保持相同的性质。在一个实施方案中，对对辐射敏感的真皮填料或可注射胶原材料进行灭菌的方法包括以下步骤：保护填料或材料免受辐射，并且以适当剂量的辐射照射填料或材料一段时间有效地对填料或可注射材料进行灭菌。在优选的实施方案中，对对辐射敏感的真皮填料或可注射胶原材料进行灭菌的方法包括以下步骤：a）在低于其冷冻温度的温度下将填料或材料冷冻，其一般低于0℃，和b）用合适剂量的辐射以有效速率照射填料或材料一段时间以有效地消除填料或材料。辐射的曝光取决于填料或材料的密度而不同，但优选在5kGy和12kGy之间，更优选在6kGy和8kGy之间。这些剂量导致填料或材料的10-6 SAL的无菌保证水平（SAL）。

2. 发明授权

US6149356A Portable pneumatic tool assembled with module units 有权
标题翻译：便携式气动工具组装有模块单元
公开(公告)号：US6149356A
公开(公告)日：2000-11-21
申请号：US293531
申请日：1999-04-15
申请人： George Chu , Chien-Chung Chuang
发明人： George Chu , Chien-Chung Chuang
IPC分类号： B05B7/24 , B21J15/06 , B21J15/22 , B25B21/00 , B25B27/00 , B25C5/13 , B25F5/02 , B23B51/06
CPC分类号： B25F5/02 , B05B7/2405 , B21J15/105 , B21J15/22 , B25B21/00 , B25B27/0014 , B25C5/13 , Y10T408/44 , Y10T408/65
摘要： A portable pneumatic tool includes a housing composed of two symmetric half shells or several partially cut-away shells; an air inlet module unit, a valve actuating module unit and an operating (or functioning) module unit fluidically communicated with one another and connected with flexible hoses among the module units; and a shock-absorbing unit retained between the operating module unit and the housing; whereby upon embedding or fixation of all the module units into the corresponding cavities in the shells and upon combination of the shells, a portable pneumatic tool will be instantly obtained having advantages of light weight, shock-absorbable property, easy assembly, lower production cost and convenient maintenance.
摘要翻译：便携式气动工具包括由两个对称的半壳或几个部分切除的壳组成的壳体; 空气入口模块单元，阀致动模块单元和操作（或功能）模块单元，其在所述模块单元之间彼此流动连通并与软管连接; 以及保持在所述操作模块单元和所述壳体之间的减震单元; 由此，当将所有模块单元嵌入或固定到壳体中的相应空腔中并且在壳体组合时，将立即获得便携式气动工具，其具有重量轻，可吸收吸收性能，易于组装，降低生产成本的优点，维修方便。

3. 发明申请

US20100192705A1 ANTI-VIBRATION TORQUE SENSING AND CONTROL DEVICE FOR TOOLS 有权
标题翻译：用于工具的抗振动扭矩感应和控制装置
公开(公告)号：US20100192705A1
公开(公告)日：2010-08-05
申请号：US12322277
申请日：2009-02-02
申请人： George Chu
发明人： George Chu
IPC分类号： G01L3/00
CPC分类号： B25B23/14
摘要： A torque sensing and control device for tools comprises: a torque sensing and transmitting adapter fabricated with rib structure and mounted on or built in a fastening tool; at least a torque sensor secured on at least a rib evenly spaced and formed on the adapter and operatively sensing a torque signal when applying a torque on a work or object when rotatably operating the fastening tool; and a digital display control module operatively receiving the torque signal, displaying a torque data and generating an audio or visual warning signal for reminding the user for stopping operation of the fastening tool, or for switching off power or air supply to the fastening tool, and or actuating a delay control to restart a next fastening operation in a pre-determined time interval.
摘要翻译：用于工具的扭矩感测和控制装置包括：扭矩感测和传递适配器，其制造成具有肋结构并且安装在或内置在紧固工具中; 至少一个扭矩传感器固定在至少一个肋上并均匀地间隔并形成在适配器上并且当可旋转地操作紧固工具时在工件或物体上施加扭矩时可操作地感测扭矩信号; 以及数字显示控制模块，可操作地接收扭矩信号，显示扭矩数据并产生用于提醒用户停止紧固工具的操作的音频或视觉警告信号，或用于切断对紧固工具的动力或空气供应，以及或启动延迟控制以在预定的时间间隔内重新开始下一个紧固操作。

4. 发明申请

US20050054771A1 Adhesive tissue repair patch 有权
标题翻译：粘膜组织修复补片
公开(公告)号：US20050054771A1
公开(公告)日：2005-03-10
申请号：US10971684
申请日：2004-10-22
申请人： Louis Sehl , Olof Trollsas , Donald Wallace , David Toman , Frank DeLustro , Jacqueline Schroeder , George Chu
发明人： Louis Sehl , Olof Trollsas , Donald Wallace , David Toman , Frank DeLustro , Jacqueline Schroeder , George Chu
IPC分类号： A61F2/00 , A61L24/04 , A61L24/08 , A61L27/26 , A61L27/34 , A61L27/54 , A61L31/04 , A61L31/16 , C08B37/00 , C08F283/00 , C08F283/04 , C08F283/06 , C08G65/329 , C08G75/04 , C08G75/26 , C08H1/00 , C08H1/06 , C08L51/00 , C08L53/00 , C08L67/06 , C08L71/02 , C08L81/02 , C09D167/02 , C09J151/00 , C09J153/00 , C09J189/06
CPC分类号： A61L24/043 , A61F2/0063 , A61L24/08 , A61L24/102 , A61L27/24 , A61L27/26 , A61L31/041 , A61L31/044 , C08B37/0075 , C08F283/00 , C08F283/04 , C08F283/06 , C08G65/329 , C08G75/045 , C08G75/26 , C08H1/00 , C08H1/06 , C08L51/003 , C08L53/00 , C08L67/06 , C08L71/02 , C08L81/02 , C09D167/02 , C09J151/003 , C09J153/00 , C09J189/06 , C08L89/06 , C08L5/16 , C08L91/06 , C08L2666/26 , C08L71/00
摘要： A method of tissue repair is provided using a biocompatible nonimmunogenic adhesive composition. The adhesive composition comprises collagen and a plurality of crosslinkable components having reactive functional groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. Kits for use in carrying out the method of the invention are also provided, as are pretreated surgically acceptable patches that have been coated with the aforementioned adhesive composition.
摘要翻译：使用生物相容性非免疫原性粘合剂组合物提供组织修复的方法。粘合剂组合物包含胶原和多个在其上具有反应性官能团的可交联组分，其中官能团被选择以使得组分之间能够进行交联，即交联。还提供了用于实施本发明的方法的试剂盒，以及已经用上述粘合剂组合物涂覆的预处理的外科手术可接受的贴剂。

5. 发明授权

US5428024A High concentration homogenized collagen compositions 失效
标题翻译：高浓度均质胶原组合物
公开(公告)号：US5428024A
公开(公告)日：1995-06-27
申请号：US229859
申请日：1994-04-19
申请人： George Chu , Brenda Trobaugh , Prema Rao
发明人： George Chu , Brenda Trobaugh , Prema Rao
IPC分类号： A61L27/00 , A61F2/00 , A61K38/17 , A61L27/24 , C08L89/00 , C08L89/06 , A61B19/00 , A61L15/00
CPC分类号： C08L89/06 , A61L27/24 , A61F2310/00365
摘要： High concentration collagen compositions having improved persistence when administered for soft tissue augmentation are prepared from both cross-linked and non-cross-linked collagen starting materials. Suspensions of the starting materials are subjected to vigorous mechanical disruption to reduce the average collagen fiber size to below a threshold level which enhances the injectability of the composition. Thus, both enhanced injectability and enhanced persistence may be achieved using the same formulations.
摘要翻译：通过交联和非交联胶原起始材料制备具有改善持续性的高浓度胶原组合物，当用于软组织增加时，起始材料的悬浮液受到剧烈的机械破坏，以将胶原纤维的平均尺寸降低到阈值以下，从而提高了组合物的注射性。因此，可以使用相同的配方来实现增强的注射性和增强的持续性。

6. 发明授权

US07743791B2 Air control module unit for portable pneumatic tool 有权
标题翻译：便携式气动工具气控模块
公开(公告)号：US07743791B2
公开(公告)日：2010-06-29
申请号：US11739724
申请日：2007-04-25
申请人： George Chu
发明人： George Chu
IPC分类号： F16K11/20
CPC分类号： F16L29/007 , F16L41/03 , Y10T137/877 , Y10T137/87893
摘要： The present invention generally relates to an air control module unit for a portable pneumatic tool, more particularly, to an air control module unit that actuates a valve stem inside an air inlet block of the air inlet module by a correspondent air bleed valve in the air actuation module. The air control module unit for a portable pneumatic tool comprising: an air inlet module, which has at least one valve stem inside an air inlet block, the air inlet block having plug screws on both ends towards the valve stem and one plug screw on the intersectional direction of the valve stem with at least one air inlet port opening for hooking up the compressed air; an air actuation module having a bleed valve inside the valve block; a plurality of flexible air hoses with a plurality of dimensions and being prepared for connecting the air inlet module and air actuation module; and a plurality of hose connectors and rubber seats with a plurality of types for connecting the air inlet module and the air operation module.
摘要翻译：本发明一般涉及用于便携式气动工具的空气控制模块单元，更具体地说，涉及一种空气控制模块单元，该空气控制模块单元通过空气中相应的排气阀致动空气入口模块内的阀杆驱动模块一种用于便携式气动工具的空气控制模块单元，包括：空气入口模块，其具有位于空气入口块内的至少一个阀杆，空气入口块具有两端朝向阀杆的塞子螺钉，阀杆的交叉方向具有至少一个用于钩住压缩空气的进气口开口; 空气致动模块，其在所述阀块内具有放气阀; 多个具有多个尺寸的柔性空气软管并被准备用于连接进气模块和空气致动模块; 以及多个软管连接器和具有多种类型的橡胶座，用于连接进气模块和空气操作模块。

7. 发明授权

US07501693B2 LDO regulator with ground connection through package bottom 有权
标题翻译： LDO调节器通过封装底部接地
公开(公告)号：US07501693B2
公开(公告)日：2009-03-10
申请号：US11561175
申请日：2006-11-17
申请人： George Chu , Martin Alter
发明人： George Chu , Martin Alter
IPC分类号： H01L23/495 , H01L23/04
CPC分类号： H01L23/49548 , H01L23/3107 , H01L23/49513 , H01L24/29 , H01L24/32 , H01L24/33 , H01L24/48 , H01L24/49 , H01L24/73 , H01L2224/04026 , H01L2224/29101 , H01L2224/2919 , H01L2224/32245 , H01L2224/48091 , H01L2224/48247 , H01L2224/48257 , H01L2224/4911 , H01L2224/73265 , H01L2924/00014 , H01L2924/01006 , H01L2924/01015 , H01L2924/01023 , H01L2924/01024 , H01L2924/01029 , H01L2924/01033 , H01L2924/01047 , H01L2924/01082 , H01L2924/014 , H01L2924/0665 , H01L2924/078 , H01L2924/0781 , H01L2924/10253 , H01L2924/1306 , H01L2924/14 , H01L2924/181 , H01L2924/18301 , H01L2924/19041 , H01L2924/19043 , H01L2924/19107 , H01L2924/00 , H01L2924/00012 , H01L2224/45099 , H01L2224/45015 , H01L2924/207
摘要： A low dropout (LDO) regulator device includes an LDO regulator integrated circuit housed in a 4-pin quad flat no-lead (QFN) package where the exposed die paddle is used as the ground terminal. The LDO regulator integrated circuit is formed on a semiconductor substrate. The 4-pin QFN package includes four perimeter lands connected to the input terminal, the output terminal, the enable terminal and the bypass terminal of the LDO regulator integrated circuit. The die paddle is to be electrically connected to a ground potential to allow the ground current of the LDO regulator integrated circuit to flow through the substrate and the die paddle of the 4-pin QFN package.
摘要翻译：低压差（LDO）调节器器件包括一个LDO稳压器集成电路，该集成电路采用4引脚四边形无引线（QFN）封装，裸露的裸片用作接地端子。 LDO稳压器集成电路形成在半导体衬底上。 4引脚QFN封装包括连接到LDO稳压器集成电路的输入端子，输出端子，使能端子和旁路端子的四个周边焊盘。芯片电路要与地电位电连接，以使LDO稳压器集成电路的接地电流流过基板和4引脚QFN封装的管芯。

8. 发明申请

US20080135994A1 LDO Regulator with Ground Connection Through Package Bottom 有权
标题翻译： LDO调节器，通过封装底部接地连接
公开(公告)号：US20080135994A1
公开(公告)日：2008-06-12
申请号：US11561175
申请日：2006-11-17
申请人： George Chu , Martin Alter
发明人： George Chu , Martin Alter
IPC分类号： H01L23/495
CPC分类号： H01L23/49548 , H01L23/3107 , H01L23/49513 , H01L24/29 , H01L24/32 , H01L24/33 , H01L24/48 , H01L24/49 , H01L24/73 , H01L2224/04026 , H01L2224/29101 , H01L2224/2919 , H01L2224/32245 , H01L2224/48091 , H01L2224/48247 , H01L2224/48257 , H01L2224/4911 , H01L2224/73265 , H01L2924/00014 , H01L2924/01006 , H01L2924/01015 , H01L2924/01023 , H01L2924/01024 , H01L2924/01029 , H01L2924/01033 , H01L2924/01047 , H01L2924/01082 , H01L2924/014 , H01L2924/0665 , H01L2924/078 , H01L2924/0781 , H01L2924/10253 , H01L2924/1306 , H01L2924/14 , H01L2924/181 , H01L2924/18301 , H01L2924/19041 , H01L2924/19043 , H01L2924/19107 , H01L2924/00 , H01L2924/00012 , H01L2224/45099 , H01L2224/45015 , H01L2924/207
摘要： A low dropout (LDO) regulator device includes an LDO regulator integrated circuit housed in a 4-pin quad flat no-lead (QFN) package where the exposed die paddle is used as the ground terminal. The LDO regulator integrated circuit is formed on a semiconductor substrate. The 4-pin QFN package includes four perimeter lands connected to the input terminal, the output terminal, the enable terminal and the bypass terminal of the LDO regulator integrated circuit. The die paddle is to be electrically connected to a ground potential to allow the ground current of the LDO regulator integrated circuit to flow through the substrate and the die paddle of the 4-pin QFN package.
摘要翻译：低压差（LDO）调节器器件包括一个LDO稳压器集成电路，该集成电路采用4引脚四边形无引线（QFN）封装，裸露的裸片用作接地端子。 LDO稳压器集成电路形成在半导体衬底上。 4引脚QFN封装包括连接到LDO稳压器集成电路的输入端子，输出端子，使能端子和旁路端子的四个周边焊盘。芯片电路要与地电位电连接，以使LDO稳压器集成电路的接地电流流过基板和4引脚QFN封装的管芯。

9. 发明申请

US20050114644A1 Deterministic system and method for implementing software distributed between a desktop and a remote device 有权
标题翻译：用于实现分布在桌面和远程设备之间的软件的确定性系统和方法
公开(公告)号：US20050114644A1
公开(公告)日：2005-05-26
申请号：US10721396
申请日：2003-11-25
申请人： George Chu , Timothy Ng.
发明人： George Chu , Timothy Ng.
IPC分类号： G06F9/445 , G06F9/46
CPC分类号： G06F9/54 , G06F9/445 , G06F2209/549
摘要： Software running on a desktop device determines whether or not binaries (executables) need to be pushed to a remote device. If binaries need to be pushed to the remote device, the desktop determines which particular binaries need to be pushed to the remote device, and pushes the needed binaries to the remote device. Once all needed binaries are loaded onto the remote device, functions on the remote device can be executed via remote procedure calls.
摘要翻译：在桌面设备上运行的软件确定是否需要将二进制文件（可执行文件）推送到远程设备。如果需要将二进制文件推送到远程设备，桌面将确定需要将哪些特定二进制文件推送到远程设备，并将所需的二进制文件推送到远程设备。一旦所有需要的二进制文件加载到远程设备上，远程设备上的功能就可以通过远程过程调用执行。

10. 发明授权

US5428022A Composition of low type III content human placental collagen 失效
标题翻译：低III型含量人胎盘胶原的组成
公开(公告)号：US5428022A
公开(公告)日：1995-06-27
申请号：US921810
申请日：1992-07-29
申请人： Howard Palefsky , Bruce B. Pharriss , George Chu
发明人： Howard Palefsky , Bruce B. Pharriss , George Chu
IPC分类号： A61K38/17 , A61F2/00 , A61L27/24 , C07K14/00 , A61B19/00 , A61F2/14 , C07K5/08
CPC分类号： A61L27/24 , A61F2310/00365
摘要： A human placental collagen composition for use in soft tissue augmentation comprising an aqueous suspension of a homogenized nonirradiation-sterilized mixture of type I and type III human placental collagen, wherein the type III collagen constitutes less than about 10% by weight of the mixture.
摘要翻译：一种用于软组织增强的人胎盘胶原组合物，其包含I型和III型人胎盘胶原的均匀化非照射灭菌混合物的水性悬浮液，其中III型胶原构成混合物的约10重量％。

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