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1. 发明申请

US20060111749A1 System for providing emergency medical care with real-time instructions and associated methods 有权
标题翻译：提供紧急医疗护理的实时指导和相关方法的系统
公开(公告)号：US20060111749A1
公开(公告)日：2006-05-25
申请号：US11157218
申请日：2005-06-20
申请人： Dwayne Westenskow , Joseph Orr , Noah Syroid , Daniel Snell , James Agutter , Frank Drews , Srinath Lingutta , Santosh Balakrishnan , Kai Kuck , Lara Brewer
发明人： Dwayne Westenskow , Joseph Orr , Noah Syroid , Daniel Snell , James Agutter , Frank Drews , Srinath Lingutta , Santosh Balakrishnan , Kai Kuck , Lara Brewer
IPC分类号： A61N1/39
CPC分类号： G09B19/00 , A61M16/0051 , A61M16/024 , A61M16/1055 , A61M16/106 , A61M2205/502 , A61M2205/581 , A61M2205/583 , A61M2230/04 , A61M2230/205 , A61M2230/42 , A61M2230/432 , A61N1/39 , A61N1/3993 , G09B23/288
摘要： A basic life support system (BLSS) includes a processing element and an output element, such as a display screen or an audio output element, for providing an individual with real-time instructions on providing emergency medical care to a patient until paramedics or other healthcare professionals arrive to take over care for the patient. The instructions may be provided as graphics, including animations, as text, audibly, or as a combination of visible and audible elements. The BLSS may be configured for providing emergency medical care to individuals who have suffered from ventricular fibrillation. Accordingly, the BLSS may also include a defibrillation apparatus, an air or oxygen supply, a respiratory interface, one or more sensors, or a combination thereof.
摘要翻译：基本生命支持系统（BLSS）包括处理元件和诸如显示屏或音频输出元件的输出元件，用于向个人提供关于向患者提供紧急医疗护理的实时指令，直到护理人员或其他保健专业人员到医院接受治疗。指令可以作为图形，包括动画，文本，听觉地或作为可见和可听元素的组合来提供。 BLSS可能被配置为为患有心室颤动的个人提供紧急医疗。因此，BLSS还可以包括除颤装置，空气或氧气供应，呼吸界面，一个或多个传感器或其组合。

2. 发明授权

US07699788B2 Noninvasive effective lung volume estimation 有权
标题翻译：无创有效肺容量估计
公开(公告)号：US07699788B2
公开(公告)日：2010-04-20
申请号：US10973815
申请日：2004-10-25
申请人： Kai Kuck , Joseph Orr , Lara Brewer
发明人： Kai Kuck , Joseph Orr , Lara Brewer
IPC分类号： A61B5/00
CPC分类号： A61B5/0836 , A61B5/091
摘要： Methods for noninvasively measuring, or estimating, functional residual capacity or effective lung volume include obtaining carbon dioxide and flow measurements at or near the mouth of a subject. Such measurements are obtained during baseline breathing and during and shortly after inducement of a change in the subject's effective ventilation. The obtained measurements are evaluated to determine the amount of time required for exhaled carbon dioxide levels to return to normal—effectively an evaluation of carbon dioxide “washout” from the subject's lungs. Conversely, carbon dioxide and flow measurements may be evaluated to determine the amount of time it takes carbon dioxide to “wash in,” or reach peak levels within, the lungs of the subject following the change in the subject's effective ventilation. Apparatus for effective such methods are also disclosed.
摘要翻译：用于非侵入性测量或估计功能残余容量或有效肺体积的方法包括在受试者的嘴部或附近获得二氧化碳和流量测量。在基线呼吸期间和受试者的有效通气改变之后及之后不久，获得这些测量。评估所获得的测量值，以确定呼出二氧化碳水平回复正常有效地评估受试者肺部二氧化碳“冲洗”所需的时间。相反，可以评估二氧化碳和流量测量，以确定在受试者有效通气改变之后二氧化碳“洗涤”所需的时间，或达到受试者肺部内的峰值水平。还公开了用于有效的这种方法的装置。

3. 发明申请

US20060004297A1 Lung model-based cardiopulmonary performance determination 审中-公开
标题翻译：肺型心肺功能测定
公开(公告)号：US20060004297A1
公开(公告)日：2006-01-05
申请号：US11150378
申请日：2005-06-10
申请人： Joseph Orr , Kai Kuck , Lara Brewer
发明人： Joseph Orr , Kai Kuck , Lara Brewer
IPC分类号： A61B5/08
CPC分类号： A61B5/029 , A61B5/082 , A61B5/083 , A61B5/0836 , A61B5/087 , A61B5/091 , G01N33/497
摘要： Methods for noninvasively evaluating indicators of cardio-pulmonary performance of a subject, such as cardiac output, pulmonary capillary blood flow, and blood carbon dioxide content, include obtaining data of an expiratory carbon dioxide signal and comparing data generated by an algorithmic lung model to the data of the expiratory carbon dioxide signal of a subject. The variables that are input into the algorithmic lung model are adjusted until the data generated thereby reflects that of the measured expiratory carbon dioxide signal with a desired degree of accuracy. Once the algorithmic lung model replicates the data of the measured expiratory carbon dioxide signal with the desired degree of accuracy, one or more of the input values may be used to determine one or more of the cardiac output, pulmonary capillary blood flow, or a blood gas content of the subject from which the expiratory carbon dioxide signal was obtained.
摘要翻译：用于非侵入性评估受试者的心肺功能指标（如心输出量，肺毛细血管血流量和血二氧化碳含量）的方法包括获得呼气二氧化碳信号的数据，并将算法肺模型产生的数据与受检者呼气二氧化碳信号的数据。调整输入到算法肺模型中的变量，直到由此产生的数据以所需的准确程度反映测量的呼气二氧化碳信号的数据。一旦算法肺模型以期望的准确度复制测量的呼气二氧化碳信号的数据，则一个或多个输入值可用于确定心输出量，肺毛细血管血流量或血液中的一个或多个获得呼气二氧化碳信号的对象的气体含量。

4. 发明申请

US20050177055A1 Algorithms, systems, and methods for estimating carbon dioxide stores, transforming respiratory gas measurements, and obtaining accurate noninvasive pulmonary capillary blood flow and cardiac output measurements 有权
标题翻译：用于估算二氧化碳储存，转化呼吸气体测量和获得准确无创肺毛细血管血流量和心输出量测量的算法，系统和方法
公开(公告)号：US20050177055A1
公开(公告)日：2005-08-11
申请号：US11102072
申请日：2005-04-08
申请人： Kai Kuck , Joseph Orr , Lara Brewer
发明人： Kai Kuck , Joseph Orr , Lara Brewer
IPC分类号： A61B5/026 , A61B5/08 , A61B5/083 , A61B5/087 , G01N1/22 , A61M15/00 , A61M16/10
CPC分类号： A61B5/0836 , A61B5/029 , G01N33/497 , G01N2001/2244
摘要： Methods for estimating the volume of the carbon dioxide stores of an individual's respiratory tract include determining a carbon dioxide store volume at which a correlation between corresponding signals of carbon dioxide elimination and an indicator of the content of carbon dioxide in blood of the individual is optimized. The estimate of the volume of carbon dioxide stores, which comprises a model of the respiratory tract, or lungs, of the individual, may be used as a transformation to improve the accuracy of one or both of the carbon dioxide elimination and carbon dioxide content signals. Transformation, or filtering, algorithms are also disclosed, as are systems in which the methods and algorithms may be used. The methods, algorithms, and systems may be used to accurately and noninvasively determine one or both of the pulmonary capillary blood flow and cardiac output of the individual.
摘要翻译：用于估计个体呼吸道二氧化碳储存体积的方法包括确定二氧化碳储存容积，其中二氧化碳消除的相应信号与个体血液中二氧化碳含量的指标被优化之间的相关性。包括个人呼吸道或肺的模型的二氧化碳储存量的估算可以用作改善二氧化碳消除和二氧化碳含量信号中的一种或两种的准确性的转化。还公开了转换或滤波算法，以及可以使用方法和算法的系统。方法，算法和系统可用于精确地和非侵入性地确定个体的肺毛细血管血流量和心输出量中的一个或两个。

5. 发明申请

US20060253038A1 Methods and apparatus for improving time domain relationships between signals obtained from respiration 有权
公开(公告)号：US20060253038A1
公开(公告)日：2006-11-09
申请号：US11483460
申请日：2006-07-10
申请人： Kai Kuck , Joseph Orr , Lara Brewer
发明人： Kai Kuck , Joseph Orr , Lara Brewer
IPC分类号： A61B5/02 , G01N33/497 , A61B5/08
CPC分类号： A61B5/0836 , A61B5/029 , G01N33/497 , G01N2001/2244
摘要： Methods for estimating the volume of the carbon dioxide stores of an individual's respiratory tract include determining a carbon dioxide store volume at which a correlation between corresponding signals of carbon dioxide elimination and an indicator of the content of carbon dioxide in blood of the individual is optimized. The estimate of the volume of carbon dioxide stores, which comprises a model of the respiratory tract, or lungs, of the individual, may be used as a transformation to improve the accuracy of one or both of the carbon dioxide elimination and carbon dioxide content signals. Transformation, or filtering, algorithms are also disclosed, as are systems in which the methods and algorithms may be used. The methods, algorithms, and systems may be used to accurately and noninvasively determine one or both of the pulmonary capillary blood flow and cardiac output of the individual.

6. 发明申请

US20050124907A1 Noninvasive effective lung volume estimation 有权
标题翻译：无创有效肺容量估计
公开(公告)号：US20050124907A1
公开(公告)日：2005-06-09
申请号：US10973815
申请日：2004-10-25
申请人： Kai Kuck , Joseph Orr , Lara Brewer
发明人： Kai Kuck , Joseph Orr , Lara Brewer
IPC分类号： A61B5/083 , A61B5/091 , G01N1/22 , A61B5/08 , B32B5/02 , G01N31/00 , G01N33/497
CPC分类号： A61B5/0836 , A61B5/091
摘要： Methods for noninvasively measuring, or estimating, functional residual capacity or effective lung volume include obtaining carbon dioxide and flow measurements at or near the mouth of a subject. Such measurements are obtained during baseline breathing and during and shortly after inducement of a change in the subject's effective ventilation. The obtained measurements are evaluated to determine the amount of time required for exhaled carbon dioxide levels to return to normal—effectively an evaluation of carbon dioxide “washout” from the subject's lungs. Conversely, carbon dioxide and flow measurements may be evaluated to determine the amount of time it takes carbon dioxide to “wash in,” or reach peak levels within, the lungs of the subject following the change in the subject's effective ventilation. Apparatus for effective such methods are also disclosed.
摘要翻译：用于非侵入性测量或估计功能残余容量或有效肺体积的方法包括在受试者的嘴部或附近获得二氧化碳和流量测量。在基线呼吸期间和受试者的有效通气改变之后及之后不久，获得这些测量。评估所获得的测量值，以确定呼出二氧化碳水平回复正常有效地评估受试者肺部二氧化碳“冲洗”所需的时间。相反，可以评估二氧化碳和流量测量，以确定在受试者有效通气改变之后二氧化碳“洗涤”所需的时间，或达到受试者肺部内的峰值水平。还公开了用于有效的这种方法的装置。

7. 发明授权

US08800561B2 System, method and apparatus for removal of volatile anesthetics for malignant hyperthermia 有权
标题翻译：用于去除恶性高热的挥发性麻醉剂的系统，方法和装置
公开(公告)号：US08800561B2
公开(公告)日：2014-08-12
申请号：US13600952
申请日：2012-08-31
申请人： Joseph Orr , Dwayne Westenskow , Derek Sakata
发明人： Joseph Orr , Dwayne Westenskow , Derek Sakata
IPC分类号： A62B7/10 , A62B19/00 , A62B23/02 , A61M16/00
CPC分类号： A61M16/009 , A61M16/0093 , A61M16/0816 , A61M16/105 , A61M16/1065 , A61M16/107
摘要： Systems, methods, and apparatus for removing volatile anesthetics from an anesthesia or ventilation system to minimize the effects of malignant hyperthermia in susceptible patients. According to one aspect of the present invention, a system for removing volatile anesthetics is provided. A first filter component placed in fluid communication with an inspiratory limb of an anesthesia or ventilation system such that volatile anesthetics will pass through the first filter component during operation of the anesthesia or ventilation system. A second filter component is operably coupled to the expiration port of the anesthesia or ventilation system such that gases passing through the expiratory limb of the anesthesia or ventilation system pass through the second filter component. The first filter component and second filter component are adapted to effectively remove volatile anesthetics passing through the respective filters.
摘要翻译：用于从麻醉或通气系统中去除挥发性麻醉剂的系统，方法和装置，以最小化易感患者的恶性高热的影响。根据本发明的一个方面，提供了一种用于除去挥发性麻醉剂的系统。第一过滤器部件与麻醉或通气系统的吸气肢流体连通，使得挥发性麻醉剂在麻醉或通气系统的操作期间将通过第一过滤器部件。第二过滤器部件可操作地联接到麻醉或通气系统的呼气端口，使得穿过麻醉或通气系统的呼气肢体的气体通过第二过滤器部件。第一过滤器部件和第二过滤器部件适于有效地去除通过各个过滤器的挥发性麻醉剂。

8. 发明申请

US20120325213A1 System, Method and Apparatus for Removal of Volatile Anesthetics for Malignant Hyperthermia 有权
标题翻译：用于去除恶性热疗挥发性麻醉剂的系统，方法和装置
公开(公告)号：US20120325213A1
公开(公告)日：2012-12-27
申请号：US13600952
申请日：2012-08-31
申请人： Joseph Orr , Dwayne Westenskow , Derek Sakata
发明人： Joseph Orr , Dwayne Westenskow , Derek Sakata
IPC分类号： A61M16/01 , A61M16/00
CPC分类号： A61M16/009 , A61M16/0093 , A61M16/0816 , A61M16/105 , A61M16/1065 , A61M16/107
摘要： Systems, methods, and apparatus for removing volatile anesthetics from an anesthesia or ventilation system to minimize the effects of malignant hyperthermia in susceptible patients. According to one aspect of the present invention, a system for removing volatile anesthetics is provided. A first filter component placed in fluid communication with an inspiratory limb of an anesthesia or ventilation system such that volatile anesthetics will pass through the first filter component during operation of the anesthesia or ventilation system. A second filter component is operably coupled to the expiration port of the anesthesia or ventilation system such that gases passing through the expiratory limb of the anesthesia or ventilation system pass through the second filter component. The first filter component and second filter component are adapted to effectively remove volatile anesthetics passing through the respective filters.
摘要翻译：用于从麻醉或通气系统中去除挥发性麻醉剂的系统，方法和装置，以最小化易感患者的恶性高热的影响。根据本发明的一个方面，提供了一种用于除去挥发性麻醉剂的系统。第一过滤器部件与麻醉或通气系统的吸气肢流体连通，使得挥发性麻醉剂在麻醉或通气系统的操作期间将通过第一过滤器部件。第二过滤器部件可操作地联接到麻醉或通气系统的呼气端口，使得穿过麻醉或通气系统的呼气肢体的气体通过第二过滤器部件。第一过滤器部件和第二过滤器部件适于有效地去除通过各个过滤器的挥发性麻醉剂。

9. 发明申请

US20100269828A1 SYSTEM, METHOD AND APPARATUS FOR REMOVAL OF VOLATILE ANESTHETICS FOR MALIGNANT HYPERTHERMIA 有权
标题翻译：用于移除恶性高血压的挥发性麻醉药物的系统，方法和装置
公开(公告)号：US20100269828A1
公开(公告)日：2010-10-28
申请号：US12431644
申请日：2009-04-28
申请人： Joseph Orr , Dwayne Westenskow , Derek Sakata
发明人： Joseph Orr , Dwayne Westenskow , Derek Sakata
IPC分类号： A61M16/00
CPC分类号： A61M16/009 , A61M16/0093 , A61M16/0816 , A61M16/105 , A61M16/1065 , A61M16/107
摘要： Systems, methods, and apparatus for removing volatile anesthetics from an anesthesia or ventilation system to minimize the effects of malignant hyperthermia in susceptible patients. According to one aspect of the present invention, a system for removing volatile anesthetics is provided. A first filter component placed in fluid communication with an inspiratory limb of an anesthesia or ventilation system such that volatile anesthetics will pass through the first filter component during operation of the anesthesia or ventilation system. A second filter component is operably coupled to the expiration port of the anesthesia or ventilation system such that gases passing through the expiratory limb of the anesthesia or ventilation system pass through the second filter component. The first filter component and second filter component are adapted to effectively remove volatile anesthetics passing through the respective filters.
摘要翻译：用于从麻醉或通气系统中去除挥发性麻醉剂的系统，方法和装置，以最小化易感患者的恶性高热的影响。根据本发明的一个方面，提供了一种用于除去挥发性麻醉剂的系统。第一过滤器部件与麻醉或通气系统的吸气肢流体连通，使得挥发性麻醉剂在麻醉或通气系统的操作期间将通过第一过滤器部件。第二过滤器部件可操作地联接到麻醉或通气系统的呼气端口，使得穿过麻醉或通气系统的呼气肢体的气体通过第二过滤器部件。第一过滤器部件和第二过滤器部件适于有效地去除通过各个过滤器的挥发性麻醉剂。

10. 发明申请

US20060129054A1 Methods for non-invasivelyestimating pulmonary capillary blood flow or cardiac output 审中-公开
标题翻译：非侵入性地测量肺毛细血管血流量或心输出量的方法
公开(公告)号：US20060129054A1
公开(公告)日：2006-06-15
申请号：US11346913
申请日：2006-02-03
申请人： Joseph Orr , Michael Jaffe , Scott Kofoed , Dwayne Westenskow
发明人： Joseph Orr , Michael Jaffe , Scott Kofoed , Dwayne Westenskow
IPC分类号： A61B5/08 , G01N33/497 , F41A19/00
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Methods for non-invasively determining the cardiac output or pulmonary capillary blood flow of a subject include monitoring the subject's respiration during two ventilatory states. Such a method may include determining parameters of at least one of the ventilatory states based on one or more characteristics of the subject. Data obtained from monitoring the subject's respiration, such as an amount of gas present in exhaled gases and respiratiory flow, may be used to estimate respiratory or blood gas parameters, such as an amount of gas exchanged between blood and gases in the subject's lungs or an indicator of a content of the gas in the subject's blood.
摘要翻译：非侵入性地确定受试者的心输出量或肺毛细血管血流量的方法包括在两个通气状态期间监测受试者的呼吸。这种方法可以包括基于受试者的一个或多个特征确定至少一个通气状态的参数。通过监测受试者的呼吸获得的数据，例如呼出气体和呼吸气流中存在的气体的量可用于估计呼吸或血液气体参数，例如受试者的肺中血液和气体之间交换的气体量对象血液中气体含量的指标。

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