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1. 发明申请

US20090286694A1 NUCLEIC ACID ARRAY WITH RELEASEABLE NUCLEIC ACID PROBES 审中-公开
标题翻译：核酸序列与可释放的核酸探针
公开(公告)号：US20090286694A1
公开(公告)日：2009-11-19
申请号：US12511751
申请日：2009-07-29
申请人： Gafur Zainiev , Inlik Zainieva
发明人： Gafur Zainiev , Inlik Zainieva
IPC分类号： C40B30/04 , C40B40/08
CPC分类号： B01L3/5025 , B01J2219/00358 , B01J2219/00644 , B01J2219/00653 , B01J2219/00722 , B01L3/5027 , B01L3/502753 , B01L3/50851 , B01L7/52 , B01L2300/069 , C12Q1/6813 , C12Q2565/125 , C12Q2547/107 , C12Q2537/149
摘要： A process is provided for identifying a complementary target nucleic acid. The process includes the hybridization of a nucleic acid probe to a carrier to form a nucleic acid probe-carrier complex. The complex is placed in a compartment bounded by a media permeable to the nucleic acid probe and exclusive of both the carrier and the complex. The complex is then denatured, with the nucleic acid probe transported through the media and into contact with the target nucleic acid. The nucleic acid probe hybridizes to the complementary target nucleic acid to yield a probe-target double stranded complex. A non-complementary nucleic acid probe, independent probe-target complex is returned to the compartment and given an opportunity to rehybridize to the carrier. A determination as to whether at least one of the complementary target nucleic acid or the carrier is present as a complex provides information as to probe sequences complementary to the target nucleic acid.
摘要翻译：提供了用于鉴定互补靶核酸的方法。该方法包括将核酸探针与载体杂交以形成核酸探针 - 载体复合物。将复合物置于由可渗透核酸探针的介质限定的区域中，并且不包括载体和复合物两者。然后将复合物变性，核酸探针通过培养基传输并与靶核酸接触。核酸探针与互补靶核酸杂交以产生探针 - 靶双链复合物。将非互补核酸探针，独立的探针 - 靶复合物返回到隔室，给予再载体载体的机会。作为复合物存在至少一种互补靶核酸或载体的确定提供了与靶核酸互补的探针序列的信息。

2. 发明申请

US20080044822A1 NUCLEIC ACID ARRAY WITH RELEASEABLE NUCLEIC ACID PROBES 审中-公开
标题翻译：核酸序列与可释放的核酸探针
公开(公告)号：US20080044822A1
公开(公告)日：2008-02-21
申请号：US11465875
申请日：2006-08-21
申请人： Gafur Zainiev , Inlik Zainieva
发明人： Gafur Zainiev , Inlik Zainieva
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6813 , B01J2219/00358 , B01J2219/00644 , B01J2219/00653 , B01J2219/00722 , B01L3/5027 , C12Q2565/125 , C12Q2547/107 , C12Q2537/149
摘要： A process is provided for identifying a complementary target nucleic acid. The process includes the hybridization of a nucleic acid probe to a carrier to form a nucleic acid probe-carrier complex. The complex is placed in a compartment bounded by a media permeable to the nucleic acid probe and exclusive of both the carrier and the complex. The complex is then denatured, with the nucleic acid probe transported through the media and into contact with the target nucleic acid. The nucleic acid probe hybridizes to the complementary target nucleic acid to yield a probe-target double stranded complex. A non-complementary nucleic acid probe, independent probe-target complex is returned to the compartment and given an opportunity to rehybridize to the carrier. A determination as to whether at least one of the complementary target nucleic acid or the carrier is present as a complex provides information as to probe sequences complementary to the target nucleic acid.
摘要翻译：提供了用于鉴定互补靶核酸的方法。该方法包括将核酸探针与载体杂交以形成核酸探针 - 载体复合物。将复合物置于由可渗透核酸探针的介质限定的区域中，并且不包括载体和复合物两者。然后将复合物变性，核酸探针通过培养基传输并与靶核酸接触。核酸探针与互补靶核酸杂交以产生探针 - 靶双链复合物。将非互补核酸探针，独立的探针 - 靶复合物返回到隔室，给予再载体载体的机会。作为复合物存在至少一种互补靶核酸或载体的确定提供了与靶核酸互补的探针序列的信息。

3. 发明申请

US20070276408A1 Suturing Devices and Methods 审中-公开
标题翻译：缝合装置和方法
公开(公告)号：US20070276408A1
公开(公告)日：2007-11-29
申请号：US10570521
申请日：2004-09-02
申请人： Charles Filipi , Douglas Cornet , Gafur Zainiev , Inlik Zainieva , Vladimir Gerasimov , Valeriy Prushinskiy , Marina Prushinskaya
发明人： Charles Filipi , Douglas Cornet , Gafur Zainiev , Inlik Zainieva , Vladimir Gerasimov , Valeriy Prushinskiy , Marina Prushinskaya
IPC分类号： A61B17/10
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0491 , A61B17/1114 , A61B2017/00296 , A61B2017/0409 , A61B2017/0416 , A61B2017/0417 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496
摘要： Disclosed is a T-fastener delivery device. The device includes a belt and a pusher rod. The belt includes a plurality of slots for holding a plurality of T-bars substantially parallel to one another in a side-by-side arrangement; and the belt is moveable such that the slots can be sequentially aligned with the pusher rod. Also disclosed are methods for creating a gastric pouch in the stomach of an obese patient and methods for reducing lower esophageal sphincter distraction with gastric filling in a subject. Suturing systems are also disclosed One suturing system includes a plurality of T-fasteners and a continuous suture connecting the plurality of T-fasteners. The T-fastener comprises a cylindrical bar having a filament loop attached thereto substantially at the cylindrical bar's axial midpoint, and the continuous suture slidably passes through the T-fasteners' filament loops. Another suturing system includes a plurality of T-fasteners; and a continuous suture connecting the plurality of T-fasteners. The T-fastener comprises two cylindrical bars connected by a filament, and the continuous suture slidably passes through a loop formed by the T-fasteners' filaments.
摘要翻译：公开了一种T型紧固件输送装置。该装置包括带和推杆。所述带包括多个槽，所述多个槽用于以并排布置彼此基本平行地保持多个T形杆; 并且带可移动，使得槽可以顺序地与推杆对准。还公开了用于在肥胖患者的胃中产生胃袋的方法以及用于在受试者中用胃灌注减少食管下括约肌分心的方法。还公开了缝合系统一个缝合系统包括多个T形紧固件和连接多个T形紧固件的连续缝合线。 T型紧固件包括一个圆柱形杆，其具有大致在圆柱形杆的轴向中点附接的细丝环，并且连续缝合线可滑动地穿过T形紧固件的细丝环。另一缝合系统包括多个T形紧固件; 以及连接多个T形紧固件的连续缝合线。 T形紧固件包括由细丝连接的两个圆柱形杆，并且连续缝合线可滑动地穿过由T形紧固件的细丝形成的环。

4. 发明申请

US20080227212A1 PROCESS FOR IDENTIFYING EXISTENCE OF SINGLE NUCLEOTIDE POLYMORPHISM WITHOUT DNA SEQUENCING 审中-公开
标题翻译：没有DNA序列识别单核多核苷酸存在的方法
公开(公告)号：US20080227212A1
公开(公告)日：2008-09-18
申请号：US12049679
申请日：2008-03-17
申请人： Gafur Zainiev , Inlik Zainiev , Timur Zainiev
发明人： Gafur Zainiev , Inlik Zainiev , Timur Zainiev
IPC分类号： G01N33/00
CPC分类号： C12Q1/6827 , Y10T436/143333 , C12Q2565/629 , C12Q2527/137
摘要： A process for detecting the presence of a mutation in an oligonucleotide strand such as a DNA strand from a gene without the need for DNA sequencing is provided. The inventive process provides a rapid pre-test to screen for the presence or absence of a mutation in a target gene of a subject to determine whether laborious sequencing protocols are required to further characterize a mutation. The inventive process provides a rapid screening protocol for identifying and detecting a genetic mutation in a patient who presents with a disease
摘要翻译：提供了检测寡核苷酸链中的突变的存在的方法，例如来自基因的DNA链，而不需要进行DNA测序。本发明的方法提供了快速预检测以筛选受试者靶基因中突变的存在或不存在，以确定是否需要费力的测序方案来进一步表征突变。本发明的方法提供用于鉴定和检测患有疾病的患者中的遗传突变的快速筛选方案

5. 发明授权

US07423367B2 Design of high power pulsed flash lamps 失效
标题翻译：大功率脉冲闪光灯的设计
公开(公告)号：US07423367B2
公开(公告)日：2008-09-09
申请号：US11466798
申请日：2006-08-24
申请人： Robert M. Lantis , Boris Zlotin , Peter Ulan , Vladimir Proseanic , Gafur Zainiev
发明人： Robert M. Lantis , Boris Zlotin , Peter Ulan , Vladimir Proseanic , Gafur Zainiev
IPC分类号： H01J19/12
CPC分类号： H01J61/80 , H01J5/48 , H01J61/073 , H01J61/30 , H01J61/33 , H01J61/34 , H01J61/50 , H01J61/52 , H01J61/90 , H01J61/95
摘要： Broadband output high power pulsed flash lamps are useful in many applications, and when specifically optimized, can become an excellent source of ultraviolet (UV) light, which is particularly useful for photo-chemically-induced materials processing applications. Multiple factors involved with the production of high-energy light pulses can in certain cases adversely affect the ultraviolet lamp operation, thereby resulting in the development of micro cracks in lamp envelopes and subsequent limitation in lamp lifetime. Similar factors can be responsible for an increased absorption of UV radiation by lamp components and degradation of lamp efficiency. This invention describes new pulsed flash lamp designs that enable a new generation of high power and performance as required by, for example, many large-scale photo-processing applications. This invention uniquely and advantageously mitigates the development of micro-cracks and failure, and produces dramatically improved electrical efficiency, stability of lamp optical characteristics, and service lifetime.
摘要翻译：宽带输出高功率脉冲闪光灯在许多应用中是有用的，当被特别优化时，可以成为紫外线（UV）光的优良来源，这对于光化学诱导的材料处理应用尤其有用。与高能量光脉冲相关的多个因素在某些情况下可能对紫外线灯的操作产生不利影响，从而导致灯泡内的微裂纹的发展和灯寿命的限制。类似的因素可能导致灯组件对UV辐射的吸收增加和灯效率的降低。本发明描述了新的脉冲闪光灯设计，其能够实现例如许多大规模照相处理应用所要求的新一代高功率和性能。本发明独特且有利地减轻微裂纹和破裂的发展，并且产生显着提高的电效率，灯的光学特性的稳定性和使用寿命。

6. 发明申请

US20070014921A1 Method of applying a design to a surface 有权
标题翻译：将设计应用于表面的方法
公开(公告)号：US20070014921A1
公开(公告)日：2007-01-18
申请号：US11447817
申请日：2006-06-06
申请人： James Kimball , Eric Minor , Ketan Shah , Marcia Santaga , Daniel Bullis , Gafur Zainiev , Douglas Rodenkirch
发明人： James Kimball , Eric Minor , Ketan Shah , Marcia Santaga , Daniel Bullis , Gafur Zainiev , Douglas Rodenkirch
IPC分类号： B05D5/00 , B05D3/02 , B29C71/04
CPC分类号： B44C1/105 , B05C17/06 , B41M7/0072 , B41M7/009 , B41N1/242 , B41N1/248 , B44C1/18 , B44C1/20 , B44C3/02 , B44D2/007 , B44D5/00 , C09D5/008 , C09D11/0235 , C11D3/37 , C11D3/3715 , C11D3/3726 , C11D3/3749 , C11D11/0058 , C11D11/007 , D06P1/0012 , D06P1/0016 , D06P1/44 , D06P1/52 , D06P1/5264 , D06P1/5271 , D06P1/54 , D06P1/613 , D06P5/001 , D06Q1/00 , D06Q1/06 , D06Q1/10 , Y10T156/10 , Y10T428/249921 , Y10T428/25 , Y10T428/253 , Y10T428/254 , Y10T428/28 , Y10T428/31504
摘要： Compositions, methods, apparatuses, kits, and combinations are described for permanently or temporarily re-designing, decorating, and/or re-coloring a surface. The compositions useful in the present disclosure include a décor product that is formulated to be applied and affixed to a surface. If desired, the décor product may be substantially removed from the surface before being affixed thereto. If a user desires to remove the décor product, the décor product is formulated to be removed by a number of methods including, for example, vacuuming, wet extraction, chemical application, and the like. If the user desires to affix the décor product to the surface in a permanent or semi-permanent manner, the décor product may be affixed to the surface by applying energy thereto in the form of, for example, heat, pressure, emitted waves, an emitted electrical field, a magnetic field, and/or a chemical. The décor product may also be utilized in the form of a kit or in conjunction with a design device, such as a stencil, to control the application of the décor product to create, for example, a pattern on the surface.
摘要翻译：描述了组合物，方法，装置，试剂盒和组合，用于永久地或暂时地重新设计，装饰和/或重新着色表面。用于本公开的组合物包括配制成施用并固定在表面上的装饰产品。如果需要，装饰产品可以在被固定到其之前基本上从表面上移除。如果用户想要去除装饰产品，则将该装饰产品配制成通过多种方法除去，包括例如抽真空，湿法萃取，化学应用等。如果用户希望以永久或半永久的方式将装饰产品粘贴到表面上，则可以通过以例如热，压力，发射波的形式施加能量来将装饰产品固定到表面上发射电场，磁场和/或化学物质。装饰产品还可以以套件的形式或与设计装置（例如模版）结合使用，以控制装饰产品的应用以产生例如表面上的图案。

7. 发明申请

US20080241836A1 PROCESS FOR SELF-ASSEMBLY OF STRUCTURES IN A LIQUID 审中-公开
标题翻译：液体中自组织的方法
公开(公告)号：US20080241836A1
公开(公告)日：2008-10-02
申请号：US11927891
申请日：2008-03-31
申请人： Gafur Zainiev , Inlik Zainiev , Timur Zainiev
发明人： Gafur Zainiev , Inlik Zainiev , Timur Zainiev
IPC分类号： C12Q1/68 , C12P19/34 , C12M1/00
CPC分类号： C12P19/34 , B01L3/5027 , C12Q1/6869 , C12Q2565/501 , C12Q2521/101
摘要： A process and apparatus for self-assembling a number of elements and determining their sequence is provided. In the field of DNA analysis, an iterative process is disclosed wherein an apparatus with a set of reaction chambers in which a species of recognition element nucleotides are differentially added and subjected to a polymerization reaction allows recognition of which species is next in sequence on a template strand by the effect that synthesis has on a detecting template as measured by a detector in a detection area. Stepwise addition of the identified species then determines if an element repeat exists. The process is repeated until the entire structure is complete and the sequence identified.
摘要翻译：提供了一种用于自组装多个元件并确定其顺序的过程和装置。在DNA分析领域中，公开了一种迭代方法，其中具有一组反应室的装置，其中识别元件核苷酸的种类被差异添加并进行聚合反应允许在模板上依次识别下一个物种通过检测区域中的检测器测量的合成对检测模板的影响。逐步添加所识别的物种然后确定元素重复是否存在。重复该过程，直到整个结构完成并确定序列。

8. 发明申请

US20080044821A1 NUCLEIC ACID ARRAY HAVING FIXED NUCLEIC ACID ANTI-PROBES AND COMPLEMENTARY FREE NUCLEIC ACID PROBES 审中-公开
标题翻译：具有固定核酸抗原探针和完全免费的核酸探针的核酸阵列
公开(公告)号：US20080044821A1
公开(公告)日：2008-02-21
申请号：US11465870
申请日：2006-08-21
申请人： Gafur Zainiev , Inlik Zainiev
发明人： Gafur Zainiev , Inlik Zainiev
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6837 , C12Q2537/161
摘要： A process for identifying a complementary nucleic acid probe to a target nucleic acid involves forming an array of spots where each spot of the array has an immobilized nucleic acid anti-probe to which is hybridized a nucleic acid probe. The array of the anti-probe-probe complex is denatured. The nucleic acid probes are then moved into a target chamber that includes a target nucleic acid. Hybridization conditions are established to form double-stranded complexation between the target nucleic acid and nucleic acid probes in instances where the target nucleic acid has a sequence complementary. The nucleic acid probes noncomplementary to the target nucleic acid are allowed to rehybridize with anti-probes. Determining whether the anti-probe spots exposed to nucleic acid probes noncomplementary to the target nucleic acid are single stranded after exposure to noncomplementary nucleic acid probes provides information as to target nucleic acid sequence.
摘要翻译：用于鉴定靶核酸的互补核酸探针的方法包括形成阵列阵列，其中阵列的每个点具有与核酸探针杂交的固定的核酸抗探针。抗探针 - 探针复合物的阵列变性。然后将核酸探针移动到包括靶核酸的靶室中。建立杂交条件以在目标核酸具有序列互补性的情况下在靶核酸和核酸探针之间形成双链复合。允许与靶核酸不互补的核酸探针用抗探针重新杂化。确定在暴露于非互补核酸探针之后，暴露于与靶核酸不互补的核酸探针的抗探针点是单链提供关于靶核酸序列的信息。

9. 发明授权

US06458456B1 Composite fiber for absorptive material construction 失效
标题翻译：用于吸收材料结构的复合纤维
公开(公告)号：US06458456B1
公开(公告)日：2002-10-01
申请号：US09532613
申请日：2000-03-22
申请人： Gafur Zainiev , Vladimir Gerasimov , Boris Zlotin , Michael L. Weiner
发明人： Gafur Zainiev , Vladimir Gerasimov , Boris Zlotin , Michael L. Weiner
IPC分类号： D05F600
CPC分类号： A61F13/47 , A61F13/02 , A61F13/2051 , A61F13/42 , A61F13/49 , A61F13/53 , A61F13/537 , A61F13/538 , A61F13/5605 , A61F13/72 , A61F2013/15487 , A61F2013/530897 , D01D5/24 , Y10T428/2924 , Y10T428/2935 , Y10T428/2975
摘要： An absorbent fiber is constructed to include a hydrophobic exterior and a hydrophilic interior for use in various absorbent constructions as an absorbent, capture and entrain liquids and attendant odors.
摘要翻译：吸收性纤维被构造成包括疏水性外部和亲水性内部，用于各种吸收性结构中作为吸收剂，捕获和夹带液体和伴随的气味。

10. 发明授权

US08153403B1 Process for identifying existence of single nucleotide polymorphism without DNA sequencing 有权
标题翻译：识别单核苷酸多态性存在而不进行DNA测序的方法
公开(公告)号：US08153403B1
公开(公告)日：2012-04-10
申请号：US12714974
申请日：2010-03-01
申请人： Gafur Zainiev , Inlik Zainiev , Timur Zainiev
发明人： Gafur Zainiev , Inlik Zainiev , Timur Zainiev
IPC分类号： C12P19/34 , C12Q1/68
CPC分类号： C12Q1/6827 , C12Q2565/629 , C12Q2527/137
摘要： A process for detecting the presence of a mutation in an oligonucleotide strand such as a DNA strand from a gene without the need for DNA sequencing is provided. The inventive process provides a rapid pre-test to screen for the presence or absence of a mutation in a target gene of a subject to determine whether laborious sequencing protocols are required to further characterize a mutation. The inventive process provides a rapid screening protocol for identifying and detecting a genetic mutation in a patient who presents with a disease.
摘要翻译：提供了检测寡核苷酸链中的突变的存在的方法，例如来自基因的DNA链，而不需要进行DNA测序。本发明的方法提供了快速预检测以筛选受试者靶基因中突变的存在或不存在，以确定是否需要费力的测序方案来进一步表征突变。本发明的方法提供用于鉴定和检测患有疾病的患者中的遗传突变的快速筛选方案。

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