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1. 发明申请

US20060029756A1 Catheter balloon formed of ePTFE and a diene polymer 审中-公开
公开(公告)号：US20060029756A1
公开(公告)日：2006-02-09
申请号：US11198623
申请日：2005-08-05
申请人： Florencia Lim , Chi Long , Charles Claude , Jeong Lee , Srinivasan Sridharan , Fernando Gonzalez , Edwin Wang
发明人： Florencia Lim , Chi Long , Charles Claude , Jeong Lee , Srinivasan Sridharan , Fernando Gonzalez , Edwin Wang
IPC分类号： B32B27/32
CPC分类号： A61M25/1034 , A61L29/041 , A61L29/085 , A61L29/126 , A61M25/1006 , A61M25/1025 , A61M25/1029 , A61M2025/1075 , Y10T428/13 , Y10T428/1334 , Y10T428/1352 , Y10T428/1376 , Y10T428/1386 , Y10T428/139 , Y10T428/1393 , C08L27/18
摘要： A catheter balloon formed of a polymeric material such as expanded polytetrafluoroethylene (ePTFE) bonded to a second layer formed of a low tensile set polymer and/or impregnated with a low tensile set polymer. In a presently preferred embodiment, the low tensile set polymer is an elastomer selected from the group consisting of a silicone-polyurethane copolymer and a diene polymer. The low tensile set polymer has high strength, low modulus, high elongation, and low tensile set, to provide improved balloon performance. The diene or silicone-polyurethane has a low tensile set, which facilitates deflation of the balloon to a low profile deflated configuration. One aspect of the invention provides improved attachment of the diene to the ePTFE. In one embodiment, the second layer is formed of a diene mixed with a bonding promoter such as a vulcanizing agent which is covalently bonded to the diene.

2. 发明申请

US20070038240A1 Catheter balloon having impregnated balloon skirt sections 有权
标题翻译：导管球囊已浸渍气囊裙部
公开(公告)号：US20070038240A1
公开(公告)日：2007-02-15
申请号：US11585071
申请日：2006-10-23
申请人： Florencia Lim , Jeong Lee , Edwin Wang
发明人： Florencia Lim , Jeong Lee , Edwin Wang
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61L29/06 , A61L29/085 , A61M2025/1075 , C08L79/02 , C08L75/04
摘要： A balloon catheter and a method of making a balloon catheter, having a balloon with a first layer and a second layer, the first layer having at least one impregnated section impregnated with a polymeric material compatible with a polymeric material forming the catheter shaft. At least a portion of the impregnated section is fusion bonded to the shaft. In a presently preferred embodiment, the impregnated section is adjacent to a section of the first layer which is not impregnated with the compatible polymeric material. The impregnated section provides improved bonding of the balloon to the catheter shaft while minimizing the effect of the bond on catheter performance characteristics such as profile and flexibility.
摘要翻译：气囊导管和制造球囊导管的方法，具有具有第一层和第二层的气囊，所述第一层具有浸渍有与形成导管轴的聚合物材料相容的聚合材料的至少一个浸渍部分。浸渍部分的至少一部分熔合在轴上。在目前优选的实施方案中，浸渍的部分邻近第一层的不被相容的聚合物材料浸渍的部分。浸渍部分提供了球囊与导管轴的改善的粘合，同时最小化粘合对导管性能特征如轮廓和柔性的影响。

3. 发明申请

US20060030874A1 Catheter with a polyimide distal tip 有权
公开(公告)号：US20060030874A1
公开(公告)日：2006-02-09
申请号：US11237376
申请日：2005-09-28
申请人： Jeong Lee , Edwin Wang
发明人： Jeong Lee , Edwin Wang
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61L29/085 , A61L2420/08 , A61M25/001 , A61M25/0045 , A61M25/0069 , A61M2025/1093 , C08L79/08 , C08L77/00 , C08L77/12 , C08L75/04
摘要： A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.

4. 发明申请

US20080021495A1 MRI VISIBLE CATHETER BALLOON 审中-公开
标题翻译： MRI可见气囊
公开(公告)号：US20080021495A1
公开(公告)日：2008-01-24
申请号：US11828921
申请日：2007-07-26
申请人： Jeong Lee , Edwin Wang , Roseminda White , Jose Romero
发明人： Jeong Lee , Edwin Wang , Roseminda White , Jose Romero
IPC分类号： A61M29/00
CPC分类号： A61F2/95 , A61B2090/3954 , A61L29/106 , A61L29/126 , A61L29/18 , A61M25/10 , A61M25/1029 , A61M25/104 , A61M2025/1031 , A61M2025/1075 , A61M2025/1079
摘要： Medical devices or components thereof, and particularly intracorporeal devices for therapeutic or diagnostic uses, which are formed at least in part of a polymeric material and a ferromagnetic or paramagnetic material, so that the medical device or component thereof is visible on magnetic resonance imaging (MRI) scans. In one embodiment, the medical device is a balloon catheter having an MRI visible balloon. In a presently preferred embodiment, there is an insufficient amount of the ferromagnetic or paramagnetic material within a wall of the balloon or coated onto a wall of the balloon to make the balloon radiopaque.
摘要翻译：医疗器械或其组件，特别是用于治疗或诊断用途的体内器件，其至少部分地由聚合物材料和铁磁性或顺磁性材料形成，使得医疗器械或其组件在磁共振成像（MRI））扫描。在一个实施例中，医疗装置是具有MRI可见气囊的气囊导管。在目前优选的实施方案中，在球囊的壁内存在不足量的铁磁性或顺磁性材料，或涂覆在气球的壁上，以使气球不透射线。

5. 发明申请

US20050240214A1 Catheter having an improved distal tip 有权
标题翻译：导管具有改进的远端
公开(公告)号：US20050240214A1
公开(公告)日：2005-10-27
申请号：US11172543
申请日：2005-06-29
申请人： Edwin Wang , Roseminda White , Jeong Lee , Tim Kitchen
发明人： Edwin Wang , Roseminda White , Jeong Lee , Tim Kitchen
IPC分类号： A61F2/958 , A61M25/00 , A61M29/00
CPC分类号： A61M25/0069 , A61M25/001 , A61M25/10 , A61M2025/1093
摘要： An elongated balloon catheter having a distal tip member on the distal end of the catheter and having a sleeve surrounding and secured at least to the proximal end of the distal tip member.
摘要翻译：一种细长的气囊导管，其具有在导管的远端上的远侧末端构件，并且具有围绕并固定至远侧末端构件的近端的套筒。

6. 发明申请

US20050240213A1 Catheter with a multilayered shaft section having a polyimide layer 有权
标题翻译：具有具有聚酰亚胺层的多层轴部的导管
公开(公告)号：US20050240213A1
公开(公告)日：2005-10-27
申请号：US11038971
申请日：2005-01-18
申请人： Jeong Lee , Edwin Wang , Roseminda White
发明人： Jeong Lee , Edwin Wang , Roseminda White
IPC分类号： A61F2/958 , A61L29/08 , A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/0045 , A61L29/085 , A61M25/0009 , A61M25/104 , C08L77/12 , C08L75/04 , C08L79/08
摘要： A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.
摘要翻译：一种具有多层轴部的导管，其具有由聚酰亚胺第一材料形成的第一层和由第二材料形成的第二层。在目前优选的实施方案中，聚酰亚胺材料是热固性聚酰亚胺。然而，在替代实施例中，使用热塑性聚酰亚胺。热固性聚酰亚胺具有约400℃的非常高的玻璃化转变温度（Tg）（通过差示扫描量热法测量），以及在导管组件中常用的聚酰胺的加工温度下的优异的尺寸稳定性。结果，在导管的形成和组装过程中，有助于生产具有受控尺寸的薄聚酰亚胺层。聚酰亚胺具有高模量并且提供薄壁且高度可推动的轴部分，而第二层提供扭结阻力。在一个实施方案中，第二材料选自聚酰胺材料和聚氨酯材料。

7. 发明申请

US20050215885A1 MRI visible catheter balloon 审中-公开
公开(公告)号：US20050215885A1
公开(公告)日：2005-09-29
申请号：US11094333
申请日：2005-03-29
申请人： Jeong Lee , Edwin Wang , Roseminda White , Jose Romero
发明人： Jeong Lee , Edwin Wang , Roseminda White , Jose Romero
IPC分类号： A61B19/00 , A61F2/958 , A61L29/10 , A61L29/12 , A61L29/18 , A61M29/02 , A61B5/05
CPC分类号： A61F2/95 , A61B2090/3954 , A61L29/106 , A61L29/126 , A61L29/18 , A61M25/10 , A61M25/1029 , A61M25/104 , A61M2025/1031 , A61M2025/1075 , A61M2025/1079
摘要： Medical devices or components thereof, and particularly intracorporeal devices for therapeutic or diagnostic uses, which are formed at least in part of a polymeric material and a ferromagnetic or paramagnetic material, so that the medical device or component thereof is visible on magnetic resonance imaging (MRI) scans. In one embodiment, the medical device is a balloon catheter having an MRI visible balloon. In a presently preferred embodiment, there is an insufficient amount of the ferromagnetic or paramagnetic material within a wall of the balloon or coated onto a wall of the balloon to make the balloon radiopaque.

8. 发明授权

US08703169B1 Implantable device having a coating comprising carrageenan and a biostable polymer 失效
标题翻译：具有包含角叉菜胶和生物稳定聚合物的涂层的可植入装置
公开(公告)号：US08703169B1
公开(公告)日：2014-04-22
申请号：US11891150
申请日：2007-08-08
申请人： Jeong Lee
发明人： Jeong Lee
IPC分类号： A61F2/00 , A61K31/335 , A61K31/445 , A61K31/497 , A61K31/56 , A61K38/43 , A61P43/00
CPC分类号： A61L31/148 , A61F2/82 , A61F2250/0067 , A61K31/00 , A61L31/10 , A61L31/16 , A61L2300/114 , A61L2300/416 , A61L2300/43 , A61L2300/604 , A61L2300/606 , C08L5/00
摘要： The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
摘要翻译：本发明提供具有包含缓慢溶解性聚合物或材料的涂层的可植入装置及其制造和使用方法。

9. 发明申请

US20070198043A1 Bone marrow aspiration device 审中-公开
标题翻译：骨髓抽吸装置
公开(公告)号：US20070198043A1
公开(公告)日：2007-08-23
申请号：US11360324
申请日：2006-02-22
申请人： Daniel Cox , Eugene Michal , Robert Ainsworth , Gregory Chan , Jeong Lee , Albert Chin , Geoff Willis , Philip Yip
发明人： Daniel Cox , Eugene Michal , Robert Ainsworth , Gregory Chan , Jeong Lee , Albert Chin , Geoff Willis , Philip Yip
IPC分类号： A61B17/34 , A61M5/32 , A61B10/00
CPC分类号： A61B10/025 , A61B10/0283 , A61B34/20 , A61B2010/0208 , A61B2010/0258
摘要： A bone marrow aspiration device is described. In one embodiment, the bone marrow aspiration device includes a central body portion having a proximal end and a distal end, and an outer shaft portion coupled to the distal end of the central body portion. The outer shaft portion also has a distal opening. A first lumen is formed by the central body portion and the outer shaft portion, and the first lumen extends from the proximal end to the distal opening. An aspiration needle is disposed within the first lumen. The aspiration needle has a substantially linear configuration when positioned within the first lumen, and a substantially curved configuration when extended from the distal opening. The aspiration needle is adapted to aspirate liquid bone marrow from a first region of a bone cavity.
摘要翻译：描述骨髓抽吸装置。在一个实施例中，骨髓抽吸装置包括具有近端和远端的中心主体部分，以及联接到中心主体部分的远端的外轴部分。外轴部分还具有远端开口。第一管腔由中心主体部分和外轴部分形成，并且第一内腔从近端延伸到远端开口。抽吸针设置在第一管腔内。当定位在第一内腔内时，抽吸针具有基本线性的构造，并且当从远端开口延伸时具有基本弯曲的构造。抽吸针适于从骨腔的第一区域吸出液体骨髓。

10. 发明申请

US20070100522A1 Method for measuring vertical acceleration and velocity of semi-active suspension system 有权
标题翻译：半主动悬挂系统的垂直加速度和速度测量方法
公开(公告)号：US20070100522A1
公开(公告)日：2007-05-03
申请号：US11264128
申请日：2005-11-02
申请人： Wan Il Kim , Jeong Lee
发明人： Wan Il Kim , Jeong Lee
IPC分类号： B60G17/018
CPC分类号： B60G17/0152 , B60G17/01908 , B60G2400/102 , B60G2500/10 , B60G2500/20 , B60G2600/12 , B60G2600/90
摘要： The present invention relates to a method for measuring a vertical acceleration and a velocity of a semi-active suspension system. Particularly, the present invention provides a method for obtaining a vertical acceleration from vertical accelerations measured from three vertical acceleration sensors of a semi-active suspension system of a vehicle, comprising the steps of: receiving first to third vertical accelerations measured from first to third vertical acceleration sensors; and obtaining a fourth vertical acceleration (Ad) by multiplying the first to third vertical accelerations by correction constants and subsequently summing up them. Therefore, according to the present invention, a fourth vertical acceleration can be obtained by multiplying the three vertical accelerations measured from the three acceleration sensors by the constants for correcting them to accelerations at actually desired damper positions and subsequently summing up them, thereby enabling accurate measurement and correction of the vertical accelerations.
摘要翻译：本发明涉及一种用于测量半主动悬架系统的垂直加速度和速度的方法。特别地，本发明提供一种用于从车辆的半主动悬架系统的三个垂直加速度传感器测量的垂直加速度获得垂直加速度的方法，包括以下步骤：接收从第一至第三垂直测量的第一至第三垂直加速度加速度传感器; 并且通过将第一至第三垂直加速度乘以校正常数并随后将其相加来获得第四垂直加速度（Ad）。因此，根据本发明，通过将从三个加速度传感器测量的三个垂直加速度乘以用于将它们校正到实际期望的阻尼器位置处的加速度的常数并且随后将其相加，可以获得第四垂直加速度，从而使得能够精确测量和垂直加速度的校正。

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