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1. 发明申请

US20080300664A1 METHOD AND APPARATUS FOR PLACING A CORONARY SINUS/CARDIAC VEIN PACING AND DEFIBRILLATION LEAD WITH ADJUSTABLE ELECTRODE SPACING 审中-公开
标题翻译：用于放置可调节电极间隔的冠状动脉/心脏瓣膜和断裂引线的方法和装置
公开(公告)号：US20080300664A1
公开(公告)日：2008-12-04
申请号：US12115961
申请日：2008-05-06
申请人： DOUGLAS S. HINE , John L. Sommer , James H. Vaughan , Rick D. McVenes , Paulus C. Van Venrooij , Pierre-Andre Grandjean
发明人： DOUGLAS S. HINE , John L. Sommer , James H. Vaughan , Rick D. McVenes , Paulus C. Van Venrooij , Pierre-Andre Grandjean
IPC分类号： A61N1/05 , A61B5/042
CPC分类号： A61N1/056 , A61F2/88 , A61F2/958 , A61N2001/0585
摘要： A medical electrical lead, which may be useful in coupling an implantable medical device, is comprised of a first and second lead. The first lead has a first electrode coupled adjacent a distal end portion thereof. The distal end portion of the first lead is anchorable in the coronary sinus of a patient. The second lead is coupled with and moveable along the first lead. The second lead has a second electrode located thereon wherein the position of the first and second electrodes may be varied relative to one another by movement of the second lead along the first lead. A rubber tip holds the relative position of each electrode.
摘要翻译：可用于联接可植入医疗装置的医用电引线由第一和第二引线组成。第一引线具有邻近其远端部分耦合的第一电极。第一引线的远端部分可锚定在患者的冠状窦中。第二个领先者与第一个领先者相结合并可以移动。第二引线具有位于其上的第二电极，其中第一和第二电极的位置可以通过第二引线沿着第一引线的移动而相对于彼此变化。橡胶尖端保持每个电极的相对位置。

2. 发明授权

US07386351B2 Method and apparatus for placing a coronary sinus/cardiac vein pacing and defibriliation lead with adjustable electrode spacing 有权
标题翻译：用于放置冠状窦/心静脉起搏和除颤引线的方法和装置，具有可调节的电极间距
公开(公告)号：US07386351B2
公开(公告)日：2008-06-10
申请号：US10136777
申请日：2002-04-30
申请人： Douglas S. Hine , John L. Sommer , James H. Vaughan , Rick D. McVenes , Paulus C Van Venrooij , Pierre-Andre Grandjean
发明人： Douglas S. Hine , John L. Sommer , James H. Vaughan , Rick D. McVenes , Paulus C Van Venrooij , Pierre-Andre Grandjean
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61F2/88 , A61F2/958 , A61N2001/0585
摘要： A medical electrical lead, which may be useful in coupling an implantable medical device, is comprised of a first and second lead. The first lead has a first electrode coupled adjacent a distal end portion thereof. The distal end portion of the first lead is anchorable in the coronary sinus of a patient. The second lead is coupled with and moveable along the first lead. The second lead has a second electrode located thereon wherein the position of the first and second electrodes may be varied relative to one another by movement of the second lead along the first lead. A rubber tip holds the relative position of each electrode.
摘要翻译：可用于联接可植入医疗装置的医用电引线由第一和第二引线组成。第一引线具有邻近其远端部分耦合的第一电极。第一引线的远端部分可锚定在患者的冠状窦中。第二个领先者与第一个领先者相结合并可以移动。第二引线具有位于其上的第二电极，其中第一和第二电极的位置可以通过第二引线沿着第一引线的移动而相对于彼此变化。橡胶尖端保持每个电极的相对位置。

3. 发明授权

US6144882A Medical electrical lead 失效
标题翻译：医用电线
公开(公告)号：US6144882A
公开(公告)日：2000-11-07
申请号：US895977
申请日：1997-07-17
申请人： John L. Sommer , Rick D. McVenes , Douglas Hine
发明人： John L. Sommer , Rick D. McVenes , Douglas Hine
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A cardiac pacing lead for use in the coronary sinus and coronary veins. The lead is provided with a lead body configured to exhibit a curved configuration along a distal portion thereof, induced to maintain a portion of the curved configuration solely by means of a portion of a polyurethane lead body formed to display the curved configuration and wherein the lead conductor is freely mounted within the segment. The curved configuration includes first and second arcuate segments together providing a single-plane curvature of approximately 180 degrees, separated by a generally straight segment, the first segment having a greater length and greater arc of curvature than the second segment. The lead body encloses a first conductive coil coupled to an electrode mounted to the distal end of the lead body and a second elongated conductive coil is also located within the lead body and extends to a transition point proximal to the distal end of the first coil conductor, the second coil terminating within the lead body and insulated from the exterior of the lead body. The first conductive coil has a generally straight configuration and the distal portion of the second coil is formed to define a curve.
摘要翻译：用于冠状窦和冠状静脉的心脏起搏导联。引线设置有引线主体，其被构造成沿着其远端部分呈现弯曲的构造，被引导以仅通过形成为显示弯曲构造的聚氨酯引线体的一部分来维持弯曲构造的一部分，并且其中引线导体自由地安装在片段内。弯曲构造包括第一和第二弓形段，其一起提供大致180度的单平面曲率，由大致直的段分开，第一段具有比第二段更大的长度和更大的曲率弧。引线体包围耦合到安装到引线主体的远端的电极的第一导电线圈，并且第二细长导电线圈也位于引线主体内并且延伸到靠近第一线圈导体的远端的过渡点，所述第二线圈终止于所述引线体内并与所述引线体的外部绝缘。第一导电线圈具有大致直的构造，并且第二线圈的远端部分形成为限定曲线。

4. 发明授权

US05999858A Medical electrical lead 有权
标题翻译：医用电线
公开(公告)号：US05999858A
公开(公告)日：1999-12-07
申请号：US196860
申请日：1998-11-20
申请人： John L. Sommer , Rick D. McVenes , Douglas Hine
发明人： John L. Sommer , Rick D. McVenes , Douglas Hine
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0585
摘要： A cardiac pacing lead for use in the coronary sinus and coronary veins. The lead is provided with a lead body configured to exhibit a curved configuration along a distal portion thereof, induced to maintain a portion of the curved configuration solely by a portion of a polyurethane lead body formed to display the curved configuration and wherein the lead conductor is freely mounted within the segment The curved configuration includes first and second arcuate segments together providing a single-plane curvature of approximately 180 degrees, separated by a generally straight segment, the first segment having a greater length and greater arc of curvature than the second segment. The lead body encloses a first conductive coil coupled to an electrode mounted to the distal end of the lead body and a second elongated conductive coil is also located within the lead body and extends to a transition point proximal to the distal end of the first coil conductor, the second coil terminating within the lead body and insulated from the exterior of the lead body. The first conductive coil has a generally straight configuration and the distal portion of the second coil is formed to define a curve.
摘要翻译：用于冠状窦和冠状静脉的心脏起搏导联。引线设置有引线主体，其被构造成沿着其远端部分呈现弯曲构造，被引导以仅保持弯曲构造的一部分由形成为显示弯曲构造的聚氨酯引线体的一部分，并且其中引线导体为自由地安装在段内弯曲构造包括第一和第二弓形段，其一起提供大致180度的单平面曲率，由大致直的段分开，第一段具有比第二段更大的长度和更大的曲率弧。引线体包围耦合到安装到引线主体的远端的电极的第一导电线圈，并且第二细长导电线圈也位于引线主体内并且延伸到靠近第一线圈导体的远端的过渡点，所述第二线圈终止于所述引线体内并与所述引线体的外部绝缘。第一导电线圈具有大致直的构造，并且第二线圈的远端部分形成为限定曲线。

5. 发明授权

US07797047B2 Implantable lead functional status monitor and method 有权
标题翻译：可植入式铅功能状态监测和方法
公开(公告)号：US07797047B2
公开(公告)日：2010-09-14
申请号：US10781426
申请日：2004-02-18
申请人： David J. Jorgenson , Ross O. Starkson , Rick D. McVenes , Charles D. Trautmann , John D. Wahlstrand , Bradley C. Peck
发明人： David J. Jorgenson , Ross O. Starkson , Rick D. McVenes , Charles D. Trautmann , John D. Wahlstrand , Bradley C. Peck
IPC分类号： A61N1/362
CPC分类号： A61N1/3925 , A61N1/3706 , A61N2001/083
摘要： An implantable medical device (IMD) includes a lead status monitoring system. The lead status monitoring system employs a method including the steps of: collecting data sets from a lead impedance source, a stimulation threshold source, and at least one additional source included in the IMD; and processing the data sets to determine if a lead status event has occurred.
摘要翻译：可植入医疗装置（IMD）包括引导状态监测系统。引导状态监视系统采用的方法包括以下步骤：从引线阻抗源，刺激阈值源和IMD中包括的至少一个附加源收集数据集; 并处理数据集以确定是否发生了引导状态事件。

6. 发明授权

US08827982B2 Pre-formed delivery catheters 有权
标题翻译：预先形成的输送导管
公开(公告)号：US08827982B2
公开(公告)日：2014-09-09
申请号：US11680194
申请日：2007-02-28
申请人： Johnson E. Goode , Melissa Gene Tanner Christie , Stanten C. Spear , Rick D. McVenes
发明人： Johnson E. Goode , Melissa Gene Tanner Christie , Stanten C. Spear , Rick D. McVenes
IPC分类号： A61M25/00 , A61M25/06
CPC分类号： A61M25/0662 , A61M25/0041 , A61M25/0053 , A61M25/0152 , A61M2210/122 , A61M2210/125 , A61N1/0587
摘要： A delivery catheter includes a pre-formed and resilient heart-wrapping segment. The segment may have a relaxed span that allows the segment to wrap around a left side of a heart from an anterior epicardial surface to a posterior epicardial surface, when the catheter is advanced along the epicardial surface, having been inserted from a sub-xiphoid access site.
摘要翻译：输送导管包括预形成和弹性的心包裹部分。该段可以具有松弛的跨度，当导管沿着心外膜表面前进时，该区段从心脏的前心外膜表面到后心外膜表面包围心脏的左侧现场。

7. 发明授权

US06317633B1 Implantable lead functional status monitor and method 有权
标题翻译：可植入式铅功能状态监测和方法
公开(公告)号：US06317633B1
公开(公告)日：2001-11-13
申请号：US09487562
申请日：2000-01-19
申请人： David J. Jorgenson , Ross O. Starkson , Rick D. McVenes , Charles D. Trautmann , John D. Wahlstrand , Bradley C. Peck
发明人： David J. Jorgenson , Ross O. Starkson , Rick D. McVenes , Charles D. Trautmann , John D. Wahlstrand , Bradley C. Peck
IPC分类号： A61N137
CPC分类号： A61N1/08 , A61N1/3706
摘要： An implantable medical device (IMD) coupled with leads extending to body tissue providing storage of lead related data, monitoring of lead functional status, and indication of lead integrity to the clinician. A lead status monitor (LSM) processes lead related data in a system self test mode and provides a lead status report that identifies and declares conductor/connector issues, insulation issues, and electrode/tissue interface issues indicative of suspected lead related condition mechanisms for each lead employed in the IMD. The LSM operates employing a set of LSM rules that process measured lead impedance values and loss of capture (LOC) values. In a pacing system, particular LSM rules are defined that process periodically determined, pacing pulse characteristic at LOC and bipolar and unipolar lead impedance values that are measured periodically. The lead impedance values are compared to upper and lower limits or trip points of a normal impedance range. Simultaneously, significant changes in lead impedance are detected, and the unipolar impedance value is compared to the bipolar lead impedance value of each lead. Counts of deviations in lead impedances satisfying each LSM rule are maintained. Certain of the lead related condition mechanisms are declared if a count of lead impedance deviations meets a programmed threshold number of such lead impedance deviations within a further programmed number of sequential impedance measurements. Preferably, the pacing pulse strength or voltage at LOC (characterized as LOC_RHEOBASE herein) is periodically determined and compared to a reference LOC_RHEOBASE.
摘要翻译：与可延伸到身体组织的引线耦合的可植入医疗装置（IMD），提供铅相关数据的存储，铅功能状态的监测以及针对临床医生的铅完整性的指示。引导状态监视器（LSM）在系统自检模式下处理引导相关数据，并提供一个引导状态报告，用于识别和声明导体/连接器问题，绝缘问题和电极/组织界面问题，指示每个主管在IMD工作。 LSM使用一组LSM规则来处理测量的导线阻抗值和捕获损失（LOC）值。在起搏系统中，定义了特定的LSM规则，其在LOC处理周期性确定的起搏脉冲特性，并定期测量双极和单极性引线阻抗值。将引线阻抗值与正常阻抗范围的上限和下限或跳变点进行比较。同时，检测到引线阻抗的显着变化，并将单极性阻抗值与每个引线的双极引线阻抗值进行比较。保持满足每个LSM规则的引线阻抗偏差的计数。如果引导阻抗偏差的计数在另外编程的连续阻抗测量数量中达到这样的引线阻抗偏差的编程阈值数，则声明某些引线相关条件机制。优选地，周期性地确定LOC（此处表征为LOC_RHEOBASE）的起搏脉冲强度或电压，并将其与参考LOC_RHEOBASE进行比较。

8. 发明申请

US20100010469A1 PRE-FORMED DELIVERY CATHETERS 审中-公开
标题翻译：预先配送的导管
公开(公告)号：US20100010469A1
公开(公告)日：2010-01-14
申请号：US12563367
申请日：2009-09-21
申请人： Johnson E. Goode , Melissa Gene Tanner Christie , Stanten C. Spear , Rick D. McVenes
发明人： Johnson E. Goode , Melissa Gene Tanner Christie , Stanten C. Spear , Rick D. McVenes
IPC分类号： A61M25/00
CPC分类号： A61M25/0662 , A61M25/0041 , A61M25/0053 , A61M25/0152 , A61M2210/122 , A61M2210/125 , A61N1/0587
摘要： A delivery catheter includes a pre-formed and resilient heart-wrapping segment. The segment may have a relaxed span that allows the segment to wrap around a left side of a heart from an anterior epicardial surface to a posterior epicardial surface, when the catheter is advanced along the epicardial surface, having been inserted from a sub-xiphoid access site.
摘要翻译：输送导管包括预形成和弹性的心包裹部分。该段可以具有松弛的跨度，当导管沿着心外膜表面前进时，该区段从心脏的前心外膜表面到后心外膜表面包围心脏的左侧现场。

9. 发明授权

US06721600B2 Implantable lead functional status monitor and method 有权
标题翻译：可植入式铅功能状态监测和方法
公开(公告)号：US06721600B2
公开(公告)日：2004-04-13
申请号：US10039667
申请日：2001-12-31
申请人： David J. Jorgenson , Ross O. Starkson , Rick D. McVenes , Charles D. Trautmann , John D. Wahlstrand , Bradley C. Peck
发明人： David J. Jorgenson , Ross O. Starkson , Rick D. McVenes , Charles D. Trautmann , John D. Wahlstrand , Bradley C. Peck
IPC分类号： A61N118
CPC分类号： A61N1/3925 , A61N1/3706 , A61N2001/083
摘要： A system for monitoring trends in lead impedance includes collecting data from various sources in an implantable medical device system. Lead impedance, non-physiologic sensed events percentage of time in mode switch, results of capture management operation, sensed events, adversion pace counts, refractory sense counts and similar data are used to determine the status of a lead. A set of weighted sum rules are implemented by a software system to process the data and provide displayable information to health care professionals via a programmer. The lead monitoring system includes a patient alert system for patients to seek help in the event a serious lead condition is identified.
摘要翻译：用于监测引线阻抗趋势的系统包括在可植入医疗器械系统中收集来自各种来源的数据。引线阻抗，非生理感测事件模式切换时间的百分比，捕获管理操作的结果，感测事件，反转步伐计数，难度感知计数和类似数据用于确定引线的状态。一组加权和规则由软件系统实现，以处理数据，并通过程序员向医疗保健专业人员提供可显示的信息。牵头监测系统包括一个病人警报系统，用于在发现严重的领先条件的情况下为病人寻求帮助。

10. 发明授权

US5443492A Medical electrical lead and introducer system for implantable pulse generator 失效
标题翻译：用于植入式脉冲发生器的医用电气引线和引导系统
公开(公告)号：US5443492A
公开(公告)日：1995-08-22
申请号：US189565
申请日：1994-02-02
申请人： Kenneth B. Stokes , Keith J. Proctor , Rick D. McVenes
发明人： Kenneth B. Stokes , Keith J. Proctor , Rick D. McVenes
IPC分类号： A61N1/05 , A61N1/04
CPC分类号： A61N1/0568 , A61N1/0573 , A61N2001/0578
摘要： An implantable lead for establishing electrical contact between a medical device and body tissue, in which an active fixation mechanism secures the lead in place while allowing a distal electrode on the lead to mechanically "float" with respect to the body tissue. In one embodiment, the active fixation mechanism comprises a curved hook disposed on the lead at a point spaced proximally back from the distal end of the lead. The curved hook defines a helix around at least a portion of the lead's circumference. A hollow introducer needle is slidably disposed on the lead. The hollow needle provided with a longitudinal slit in a distal section of is length, such that the distal section of the needle can be advanced over the distal end of the lead, past the fixation hook, which is received in the longitudinal slit. With the needle slid over the distal end of the lead, the needle is stabbed tangentially into an implant site, bringing the fixation hook proximal to the surface of the body tissue. Then, the needle is twisted (bringing about a twisting of the lead), causing the curved fixation hook to pierce and engage the body tissue, securing the lead in place. Then the needle is withdrawn from the body tissue and removed from the lead. In an alternative embodiment, the lead can be placed by an endocardial approach using a flexible cannula with a longitudinally slotted tip.
摘要翻译：一种用于在医疗装置和身体组织之间建立电接触的可植入引线，其中主动固定机构将引线固定在适当位置，同时允许引线上的远端电极相对于身体组织机械地“浮动”。在一个实施例中，主动固定机构包括设置在引线上的远离引导件远端的近距离间隔的点的弯曲钩。弯曲的钩子围绕引线的周边的至少一部分限定螺旋。中空导引针可滑动地设置在引线上。中空针在远端部分设置有长度方向的狭缝，使得针的远端部分能够超过引线的远端延伸穿过容纳在纵向狭缝中的固定钩。当针滑过导线的远端时，针被切向地刺入植入部位，使固定钩靠近身体组织的表面。然后，针头扭转（导致引线扭转），导致弯曲的固定钩刺穿并接合身体组织，将导线固定到位。然后将针从身体组织中取出并从铅中取出。在替代实施例中，引线可以通过使用具有纵向开口尖端的柔性套管的心内膜方式放置。

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