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1. 发明授权

US07031426B2 Methods and system for detecting components of plaque 有权
标题翻译：检测斑块成分的方法和系统
公开(公告)号：US07031426B2
公开(公告)日：2006-04-18
申请号：US10625437
申请日：2003-07-23
申请人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
发明人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
IPC分类号： A61B6/03
CPC分类号： A61B5/02007 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/481 , A61B6/482 , A61B6/583 , A61B17/22 , A61B2090/374 , A61B2090/376
摘要： A method including detecting components of plaque using a multi-energy computed tomography (MECT) system is provided.
摘要翻译：提供了一种使用多能计算机断层摄影（MECT）系统检测斑块成分的方法。

2. 发明授权

US07627078B2 Methods and apparatus for detecting structural, perfusion, and functional abnormalities 有权
标题翻译：用于检测结构，灌注和功能异常的方法和装置
公开(公告)号：US07627078B2
公开(公告)日：2009-12-01
申请号：US10065689
申请日：2002-11-08
申请人： Jiang Hsieh , Ricardo Scott Avila , Maria Iatrou , Shankara B. Reddy , Peter Michael Edic
发明人： Jiang Hsieh , Ricardo Scott Avila , Maria Iatrou , Shankara B. Reddy , Peter Michael Edic
IPC分类号： G01N23/00
CPC分类号： A61B6/507 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/481 , A61B6/482 , G06F19/00 , Y10S378/901
摘要： A Multi-Energy Computed Tomography (MECT) System is provided. The system includes a radiation source rotatable about a patient, a radiation detector, and a computer coupled to the radiation source and the radiation detector wherein the computer is configured to receive data regarding a first energy spectrum of a scan of a head of the patient, receive data regarding a second energy spectrum of a scan of the head, and generate an image using the received data.
摘要翻译：提供多能计算层析成像（MECT）系统。该系统包括可围绕患者旋转的辐射源，辐射检测器和耦合到辐射源和辐射检测器的计算机，其中计算机被配置为接收关于患者头部的扫描的第一能量谱的数据，接收关于头部扫描的第二能量谱的数据，并使用接收的数据生成图像。

3. 发明授权

US07382852B2 Method and apparatus for correcting motion in image reconstruction 有权
标题翻译：用于校正图像重建中运动的方法和装置
公开(公告)号：US07382852B2
公开(公告)日：2008-06-03
申请号：US11804861
申请日：2007-05-21
申请人： Peter Michael Edic , Maria Iatrou , Erdogan Cesmeli , Bruno De Man , Samit Basu
发明人： Peter Michael Edic , Maria Iatrou , Erdogan Cesmeli , Bruno De Man , Samit Basu
IPC分类号： G01N23/00
CPC分类号： A61B6/541 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/482 , A61B6/503 , A61B6/563 , G01N23/046 , G01N2223/419 , G01N2223/612 , G06T5/003 , G06T5/50 , G06T7/246 , G06T11/005 , G06T2207/10081 , G06T2207/30004 , G06T2211/408 , G06T2211/412 , Y10S378/901
摘要： One or more techniques are provided for adapting a reconstruction process to account for the motion of an imaged object or organ, such as the heart. In particular, projection data of the moving object or organ is acquired using a slowly rotating CT gantry. Motion data may be determined from the projection data or from images reconstructed from the projection data. The motion data may be used to reconstruct motion-corrected images from the projection data. The motion-corrected images may be associated to form motion-corrected volume renderings.
摘要翻译：提供一种或多种技术用于调整重建过程以解决成像对象或器官（例如心脏）的运动。特别地，使用缓慢旋转的CT台架来获取移动物体或器官的投影数据。可以从投影数据或从投影数据重建的图像确定运动数据。运动数据可用于从投影数据重建运动校正图像。可以将运动校正的图像相关联以形成运动校正的体积渲染。

4. 发明授权

US06765983B2 Method and apparatus for imaging a region of dynamic tissue 失效
标题翻译：用于成像动态组织区域的方法和装置
公开(公告)号：US06765983B2
公开(公告)日：2004-07-20
申请号：US10318909
申请日：2002-12-13
申请人： Weizhong Yan , Peter Michael Edic , Maria Iatrou , Kai Frank Goebel , Erdogan Cesmeli
发明人： Weizhong Yan , Peter Michael Edic , Maria Iatrou , Kai Frank Goebel , Erdogan Cesmeli
IPC分类号： A61B603
CPC分类号： A61B6/469 , A61B6/032 , A61B6/5264 , A61B6/541 , A61B6/563 , Y10S378/901
摘要： A technique is provided for reducing motion-related artifacts present in CT images attributable to the dynamic nature of the imaged tissue or the time-varying concentration of a contrast agent. A region of interest that encompasses a structure of diagnostic significance is selected. For projections acquired by the various rows of detectors in a multi-slice CT imaging system, the portions of the projections attributable to the projection of the region of interest are averaged for each view angle. The projections containing these averaged values are then combined with the projections which do not encompass the region of interest. The combined projection set may be reconstructed to form a CT image of the dynamic tissue. In addition, a smoothing step may be performed to interpolate projection values around the region of interest to smooth the visual transition to the unaveraged portions of the image.
摘要翻译：提供了一种技术，用于减少归因于成像组织的动态特性或造影剂的时变浓度的CT图像中存在的运动相关假象。选择包含诊断意义的结构的感兴趣区域。对于由多层CT成像系统中的各行检测器获取的投影，可以对于每个视角对平均感兴趣区域的投影的投影的部分进行平均。然后将包含这些平均值的投影与不包含感兴趣区域的投影组合。可以重组组合投影集以形成动态组织的CT图像。此外，可以执行平滑步骤来内插围绕感兴趣区域的投影值，以平滑对图像的未平面部分的视觉转换。

5. 发明申请

US20110142313A1 METHOD FOR COMPUTED TOMOGRAPHY MOTION ESTIMATION AND COMPENSATION 有权
标题翻译：计算机运动估计和补偿方法
公开(公告)号：US20110142313A1
公开(公告)日：2011-06-16
申请号：US12638693
申请日：2009-12-15
申请人： Jed Douglas Pack , Peter Michael Edic , Bernhard Erich Hermann Claus , Maria Iatrou , James Vradenburg Miller
发明人： Jed Douglas Pack , Peter Michael Edic , Bernhard Erich Hermann Claus , Maria Iatrou , James Vradenburg Miller
IPC分类号： G06K9/36 , H05G1/60
CPC分类号： G06T11/005 , G06T7/11 , G06T7/174 , G06T7/246 , G06T2207/10081 , G06T2207/30048 , G06T2207/30101 , G06T2207/30172 , G06T2211/412
摘要： A method and system for motion estimation and compensation are disclosed. Initially, a set of one or more initial images is reconstructed using acquired imaging data. Further, one or more regions of interest are identified in this set of reconstructed initial images. At least a set of filters is applied to the identified regions of interest to generate a sequence of filtered images. Particularly, each of the filtered images in the generated sequence of filtered images includes data acquired near a different reference point. Subsequently, a motion path corresponding to each region of interest is determined based on one or more correspondences in the sequence of filtered images.
摘要翻译：公开了一种用于运动估计和补偿的方法和系统。最初，使用获取的成像数据重建一组一个或多个初始图像。此外，在该组重建的初始图像中识别一个或多个感兴趣区域。至少一组滤波器被应用于所识别的感兴趣区域以产生滤波图像序列。特别地，所生成的滤波图像序列中的每个滤波图像包括在不同参考点附近获取的数据。随后，基于滤波图像的序列中的一个或多个对应来确定对应于每个感兴趣区域的运动路径。

6. 发明授权

US07221728B2 Method and apparatus for correcting motion in image reconstruction 有权
标题翻译：用于校正图像重建中运动的方法和装置
公开(公告)号：US07221728B2
公开(公告)日：2007-05-22
申请号：US10625361
申请日：2003-07-23
申请人： Peter Michael Edic , Maria Iatrou , Erdogan Cesmeli , Bruno De Man , Samit Basu
发明人： Peter Michael Edic , Maria Iatrou , Erdogan Cesmeli , Bruno De Man , Samit Basu
IPC分类号： G01N23/04
CPC分类号： A61B6/541 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/482 , A61B6/503 , A61B6/563 , G01N23/046 , G01N2223/419 , G01N2223/612 , G06T5/003 , G06T5/50 , G06T7/246 , G06T11/005 , G06T2207/10081 , G06T2207/30004 , G06T2211/408 , G06T2211/412 , Y10S378/901
摘要： One or more techniques are provided for adapting a reconstruction process to account for the motion of an imaged object or organ, such as the heart. In particular, projection data of the moving object or organ is acquired using a slowly rotating CT gantry. Motion data may be determined from the projection data or from images reconstructed from the projection data. The motion data may be used to reconstruct motion-corrected images from the projection data. The motion-corrected images may be associated to form motion-corrected volume renderings.
摘要翻译：提供一种或多种技术用于调整重建过程以解决成像对象或器官（例如心脏）的运动。特别地，使用缓慢旋转的CT台架来获取移动物体或器官的投影数据。可以从投影数据或从投影数据重建的图像确定运动数据。运动数据可用于从投影数据重建运动校正图像。可以将运动校正的图像相关联以形成运动校正的体积渲染。

7. 发明授权

US07054475B2 Apparatus and method for volumetric reconstruction of a cyclically moving object 有权
公开(公告)号：US07054475B2
公开(公告)日：2006-05-30
申请号：US10033952
申请日：2001-12-28
申请人： Peter Michael Edic , Maria Iatrou
发明人： Peter Michael Edic , Maria Iatrou
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , G06T2211/412
摘要： A method for volumetric reconstruction of a cyclically moving object using a computed tomography (CT) system includes scanning a cyclically moving object with a CT imaging system including at least one of an area detector and a linear detector to encompass the desired field of view and a rotating gantry to measure projection data during a plurality of cycles of the cyclically moving object. The method also includes dividing a period of the cyclically moving object into a discrete number of phases, identifying an initial set of projection data at a desired phase of a first cycle at a first angle, identifying at least one subsequent set of projection data at the same desired phase of a subsequent cycle at an angle that is different from the first angle, and combining the initial set of projection data with each subsequent set of identified projection data and using a reconstruction algorithm to generate a three-dimensional image. The method further includes repeating the steps of identifying an initial set of projection data at a desired phase of a first cycle at a first angle, identifying at least one subsequent set of projection data at the same desired phase of a subsequent cycle at an angle that is different from the first angle, and combining the initial set of projection data with each subsequent set of identified projection data and using a reconstruction algorithm to generate a collection of three-dimensional images for the desired phases; and temporally filtering the collection of three-dimensional images on a pixel by pixel basis.

8. 发明授权

US06956926B2 Method and apparatus for selecting a reconstruction projection set 失效
标题翻译：用于选择重建投影集的方法和装置
公开(公告)号：US06956926B2
公开(公告)日：2005-10-18
申请号：US10335826
申请日：2002-12-31
申请人： Erdogan Cesmeli , Peter Michael Edic , Maria Iatrou
发明人： Erdogan Cesmeli , Peter Michael Edic , Maria Iatrou
IPC分类号： G06T11/00 , A61B6/00
CPC分类号： G06T11/005 , G06T2211/412
摘要： A technique is provided for improving consistency between slabs in a reconstructed CT image. Candidate sectors associated with an image slab are determined. If the sectors contain sufficient information to reconstruct the image slab, the sector which minimizes inconsistency with projection data for adjacent image slabs is selected for reconstruction. If the sectors do not contain sufficient information to reconstruct the slab, sectors are merged together until a merge group contains sufficient information. The merge group which minimizes inconsistency with projection data for adjacent image slabs is selected for image reconstruction. The selected sectors or merge groups are then reconstructed with the resulting image slabs comprising a reconstructed image with improved consistency between image slabs.
摘要翻译：提供了一种用于改善重建CT图像中的平板之间的一致性的技术。确定与图像板相关联的候选扇区。如果扇区含有足够的信息来重建图像板，则选择最小化与相邻图像板的投影数据不一致的扇区用于重建。如果扇区不包含足够的信息来重建slab，则扇区合并在一起，直到合并组包含足够的信息。选择最小化与相邻图像板的投影数据不一致的合并组用于图像重建。然后使用包括具有改进的图像板之间的一致性的重建图像的所得到的图像板来重建所选择的扇区或合并组。

9. 发明授权

US08224056B2 Method for computed tomography motion estimation and compensation 有权
标题翻译：计算机断层扫描运动估计和补偿方法
公开(公告)号：US08224056B2
公开(公告)日：2012-07-17
申请号：US12638693
申请日：2009-12-15
申请人： Jed Douglas Pack , Peter Michael Edic , Bernhard Erich Hermann Claus , Maria Iatrou , James Vradenburg Miller
发明人： Jed Douglas Pack , Peter Michael Edic , Bernhard Erich Hermann Claus , Maria Iatrou , James Vradenburg Miller
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , G06T7/11 , G06T7/174 , G06T7/246 , G06T2207/10081 , G06T2207/30048 , G06T2207/30101 , G06T2207/30172 , G06T2211/412
摘要： A method and system for motion estimation and compensation are disclosed. Initially, a set of one or more initial images is reconstructed using acquired imaging data. Further, one or more regions of interest are identified in this set of reconstructed initial images. At least a set of filters is applied to the identified regions of interest to generate a sequence of filtered images. Particularly, each of the filtered images in the generated sequence of filtered images includes data acquired near a different reference point. Subsequently, a motion path corresponding to each region of interest is determined based on one or more correspondences in the sequence of filtered images.
摘要翻译：公开了一种用于运动估计和补偿的方法和系统。最初，使用获取的成像数据重建一组一个或多个初始图像。此外，在该组重建的初始图像中识别一个或多个感兴趣区域。至少一组滤波器被应用于所识别的感兴趣区域以产生滤波图像序列。特别地，所生成的滤波图像序列中的每个滤波图像包括在不同参考点附近获取的数据。随后，基于滤波图像的序列中的一个或多个对应来确定对应于每个感兴趣区域的运动路径。

10. 发明授权

US07477771B2 Method and system for extracting information about the cardiac cycle from CT projection data 有权
标题翻译：从CT投影数据提取心动周期信息的方法和系统
公开(公告)号：US07477771B2
公开(公告)日：2009-01-13
申请号：US11003114
申请日：2004-12-03
申请人： Maria Iatrou , Jong Chul Ye , Samit Kumar Basu , Bruno Kristiaan Bernard De Man , Peter Michael Edic
发明人： Maria Iatrou , Jong Chul Ye , Samit Kumar Basu , Bruno Kristiaan Bernard De Man , Peter Michael Edic
IPC分类号： G06K9/00 , A61B6/00 , A61B5/05
CPC分类号： A61B6/032 , A61B6/027 , A61B6/503 , A61B6/5217 , A61B6/541 , G06T11/005 , G06T2211/412
摘要： A method for extracting information of a cardiac cycle from projection data is presented. The method provides for acquiring one or more sets of computed tomography (CT) projection data. Further, the method includes analyzing the one or sets of CT projection data to obtain a center of cardiac mass. Also, the method provides for estimating raw motion data representative of the motion of the center of cardiac mass from the one or more sets of CT projection data. In addition, the method includes processing the center of mass through time to extract a motion signal from the raw projection data. Also, the method provides for extracting the periodicity information from the motion signal.
摘要翻译：提出了一种从投影数据提取心动周期信息的方法。该方法提供一组或多组计算机断层摄影（CT）投影数据。此外，该方法包括分析一组或多组CT投影数据以获得心脏质量的中心。此外，该方法还提供了用于从一个或多个CT投影数据集合估计表示心脏质心的运动的原始运动数据。此外，该方法包括通过时间处理质心以从原始投影数据中提取运动信号。此外，该方法提供从运动信号中提取周期性信息。

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