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1. 发明授权

US6097025A Light detection device having an optical-path switching mechanism 有权
标题翻译：具有光路切换机构的光检测装置
公开(公告)号：US6097025A
公开(公告)日：2000-08-01
申请号：US160533
申请日：1998-09-24
申请人： Douglas N. Modlin , Glenn R. Edwards , Michael T. Taylor , Samuel A. Marquiss , Amer El-Hage , Craig S. Barker , Lorne B. Bechtel , Rick V. Stellmacher , Philip A. Granieri, Jr. , Robert M. Lembi, Sr.
发明人： Douglas N. Modlin , Glenn R. Edwards , Michael T. Taylor , Samuel A. Marquiss , Amer El-Hage , Craig S. Barker , Lorne B. Bechtel , Rick V. Stellmacher , Philip A. Granieri, Jr. , Robert M. Lembi, Sr.
IPC分类号： G01J1/36 , G01N21/25 , G01N21/64 , G01N21/76
CPC分类号： G01N21/76 , G01N21/253 , G01N21/6445 , G01N21/6452 , G01N2021/6417 , G01N2021/6471
摘要： A high-throughput light detection instrument and method are described. In some embodiments, switch mechanisms and optical relay structures permit different light sources and/or detectors to be selected for different applications. In other embodiments, switch mechanisms and optical paths permit top/bottom illumination and/or top/bottom detection, or combinations thereof.
摘要翻译：描述了高通量光检测仪器和方法。在一些实施例中，开关机构和光学继电器结构允许为不同的应用选择不同的光源和/或检测器。在其他实施例中，开关机构和光路允许顶部/底部照明和/或顶部/底部检测或其组合。

2. 发明授权

US06313960B2 Optical filter holder assembly 失效
标题翻译：光学过滤器支架组件
公开(公告)号：US06313960B2
公开(公告)日：2001-11-06
申请号：US09118141
申请日：1998-07-16
申请人： Samuel A. Marquiss , Calvin D. Wong , Glenn R. Edwards , Michael T. Taylor , Philip A. Granieri, Jr. , Douglas N. Modlin , Amer El-Hage
发明人： Samuel A. Marquiss , Calvin D. Wong , Glenn R. Edwards , Michael T. Taylor , Philip A. Granieri, Jr. , Douglas N. Modlin , Amer El-Hage
IPC分类号： G02B522
CPC分类号： G01N21/76 , B01J2219/00315 , B01J2219/00317 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00659 , B01J2219/00686 , B01J2219/00691 , B01J2219/00707 , B01L9/523 , B01L2300/0829 , B82Y15/00 , C40B60/14 , Y10S436/807 , Y10S436/809 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831 , Y10T436/25
摘要： Devices for using optical filters in a filter holder that enable optical filters to be simply, conveniently, and flexibly interchanged.
摘要翻译：在过滤器保持架中使用滤光器的设备，使滤光片简单，方便，灵活地互换。

3. 发明授权

US06499366B1 Sample feeder 失效
标题翻译：样品进料器
公开(公告)号：US06499366B1
公开(公告)日：2002-12-31
申请号：US09144578
申请日：1998-08-31
申请人： John W. Meadows , Glenn R. Edwards , Samuel A. Marquiss , Amer El-Hage , Douglas N. Modlin
发明人： John W. Meadows , Glenn R. Edwards , Samuel A. Marquiss , Amer El-Hage , Douglas N. Modlin
IPC分类号： G01N3504
CPC分类号： G01N21/76 , B01J2219/00315 , B01J2219/00317 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00659 , B01J2219/00686 , B01J2219/00691 , B01J2219/00707 , B01L9/523 , B01L2300/0829 , B82Y15/00 , C40B60/14 , Y10S436/807 , Y10S436/809 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831 , Y10T436/25
摘要： Devices for automatically feeding sample containers into and out of an analyzer. The device may include (1) a first station that receives and initiates transport of a sample container into an analyzer for analysis, (2) a second station where the sample container is handed off to a transporter that carries the sample container to and from an examination site inside the analyzer, and (3) a third station that collects the sample container after examination. The device also may include a singulation mechanism configured to separate a sample container from a stack of sample containers, and/or a stacking mechanism configured to add a sample container to a stack of sample containers. The singulation and stacking mechanisms may include lifter and latch components.
摘要翻译：用于自动将样品容器进出分析仪的装置。该设备可以包括（1）第一站，其接收和启动样品容器进入分析器进行分析，（2）第二站，其中样本容器被切换到将样品容器运送到和从分析仪内的检查点，（3）检查后收集样品容器的第三站。该装置还可以包括被配置为将样品容器与样品容器的堆叠分开的单一化机构和/或构造成将样品容器添加到样品容器堆叠的堆叠机构。分离和堆叠机构可以包括升降器和闩锁部件。

4. 发明授权

US06902703B2 Integrated sample-processing system 失效
标题翻译：综合样本处理系统
公开(公告)号：US06902703B2
公开(公告)日：2005-06-07
申请号：US09777343
申请日：2001-02-05
申请人： Samuel A. Marquiss , Christopher G. Cesar , Jon F. Petersen , David P. Stumbo , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin , Lev J. Leytes , Samuel Burd
发明人： Samuel A. Marquiss , Christopher G. Cesar , Jon F. Petersen , David P. Stumbo , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin , Lev J. Leytes , Samuel Burd
IPC分类号： B01L3/00 , C07F15/00 , C12Q1/68 , G01N21/25 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , B01L3/02
CPC分类号： G01N35/028 , B01L3/50853 , C07F15/0053 , C12Q1/6816 , C12Q1/6827 , G01N21/253 , G01N21/645 , G01N35/1011 , G01N35/1074 , G01N2035/00237 , G01N2035/0405 , G01N2035/0425 , G01N2035/0462 , Y10T436/11 , Y10T436/119163 , Y10T436/25 , Y10T436/2575 , C12Q2565/107
摘要： The invention provides an integrated sample-processing system and components thereof for preparing and/or analyzing samples. The components may include a transport module, a fluidics module, and an analysis module, among others.
摘要翻译：本发明提供了用于制备和/或分析样品的综合样品处理系统及其组件。组件可以包括传输模块，流体模块和分析模块等。

5. 发明授权

US06838051B2 Integrated sample-processing system 失效
公开(公告)号：US06838051B2
公开(公告)日：2005-01-04
申请号：US09778224
申请日：2001-02-06
申请人： Samuel A. Marquiss , Christopher G. Cesar , Jon F. Petersen , David P. Stumbo , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin , Ley J. Leytes , Samuel Burd
发明人： Samuel A. Marquiss , Christopher G. Cesar , Jon F. Petersen , David P. Stumbo , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin , Ley J. Leytes , Samuel Burd
IPC分类号： B01L3/00 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G01N21/00
CPC分类号： B01L3/50853 , G01N35/028 , G01N35/1011 , G01N35/1074 , G01N2035/00237 , G01N2035/0405 , G01N2035/0425 , G01N2035/0462 , Y10T436/112499 , Y10T436/114165
摘要： The invention provides an integrated sample-processing system and components thereof for preparing and/or analyzing samples. The components may include a transport module, a fluidics module, and an analysis module, among others.

6. 发明授权

US06187267B1 Chemiluminescence detection device 有权
标题翻译：化学发光检测装置
公开(公告)号：US06187267B1
公开(公告)日：2001-02-13
申请号：US09146081
申请日：1998-09-02
申请人： Michael T. Taylor , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin
发明人： Michael T. Taylor , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin
IPC分类号： G01N2117
CPC分类号： G01N21/76 , B01J2219/00315 , B01J2219/00317 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00659 , B01J2219/00686 , B01J2219/00691 , B01J2219/00707 , B01L9/523 , B01L2300/0829 , B82Y15/00 , C40B60/14 , Y10S436/807 , Y10S436/809 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831 , Y10T436/25
摘要： A device for detecting chemiluminescence from a sample. The device may include a stage for supporting a sample and one or more of the following elements: (1) an optics head, (2) an optical relay structure for transmitting chemiluminescence from the sample to a detector, (3) a drive mechanism, (4) a sensor for detecting proximity of the optical relay structure to the sample, (5) a mask structure for selecting an effective diameter of the optical relay structure, and (6) a baffle for blocking extraneous light from entering the optical relay structure.
摘要翻译：用于从样品中检测化学发光的装置。该装置可以包括用于支撑样品的台和以下元件中的一个或多个：（1）光学头，（2）用于将化学发光从样品传输到检测器的光中继结构，（3）驱动机构，（4）用于检测光继电器结构对样品的接近度的传感器，（5）用于选择光继电器结构的有效直径的掩模结构，以及（6）用于阻挡外来光进入光中继结构的挡板。

7. 发明授权

US06576476B1 Chemiluminescence detection method and device 失效
标题翻译：化学发光检测方法及装置
公开(公告)号：US06576476B1
公开(公告)日：2003-06-10
申请号：US09302158
申请日：1999-04-29
申请人： Michael T. Taylor , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin
发明人： Michael T. Taylor , Amer El-Hage , Glenn R. Edwards , Douglas N. Modlin
IPC分类号： G01N2117
CPC分类号： G01N21/253 , G01N21/76 , Y10T436/114165
摘要： A device for detecting chemiluminescence from a sample. The device may include a stage for supporting a sample and one or more of the following elements: (1) an optics head, (2) an optical relay structure for transmitting chemiluminescence from the sample to a detector, (3) a drive mechanism, (4) a sensor for detecting proximity of the optical relay structure to the sample, (5) a mask structure for selecting an effective diameter of the optical relay structure, and (6) a baffle for blocking extraneous light from entering the optical relay structure.
摘要翻译：用于从样品中检测化学发光的装置。该装置可以包括用于支撑样品的台和以下元件中的一个或多个：（1）光学头，（2）用于将化学发光从样品传输到检测器的光中继结构，（3）驱动机构，（4）用于检测光继电器结构对样品的接近度的传感器，（5）用于选择光继电器结构的有效直径的掩模结构，以及（6）用于阻挡外来光进入光中继结构的挡板。

8. 发明授权

US06025985A Moveable control unit for high-throughput analyzer 失效
标题翻译：可移动控制单元，用于高通量分析仪
公开(公告)号：US06025985A
公开(公告)日：2000-02-15
申请号：US118341
申请日：1998-07-16
申请人： Lev J. Leytes , William G. Burton , Yong Paik , Glenn R. Edwards , Douglas N. Modlin , Amer El-Hage
发明人： Lev J. Leytes , William G. Burton , Yong Paik , Glenn R. Edwards , Douglas N. Modlin , Amer El-Hage
IPC分类号： G01N21/64 , B01L9/00 , C40B60/14 , F21V21/18 , G01N21/03 , G01N21/17 , G01N21/21 , G01N21/27 , G01N21/76 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G06F1/16
CPC分类号： G01N21/76 , B01L9/523 , B82Y15/00 , B01J2219/00315 , B01J2219/00317 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00659 , B01J2219/00686 , B01J2219/00691 , B01J2219/00707 , B01L2300/0829 , C40B60/14 , Y10S436/807 , Y10S436/809 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/115831 , Y10T436/25
摘要： A moveable control unit for a high-throughput analyzer that can be operatively mounted at a plurality of locations on the analyzer housing.
摘要翻译：一种用于高通量分析仪的可移动控制单元，其可操作地安装在分析仪壳体上的多个位置处。

9. 发明授权

US5843378A Method of producing a probe for aspirating and dispensing probe having surface sensing capability 失效
标题翻译：用于产生具有表面感测能力的吸引和分配探针的探针的方法
公开(公告)号：US5843378A
公开(公告)日：1998-12-01
申请号：US790096
申请日：1997-01-29
申请人： Amer El-Hage , Rick V. Stellmacher
发明人： Amer El-Hage , Rick V. Stellmacher
IPC分类号： G01F23/24 , G01N35/10 , B01L3/02
CPC分类号： G01N35/1009 , G01F23/24 , G01F23/245 , G01N2035/1025 , Y10T436/2575
摘要： A method of producing a probe for aspirating and dispensing liquid. A fluid conduit and rod are positioned in the central bore of a tube so that an inlet end of the conduit and a contact end of the rod protrude from an upper end of the tube and a discharge end of the conduit and a sensing end of the rod protrude from a lower end of the tube. The tube has a heat-shrinkable outer layer and a meltable inner layer. The tube is heated so that its outer layer shrinks and its inner layer melts to encapsulate middle portions of the conduit and rod. A circuit board having first and second traces and first and second holes is placed on the upper end of the tube so that the inlet end of the conduit is inserted through the first hole and the contact end of the rod is inserted through the second hole. The conduit and rod are attached to the board so that the conduit is electrically connected to the first trace and the rod is electrically connected to the second trace. First and second conducting pins are also attached to the board. The conducting pins electrically connect the traces to a voltage sensing circuit when the probe is attached to a probe positioning device.
摘要翻译：一种生产用于吸入和分配液体的探针的方法。流体导管和杆定位在管的中心孔中，使得导管的入口端和杆的接触端从管的上端突出并且管的排出端和导管的感测端杆从管的下端突出。该管具有可热收缩的外层和可熔融的内层。加热管，使其外层收缩，其内层熔化以封装导管和棒的中间部分。具有第一和第二迹线和第一和第二孔的电路板被放置在管的上端，使得导管的入口端插入穿过第一孔，并且杆的接触端插入穿过第二孔。管道和杆被附接到板，使得导管电连接到第一迹线，并且杆电连接到第二迹线。第一和第二导电引脚也连接到电路板。当探针附接到探针定位装置时，导电引脚将迹线电连接到电压感测电路。

10. 发明授权

US06488892B1 Sample-holding devices and systems 有权
标题翻译：样品保持装置和系统
公开(公告)号：US06488892B1
公开(公告)日：2002-12-03
申请号：US09478819
申请日：2000-01-05
申请人： William G. Burton , Douglas N Modlin , Derrick A. Richardson , Jon F. Petersen , Joseph S. Leytes , John C. Owicki , Amer El-Hage , Lev J. Leytes
发明人： William G. Burton , Douglas N Modlin , Derrick A. Richardson , Jon F. Petersen , Joseph S. Leytes , John C. Owicki , Amer El-Hage , Lev J. Leytes
IPC分类号： G01N2129
CPC分类号： B01L9/523 , B01J2219/00315 , B01J2219/00317 , B01J2219/00605 , B01J2219/0061 , B01J2219/00621 , B01J2219/00659 , B01J2219/00686 , B01J2219/00691 , B01J2219/00707 , B01L2300/0829 , B82Y15/00 , C40B60/14 , G01N21/0303 , G01N35/028 , Y10T436/11
摘要： Sample-holding devices and systems for efficiently utilizing relatively small-volume fluid samples.
摘要翻译：用于有效利用相对小体积流体样品的样品保持装置和系统

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