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1. 发明申请

US20080221559A1 Calibration and Quality Assurance System For Use With Ophthalmic Surgical Devices and Associated Methods 审中-公开
标题翻译：用于眼科手术装置的校准和质量保证体系及相关方法
公开(公告)号：US20080221559A1
公开(公告)日：2008-09-11
申请号：US11682628
申请日：2007-03-06
申请人： Phuoc Khanh Nguyen , Alex Sacharoff , James Strobel , Sebastian Spoerlein
发明人： Phuoc Khanh Nguyen , Alex Sacharoff , James Strobel , Sebastian Spoerlein
IPC分类号： A61F9/008
CPC分类号： G01J1/4257 , A61F9/008 , A61F9/00814 , A61F2009/00855 , A61F2009/00897
摘要： A method for determining a peak fluence of an excimer laser includes scanning an excimer laser beam in a predetermined pattern on a film. The film can include a polymer layer atop a substrate including an upper layer having a first characteristic and a lower layer having a second characteristic detectably distinct from the first characteristic. The predetermined pattern includes a plurality of discrete points receiving incrementally greater numbers of pulses, at least one point receiving a sufficient number of pulses to penetrate through the polymer layer and the upper layer. A breakthrough point is detected at which a smallest number of pulses was sufficient to penetrate through the polymer layer and the upper layer, thereby exposing the lower layer to a detection of the second characteristic. A peak fluence of the excimer laser can then be determined from the number of pulses received at the detected breakthrough point.
摘要翻译：用于确定准分子激光器的峰值注量的方法包括以预定图案在膜上扫描准分子激光束。膜可以包括在包括具有第一特征的上层的基底上的聚合物层和具有可检测地不同于第一特性的第二特征的下层。预定图案包括多个离散点，其接收递增更大数量的脉冲，至少一个点接收足够数量的脉冲以穿透聚合物层和上层。检测到最小数量的脉冲足以穿透聚合物层和上层的突破点，从而使下层暴露于第二特性的检测。然后可以从检测到的穿透点处接收的脉冲数来确定准分子激光器的峰值注量。

2. 发明授权

US06712809B2 Eye positioning system and method 有权
标题翻译：眼睛定位系统和方法
公开(公告)号：US06712809B2
公开(公告)日：2004-03-30
申请号：US10097639
申请日：2002-03-14
申请人： Haizhang Li , Phuoc Khanh Nguyen
发明人： Haizhang Li , Phuoc Khanh Nguyen
IPC分类号： A61B1818
CPC分类号： A61F9/008 , A61F9/00802 , A61F2009/00855
摘要： A system for positioning an eye for laser surgery includes a first and a second radiation generator positioned, respectively, to emit a first line and a second line orthogonal to the first line, the line generators positioned in a predetermined relation to a laser surgical system. A position of the eye is adjustable along an axis that is substantially perpendicular to the lines to achieve a positioning wherein the lines form a cross. The location of the cross is a preferred position for the eye relative to the laser surgical system for the laser surgery. Another embodiment comprises a first and a second spot generator positioned to project a first and a second spot onto an eye adjacent the clear cornea, between the clear cornea and the scleral rim. The eye position is adjustable for achieving a positioning wherein the spots are substantially vertically aligned.
摘要翻译：用于定位用于激光手术的眼睛的系统包括分别定位成发射与第一线正交的第一线和第二线的第一和第二辐射发生器，线发生器以与激光手术系统预定的关系定位。眼睛的位置沿着基本上垂直于线的轴线是可调节的，以实现定位，其中线形成十字。十字架的位置是眼睛相对于激光手术的激光手术系统的优选位置。另一实施例包括第一和第二点发生器，其定位成将第一和第二斑点突出到邻近透明角膜的眼睛之间，透明角膜和巩膜边缘之间。眼睛位置是可调节的，以实现定位，其中斑点基本上垂直对准。

3. 发明申请

US20080144038A1 PERFORMANCE AND ACCURACY ASSESSMENT SYSTEM FOR REFRACTIVE LASER SYSTEMS AND ASSOCIATED METHODS 审中-公开
标题翻译：折射激光系统的性能和精度评估系统及相关方法
公开(公告)号：US20080144038A1
公开(公告)日：2008-06-19
申请号：US11612721
申请日：2006-12-19
申请人： Richard Alan LeBlanc , Martin Sensiper , Phuoc Khanh Nguyen
发明人： Richard Alan LeBlanc , Martin Sensiper , Phuoc Khanh Nguyen
IPC分类号： G01N21/55
CPC分类号： A61F9/008 , A61F9/00814 , A61F2009/00855 , A61F2009/00872
摘要： A method for assessing a performance of a laser system for use in corneal ablation is provided that includes directing a beam of laser shots onto a fluorescent indicator. The indicator is adapted to emit a first wavelength of light different from a second wavelength of light impinging thereon. The directing step is performed in a plane of a cornea of an eye desired to be ablated and also onto a cornea positioned at the corneal plane. Light reflected from the indicator is detected, and a difference between a detected light pattern from the camera and a predetermined ablation pattern desired to be made on the cornea is calculated. The predetermined pattern is then corrected to compensate for the calculated difference.
摘要翻译：提供了一种用于评估用于角膜消融的激光系统的性能的方法，其包括将激光束射束引导到荧光指示器上。指示器适于发射不同于入射到其上的第二波长的光的第一波长的光。引导步骤在希望被消融的眼睛的角膜的平面中进行，并且还在位于角膜平面上的角膜上进行。检测从指示器反射的光，并且计算来自照相机的检测光图案和期望在角膜上进行的预定消融图案之间的差异。然后校正预定图案以补偿计算出的差。

4. 发明申请

US20060158639A1 Eye tracker and pupil characteristic measurement system and associated methods 审中-公开
标题翻译：眼动仪和瞳孔特征测量系统及相关方法
公开(公告)号：US20060158639A1
公开(公告)日：2006-07-20
申请号：US11252191
申请日：2005-10-17
申请人： John Campin , Young Kwon , Phuoc Khanh Nguyen , Haizhang Li , Gary Gray
发明人： John Campin , Young Kwon , Phuoc Khanh Nguyen , Haizhang Li , Gary Gray
IPC分类号： G01P3/36 , A61B18/18
CPC分类号： A61F9/008 , A61F9/00804 , A61F2009/00846 , A61F2009/00872 , A61F2009/00897
摘要： Systems and methods for tracking eye movement includes directing an incident light beam onto each facet of a pyramidal prism to produce a plurality of beams that form a plurality of light spots, at least two of the light spots having different diameters. The prism is translatable to effect a change in spacing of the light spots. Intensities of light reflected from the light spots is used to retain the light spots upon a pupil/iris boundary. A relative intensity of the spots indicates a change in pupil size. A second light spot positioned on a predetermined eye sector can also be used to calculate a pupil characteristic and an environmental effect on light received from the eye.
摘要翻译：用于跟踪眼睛运动的系统和方法包括将入射光束引导到锥体棱镜的每个小面上以产生形成多个光斑的多个光束，至少两个具有不同直径的光点。棱镜可以平移以实现光斑间距的变化。使用从光点反射的光的强度来将光点保持在瞳孔/虹膜边界上。斑点的相对强度表示瞳孔大小的变化。位于预定眼部的第二光点也可用于计算从眼睛接收的光的光瞳特性和对环境的影响。

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