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1. 发明申请

US20100020921A1 SYSTEM AND METHOD FOR GENERATING COMPUTED TOMOGRAPHY IMAGES 有权
标题翻译：用于产生计算机图像的系统和方法
公开(公告)号：US20100020921A1
公开(公告)日：2010-01-28
申请号：US12179298
申请日：2008-07-24
申请人： Fang Frank Dong , Xiaoye Wu , James Walter Leblanc
发明人： Fang Frank Dong , Xiaoye Wu , James Walter Leblanc
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/4028 , A61B6/583 , Y10S378/901
摘要： A computed tomographic imaging system is provided for generating computed tomography images. The computed tomographic system includes a processor configured to access image data encoding X-ray projections at a detector position and a plurality of X-ray source beam focal spot positions and to align pixel values for the projections in a direction of deviation of the positions. The processor is also configured to determine a correction factor for at least one of the projections based upon the aligned pixel values and upon a sum of the projections and to correct the pixel values for the at least one of the projections based upon the correction factor.
摘要翻译：提供计算机断层摄影系统用于生成计算机断层摄影图像。计算机断层摄影系统包括处理器，其被配置为访问在检测器位置处编码X射线投影的图像数据和多个X射线源束焦点位置，并且在位置的偏离方向上对准投影的像素值。处理器还被配置为基于对准的像素值和投影的总和来确定至少一个投影的校正因子，并且基于校正因子来校正至少一个投影的像素值。

2. 发明授权

US07929659B2 System and method for generating computed tomography images 有权
标题翻译：用于生成计算机断层摄影图像的系统和方法
公开(公告)号：US07929659B2
公开(公告)日：2011-04-19
申请号：US12179298
申请日：2008-07-24
申请人： Xiaoye Wu , Fang Frank Dong , James Walter Leblanc
发明人： Xiaoye Wu , Fang Frank Dong , James Walter Leblanc
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B6/4028 , A61B6/583 , Y10S378/901
摘要： A computed tomographic imaging system is provided for generating computed tomography images. The computed tomographic system includes a processor configured to access image data encoding X-ray projections at a detector position and a plurality of X-ray source beam focal spot positions and to align pixel values for the projections in a direction of deviation of the positions. The processor is also configured to determine a correction factor for at least one of the projections based upon the aligned pixel values and upon a sum of the projections and to correct the pixel values for the at least one of the projections based upon the correction factor.
摘要翻译：提供计算机断层摄影系统用于生成计算机断层摄影图像。计算机断层摄影系统包括处理器，其被配置为访问在检测器位置处编码X射线投影的图像数据和多个X射线源束焦点位置，并且在位置的偏离方向上对准投影的像素值。处理器还被配置为基于对准的像素值和投影的总和来确定至少一个投影的校正因子，并且基于校正因子来校正至少一个投影的像素值。

3. 发明申请

US20090161814A1 METHOD FOR CALIBRATING A DUAL -SPECTRAL COMPUTED TOMOGRAPHY (CT) SYSTEM 有权
标题翻译：用于校准双重计算机图像（CT）系统的方法
公开(公告)号：US20090161814A1
公开(公告)日：2009-06-25
申请号：US11959709
申请日：2007-12-19
申请人： Xiaoye Wu , James Walter Leblanc , Paavana Sainath
发明人： Xiaoye Wu , James Walter Leblanc , Paavana Sainath
IPC分类号： G12B13/00 , G06K9/00 , A61B6/03
CPC分类号： A61B6/583 , A61B6/032 , A61B6/482 , A61B6/505
摘要： A method for calibrating and reconstructing material density images in a dual-spectral computed tomography (CT) system 100 is disclosed. An X-ray source in the CT system 100 emits a first X-ray spectrum and a second X-ray spectrum towards an object. The method includes computing calibration coefficients by using projection data from the object for the two X-ray spectra and by linearizing at least two basis materials such as bone and water simultaneously. Further, basis materials decomposition coefficients for the at least two basis materials are computed by linearizing the basis materials individually. Correction values for the projection data and for the basis materials are then computed by using the basis materials decomposition coefficients and the calibration coefficients. The computed correction values are used in reconstructing material density images for the basis materials.
摘要翻译：公开了一种用于在双光谱计算机断层摄影（CT）系统100中校准和重建材料密度图像的方法。 CT系统100中的X射线源朝向物体发射第一X射线光谱和第二X射线光谱。该方法包括通过使用来自对象的两个X射线光谱的投影数据和同时线性化至少两种基础材料例如骨骼和水来计算校准系数。此外，通过将基础材料单独线性化来计算至少两种基础材料的基础材料分解系数。然后通过使用基础材料分解系数和校准系数来计算投影数据和基础材料的校正值。计算的校正值用于重建基础材料的材料密度图像。

4. 发明授权

US07492855B2 System and method for detecting an object 有权
标题翻译：用于检测物体的系统和方法
公开(公告)号：US07492855B2
公开(公告)日：2009-02-17
申请号：US10743195
申请日：2003-12-22
申请人： Forrest Frank Hopkins , Peter Michael Edic , Samit Kumar Basu , Bruno De Man , James Walter Leblanc , Xiaoye Wu , Deborah Joy Walter , William Robert Ross , Colin Richard Wilson , Ricardo Scott Avila , Robert August Kaucic, Jr.
发明人： Forrest Frank Hopkins , Peter Michael Edic , Samit Kumar Basu , Bruno De Man , James Walter Leblanc , Xiaoye Wu , Deborah Joy Walter , William Robert Ross , Colin Richard Wilson , Ricardo Scott Avila , Robert August Kaucic, Jr.
IPC分类号： G01N23/04
CPC分类号： G01V5/0016 , A61B6/4035 , A61B6/4241 , A61B6/482 , G01V5/0041 , G01V5/005 , G06F19/00
摘要： A system and method for ascertaining the identity of an object within an enclosed article. The system includes an acquisition subsystem utilizing a stationary radiation source and detector, a reconstruction subsystem, a computer-aided detection (CAD) subsystem, and a 2D/3D visualization subsystem. The detector may be an energy discriminating detector. The acquisition subsystem communicates view data to the reconstruction subsystem, which reconstructs it into image data and communicates it to the CAD subsystem. The CAD subsystem analyzes the image data to ascertain whether it contains any area of interest. Any such area of interest data is sent to the reconstruction subsystem for further reconstruction, using more rigorous algorithms and further analyzed by the CAD subsystem. Other information, such as risk variables or trace chemical detection information may be communicated to the CAD subsystem to be included in its analysis.
摘要翻译：用于确定封闭物品内物体的身份的系统和方法。该系统包括利用固定辐射源和检测器，重建子系统，计算机辅助检测（CAD）子系统和2D / 3D可视化子系统的采集子系统。检测器可以是能量识别检测器。采集子系统将视图数据传送到重建子系统，将其重建为图像数据并将其传送到CAD子系统。 CAD子系统分析图像数据，以确定它是否包含任何感兴趣的区域。任何这样的感兴趣的数据区域被发送到重建子系统以进一步重建，使用更严格的算法并由CAD子系统进一步分析。其他信息，例如风险变量或痕量化学检测信息可以传达给CAD子系统以包含在其分析中。

5. 发明授权

US08155263B2 Apparatus and method for voltage modulation in X-ray computed tomography 有权
标题翻译： X射线计算机断层扫描中电压调制的装置和方法
公开(公告)号：US08155263B2
公开(公告)日：2012-04-10
申请号：US12534087
申请日：2009-07-31
申请人： Xiaoye Wu , David Allen Langan , James Walter LeBlanc , Dan Xu
发明人： Xiaoye Wu , David Allen Langan , James Walter LeBlanc , Dan Xu
IPC分类号： H05G1/60
CPC分类号： A61B6/544 , A61B6/027 , A61B6/032 , A61B6/488
摘要： The present invention discloses a computed tomography imager comprising: an x-ray source disposed in a gantry; a detector assembly for receiving an x-ray emission from an x-ray source, the x-ray source and the detector assembly rotatable about an imaging target; an imager control system for selectively modulating a kVp operating value in the x-ray source during a scan slice in accordance with an x-ray modulation software program; and a computer for receiving data from the detector assembly, and for providing control signals to the imager control system by executing the x-ray modulation software program for at least a portion of the total possible rotational scanning range of the x-ray source.
摘要翻译：本发明公开了一种计算机断层成像仪，包括：设置在台架中的x射线源; 用于从X射线源接收x射线发射的检测器组件，所述x射线源和所述检测器组件围绕成像靶旋转; 成像器控制系统，用于根据x射线调制软件程序在扫描切片期间选择性地调制x射线源中的kVp操作值; 以及计算机，用于从检测器组件接收数据，并且通过对X射线源的总可能的旋转扫描范围的至少一部分执行x射线调制软件程序来向成像器控制系统提供控制信号。

6. 发明授权

US07801264B2 Method for calibrating a dual -spectral computed tomography (CT) system 有权
标题翻译：校准双光谱计算机断层摄影（CT）系统的方法
公开(公告)号：US07801264B2
公开(公告)日：2010-09-21
申请号：US11959709
申请日：2007-12-19
申请人： Xiaoye Wu , James Walter Leblanc , Paavana Sainath
发明人： Xiaoye Wu , James Walter Leblanc , Paavana Sainath
IPC分类号： A61B6/00
CPC分类号： A61B6/583 , A61B6/032 , A61B6/482 , A61B6/505
摘要： A method for calibrating and reconstructing material density images in a dual-spectral computed tomography (CT) system 100 is disclosed. An X-ray source in the CT system 100 emits a first X-ray spectrum and a second X-ray spectrum towards an object. The method includes computing calibration coefficients by using projection data from the object for the two X-ray spectra and by linearizing at least two basis materials such as bone and water simultaneously. Further, basis materials decomposition coefficients for the at least two basis materials are computed by linearizing the basis materials individually. Correction values for the projection data and for the basis materials are then computed by using the basis materials decomposition coefficients and the calibration coefficients. The computed correction values are used in reconstructing material density images for the basis materials.
摘要翻译：公开了一种用于在双光谱计算机断层摄影（CT）系统100中校准和重建材料密度图像的方法。 CT系统100中的X射线源朝向物体发射第一X射线光谱和第二X射线光谱。该方法包括通过使用来自对象的两个X射线光谱的投影数据和同时线性化至少两种基础材料例如骨骼和水来计算校准系数。此外，通过将基础材料单独线性化来计算至少两种基础材料的基础材料分解系数。然后通过使用基础材料分解系数和校准系数来计算投影数据和基础材料的校正值。计算的校正值用于重建基础材料的材料密度图像。

7. 发明授权

US07031426B2 Methods and system for detecting components of plaque 有权
标题翻译：检测斑块成分的方法和系统
公开(公告)号：US07031426B2
公开(公告)日：2006-04-18
申请号：US10625437
申请日：2003-07-23
申请人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
发明人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
IPC分类号： A61B6/03
CPC分类号： A61B5/02007 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/481 , A61B6/482 , A61B6/583 , A61B17/22 , A61B2090/374 , A61B2090/376
摘要： A method including detecting components of plaque using a multi-energy computed tomography (MECT) system is provided.
摘要翻译：提供了一种使用多能计算机断层摄影（MECT）系统检测斑块成分的方法。

8. 发明授权

US08055039B2 System and method to obtain noise mitigated monochromatic representation for varying energy level 有权
标题翻译：获得噪声减轻单色表示的系统和方法，以改变能级
公开(公告)号：US08055039B2
公开(公告)日：2011-11-08
申请号：US12035072
申请日：2008-02-21
申请人： Xiaoye Wu , David Allen Langan , James Walter LeBlanc
发明人： Xiaoye Wu , David Allen Langan , James Walter LeBlanc
IPC分类号： G06K9/00
CPC分类号： G06T5/002 , G06T2207/10081 , G06T2207/30004
摘要： In dual energy CT, through basis material decomposition (BMD), a pair of density images can be reconstructed. The noises in this image pair are negatively correlated due to the BMD process. A technique is presented for obtaining the monochromatic images at desired energy levels with reduced correlation noise. The technique includes obtaining a plurality of optimum attenuation coefficients for an energy level, selecting a desired energy level, obtaining a plurality of desired attenuation coefficients for the desired energy level, computing a scaling factor for a corresponding noise component based on the optimum attenuation coefficients and the desired attenuation coefficients, and generating a monochromatic image based upon the scaling factor.
摘要翻译：在双能量CT中，通过基础材料分解（BMD），可以重构一对密度图像。由于BMD过程，该图像对中的噪声是负相关的。提出了一种技术，用于以降低的相关噪声在期望的能级获得单色图像。该技术包括获得能量水平的多个最佳衰减系数，选择所需能级，获得所需能级的多个期望衰减系数，基于最佳衰减系数计算相应噪声分量的缩放因子，以及期望的衰减系数，以及基于缩放因子产生单色图像。

9. 发明申请

US20110026668A1 Apparatus and Method for Voltage Modulation in X-Ray Computed Tomography 有权
标题翻译： X射线计算机断层扫描中电压调制的装置和方法
公开(公告)号：US20110026668A1
公开(公告)日：2011-02-03
申请号：US12534087
申请日：2009-07-31
申请人： Xiaoye Wu , David Allen Langan , James Walter LeBlanc , Dan Xu
发明人： Xiaoye Wu , David Allen Langan , James Walter LeBlanc , Dan Xu
IPC分类号： H05G1/60
CPC分类号： A61B6/544 , A61B6/027 , A61B6/032 , A61B6/488
摘要： The present invention discloses a computed tomography imager comprising: an x-ray source disposed in a gantry; a detector assembly for receiving an x-ray emission from an x-ray source, the x-ray source and the detector assembly rotatable about an imaging target; an imager control system for selectively modulating a kVp operating value in the x-ray source during a scan slice in accordance with an x-ray modulation software program; and a computer for receiving data from the detector assembly, and for providing control signals to the imager control system by executing the x-ray modulation software program for at least a portion of the total possible rotational scanning range of the x-ray source.
摘要翻译：本发明公开了一种计算机断层成像仪，包括：设置在台架中的x射线源; 用于从X射线源接收x射线发射的检测器组件，所述x射线源和所述检测器组件围绕成像靶旋转; 成像器控制系统，用于根据x射线调制软件程序在扫描切片期间选择性地调制x射线源中的kVp工作值; 以及计算机，用于从检测器组件接收数据，并且通过对X射线源的总可能的旋转扫描范围的至少一部分执行x射线调制软件程序来向成像器控制系统提供控制信号。

10. 发明授权

US07826587B1 System and method of fast kVp switching for dual energy CT 有权
标题翻译：双能CT快速kVp开关系统及方法
公开(公告)号：US07826587B1
公开(公告)日：2010-11-02
申请号：US12558248
申请日：2009-09-11
申请人： David Allen Langan , John Eric Tkaczyk , James Walter LeBlanc , Colin R. Wilson , Xiaoye Wu , Dan Xu , Thomas Matthew Benson , Jed Douglas Pack
发明人： David Allen Langan , John Eric Tkaczyk , James Walter LeBlanc , Colin R. Wilson , Xiaoye Wu , Dan Xu , Thomas Matthew Benson , Jed Douglas Pack
IPC分类号： H05G1/60
CPC分类号： A61B6/405 , A61B6/032 , A61B6/482
摘要： A CT system includes a gantry, an x-ray source, a generator configured to energize the x-ray source to a first kVp and to a second kVp, a detector, and a controller. The controller is configured energize the x-ray source to the first kVp for a first time period, subsequently energize the x-ray source to the second kVp for a second time period, integrate data for a first integration period that includes a portion of a steady-state period of the x-ray source at the first kVp, integrate data for a second integration period that includes a portion of a steady-state period of the x-ray source at the second kVp, compare a signal-to-noise ratio (SNR) during the first integration period (SNRH) and the second integration period (SNRL), adjust an operating parameter of the CT system to optimize an SNRH with SNRL, and generate an image using the integrated data.
摘要翻译： CT系统包括台架，x射线源，被配置为将x射线源激发到第一kVp的发生器和到第二kVp的检测器和控制器的发生器。控制器被配置为在第一时间段内将x射线源激励到第一kVp，随后将x射线源激励到第二kVp第二时间段，将包含第一时间段的第一积分周期的数据整合在第一kVp处的x射线源的稳态周期，将包括X射线源的稳态周期的一部分的第二积分周期的数据集成在第二kVp处，比较信号与噪声在第一积分周期（SNRH）和第二积分周期（SNRL）期间的比率（SNR），调整CT系统的运行参数以利用SNRL优化SNRH，并使用积分数据生成图像。

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