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    • 9. 发明申请
    • EPOXY RESIN COMPOSITIONS AND PROCESS FOR PREPARING THEM
    • 环氧树脂组合物及其制备方法
    • US20100105856A1
    • 2010-04-29
    • US12518175
    • 2007-11-30
    • Michael HenningsenLars Wittenbecher
    • Michael HenningsenLars Wittenbecher
    • C08G59/02
    • C07D301/28C07D303/28C08G59/24
    • The preparation of epoxy resin compositions which comprise glycidyl ethers comprising cyclohexyl groups and have a low oligomer content is carried out by distillation of compositions which are obtainable by ring hydrogenation of compounds of the general formula (I) where -X- is —CR2—, —CO—, —O, —S—, —SO2—, the radicals R are each, independently of one another, H, C1-6-alkyl, C3-6-cycloalkyl, in which one or more H atoms can be replaced by halogen, the radicals R′ are each, independently of one another, C1-4-alkyl, halogen, the indices n are each, independently of one another, 0, 1, 2 or 3, and subsequent reaction of the hydroxyl groups with epichlorohydrin, in thin film evaporators or short path evaporators at a temperature in the range from 150 to 270° C. and a pressure in the range from 0.001 to 1 mbar.
    • 包含环己基并且具有低低聚物含量的缩水甘油醚的环氧树脂组合物的制备通过蒸馏可通过环化氢化通式(I)的化合物获得的组合物进行,其中-X-为-CR 2 - -CO - , - O - , - S - , - SO 2 - ,基团R各自独立地为氢,C 1-6 - 烷基,C 3-6 - 环烷基,其中一个或多个H原子可以被替换 通过卤素,基团R'各自独立地为C 1-4 - 烷基,卤素,指数n各自彼此独立地为0,1,2或3,随后羟基与 表氯醇,薄膜蒸发器或短程蒸发器,温度范围为150至270℃,压力范围为0.001至1毫巴。
    • 10. 发明授权
    • Preparation for the production of 1,2,4-triazolylmethyl-oxiranes
    • 制备1,2,4-三唑基甲基环氧乙烷
    • US07368464B2
    • 2008-05-06
    • US10516727
    • 2003-06-06
    • Rainer NoackMichael SanderMichael Henningsen
    • Rainer NoackMichael SanderMichael Henningsen
    • A61K31/41C07D249/08
    • C07D249/08C07D231/12C07D233/56
    • The present invention relates to a process for the preparation of 1,2,4-triazol-1-ylmethyloxiranes of the formula I in which A and B are identical or different and, independently of one another, are C1-C4-alkyl, phenyl-C1-C2-alkyl, C3-C6-cycloalkyl, C3-C6-cycloalkenyl, tetrahydropyranyl, tetrahydrofuranyl, dioxanyl or phenyl, where the phenyl radical can carry one to three substituents chosen from the group: halogen, nitro, C1-C4-alkyl, Cl-C4-alkyloxy, phenoxy, amino, C1-C2-haloalkyl or phenylsulfonyl, which comprises reacting a) an oxirane of the formula II in which A and B have the meanings given above and L is a nucleophilically substitutable leaving group, with 4-amino-1,2,4-triazole of the formula III to give 4-amino-1,2,4-triazolium salts of the formula IV and b) deaminating the 4-amino-1,2,4-triazolium salts IV with alkali metal nitrites and acid or organic nitrites to give 1,2,4-triazol-1-ylmethyloxiranes of the formula I, and to 4-aminotriazolium salts of the formula IV as intermediates.
    • 本发明涉及制备式I的1,2,4-三唑-1-基甲基环氧烷的方法,其中A和B相同或不同,且彼此独立地为C 1〜 C 1 -C 4 - 亚烷基,苯基-C 1 -C 2 - 烷基,C 3 -C C 6 -C 6 - 环烷基,C 3 -C 6 - 环烯基,四氢吡喃基,四氢呋喃基,二烷基或苯基,其中苯基可以携带一至三个 选自以下的取代基:卤素,硝基,C 1 -C 4 - 烷基,C 1 -C 4 - 烷氧基,苯氧基,氨基,C 1 -C 2 - 卤代烷基或苯基磺酰基,其包括使a)式A的环氧乙烷与A和B具有式 L是具有式III的4-氨基-1,2,4-三唑的亲核可取代的离去基团,得到式IV的4-氨基-1,2,4-三唑鎓盐,和b)脱氨基 具有碱金属元素的4-氨基-1,2,4-三唑鎓盐IV l亚硝酸盐和酸或有机亚硝酸盐,得到式I的1,2,4-三唑-1-基甲基环氧乙烷和作为中间体的式IV的4-氨基三唑鎓盐。