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1. 发明授权

US06293938B1 Photo-refractive keratectomy 失效
$Photo-refractive keratectomy$
标题翻译：光折射角膜切除术
公开(公告)号：US06293938B1
公开(公告)日：2001-09-25
申请号：US08695115
申请日：1996-08-08
申请人： David F. Muller , Mike D'Agati , Marc Friedman , Troy Harmon , Peter Klopotek , Alex Sacharoff , Evan Sherr
发明人： David F. Muller , Mike D'Agati , Marc Friedman , Troy Harmon , Peter Klopotek , Alex Sacharoff , Evan Sherr
IPC分类号： A61F908
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00872
摘要： The invention features improvements in PRK procedures that relate to preventing non-uniform removal of material from the corneal surface. It has been realized that photoablation by-products resulting during the PRK procedure can affect the accuracy and the predictability of the procedure. Under certain conditions, the plume of photoablation by-products that have left the corneal surface can non-uniformly redeposit onto the ablation area and thus affect the uniformity of subsequent material removal. The plume of photoablation by-products, in the space above the corneal surface, can also non-uniformly affect the escape of further photoablation products from the surface. In addition to the plume effects, it has been realized that the hydration level of the corneal tissue during the PRK procedure can vary over the ablation area and likewise non-uniformly affect the PRK procedure.
摘要翻译：本发明的特征在于PRK程序的改进涉及防止材料从角膜表面的不均匀去除。已经意识到，在PRK过程中产生的光消除副产物可能影响程序的准确性和可预测性。在某些条件下，离开角膜表面的光消融副产物的羽毛可能不均匀地再沉积到消融区域上，从而影响随后的材料去除的均匀性。在角膜表面以上的空间中，光消融副产物的羽毛也可以不均匀地影响进一步的光消化产物从表面的逸出。除了羽流效应之外，已经认识到在PRK程序期间角膜组织的水合水平可以在消融区域上变化，并且同样不均匀地影响PRK程序。

2. 发明授权

US08231673B2 Non-invasive power adjustable intraocular lens 有权
标题翻译：无创功率可调眼内镜
公开(公告)号：US08231673B2
公开(公告)日：2012-07-31
申请号：US12434237
申请日：2009-05-01
申请人： Alex Sacharoff , Mutlu Karakelle
发明人： Alex Sacharoff , Mutlu Karakelle
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2/1618 , A61F9/008 , A61F9/00834 , A61F2009/0087 , A61F2009/0088 , A61F2250/001 , A61F2250/0071
摘要： An improved multifocal design for an ocular implant is provided. This ocular implant includes an intraocular lens (IOL) and a number of haptics. The IOL passes optical energy. A microstructure within the IOL places the IOL under tension. The microstructure is operable to be broken in a controlled manner to release tension in the IOL and reshape the IOL. This may be done at any time post operatively and in conjunction with wavefront aberrometry to provide improved results. The haptics mechanically couple to the IOL in order to position and secure the IOL within the eye.
摘要翻译：提供了用于眼部植入物的改进的多焦点设计。这种眼部植入物包括眼内透镜（IOL）和许多触觉。 IOL传递光能。 IOL中的微结构使IOL处于张力下。微结构可操作地以受控的方式破碎以释放IOL中的张力并重塑IOL。这可以在手术后的任何时间并结合波前像差测量来完成，以提供改进的结果。触觉件机械地耦合到IOL以便将眼睛中的IOL定位和固定。

3. 发明申请

US20090281620A1 NON-INVASIVE POWER ADJUSTABLE INTRAOCULAR LENS 有权
标题翻译：非入射功率可调节内窥镜
公开(公告)号：US20090281620A1
公开(公告)日：2009-11-12
申请号：US12434237
申请日：2009-05-01
申请人： Alex Sacharoff , Mutlu Karakelle
发明人： Alex Sacharoff , Mutlu Karakelle
IPC分类号： A61F2/16 , A61F2/14
CPC分类号： A61F2/1635 , A61F2/1618 , A61F9/008 , A61F9/00834 , A61F2009/0087 , A61F2009/0088 , A61F2250/001 , A61F2250/0071
摘要： An improved multifocal design for an ocular implant is provided. This ocular implant includes an intraocular lens (IOL) and a number of haptics. The IOL passes optical energy. A microstructure within the IOL places the IOL under tension. The microstructure is operable to be broken in a controlled manner to release tension in the IOL and reshape the IOL. This may be done at any time post operatively and in conjunction with wavefront aberrometry to provide improved results. The haptics mechanically couple to the IOL in order to position and secure the IOL within the eye.
摘要翻译：提供了用于眼部植入物的改进的多焦点设计。这种眼部植入物包括眼内透镜（IOL）和许多触觉。 IOL传递光能。 IOL中的微结构使IOL处于张力下。微结构可操作地以受控的方式破碎以释放IOL中的张力并重塑IOL。这可以在手术后的任何时间并结合波前像差测量来完成，以提供改进的结果。触觉件机械地耦合到IOL以便将眼睛中的IOL定位和固定。

4. 发明申请

US20080221559A1 Calibration and Quality Assurance System For Use With Ophthalmic Surgical Devices and Associated Methods 审中-公开
标题翻译：用于眼科手术装置的校准和质量保证体系及相关方法
公开(公告)号：US20080221559A1
公开(公告)日：2008-09-11
申请号：US11682628
申请日：2007-03-06
申请人： Phuoc Khanh Nguyen , Alex Sacharoff , James Strobel , Sebastian Spoerlein
发明人： Phuoc Khanh Nguyen , Alex Sacharoff , James Strobel , Sebastian Spoerlein
IPC分类号： A61F9/008
CPC分类号： G01J1/4257 , A61F9/008 , A61F9/00814 , A61F2009/00855 , A61F2009/00897
摘要： A method for determining a peak fluence of an excimer laser includes scanning an excimer laser beam in a predetermined pattern on a film. The film can include a polymer layer atop a substrate including an upper layer having a first characteristic and a lower layer having a second characteristic detectably distinct from the first characteristic. The predetermined pattern includes a plurality of discrete points receiving incrementally greater numbers of pulses, at least one point receiving a sufficient number of pulses to penetrate through the polymer layer and the upper layer. A breakthrough point is detected at which a smallest number of pulses was sufficient to penetrate through the polymer layer and the upper layer, thereby exposing the lower layer to a detection of the second characteristic. A peak fluence of the excimer laser can then be determined from the number of pulses received at the detected breakthrough point.
摘要翻译：用于确定准分子激光器的峰值注量的方法包括以预定图案在膜上扫描准分子激光束。膜可以包括在包括具有第一特征的上层的基底上的聚合物层和具有可检测地不同于第一特性的第二特征的下层。预定图案包括多个离散点，其接收递增更大数量的脉冲，至少一个点接收足够数量的脉冲以穿透聚合物层和上层。检测到最小数量的脉冲足以穿透聚合物层和上层的突破点，从而使下层暴露于第二特性的检测。然后可以从检测到的穿透点处接收的脉冲数来确定准分子激光器的峰值注量。

5. 发明申请

US20070142826A1 Modification of laser ablation treatment prescription using corneal mechanical properties and associated methods 审中-公开
标题翻译：使用角膜机械性能和相关方法修改激光烧蚀治疗处方
公开(公告)号：US20070142826A1
公开(公告)日：2007-06-21
申请号：US11303465
申请日：2005-12-16
申请人： Alex Sacharoff
发明人： Alex Sacharoff
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00806 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088
摘要： A method of the present invention is directed to improving an outcome of a surgical procedure on a patient cornea. The method includes the steps of measuring a mechanical parameter of a cornea of an eye and determining a laser-surgery prescription for the cornea to improve a visual parameter therefor. The prescription is then adjusted based upon the measured mechanical parameter of the cornea.
摘要翻译：本发明的方法涉及改善对患者角膜的外科手术的结果。该方法包括以下步骤：测量眼睛的角膜的机械参数并确定角膜的激光手术处方以改善其视觉参数。然后根据测量的角膜的机械参数调整处方。

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