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1. 发明申请

US20070276428A1 Intragastric bag for treating obesity 有权
标题翻译：用于治疗肥胖的胃内袋
公开(公告)号：US20070276428A1
公开(公告)日：2007-11-29
申请号：US11643436
申请日：2006-12-21
申请人： Frederick Haller , John Karpiel , Donagh O'Sullivan , Brian Rucker , Maximiliano Soetermans , William Voorhees
发明人： Frederick Haller , John Karpiel , Donagh O'Sullivan , Brian Rucker , Maximiliano Soetermans , William Voorhees
IPC分类号： A61M29/04
CPC分类号： A61F5/0003 , A61F5/0036
摘要： An apparatus and method comprising at least one intragastric member made of a digestive-resistant or substantially indigestible material that is introduced into a bag located in the gastric lumen of a mammal for the treatment of obesity. One or more intragastric members are loaded into a delivery tube in a partially compacted first configuration and delivered to an overtube. The overtube includes a proximal end, a distal end and a lumen configured to receive the intragastric members in the first configuration for delivery to the bag located in the gastric lumen wherein the intragastric member is expanded to a second configuration. The apparatus further comprises a constraining element engaged with the bag to secure the intragastric member upon delivery into the gastric lumen.
摘要翻译：一种装置和方法，包括至少一个由消化不良或基本上难消化的材料制成的胃内部件，所述胃内部件被引入位于哺乳动物的胃腔中的用于治疗肥胖症的袋中。将一个或多个胃内部件以部分压实的第一构型装载到输送管中并输送到外套管。所述外套管包括近端，远端和构造成在所述第一构造中接收所述胃内构件的内腔，用于输送到位于胃腔内的囊，其中所述胃内构件被扩张至第二构型。所述装置还包括与所述袋接合的约束元件，以在输送到胃管腔中时固定胃内部件。

2. 发明授权

US5295968A Stylet wire assembly 失效
标题翻译：探针线组件
公开(公告)号：US5295968A
公开(公告)日：1994-03-22
申请号：US932321
申请日：1992-08-19
申请人： Mark C. Martel , John Karpiel
发明人： Mark C. Martel , John Karpiel
IPC分类号： A61M25/01 , A61M5/00
CPC分类号： A61M25/0102
摘要： A stylet wire assembly is disclosed which sealingly engages the proximal end of a medical catheter, and allows the unobstructed injection or evacuation of fluids into or from a patient's body through the catheter while the stylet wire is in place therein. The disclosed assembly includes a stylet wire and a housing. The housing has a catheter fluid communication port at its distal end and anchors the stylet wire into its closed proximal end with the stylet wire extending through the catheter fluid communication port at the distal end of the housing. This anchoring is accomplished by means of a plug which has been injection molded about the crimped proximal end of the stylet wire and bonded to the distal end of the remainder of the housing. An external fluid communication port allows for fluid communication into and out of said housing in transverse orientation relative to the axis of said stylet wire within said housing and distally of the anchoring of the stylet wire into the proximal end of the housing. The distal end of the housing sealingly engages the proximal end of a medical catheter in fluid communication between the catheter fluid communication port of the housing and the fluid conduit of the catheter by means of the combined effect of a female threaded portion which advances over the end of the catheter and an inner sealing tubular portion which advances within the fluid conduit of the catheter. A fluid conduit provides fluid communication within the housing between the catheter fluid communication port and the external fluid communication port. Upon removal of the stylet wire assembly, the proximal end of the medical catheter can be connected directly to an infusion/evacuation tube without the need for sealing the second port of the standardly used T-fitting.
摘要翻译：公开了一种针刺线组件，其密封地接合医用导管的近端，并且允许通过导管将流体无阻碍地注入或排出患者身体，同时探针线位于其中。所公开的组件包括探针线和壳体。壳体在其远端具有导管流体连通口，并将探针线锚固到其封闭的近端，探针线延伸穿过壳体远端处的导管流体连通口。这种锚固是通过塞子来完成的，塞子已被注射模制在针刺线的卷曲近端上并且结合到壳体的其余部分的远端。外部流体连通端口允许流体连通进入和离开所述壳体的横向方位，相对于所述壳体内的所述探针线的轴线，并且远程地将通孔针线锚定到壳体的近端中。外壳的远端密封地接合医疗导管的近端，其通过外螺纹部分的结合效应在外壳的导管流体连通端口与导管的流体导管之间流体连通以及在导管的流体导管内前进的内密封管状部分。流体导管在壳体内在导管流体连通口和外部流体连通口之间提供流体连通。在取出探针线组件时，医用导管的近端可以直接连接到输液/排气管，而不需要密封标准使用的T形接头的第二端口。

3. 发明申请

US20060030864A1 Catheter with splittable wall shaft and peel tool 有权
公开(公告)号：US20060030864A1
公开(公告)日：2006-02-09
申请号：US11235016
申请日：2005-09-26
申请人： Kenneth Kennedy, , Matthew Carter , Frederick Haller , David Hardin, , David Waller , John Karpiel
发明人： Kenneth Kennedy, , Matthew Carter , Frederick Haller , David Hardin, , David Waller , John Karpiel
IPC分类号： A61F11/00
CPC分类号： A61F2/97 , A61F2/954 , A61F2/962 , A61F2002/065 , A61F2002/9517 , A61M25/0009 , A61M25/0029 , A61M25/0102 , A61M25/0169 , A61M25/0668 , A61M2025/004 , A61M2025/0079 , A61M2025/0183 , A61M2025/09116
摘要： A method and apparatus for uncoupling a wire guide from and elongate medical device comprising a catheter shaft having a wire guide lumen extending there through, wherein the material surrounding the wire guide lumen is selected or adapted to facilitate splittability for removal of the wire guide. The catheter shaft is coextruded and comprises a plurality of materials. The portion of the shaft adjacent the wire guide lumen is formed from a first material and the balance of the shaft is formed from a second material. The first material is selected or adapted to facilitate splittability as compared to the second material. The first material may have a lower durometer than the second material. A peel tool for separating the wire guide from the catheter shaft is also provided.

4. 发明申请

US20080103410A1 Biopsy Collection Device 有权
标题翻译：活检收集装置
公开(公告)号：US20080103410A1
公开(公告)日：2008-05-01
申请号：US11877135
申请日：2007-10-23
申请人： John Karpiel
发明人： John Karpiel
IPC分类号： A61B10/04 , A61B1/018
CPC分类号： A61B10/06 , A61B1/00089 , A61B1/018 , A61B1/2736 , A61B10/0096 , A61B17/3462 , A61B2010/0225 , A61B2010/045 , A61B2017/00296 , A61B2017/3441
摘要： A method and device for removing tissue from a patient during a biopsy procedure utilizing a biopsy collection device are provided. The biopsy collection device includes a body portion configured for attachment to an endoscope and a receptacle portion configured to retain a portion of tissue removed from a target site during the biopsy procedure. The biopsy collection device further includes a passageway configured to receive a biopsy sampling device, such as a pair of forceps, passing through the endoscope to the target site.
摘要翻译：提供了一种在使用活组织检查收集装置的活组织检查过程中从患者去除组织的方法和装置。活组织检查收集装置包括构造成附接到内窥镜的主体部分和被配置为在活检过程期间保留从目标部位移除的一部分组织的容置部分。活组织检查收集装置还包括经配置以接收通过内窥镜到目标部位的活检取样装置，例如一对镊子。

5. 发明申请

US20070260178A1 Apparatus and methods for endoscopic resection of tissue 审中-公开
标题翻译：用于内窥镜切除组织的装置和方法
公开(公告)号：US20070260178A1
公开(公告)日：2007-11-08
申请号：US11786274
申请日：2007-04-11
申请人： Gregory Skerven , John Karpiel
发明人： Gregory Skerven , John Karpiel
IPC分类号： A61M29/00 , A61M5/178
CPC分类号： A61B17/320016 , A61B10/0233 , A61B17/3478 , A61B18/1492 , A61B2017/00269 , A61B2017/320048 , A61M25/0084 , A61M25/104
摘要： The present invention provides apparatus and methods for performing endoscopic mucosal resection and endoscopic submucosal dissection of tissue. In a first embodiment, a catheter having proximal and distal ends and a balloon disposed near the distal end of the catheter is provided. A portion of the distal end of the catheter is configured to be inserted beneath a section of mucosal tissue having a lesion, and the balloon is configured to be inflated to lift the mucosal tissue in an upward direction, thereby facilitating removal of the tissue comprising the lesion. Optionally, a surgeon may advance a needle knife through the catheter to further incise submucosal tissue while the balloon is in the inflated state. If desired, a flushing fluid may be provided to a target site during the procedure.
摘要翻译：本发明提供了用于进行内窥镜粘膜切除和组织内窥镜粘膜下剥离的装置和方法。在第一实施例中，提供具有近端和远端的导管和设置在导管的远端附近的球囊。导管的远端的一部分被配置为插入具有病变部分的粘膜组织的下面，并且气囊被构造成膨胀以沿向上的方向抬起粘膜组织，从而有助于移除包括病变。任选地，外科医生可以使针刀推进穿过导管，以在气囊处于充气状态时进一步切割粘膜下组织。如果需要，可以在程序期间将冲洗流体提供给目标部位。

6. 发明申请

US20070010867A1 Single peel stent introducer apparatus 有权
标题翻译：单皮支架引导器设备
公开(公告)号：US20070010867A1
公开(公告)日：2007-01-11
申请号：US11454607
申请日：2006-06-16
申请人： Mathew Carter , Victor Clark , John Karpiel , Gregory Skerven
发明人： Mathew Carter , Victor Clark , John Karpiel , Gregory Skerven
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9517
摘要： A stent introducer apparatus includes a handle having a housing and a rotatable reel. An inner stent carrier having a proximal end and a distal end is provided, with the proximal end being connected to the housing of the handle. An outer sheath movably disposed about the inner stent carrier and having a proximal end and a distal end is provided, with the proximal end being connected to the reel of the handle. Rotation of the reel relative to the housing peels the outer sheath away from the inner stent carrier so as to move the outer sheath proximally relative to the inner stent carrier, thereby exposing the distal end of the inner stent carrier. The inner stent carrier has a stent carrying portion at its distal end to carry a stent that is deployed when the distal end of the inner stent carrier is exposed.
摘要翻译：支架引入装置包括具有壳体和可旋转卷轴的把手。提供具有近端和远端的内部支架载体，其中近端连接到手柄的外壳。提供了可移动地围绕内部支架托架设置并且具有近端和远端的外护套，其近端连接到手柄的卷轴。卷轴相对于壳体的旋转将外护套远离内支架托架剥离，以便相对于内支架托架向外侧移动外护套，从而暴露内支架托架的远端。内部支架载体在其远端具有支架承载部分，以承载当内部支架载体的远端暴露时展开的支架。

7. 发明授权

US5320602A Peel-away endoscopic retrograde cholangio pancreatography catheter and a method for using the same 失效
标题翻译：剥离内窥镜逆行胆管胰腺造影导管及其使用方法
公开(公告)号：US5320602A
公开(公告)日：1994-06-14
申请号：US61854
申请日：1993-05-14
申请人： John Karpiel
发明人： John Karpiel
IPC分类号： A61M25/01 , A61M25/00 , A61M25/06 , A61M25/08 , A61M29/00
CPC分类号： A61M25/007 , A61M25/0668 , A61M2025/0096 , A61M2202/0403
摘要： A peel-away endoscopic retrograde cholangio pancreatography catheter and a method for using the same is provided. An endoscope having a passage therethrough is introduced into the mouth of a patient and is guided through the patent's gastroentral tract until an opening at the distal end of the endoscope is in close proximity with the papilla of vater leading to the common bile and pancreatic ducts. A peel-away ERCP catheter is provided which may be guided through the lumen of the endoscope until the distal tip of the catheter emerges from the opening at the distal end of the endoscope. The distal end of the catheter may be guided through the sphincter of oddi and into the common bile or pancreatic duct. A radiopaque dye may be injected through the catheter, into the duct. Additionally, a guide wire may be guided into the common bile or pancreatic duct through the catheter. Thereafter, the catheter may be easily removed without disturbing the placement of the guide wire by pulling on knobs attached to tabs at the proximal end of the catheter while the proximal end of the guide wire is held in place. The force applied to the catheter tabs causes the catheter to split longitudinally along two longitudinal grooves cut into the body of the catheter. Thus, the catheter peels-away from the guide wire without displacing the guide wire. Simultaneously, the pulling force on the tabs splits the catheter away from the guide wire while pulling the catheter up the guide wire. Additionally, a biliary stent can be pushed into the duct using a second peel-away catheter which may then be removed in accordance with the method of the present invention.
摘要翻译：提供了一种剥离内窥镜逆行胆管胰腺造影导管及其使用方法。具有穿过其中的通道的内窥镜被引入患者的口中并被引导通过专利胃肠道，直到内窥镜的远端处的开口与通过胆汁和胰管的血浆的乳头紧密接近。提供剥离的ERCP导管，其可以被引导通过内窥镜的内腔，直到导管的远端从内窥镜的远端的开口处露出。导管的远端可引导通过括号括约肌并进入胆总管或胰管。不透射线的染料可以通过导管注入管道。另外，引导线可以通过导管被引导到胆总管或胰管中。此后，可以容易地移除导管，而不会通过拉动附接到导管的近端处的突出部的突出部的棘轮，同时引导线的近端保持在适当位置而不干扰引导线的放置。施加到导管片的力导致导管沿着切入导管主体的两个纵向凹槽纵向分开。因此，导管剥离导丝而不移动导丝。同时，在将导管向上拉出导丝的同时，翼片上的拉力将导管分离出导丝。此外，胆管支架可以使用第二剥离导管推入管道，然后可以根据本发明的方法将其取出。

8. 发明申请

US20080015574A1 Electrosurgical cutting device 审中-公开
标题翻译：电外切切割装置
公开(公告)号：US20080015574A1
公开(公告)日：2008-01-17
申请号：US11729402
申请日：2007-03-28
申请人： John Karpiel
发明人： John Karpiel
IPC分类号： A61B18/14
CPC分类号： A61B18/1492
摘要： A method and device for incising tissue from the gastrointestinal tract are described. The device is an electrosurgical cutting device. The electrosurgical cutting device includes a catheter and multiple electrically conductive cutting wires extending through a lumen of the catheter. The wires are movable between a retracted position and an extended cutting position. The wires form a divergent configuration in the extended cutting position. The electrosurgical cutting device may be loaded into an endoscope, which is then maneuvered to the target tissue site to be incised. Manipulating a handle assembly extends the wires into a divergent cutting configuration. Electrical current is applied causing the wires to incise tissue from the target site.
摘要翻译：描述了从胃肠道切除组织的方法和装置。该装置是电外科切割装置。电外科切割装置包括导管和延伸穿过导管内腔的多个导电切割线。电线可以在缩回位置和延伸的切割位置之间移动。导线在延伸的切割位置形成发散构造。电外科切割装置可以装载到内窥镜中，然后将其操纵到要切割的目标组织部位。操纵手柄组件将电线延伸成发散的切割配置。施加电流导致电线从目标部位切开组织。

9. 发明授权

US07314481B2 Stent introducer apparatus 有权
标题翻译：支架引导装置
公开(公告)号：US07314481B2
公开(公告)日：2008-01-01
申请号：US10449730
申请日：2003-05-30
申请人： John Karpiel
发明人： John Karpiel
IPC分类号： A61F2/04
CPC分类号： A61F2/95 , A61F2/97 , A61F2002/9517
摘要： A stent introducer apparatus includes a handle with a proximal end and a distal end and having a portion that is coaxially slidable from the distal end to the proximal end and vice versa. A catheter having a proximal end and a distal end is provided with a pair of open end slits each of which defines a tab that is connected to the slidable portion of the handle. A guide wire is disposed within the catheter and has a proximal end and a distal end such that when the slidable portion of the handle is moved from the distal end to the proximal end, the distal end of the guide wire is exposed. The guide wire has a stent carrying portion at its distal end to carry a stent that is deployed when the distal end of the guide wire is exposed.
摘要翻译：支架导引器装置包括具有近端和远端的手柄，并且具有从远端到近端同轴滑动的部分，反之亦然。具有近端和远端的导管设置有一对开口狭缝，每个开口端限定了连接到手柄的可滑动部分的突出部。引导线布置在导管内并且具有近端和远端，使得当手柄的可滑动部分从远端移动到近端时，引导线的远端被暴露。导线在其远端具有支架承载部分，以承载当导线的远端暴露时展开的支架。

10. 发明申请

US20070282355A1 Release mechanisms for a clip device 审中-公开
标题翻译：剪辑设备的释放机制
公开(公告)号：US20070282355A1
公开(公告)日：2007-12-06
申请号：US11807827
申请日：2007-05-30
申请人： Hilbert Brown , Steve Chen , Caroline Gayzik , Richard Ducharme , John Karpiel , Kathryn Kornrumpf , Vihar Surti
发明人： Hilbert Brown , Steve Chen , Caroline Gayzik , Richard Ducharme , John Karpiel , Kathryn Kornrumpf , Vihar Surti
IPC分类号： A61B17/08
CPC分类号： A61B17/122 , A61B17/0643 , A61B17/1285 , A61B2017/0053 , A61B2017/0641 , A61B2090/033
摘要： A clip device for hemostasis includes a clip having a proximal end portion and at least two arm portions extending from the proximal end portion and provided with a tendency to open. A sliding ring is provided for closing the arm portions of the clip. A first retainer is attached to the clip, and the first retainer is configured to be releasably secured to a second retainer that may be attached to an operating wire or a torque cable. In operation, the clip device is advanced to a target site in a body cavity. An outer sheath is retracted to expose the clip, causing the arms to open. An inner sheath is advanced distally, causing the sliding ring to advance distally to close the arms of the clip. Stop elements may be disposed on the clip to ensure that he sliding ring is not advanced distally over the clip. Then, the first retainer is disengaged from the second retainer. Various mechanisms are disclosed to permit the first and second retainers to disengage from one another. The first retainer, attached to the clip, is left inside the patient's body cavity, while the second retainer is removed from the patient.
摘要翻译：用于止血的夹子装置包括具有近端部分和从近端部分延伸并且具有打开倾向的至少两个臂部分的夹子。提供一个用于封闭夹子的臂部分的滑动环。第一保持器附接到夹子，并且第一保持器构造成可释放地固定到可附接到操作线或扭矩电缆的第二保持器。在操作中，夹具装置前进到体腔中的目标部位。外护套缩回以露出夹子，导致臂打开。内护套向远侧推进，导致滑环向远侧前进以闭合夹子的臂。止动元件可以设置在夹子上以确保他的滑环在夹子上不向远端推进。然后，第一保持器与第二保持器脱离接合。公开了允许第一和第二保持器彼此脱离的各种机构。附接到夹子上的第一保持器留在患者的体腔内，而第二个保持器从病人身上取下。

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