专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5499967A Transdermal drug delivery device with waveshape generator 失效
标题翻译：具有波形发生器的透皮药物输送装置
公开(公告)号：US5499967A
公开(公告)日：1996-03-19
申请号：US181078
申请日：1994-01-13
申请人： Eric Teillaud , Bruno Bevan , Claude Mikler , Paul Reilly , Philippe Millot
发明人： Eric Teillaud , Bruno Bevan , Claude Mikler , Paul Reilly , Philippe Millot
IPC分类号： A61N1/32 , A61N1/37 , G05F1/46 , H02M3/157 , A61N1/30
CPC分类号： G05F1/468 , A61N1/325 , A61N1/37 , H02M3/157
摘要： The device comprises a switched-mode power supply (1) equipped with an electronic switching member (T.sub.1), the closing of which controls the power supply to an inductor (L.sub.1) which discharges, when the member reopens, into a capacitor (C.sub.1) at the terminals of which the output voltage of the device appears, characterized in that it comprises (a) storage means for recording a sequence of image numbers of successive segments of the predetermined waveform, (b) a clocked digital counter (2) and (c) means (3) for successively loading this counter (2) with each of the numbers of this sequence considered as a bound of the count performed by the counter (2), the latter cyclically controlling the closing of the switching member (T.sub.1) for a predetermined time interval, each time the count performed reaches the limit thus fixed.
摘要翻译：该装置包括配备有电子开关元件（T1）的开关电源（1），其关闭控制向电感器（L1）的电源，当电容器重新开启时，电感器（L1）放电到电容器（C1）中，在其端子处出现输出电压，其特征在于它包括：（a）用于记录预定波形的连续段的图像序列序列的存储装置，（b）时钟数字计数器（2）和（ c）用于连续加载该计数器（2）的装置（3），其中该序列的每个编号被认为是由计数器（2）执行的计数的边界，后者循环地控制切换构件（T1）的关闭，每次执行的计数达到如此固定的极限时，预定的时间间隔。

2. 发明授权

US5426387A Device for generating an electrical voltage of predetermined waveform, iontophoresis apparatus for transdermally administering medicinal products and electrical stimulation apparatus, which apparatuses are equipped with such a device 失效
标题翻译：用于产生预定波形的电压的装置，用于经皮给药药物的离子电渗疗法和电刺激装置，所述装置装备有这种装置
公开(公告)号：US5426387A
公开(公告)日：1995-06-20
申请号：US16269
申请日：1993-02-11
申请人： Eric Teillaud , Bruno Bevan , Claude Mikler , Paul Reilly
发明人： Eric Teillaud , Bruno Bevan , Claude Mikler , Paul Reilly
IPC分类号： A61N1/30 , A61N1/32 , A61N1/37 , G05F1/46 , H02M3/155 , H02M3/157 , H03K4/92 , H03K4/02
CPC分类号： G05F1/468 , A61N1/325 , A61N1/37 , H02M3/157
摘要： The device comprises a switched-mode power supply (1) equipped with an electronic switching member (T.sub.1), the closing of which controls the power supply to an inductor (L.sub.1) which discharges, when the member reopens, into a capacitor (C.sub.1) at the terminals of which the output voltage of the device appears, characterized in that it comprises (a) storage means for recording a sequence of image numbers of successive segments of the predetermined waveform, (b) a clocked digital counter (2) and (c) means (3) for successively loading this counter (2) with each of the numbers of this sequence considered as a bound of the count performed by the counter (2), the latter cyclically controlling the closing of the switching member (T.sub.1) for a predetermined time interval, each time the count performed reaches the limit thus fixed.
摘要翻译：该装置包括配备有电子开关元件（T1）的开关电源（1），其关闭控制向电感器（L1）的电源，当电容器重新开启时，电感器（L1）放电到电容器（C1）中，在其端子处出现输出电压，其特征在于它包括：（a）用于记录预定波形的连续段的图像序列序列的存储装置，（b）时钟数字计数器（2）和（ c）用于连续加载该计数器（2）的装置（3），其中该序列的每个编号被认为是由计数器（2）执行的计数的边界，后者循环地控制切换构件（T1）的关闭，每次执行的计数达到如此固定的极限时，预定的时间间隔。

3. 发明授权

US06247485B1 Miniature valve for filling the reservoir of an apparatus for the transdermal administration of medicine 有权
标题翻译：用于填充用于透皮给药的装置的储存器的微型阀
公开(公告)号：US06247485B1
公开(公告)日：2001-06-19
申请号：US09285000
申请日：1999-07-20
申请人： Carole Rossi , Philippe Millot , Daniel Esteve , Claude Mikler , Eric Teillaud
发明人： Carole Rossi , Philippe Millot , Daniel Esteve , Claude Mikler , Eric Teillaud
IPC分类号： A61M500
CPC分类号： F16K99/0001 , A61M37/00 , A61M2205/0244 , F15C5/00 , F16K99/003 , F16K99/0067 , F16K2099/0074 , F16K2099/008 , F16K2099/0086 , Y10T137/1647
摘要： A miniature valve for filling the reservoir of an apparatus for the transdermal administration of a medicine including a) a substrate, b) a fuel charge arranged on the substrate opposite the passage to be opened through it, and c) an electric resistor placed in contact with the fuel charge so that the supply of this resistor with a predetermined electric energy ensures the combustion of the charge and the opening of the passage by local rupture of the substrate under the pressure of the fuel gases of the charge. The device is useful for filling a medicine reservoir for the transdermal administration medicine aided by inophoresis.
摘要翻译：一种用于填充用于经皮给药的药物的储存器的微型阀，包括：a）基底; b）布置在所述基底上的燃料电荷，所述燃料电荷与所述待通过的通道相对; c）电阻器，燃料电荷使得具有预定电能的该电阻器的供应通过在电荷的燃料气体的压力下的基板的局部破裂来确保电荷的燃烧和通道的打开。该装置可用于填充用于透皮给药药物的药物储存器，辅助通过吸气。

4. 发明授权

US5983132A Ionophoretic device for transdermal administration of medicaments, and disposable assembly forming part of such device 失效
标题翻译：用于透皮给药的离子电泳装置，以及形成这种装置的一部分的一次性组装
公开(公告)号：US5983132A
公开(公告)日：1999-11-09
申请号：US836308
申请日：1997-05-12
申请人： Philippe Millot , Eric Teillaud , Michel Lamoise
发明人： Philippe Millot , Eric Teillaud , Michel Lamoise
IPC分类号： A61N1/30 , A61N1/00
CPC分类号： A61N1/044 , A61N1/303 , A61N1/0444
摘要： The device comprises a reservoir (3) containing an active principle in ionized form, first (1) and second (2) electrodes in contact with a face of the reservoir (3) and the skin (6) of the patient, respectively, the other face of the reservoir being applied to the skin (6) of the patient and means (5) for circulating selectively an electric current between said electrodes in order to help the passage of a flow of active principle under the patient's skin. The device further comprises a) a control grid (11) arranged on the face of the reservoir (3) which is intended to be applied to the skin (6) of the patient and b) control means (10), (9), (13) for cutting off the assistance current during a predetermined period of time and to circulate a reverse current between the grid (11) and the first electrode (1) which is intended to cancel substantially the passive flow of ions of the active principle which would otherwise pass under the patient's skin.
摘要翻译： PCT No.PCT / FR95 / 01509 Sec。 371日期：1997年5月12日 102（e）日期1997年5月12日PCT提交1995年11月16日PCT公布。 WO96 / 14896 PCT公开号日期1996年5月23日该装置包括容纳离子化形式的活性成分的储存器（3），与储存器（3）的表面和患者皮肤（6）接触的第一（1）和第二（2）电极分别将储存器的另一面施加到患者的皮肤（6），以及用于选择性地在所述电极之间循环电流的装置（5），以帮助活动原理流通过患者皮肤。该装置还包括：a）设置在储存器（3）的面上的控制栅格（11），该控制栅格旨在施加到患者的皮肤（6），以及b）控制装置（10），（9），（13），用于在预定时间段内切断辅助电流，并且使网格（11）和第一电极（1）之间的反向电流循环，该逆电流旨在基本上抵消有源原理的被动流离子否则会经过病人的皮肤。

5. 发明授权

US4837025A Self-adhesive device for the percutaneous administration of an active ingredient 失效
标题翻译：用于经皮给药活性成分的自粘装置
公开(公告)号：US4837025A
公开(公告)日：1989-06-06
申请号：US247852
申请日：1988-09-22
申请人： Alain Guillemet , Eric Teillaud , Philippe Reginault , Bruno Bevan
发明人： Alain Guillemet , Eric Teillaud , Philippe Reginault , Bruno Bevan
IPC分类号： A61K9/00 , A61K9/70 , A61K47/00
CPC分类号： A61K9/0014 , A61K9/7053
摘要： The present invention relates to a novel self-adhesive matrix for the percutaneous administration of a pharmaceutical active ingredient. This matrix comprises a combination of the following:(a) 30 to 50 parts by weight of an ethylene/vinyl acetate copolymer material,(b) 20 to 45 parts by weight of a higher aliphatic monoalcohol compound,(c) 5 to 20 parts by weight of a cellulose derivative material,(d) 1 to 20 parts by weight of an ester compound of a polyhydric alcohol with a fatty aliphatic acid, and(e) 0.1 to 20 parts by weight of an active ingredient which can be administered percutaneously.
摘要翻译：本发明涉及用于经皮给药药用活性成分的新型自粘基质。该基质包括以下组合：（a）30至50重量份的乙烯/乙酸乙烯酯共聚物材料，（b）20至45重量份的高级脂族一元醇化合物，（c）5至20重量份的纤维素衍生物，（d）1〜20重量份的多元醇与脂肪族脂肪酸的酯化合物，和（e）0.1〜20重量份可以经皮给药的活性成分。

6. 发明授权

US6013276A Transdermal matrix system 失效
标题翻译：透皮基质系统
公开(公告)号：US6013276A
公开(公告)日：2000-01-11
申请号：US43760
申请日：1998-03-26
申请人： Marie-Christine Math , Eric Teillaud , Bruno Bevan
发明人： Marie-Christine Math , Eric Teillaud , Bruno Bevan
IPC分类号： A61K9/70 , A61K38/22 , A61F13/02
CPC分类号： A61K9/7053
摘要： A novel transdermal matrix system for the percutaneous delivery of a hormone, including a carrier and an adhesive matrix, is disclosed. The matrix includes (a) 39-61 parts by weight of an ethylene/vinyl acetate copolymer, (b) 12-17 parts by weight of 2-octyldodecyl myristate, (c) 5-17 parts by weight of diethyl phthalate, (d) 10-16 parts by weight of a compound selected from N-alkyl-2-pyrrolidones, wherein the alkyl group is a C.sub.4-15 group, and (e) 1-12 parts by weight of at least one hormone selected from the group consisting of oestrogenic and progestogenic components. A method for preparing said transdermal matrix system and the therapeutical use of said system are also disclosed.
摘要翻译： PCT No.PCT / FR96 / 01494 Sec。 371日期：1998年3月26日 102（e）1998年3月26日PCT PCT 1996年9月25日PCT公布。公开号WO97 / 11687 日本1997年4月3日公开了一种用于经皮递送激素的新型透皮基质系统，包括载体和粘合剂基质。该基质包括（a）39-61重量份的乙烯/乙酸乙烯酯共聚物，（b）12-17重量份的肉豆蔻酸2-辛基十二烷基酯，（c）5-17重量份邻苯二甲酸二乙酯，（d ）10-16重量份选自N-烷基-2-吡咯烷酮的化合物，其中烷基是C4-15基团，和（e）1-12重量份的至少一种选自以下的激素由雌激素和孕激素组成。还公开了制备所述透皮基质体系的方法和所述系统的治疗用途。

7. 发明授权

US4895726A Novel dosage form of fenofibrate 失效
标题翻译：非诺贝特的新型剂型
公开(公告)号：US4895726A
公开(公告)日：1990-01-23
申请号：US299073
申请日：1989-01-19
申请人： Bernard Curtet , Eric Teillaud , Philippe Reginault
发明人： Bernard Curtet , Eric Teillaud , Philippe Reginault
IPC分类号： A61K9/14 , A61K9/48 , A61K9/64 , A61K31/215 , A61K31/22 , A61K45/08 , A61P3/06
CPC分类号： A61K9/4866 , A61K31/215 , A61K9/145 , A61K9/4858
摘要： The present invention relates to a novel dosage form of fenofibrate containing fenofibrate and a solid surfactant which have been co-micronized.It also relates to the method for the preparation of this dosage form and its use for improving the bioavailabity in vivo.
摘要翻译：本发明涉及已被共微粉化的含有非诺贝特和固体表面活性剂的非诺贝特的新型剂型。它还涉及制备该剂型的方法及其用于改善体内生物利用度的用途。

8. 发明授权

US5605702A Eva-based transdermal matrix system for the administration of an estrogen and/or a progestogen 失效
标题翻译：用于施用雌激素和/或孕激素的基于Eva的透皮基质系统
公开(公告)号：US5605702A
公开(公告)日：1997-02-25
申请号：US413208
申请日：1995-03-28
申请人： Eric Teillaud , Antoine Sawaya , Marie-Christine Math
发明人： Eric Teillaud , Antoine Sawaya , Marie-Christine Math
IPC分类号： A61F13/02 , A61K9/70 , A61K31/56 , A61K31/565 , A61K31/57 , A61K47/16 , A61K47/32 , A61K47/38 , A61P5/00 , A61F13/00
CPC分类号： A61K9/7053 , Y10S514/946
摘要： The present invention relates to a new self-adhesive transdermal matrix system for the administration of a hormone by percutaneous route, said system which comprises a support and self-adhesive matrix, having a matrix comprising:(a) 40 to 60 parts by weight of an ethylene/vinyl acetate copolymer,(b) 5 to 20 parts by weight of a cellulosic material,(c) 35 to 55 parts by weight of at least one compound selected from the group consisting of: crotamiton, N-substituted 2-pyrrolidones of the formula I, ##STR1## in which the R group represents a (C.sub.1 -C.sub.15)-alkyl, cyclohexyl or 2-hydroxyethyl group, and higher C.sub.12 -C.sub.20 aliphatic alcohols, and(d) 0,01 to 7 parts by weight of a hormone selected from the group consisting of estrogen components, progestogen components and mixtures thereof.It also relates to a method for preparing this transdermal matrix system.
摘要翻译：本发明涉及一种用于通过经皮途径施用激素的新型自粘性透皮基质体系，所述系统包括支持体和自粘性基质，所述基质包含：（a）40至60重量份的乙烯/乙酸乙烯酯共聚物，（b）5至20重量份的纤维素材料，（c）35至55重量份的至少一种选自以下的化合物：克罗他米通，N-取代的2-吡咯烷酮其中R基团表示（C1-C15） - 烷基，环己基或2-羟基乙基的式I，其中更高级的C 12 -C 20脂族醇，和（d）0.01至7 重量份的选自雌激素成分，孕激素成分及其混合物的激素。它还涉及一种制备该透皮基质体系的方法。

9. 发明授权

US4842864A Self-adhesive device for the percutaneous administration of an active ingredient 失效
标题翻译：用于经皮给药活性成分的自粘装置
公开(公告)号：US4842864A
公开(公告)日：1989-06-27
申请号：US174414
申请日：1988-03-25
申请人： Alain Guillemet , Eric Teillaud , Philippe Reginault
发明人： Alain Guillemet , Eric Teillaud , Philippe Reginault
IPC分类号： A61K9/70 , A61K47/00
CPC分类号： A61K9/7053
摘要： The present invention relates to a novel self-adhesive matrix for the percutaneous administration of an active ingredient. This matrix comprises a combination of the following:(a) 40 to 60 parts by weight of an ethylene/vinyl acetate copolymer material,(b) 40 to 60 parts by weight of a higher aliphatic monoalcohol compound,(c) 1 to 20 parts by weight of a cellulose derivative material,(d) 0.1 to 8 parts by weight of a polyhydric alcohol compound, and(e) 0.01 to 10 parts by weight of an active ingredient which can be administered percutaneously,the weight ratio a+c/b+d being between 0.7 and 1.3.
摘要翻译：本发明涉及一种用于经皮给药活性成分的新型自粘性基质。该基质包括以下组合：（a）40至60重量份的乙烯/乙酸乙烯酯共聚物材料，（b）40至60重量份的高级脂族一元醇化合物，（c）1至20重量份的纤维素衍生物，（d）0.1〜8重量份的多元醇化合物，（e）0.01〜10重量份可经皮给药的活性成分，重量比a + c / b + d在0.7和1.3之间。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式