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1. 发明授权

US06254575B1 Reaccessible medical needle safety devices and methods 有权
标题翻译：无障碍医疗针头安全装置及方法
公开(公告)号：US06254575B1
公开(公告)日：2001-07-03
申请号：US09434036
申请日：1999-11-04
申请人： Gale H. Thorne, Jr. , Mark Nelson , F. Mark Ferguson , Kendall P. Thorne , Michael L. Thorne , David L. Thorne , Gale H. Thorne , Michael A. Wilson
发明人： Gale H. Thorne, Jr. , Mark Nelson , F. Mark Ferguson , Kendall P. Thorne , Michael L. Thorne , David L. Thorne , Gale H. Thorne , Michael A. Wilson
IPC分类号： A61M532
CPC分类号： A61M5/1782 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/3275 , Y10S128/919
摘要： A retractable and extendable medical needle protective shield which provides opportunity for accessing and reaccessing a medical needle and associated sharpened needle tip and recovering the needle and tip for safety between accesses. The shield includes a needle guide which assures the needle tip is untouched by any part of the shield as the shield is displaced to cover and uncover the needle. A releasible latch is provided to guard against inadvertent removal of the protective shield between accesses. An unreleasible latch is also provided to secure the shield relative to the latch preparatory to final disposal. In combination with the protective shield, a plurality of adapters are disclosed which provide examples of passively operated, protected access to membrane pierceable fluid sources such as a “Y” connection site of an IV set line, a drug vial, a vacuum sample tube, an umbilical cord holder and a hypodermic site.
摘要翻译：可伸缩和可延伸的医用针头保护罩，提供进入和重新使用医疗针头和相关联的尖锐针尖的机会，并在接近之间安全地恢复针头和尖端。护罩包括针导向器，当护罩移位以覆盖并露出针时，针引导件确保针尖不被罩的任何部分所接触。提供可释放的闩锁以防止在通路之间无意中去除保护屏蔽。还提供了不可释放的闩锁以固定屏蔽件相对于闩锁的准备以最终处置。与保护屏蔽结合，公开了多个适配器，其提供被动操作的受保护的进入膜可刺穿流体源的实例，诸如IV设定线的“Y”连接部位，药物小瓶，真空样品管，脐带架和皮下注射部位。

2. 发明授权

US06358265B1 Single-step disposable safety lancet apparatus and methods 失效
标题翻译：单步一次性安全刺血针装置及方法
公开(公告)号：US06358265B1
公开(公告)日：2002-03-19
申请号：US09619043
申请日：2000-07-18
申请人： Gale H. Thorne, Jr. , Michael A. Wilson , Charles V. Owen , David L. Thorne , B. Chance Bagley
发明人： Gale H. Thorne, Jr. , Michael A. Wilson , Charles V. Owen , David L. Thorne , B. Chance Bagley
IPC分类号： A61B1732
CPC分类号： A61B5/15142 , A61B5/150022 , A61B5/150412 , A61B5/150503 , A61B5/150618 , A61B5/150702 , A61B5/150885 , A61B5/15111 , A61B5/15117 , A61B5/1513 , A61B5/15144
摘要： Three embodiments of a single-step lancet are disclosed. Each such lancet embodiment provides true one-step operation. In a single operational step requiring only a unidirectional displacement of an actuator into a housing, a lancet blade is removed from an aseptic environment which protects and retains the lancet blade in a pre-sterilized state within the housing prior to use, stores energy in an energy storage medium, activates the lancet blade to perform a lance and for safety retracts the lancet blade into the housing.
摘要翻译：公开了单步骤柳叶刀的三个实施例。每个这样的刺血针实施例提供真正的一步操作。在单个操作步骤中，仅需要将致动器单向位移到壳体中，柳叶刀叶片从无菌环境中移除，在使用之前保护并保持柳叶刀叶片处于壳体内的预灭菌状态，将能量存储在能量储存介质，激活柳叶刀叶片进行喷枪，并将柳叶刀刀片安全地缩回到壳体内。

3. 发明授权

US6149629A Medical needle safety apparatus and methods 有权
标题翻译：医疗针头安全装置及方法
公开(公告)号：US6149629A
公开(公告)日：2000-11-21
申请号：US312317
申请日：1999-05-14
申请人： Michael A. Wilson , Gale H. Thorne
发明人： Michael A. Wilson , Gale H. Thorne
IPC分类号： A61M5/32
CPC分类号： A61M5/3271 , A61M5/3202
摘要： An invention which provides for making low cost apparatus and one-hand activation methods for shielding a syringe needle as a safety precaution after each needle use. A shield, which may be used as a protective cover for the needle during initial transport to site of use, is linearly actuated to three distinct stops by action of a single hand, thereby leaving the second hand of a user free for patient care. The shield is releasible from two of the three stops to make possible uncovering of the needle preparatory to use and temporary needle protection between needle uses. The shield has an elongated hollow barrel shape which is sized to fit snugly about, yet slide smoothly over a body of a syringe associated with the needle. The barrel shape of the shield is longitudinally interrupted by a scissure in which an arm which is hingeably affixed to the shield resides. The arm is selectively bent to provide operative surfaces which permit the shield to be released from two of the three stops and further displaced to selected stops by inward depression of the arm. The invention utilizes a collet with a slot and a pawl which interacts with at least one set of ratchet teeth on the arm to provide one of the releasible stops. Generally release from stops is actuated by inward pressure on a predetermined portion of the arm.
摘要翻译：本发明提供了在每次使用针头之后制造低成本的装置和用于屏蔽注射器针头的单手激活方法作为安全预防措施。在初始运送到使用地点期间可用作针的保护罩的护罩通过单手的动作被线性致动到三个不同的止挡部，从而使用户的二手免于病人护理。防护罩可以从三个挡块中的两个位置脱离，以使针头可以准备使用，也可以在针头之间临时保护针头。护罩具有细长的中空筒状，其尺寸适于紧贴地配合，但平滑地滑过与针相关联的注射器的主体。屏蔽件的桶形状由其中可铰接地固定在屏蔽件上的臂的切口纵向间断。臂被选择性地弯曲以提供操作表面，其允许屏蔽件从三个挡块中的两个挡块释放，并通过臂的向内按压而进一步移位到选定的挡块。本发明利用具有槽和棘爪的夹头，其与臂上的至少一组棘轮齿相互作用以提供可释放止挡件之一。通常从止动件释放通过在臂的预定部分上的向内的压力来致动。

4. 发明授权

US07700118B2 Molecular differences between species of the M. tuberculosis complex 有权
标题翻译：结核分枝杆菌菌种之间的分子差异
公开(公告)号：US07700118B2
公开(公告)日：2010-04-20
申请号：US12049063
申请日：2008-03-14
申请人： Marcel Behr , Peter Small , Gary Schoolnik , Michael A. Wilson
发明人： Marcel Behr , Peter Small , Gary Schoolnik , Michael A. Wilson
IPC分类号： A61K39/04 , A61K39/205 , A61K39/00
CPC分类号： C12Q1/689 , C12Q2600/156
摘要： Specific genetic deletion are identified in mycobacteria isolates, including variations in the M. tuberculosis genome sequence between isolates, and numerous deletion present in BCG as compared to M. tb. These deletions are used as markers to distinguish between pathogenic and avirulent strains, and as a marker for particular M. tb isolates. Deletions specific to vaccine strains of BCG are useful in determining whether a positive tuberculin skin test is indicative of actual tuberculosis infection. The deleted sequences may be re-introduced into BCG to improve the efficacy of vaccination. Alternatively, the genetic sequence that corresponds to the deletion(s) are deleted from M. bovis or M. tubercuosis to attenuate the pathogenic bacteria.
摘要翻译：在分枝杆菌分离株中鉴定了特异性遗传缺失，包括分离株之间的结核分枝杆菌基因组序列的变异，以及与M.tb相比在BCG中存在的许多缺失。这些缺失被用作区分病原菌和无毒菌株的标记物，并且作为特异性M.tb菌株的标记物。对BCG疫苗株特异性的缺失可用于确定阳性结核菌素皮肤试验是否表明实际的结核病感染。可将经删除的序列重新引入BCG以提高疫苗接种的效力。或者，对应于缺失的遗传序列从牛分枝杆菌或结核分枝杆菌中缺失，以减毒病原菌。

5. 发明授权

US07188567B1 Gas generation system 失效
标题翻译：气体发生系统
公开(公告)号：US07188567B1
公开(公告)日：2007-03-13
申请号：US10130191
申请日：2000-11-10
申请人： John R. Italiane , James M. Styner , Andrew C. Nguyen , Gary S. Gregg , Gary F. Holland , Michael A. Wilson
发明人： John R. Italiane , James M. Styner , Andrew C. Nguyen , Gary S. Gregg , Gary F. Holland , Michael A. Wilson
IPC分类号： C06D5/00
CPC分类号： C06D5/06 , B60R21/264 , B60R2021/2633
摘要： A gas generator (24; 140) may be used in an inflatable member system (20) which includes an inflatable member (22) expandable from a stowed condition to a deployed condition. The generator may include a flexible container (30; 150) within the inflatable member, a gas generant (28; 148), initially located within the flexible container, and an initiator (34). A propagating member (60; 142) may be located within the container to permit the initiator to initiate the generant upon triggering of the initiator to inflate the inflatable member from stowed to deployed conditions. A sustainer (44; 152; 156) may be provided to sustain the gas generation and may be positioned within a generator housing upstream of the propagating member or at or adjacent the downstream end of the propagating member.
摘要翻译：气体发生器（24; 140）可以用在可膨胀构件系统（20）中，该系统包括从收起状态扩展到展开状态的可膨胀构件（22）。发生器可以包括可充气构件内的柔性容器（30; 150），最初位于柔性容器内的气体发生剂（28; 148）和起动器（34）。传播构件（60; 142）可以位于容器内，以允许引发器在触发引发器时起动发生器，以使可充气构件从收起的状态充满到展开状态。可以提供维持器（44; 152; 156）以维持气体产生并且可以位于传播构件上游的发生器壳体内，或位于传播构件的下游端处或邻近传播构件的下游端。

6. 发明授权

US06291190B1 Molecular differences between species of the M. tuberculosis complex 失效
标题翻译：结核分枝杆菌菌种之间的分子差异
公开(公告)号：US06291190B1
公开(公告)日：2001-09-18
申请号：US09318191
申请日：1999-05-25
申请人： Marcel Behr , Peter Small , Gary Schoolnik , Michael A. Wilson
发明人： Marcel Behr , Peter Small , Gary Schoolnik , Michael A. Wilson
IPC分类号： G01N3353
CPC分类号： C12Q1/689 , C12Q2600/156
摘要： Specific genetic deletions are identified in mycobacteria isolates, including variations in the M. tuberculosis genome sequence between isolates, and numerous deletion present in BCG as compared to M. tb. These deletions are used as markers to distinguish between pathogenic and avirulent strains, and as a marker for particular M. tb isolates. Deletions specific to vaccine strains of BCG are useful in determining whether a positive tuberculin skin test is indicative of actual tuberculosis infection. The deleted sequences may be re-introduced into BCG to improve the efficacy of vaccination. Alternatively, the genetic sequence that corresponds to the deletion(s) are deleted from M. bovis or M. tuberculosis to attenuate the pathogenic bacteria.
摘要翻译：在分枝杆菌分离物中鉴定特异性遗传缺失，包括分离株之间的结核分枝杆菌基因组序列的变异，以及与M.bb相比在BCG中存在的许多缺失。这些缺失被用作区分病原菌和无毒菌株的标记物，并且作为特异性M.tb菌株的标记物。对BCG疫苗株特异性的缺失可用于确定阳性结核菌素皮肤试验是否表明实际的结核病感染。可将经删除的序列重新引入BCG以提高疫苗接种的效力。或者，对应于缺失的遗传序列从牛分枝杆菌或结核分枝杆菌中缺失，以减毒病原菌。

7. 发明授权

US5278462A Threshold crossover detector with improved digital noise rejection 失效
标题翻译：具有改进的数字噪声抑制的阈值交叉检测器
公开(公告)号：US5278462A
公开(公告)日：1994-01-11
申请号：US873253
申请日：1992-04-24
申请人： Michael A. Wilson
发明人： Michael A. Wilson
IPC分类号： H03K5/08 , H03K5/1536 , H03K5/153
CPC分类号： H03K5/08 , H03K5/1536
摘要： The detector applies an analog input signal through respectively positive and negative offset voltages to the inputs of two comparators, one of which produces a first output signal as the input signal passes beyond a predetermined minimum voltage in the positive going direction, and the other of which produces a second output signal when the input voltage exceeds a minimum predetermined value in a negative going direction. The input signal is also applied directly to the input of a third comparator the output of which produces a third signal each time the input signal crosses over zero voltage in a positive going direction. The first and second comparator output signals are applied to the reset and set terminals, respectively, of a first flip flop. The output of this first flip flop, and the output of the third comparator are applied through an AND gate to the set terminal of a second flip flop. The second flip flop produces at its output a digital signal precisely at the time that a signal is produced at the output of the third comparator, provided the outputs of the first and second comparators have been successively generated in the cycle of the input voltage immediately preceding the output signal of the third comparator.
摘要翻译：检测器通过分别的正和负偏移电压将模拟输入信号施加到两个比较器的输入端，其中一个输入信号随着输入信号在正向上超过预定最小电压而产生第一输出信号，另一个当输入电压在负方向上超过最小预定值时产生第二输出信号。输入信号也直接施加到第三比较器的输入，第三比较器的输出在每次输入信号在正向运行方向上跨过零电压时产生第三信号。第一和第二比较器输出信号分别施加到第一触发器的复位和设置端子。该第一触发器的输出和第三比较器的输出通过与门施加到第二触发器的设定端。第二触发器在其输出处产生数字信号，在第三比较器的输出处产生信号时，只要第一和第二比较器的输出在紧接着的输入电压的周期中连续生成第三比较器的输出信号。

8. 发明授权

US4909549A Composition and process for inflating a safety crash bag 失效
标题翻译：充气安全碰撞袋的组成和过程
公开(公告)号：US4909549A
公开(公告)日：1990-03-20
申请号：US278848
申请日：1988-12-02
申请人： Donald R. Poole , Michael A. Wilson
发明人： Donald R. Poole , Michael A. Wilson
IPC分类号： B60R21/26 , B60R21/30 , B64D25/02 , C06D5/00 , C06D5/06
CPC分类号： C06D5/06 , B60R21/30
摘要： Composition and process for inflating an automobile or aircraft safety crash bag comprising igniting a pyrotechnic composition to generate a gas which is admixed with air by means of an aspirating venturi which results in substantially non-toxic products which are thereafter utilized to inflate said crash bag.

9. 发明授权

US07886787B1 Golf grip cover 有权
标题翻译：高尔夫手柄盖
公开(公告)号：US07886787B1
公开(公告)日：2011-02-15
申请号：US12283518
申请日：2008-09-12
申请人： Michael A. Wilson
发明人： Michael A. Wilson
IPC分类号： A63B57/00 , A63B53/00
CPC分类号： A63B60/36 , A63B53/14 , A63B57/00
摘要： A cover for the grip area of golf clubs to keep them dry and protected from the elements is herein disclosed, preferably comprising a neoprene covering in the shape of a tube with the approximate dimensions of twelve (12) to twenty (20) inches long and a diameter of two (2) inches. A first end of the tube is sealed, while a second end is furnished with a flexible membrane which seals it against the club shaft. The closed end is provided with a hook to allow the cover to be hung along with a club, thereby providing a means for the cover to be placed over the grip end of a golf club in much the same manner as a sock. This not only extends the life of the club and grip, but provides the golfer with enhanced performance due to the decreased risk of slippage during play, particularly during wet conditions.
摘要翻译：本文公开了用于保持其干燥和保护元件的高尔夫球杆的握持区域的盖，优选地包括具有十二（12）至二十（20）英寸长的尺寸的管的形状的氯丁橡胶覆盖物，并且直径为2（2）英寸。管的第一端被密封，而第二端设置有柔性膜，其将其密封抵靠球杆杆杆。封闭端设置有钩子，以允许盖子与杆杆一起悬挂，从而提供了一种用于以与袜子大致相同的方式将盖子放置在高尔夫球杆的握持端上的装置。这不仅延长了球杆的使用寿命，而且提高了高尔夫球手的性能，因为在打滑期间打滑的风险降低，特别是在潮湿条件下。

10. 发明授权

US07758634B2 Bifurcated stent and delivery system 失效
标题翻译：分叉支架和分娩系统
公开(公告)号：US07758634B2
公开(公告)日：2010-07-20
申请号：US11726144
申请日：2007-03-21
申请人： Gregory G. Brucker , Enrique Malaret , Todd Hall , David Byrd , Gerald Hubbs , Gregory Furnish , Josh Barber , Indaka Gunasekara , Benjamin Morris , Valerie Futral , Sava A. Chernomordik , William C. Mers Kelly , William A. Reuss , Simon Furnish , Michael A. Wilson , Hacene Bouadi , John C. Muskivitch , Matthew L. Pease , David A. Rahdert , Travis Rowe , Gregory M. Ruhf , Brandon G. Walsh , Thomas Banks , Russ Redmond , Claude Vidal
发明人： Gregory G. Brucker , Enrique Malaret , Todd Hall , David Byrd , Gerald Hubbs , Gregory Furnish , Josh Barber , Indaka Gunasekara , Benjamin Morris , Valerie Futral , Sava A. Chernomordik , William C. Mers Kelly , William A. Reuss , Simon Furnish , Michael A. Wilson , Hacene Bouadi , John C. Muskivitch , Matthew L. Pease , David A. Rahdert , Travis Rowe , Gregory M. Ruhf , Brandon G. Walsh , Thomas Banks , Russ Redmond , Claude Vidal
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/954 , A61F2/958 , A61F2/966 , A61F2/97 , A61F2002/061 , A61F2002/821 , A61F2002/9583 , A61F2250/006
摘要： A bifurcated stent includes a first stent section and a second stent section. The first stent section is balloon expandable, has an unexpanded configuration, an expanded configuration, and a tubular wall defining a secondary opening. The secondary stent section is self-expanding and an end of the secondary stent section is engaged to a portion of the tubular wall of the primary stent section defining the secondary opening. The secondary stent section has an unexpanded configuration with a first length and an expanded configuration with a second length where the first length is less than the second length. The secondary stent section is expanded to the expanded configuration after the primary stent section is expanded to the expanded configuration. The secondary stent section forms a portion of the tubular wall of the primary stent section in the unexpanded configuration.
摘要翻译：分支支架包括第一支架部分和第二支架部分。第一支架部分是球囊可膨胀的，具有未膨胀的构造，膨胀的构型和限定次级开口的管状壁。辅助支架部分是自膨胀的，并且次级支架部分的端部接合到限定第二开口的主支架部分的管状壁的一部分。次级支架部分具有第一长度和第二长度的膨胀构造的未膨胀构型，其中第一长度小于第二长度。在将主支架部分扩展到扩张构型之后，将二次支架部分扩大到扩张构型。辅助支架部分以未展开的构型形成主支架部分的管状壁的一部分。

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