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1. 发明申请

US20080086214A1 Medical device having a sleeve valve with bioactive agent 审中-公开
标题翻译：具有带有生物活性剂的套筒阀的医疗装置
公开(公告)号：US20080086214A1
公开(公告)日：2008-04-10
申请号：US11810307
申请日：2007-06-05
申请人： David Hardin , Kulwinder Dua , Gregory Skerven
发明人： David Hardin , Kulwinder Dua , Gregory Skerven
IPC分类号： A61F2/04
CPC分类号： A61F2/04 , A61F2/94 , A61F2002/041
摘要： Medical devices for implantation in a body vessel are provided. A medical device can be configured as a drainage stent adapted for placement in a bodily passageway. The drainage stent preferably includes a drainage lumen extending longitudinally through the drainage stent, and a sleeve defining a collapsible lumen in fluid flow communication with the drainage lumen. The sleeve may function as a one-way valve and preferably includes a biodeposition-reducing bioactive agent, such as an antibiotic or antimicrobial agent. The medical device may be configured as a biliary or pancreatic stent.
摘要翻译：提供用于植入体内的医疗装置。医疗装置可以被配置为适于放置在身体通道中的排水支架。排水支架优选地包括纵向延伸穿过排液支架的排液腔，以及限定与排液腔流体连通的可收缩腔的套筒。套筒可以用作单向阀，并且优选地包括生物沉积减少生物活性剂，例如抗生素或抗微生物剂。医疗装置可以被配置为胆管或胰支架。

2. 发明申请

US20070016306A1 Prosthesis having a sleeve valve 审中-公开
标题翻译：具有套筒阀的假体
公开(公告)号：US20070016306A1
公开(公告)日：2007-01-18
申请号：US11341970
申请日：2006-01-27
申请人： Kulwinder Dua , Gregory Skerven
发明人： Kulwinder Dua , Gregory Skerven
IPC分类号： A61F2/04 , A61F2/90
CPC分类号： A61F2/07 , A61F2/24 , A61F2/848 , A61F2/89 , A61F2220/0016 , A61F2220/0075 , A61F2230/0017 , A61F2230/0054 , A61F2230/0067 , A61F2250/0039
摘要： Disclosed is a pressure sensitive prosthesis that includes a tubular member having a passageway extending therethrough and a sleeve attached about one end of the tubular member. The sleeve functions as a one-way valve to permit fluid flowing through the sleeve lumen in a first, distal direction and under a first pressure, while collapsing in response to fluid flowing in a second direction when the pressure thereof exceeds that of the first direction or pressure. One aspect of the invention includes an esophageal anti-reflux expandable prosthesis wherein the sleeve is adapted to invert out of the tubular stent frame to permit belching or vomiting (fluid or materials under a third, higher pressure).
摘要翻译：公开了一种压敏假体，其包括具有延伸穿过其中的通道的管状构件和围绕管状构件的一端附接的套筒。套筒用作单向阀，以允许流体在第一远端方向和第一压力下流过套筒内腔，同时响应于当第二方向上的流体超过第一方向时流体流动而折叠或压力。本发明的一个方面包括食道抗回流可膨胀假体，其中套筒适于从管状支架框架反转以允许bel ching或呕吐（流体或第三，更高压力下的材料）。

3. 发明申请

US20050059890A1 System and method for introducing multiple medical devices 有权
标题翻译：引入多种医疗器械的系统和方法
公开(公告)号：US20050059890A1
公开(公告)日：2005-03-17
申请号：US10902625
申请日：2004-07-29
申请人： Stephen Deal , Matthew Carter , Victor Clark , Frederick Haller , David Hardin , John Karpiel , Kenneth Kennedy , Brian Rucker , Gregory Skerven , David Waller
发明人： Stephen Deal , Matthew Carter , Victor Clark , Frederick Haller , David Hardin , John Karpiel , Kenneth Kennedy , Brian Rucker , Gregory Skerven , David Waller
IPC分类号： A61B1/01 , A61B1/018 , A61B6/12 , A61B17/22 , A61F2/04 , A61M25/00 , A61M25/06 , A61B6/00
CPC分类号： A61B1/018 , A61B6/12 , A61B17/221 , A61B2017/2212 , A61F2/95 , A61F2002/041 , A61F2002/9511 , A61M25/0029 , A61M25/0662 , A61M25/10 , A61M2025/0183 , A61M2025/0681
摘要： A method and apparatus for introducing a first elongate medical device and short wire guide that are coupled together into a work site and remotely disconnecting them within the work site such that a secondary device comprising a catheter member can be introduced over the wire guide to the work site, and/or a second wire guide can be introduced to the work site via a passageway of the primary access device. A system of indicia, such as radiopaque or viewable markers, permit the operator to monitor the relative alignment of the devices within the work site to determine when uncoupling has occurred. In one example of the method, a wire guide and primary access device (e.g., a sphincterotome) is coupled to the wire guide and introduced via a duodenoscope into the biliary system. After performing a first medical operation, the devices are uncoupled with the wire guide being left within the biliary system such that a secondary access device, such as a balloon, biopsy device, stent delivery catheter, dilator, etc., can be introduced to perform a second medical operation without a traditional over-the-wire exchange being required. In another example of the method, a prosthesis, such as a valve or stent, is placed within the work site coupled to a wire guide which is remotely disconnected within the work site and a secondary device, such as a dilation balloon or second prosthesis, is introduced into the work site after the first delivery system is removed.
摘要翻译：一种用于引入第一细长医疗装置和短线引导件的方法和装置，所述第一细长医疗装置和短导线引导件联接在一起成为工作现场并在工作现场内远程地断开它们，使得包括导管部件的辅助装置可以被引导到导线器上，现场和/或第二导线引导件可以经由主接入设备的通道引入到工作现场。诸如不透射线或可见标记的标记系统允许操作者监视工作现场内的设备的相对对准以确定何时发生解偶联。在该方法的一个示例中，线导向器和主入口装置（例如括约肌切开机）联接到线导引件并经十二指肠镜引入胆道系统。在执行第一次医疗操作之后，将装置与线引导件脱离在胆汁系统内，使得可以引入二次进入装置，例如气囊，活检装置，支架输送导管，扩张器等，以执行不需要传统的线上交换即可进行第二次医疗。在该方法的另一示例中，诸如阀或支架的假体被放置在工作部位内，该工作部位与工作部位远程断开的线引导件相连，并且辅助装置（例如扩张气囊或第二假体）在第一个传送系统被删除之后被引入工作现场。

4. 发明申请

US20060247530A1 Echogenic markers on GI medical devices 审中-公开
标题翻译： GI医疗器械上的生态标志物
公开(公告)号：US20060247530A1
公开(公告)日：2006-11-02
申请号：US11365580
申请日：2006-02-28
申请人： David Hardin , Kenneth Kennedy , Brian Rucker , Gregory Skerven
发明人： David Hardin , Kenneth Kennedy , Brian Rucker , Gregory Skerven
IPC分类号： A61B8/14
CPC分类号： A61B10/04 , A61B1/2736 , A61B8/0833 , A61B8/12 , A61B8/445 , A61B17/221 , A61B17/3478 , A61B2010/0216 , A61B2017/22042 , A61B2017/2212 , A61B2090/062 , A61B2090/3784 , A61B2090/3925
摘要： An endoscopic ultrasound-guided system and method for monitoring the location of a device contained within intraluminal and extraluminal regions of a patient is described. The endoscopic ultrasound-guided system includes a linear echoendoscope, a device, and a wire guide. The device and wire guide contain echogenic surfaces which enable transducers placed at the distal end of the linear echoendoscope to ultrasonically monitor the location of the devices. When the echogenic surface of the device encounters incident ultrasound waves emitted from a series of linear array transducers, a real-time ultrasonic image of the device is generated as the incident ultrasound waves reflect off the echogenic surfaces and propagate back towards the transducers. The surgeon receives the real-time ultrasonic image of the device and then can determine the location of the device within the intraluminal or extraluminal region of the patient. After determining the location of the device, the surgeon can adjust the path of the device to ensure it is guided to the target site.
摘要翻译：描述了内窥镜超声引导系统和用于监测包含在患者的腔内和腔外区域内的装置的位置的方法。内窥镜超声引导系统包括线性回声内窥镜，装置和线引导件。该装置和导线导轨包含回声表面，使得放置在线性回声内窥镜的远端处的换能器能够超声监视装置的位置。当装置的回波表面遇到从一系列线性阵列换能器发射的入射超声波时，随着入射超声波从回波表面反射并向换能器传播，产生该装置的实时超声波图像。外科医生接收设备的实时超声波图像，然后可以确定装置在患者的腔内或管腔内的位置。在确定设备的位置后，外科医生可以调整设备的路径，以确保其被引导到目标位置。

5. 发明申请

US20050070794A1 System for introducing multiple medical devices 审中-公开
标题翻译：引进多种医疗器械的系统
公开(公告)号：US20050070794A1
公开(公告)日：2005-03-31
申请号：US10901561
申请日：2004-07-29
申请人： Stephen Deal , Matthew Carter , Frederick Haller , David Hardin , Kenneth Kennedy , Brian Rucker , Gregory Skerven , David Waller
发明人： Stephen Deal , Matthew Carter , Frederick Haller , David Hardin , Kenneth Kennedy , Brian Rucker , Gregory Skerven , David Waller
IPC分类号： A61B1/01 , A61B1/018 , A61B6/12 , A61B17/22 , A61F2/04 , A61M25/00 , A61M25/06 , A61B6/00
CPC分类号： A61B1/018 , A61B6/12 , A61B17/221 , A61B2017/2212 , A61F2/95 , A61F2002/041 , A61F2002/9511 , A61M25/0029 , A61M25/0662 , A61M25/10 , A61M2025/0183 , A61M2025/0681
摘要： A method and apparatus for introducing a first elongate medical device and short wire guide that are coupled together into a work site and remotely disconnecting them within the work site such that a secondary device comprising a catheter member can be introduced over the wire guide to the work site, and/or a second wire guide can be introduced to the work site via a passageway of the primary access device. A system of indicia, such as radiopaque or viewable markers, permits the operator to monitor the relative alignment of the devices within the work site to determine when uncoupling has occurred. In one example of the method, a wire guide and primary access device (e.g., a sphincterotome) is coupled to the wire guide and introduced via a duodenoscope into the biliary system. After performing a first medical operation, the devices are uncoupled with the wire guide being left within the biliary system such that a secondary access device, such as a balloon, biopsy device, stent delivery catheter, dilator, etc., can be introduced to perform a second medical operation without a traditional over-the-wire exchange being required. In another example of the method, a prosthesis, such as a valve or stent, is placed within the work site coupled to a wire guide which is remotely disconnected within the work site and a secondary device, such as a dilation balloon or second prosthesis, is introduced into the work site after the first delivery system is removed.
摘要翻译：一种用于引入第一细长医疗装置和短线引导件的方法和装置，所述第一细长医疗装置和短导线引导件联接在一起成为工作现场并在工作现场内远程地断开它们，使得包括导管部件的辅助装置可以被引导到导线器上，现场和/或第二导线引导件可以经由主接入设备的通道引入到工作现场。诸如不透射线或可见标记的标记系统允许操作者监视工作现场内的设备的相对对准以确定何时发生解偶联。在该方法的一个示例中，线导向器和主入口装置（例如括约肌切开机）联接到线导引件并经十二指肠镜引入胆道系统。在执行第一次医疗操作之后，将装置与线引导件脱离在胆汁系统内，使得可以引入二次进入装置，例如气囊，活检装置，支架输送导管，扩张器等，以执行不需要传统的线上交换即可进行第二次医疗。在该方法的另一示例中，诸如阀或支架的假体被放置在工作部位内，该工作部位与工作部位远程断开的线引导件相连，并且辅助装置（例如扩张气囊或第二假体）在第一个传送系统被删除之后被引入工作现场。

6. 发明申请

US20070123971A1 Over the endoscope introducer for stents 有权
标题翻译：用于支架的内窥镜导引器
公开(公告)号：US20070123971A1
公开(公告)日：2007-05-31
申请号：US11604406
申请日：2006-11-27
申请人： Kenneth Kennedy , Gregory Skerven
发明人： Kenneth Kennedy , Gregory Skerven
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/044 , A61F2002/9517 , A61F2002/9665
摘要： Over-the-scope stent introducers for detachably engaging at least a portion of the outside of an endoscope insert and for delivering a stent are provided. Embodiments include an inner member having a distal first end portion and a proximal second end portion and openings defining a channel. The inner member includes an outer surface, inner endoscope engaging surface, and stent abutting restraint disposed at the first end portion. Embodiments also include an outer member having a distal section and proximal section having openings defining a passageway sized to slideably receive at least a portion of the inner member, and a stent carrying inner chamber disposed at the distal section passageway and being configured to releasably contain a stent. In alternative embodiments, the inner and outer members are elongated to dispose substantially concentrically over a majority of an endoscope insert.
摘要翻译：提供了用于可拆卸地接合内窥镜插入件的外部的至少一部分并用于输送支架的超范围的支架引入器。实施例包括具有远端第一端部分和近端第二端部部分以及限定通道的开口的内部构件。内部构件包括设置在第一端部处的外表面，内部内窥镜接合表面和支架邻接约束件。实施例还包括外部构件，其具有远侧部分和近端部分，其具有限定通道的开口，所述开口限定为可滑动地容纳内部构件的至少一部分，以及支架内部室，其设置在远端区段通道处并且构造成可释放地容纳支架。在替代实施例中，内部和外部构件是细长的，以大致同心地配置在内窥镜插入件的大部分上。

7. 发明申请

US20050059990A1 System and method for introducing multiple medical devices 有权
标题翻译：引入多种医疗器械的系统和方法
公开(公告)号：US20050059990A1
公开(公告)日：2005-03-17
申请号：US10902438
申请日：2004-07-29
申请人： Juan Ayala , Stephen Deal , Charles Agnew , Gregory Skerven
发明人： Juan Ayala , Stephen Deal , Charles Agnew , Gregory Skerven
IPC分类号： A61B1/01 , A61B1/018 , A61B6/12 , A61B17/22 , A61F2/04 , A61M25/00 , A61M25/06 , A61M29/00
CPC分类号： A61B1/018 , A61B6/12 , A61B17/221 , A61B2017/2212 , A61F2/95 , A61F2002/041 , A61F2002/9511 , A61M25/0029 , A61M25/0662 , A61M25/10 , A61M2025/0183 , A61M2025/0681
摘要： A method and apparatus for introducing a first elongate medical device and short wire guide that are coupled together into a work site and remotely disconnecting them within the work site such that a secondary device comprising a catheter member can be introduced over the wire guide to the work site, and/or a second wire guide can be introduced to the work site via a passageway of the primary access device. A separating member may be provided to remotely separate the wire guide from the elongate medical device. A system of indicia, such as radiopaque or viewable markers, permits the operator to monitor the relative alignment of the devices within the work site to determine when uncoupling has occurred. In one example of the method, a wire guide and primary access device (e.g., a sphincterotome) is coupled to the wire guide and introduced via a duodenoscope into the biliary system. After performing a first medical operation, the devices are uncoupled with the wire guide being left within the biliary system such that a secondary access device, such as a balloon, biopsy device, stent delivery catheter, dilator, etc., can be introduced to perform a second medical operation without a traditional over-the-wire exchange being required. In another example of the method, a prosthesis, such as a valve or stent, is placed within the work site coupled to a wire guide which is remotely disconnected within the work site and a secondary device, such as a dilation balloon or second prosthesis, is introduced into the work site after the first delivery system is removed.
摘要翻译：一种用于引入第一细长医疗装置和短线引导件的方法和装置，所述第一细长医疗装置和短导线引导件联接在一起成为工作现场并在工作现场内远程地断开它们，使得包括导管部件的辅助装置可以被引导到导线器上，现场和/或第二导线引导件可以经由主接入设备的通道引入到工作现场。可以设置分离构件以远程地将电线引导件与细长医疗装置分离。诸如不透射线或可见标记的标记系统允许操作者监视工作现场内的设备的相对对准以确定何时发生解偶联。在该方法的一个示例中，线导向器和主入口装置（例如括约肌切开机）联接到线导引件并经十二指肠镜引入胆道系统。在执行第一次医疗操作之后，将装置与线引导件脱离在胆汁系统内，使得可以引入二次进入装置，例如气囊，活检装置，支架输送导管，扩张器等，以执行不需要传统的线上交换即可进行第二次医疗。在该方法的另一示例中，诸如阀或支架的假体被放置在工作部位内，该工作部位与工作部位远程断开的线引导件相连，并且辅助装置（例如扩张气囊或第二假体）在第一个传送系统被删除之后被引入工作现场。

8. 发明申请

US20080045976A1 SUTURING DEVICE 审中-公开
标题翻译：装备装置
公开(公告)号：US20080045976A1
公开(公告)日：2008-02-21
申请号：US11839753
申请日：2007-08-16
申请人： William Gibbons , Gregory Skerven
发明人： William Gibbons , Gregory Skerven
IPC分类号： A61B17/04
CPC分类号： A61B17/0482 , A61B17/0467 , A61B17/0469 , A61B17/0487 , A61B17/0625 , A61B2017/0454 , A61B2017/0472 , A61B2017/0496
摘要： A suturing device for apposition of tissues is disclosed. The device comprises an introducer having a first port, a second port, and a suture port formed therethrough. First and second needle assemblies are disposed through the first and second ports, respectively. First and second ferrules are removably disposed in the first and second ports, respectively, at a distal end of the introducer. The first and second ferrules are configured to receive the first and second assemblies, respectively, for tissue apposition. A fastener for attaching suture wires is disposed in the suture port at the distal end of the introducer. First and second suture wires are attached to the first and second ferrules, respectively, and extend through the fastener for apposition of tissues.
摘要翻译：公开了一种用于组织组合的缝合装置。该装置包括具有第一端口，第二端口和通过其形成的缝合线端口的导引器。第一和第二针组件分别设置穿过第一和第二端口。第一和第二套圈分别可拆卸地设置在引导器的远端处的第一和第二端口中。第一和第二套圈被配置为分别接收用于组织安置的第一和第二组件。用于连接缝合线的紧固件设置在引导器的远端处的缝合线端口中。第一缝合线和第二缝合线分别附接到第一和第二套圈，并且延伸穿过紧固件用于组织的安置。

9. 发明申请

US20070239284A1 Coiled intragastric member for treating obesity 审中-公开
标题翻译：用于治疗肥胖的盘管胃内成员
公开(公告)号：US20070239284A1
公开(公告)日：2007-10-11
申请号：US11643430
申请日：2006-12-21
申请人： Gregory Skerven , Maximiliano Soetermans , Donagh O'Sullivan
发明人： Gregory Skerven , Maximiliano Soetermans , Donagh O'Sullivan
IPC分类号： A61F2/04
CPC分类号： A61F5/0003 , A61F5/0036 , A61F2002/044
摘要： An apparatus and method comprising at least one intragastric member comprising a curvilinear axis which extends about and along a central axis of an intragastric device or artificial bezoar made of a digestive-resistant or substantially indigestible material that is introduced into the gastric lumen of a mammal for the treatment of obesity. One or more intragastric members are loaded onto an outer delivery tube in a partially compacted first configuration and delivered to an overtube. The overtube includes a proximal end, a distal end and a main lumen configured to receive the intragastric member in the first configuration for delivery to the gastric lumen wherein the intragastric member is expanded to a second configuration.
摘要翻译：一种装置和方法，包括至少一个胃内构件，其包括围绕并沿着胃内装置的中心轴线延伸的曲线轴线，或者由消化不良或基本上难消化的材料制成的人造牛黄被引入到哺乳动物的胃腔中治疗肥胖。将一个或多个胃内部件以部分压实的第一构型装载到外部输送管上并且被输送到外套管。所述外套管包括近端，远端和主腔，所述主腔经配置以在所述第一构造中接纳所述胃内构件以输送至胃腔，其中所述胃内构件被扩张至第二构型。

10. 发明申请

US20060235271A1 Endoscopic apparatus having an improved elevator 有权
标题翻译：内窥镜装置具有改进的电梯
公开(公告)号：US20060235271A1
公开(公告)日：2006-10-19
申请号：US11404554
申请日：2006-04-14
申请人： Matthew Carter , Gregory Skerven
发明人： Matthew Carter , Gregory Skerven
IPC分类号： A61B1/00
CPC分类号： A61B1/01 , A61B1/00087 , A61B1/00098 , A61B1/018 , A61B17/29 , A61B2017/00296 , A61B2017/003
摘要： A grasping apparatus for use with an elevator of an endoscope having enhanced grasping features for grasping an elongate medical device is disclosed. The apparatus comprises a body comprising a grasping surface and an opening formed through the grasping surface to receive the elevator. The opening of the body is configured to be disposed about the elevator of the endoscope. The grasping surface is configured to be disposed on the elevator for grasping of the elongate medical device.
摘要翻译：公开了一种与用于抓握细长医疗装置的具有增强的抓握特征的内窥镜用电梯一起使用的把持装置。该装置包括主体，该主体包括抓握表面和通过抓握表面形成以接收电梯的开口。身体的开口构造成围绕内窥镜的电梯设置。抓握表面被配置为设置在电梯上用于抓住细长医疗装置。

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