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1. 发明申请

US20070255217A1 TEXTURED POLYMER COATED GUIDE WIRE AND METHOD OF MANUFACTURE 审中-公开
标题翻译：纹理聚合物涂层指导线和制造方法
公开(公告)号：US20070255217A1
公开(公告)日：2007-11-01
申请号：US11762617
申请日：2007-06-13
申请人： David Burkett , Kevin Britton , Ryan Grandfield , Peter D'Aquanni , David Wrolstad , Edwin Mahieu , Wayne Cornish , Mark Richardson
发明人： David Burkett , Kevin Britton , Ryan Grandfield , Peter D'Aquanni , David Wrolstad , Edwin Mahieu , Wayne Cornish , Mark Richardson
IPC分类号： A61M5/178
CPC分类号： A61M25/09 , A61B17/12145 , A61F2/95 , A61F2/958 , A61M25/0043 , A61M2025/006 , A61M2025/0062 , A61M2025/09108 , A61M2025/09133 , B29C48/05 , B29C48/12 , B29C48/155
摘要： A guide wire for advancing a medical device such as a catheter through a patient's body lumen which has an elongated core with proximal and distal core section, a flexible tubular member such as a coil on the distal end. The wire core includes surface textures that are translated into the overlying coating. Alternatively, the coating has its own surface texture. The surface textures include randomly or non-randomly spaced bumps, divots, ridges, helical grooves, longitudinal grooves, undulations, etc.
摘要翻译：一种用于使诸如导管的医疗装置通过患者体腔前进的导丝，所述导管具有具有近端和远侧芯部的细长芯，在远端上具有诸如线圈的柔性管状构件。线芯包括被翻译成上覆涂层的表面纹理。或者，涂层具有其自己的表面纹理。表面纹理包括随机或非随机间隔的凸块，凸纹，凸脊，螺旋槽，纵向凹槽，起伏等。

2. 发明申请

US20070123930A1 Embolic filtering devices 审中-公开
标题翻译：栓塞过滤装置
公开(公告)号：US20070123930A1
公开(公告)日：2007-05-31
申请号：US11652167
申请日：2007-01-11
申请人： Scott Huter , John Papp , Douglas Gesswein , Wayne Cornish , Peter D'Aquanni , Thomas Tokarchik , Andy Denison , Kevin Magrini , Benjamin Huter , Charles Peterson , William Boyle , Mark Richardson , Ryan Grandfield , Kathern Lind
发明人： Scott Huter , John Papp , Douglas Gesswein , Wayne Cornish , Peter D'Aquanni , Thomas Tokarchik , Andy Denison , Kevin Magrini , Benjamin Huter , Charles Peterson , William Boyle , Mark Richardson , Ryan Grandfield , Kathern Lind
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： An expandable frame for an embolic filtering device used to capture embolic debris in a body vessel includes a first half frame having a first control arm connected to a second control arm by a partial loop and a second half frame having a first control arm connected to a second control arm by a partial loop. The partial loops cooperatively form a composite loop for attachment of a filtering element which will expand in the body vessel to capture embolic debris entrained in the fluid of the vessel. The expandable frame and filtering element can be mounted on a filter support structure, such as a coiled wire, and mounted on a guide wire. The expandable frames includes an articulation region which helps to distribute the strain which can be developed when the frame moves between an expanded and deployed position. The expandable frame may include further strain distributing bends which help distribute strain and increase the bendability of the frame.
摘要翻译：用于捕获身体血管中的栓塞碎片的栓塞过滤装置的可膨胀框架包括：第一半框架，具有通过部分回路连接到第二控制臂的第一控制臂，以及具有连接到第二控制臂的第二控制臂的第二半框架第二控制臂通过部分回路。部分回路协同地形成用于附接过滤元件的复合回路，该过滤元件将在体内容器中膨胀以捕获携带在血管流体中的栓塞碎片。可膨胀框架和过滤元件可以安装在诸如线圈的过滤器支撑结构上，并且安装在导丝上。可扩展框架包括铰接区域，其有助于分布当框架在展开位置和展开位置之间移动时可展开的应变。可扩展框架可以包括进一步的应变分布弯曲，其有助于分布应变并增加框架的可弯曲性。

3. 发明申请

US20070249964A1 POLYMER COATED GUIDE WIRE 有权
标题翻译：聚合物涂层指导线
公开(公告)号：US20070249964A1
公开(公告)日：2007-10-25
申请号：US11768794
申请日：2007-06-26
申请人： Mark Richardson , David Anderson , Emmanuel Biagtan , Lawrence Brennan , David Burkett , Wayne Cornish , Robert Esselstein , James Jacobs , Marc Jalisi , Daryush Mirzaee , Olin Palmer , John Schreiner , Kent Stalker
发明人： Mark Richardson , David Anderson , Emmanuel Biagtan , Lawrence Brennan , David Burkett , Wayne Cornish , Robert Esselstein , James Jacobs , Marc Jalisi , Daryush Mirzaee , Olin Palmer , John Schreiner , Kent Stalker
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

4. 发明授权

US10267609B1 Cartridge reloading machine and components 有权
公开(公告)号：US10267609B1
公开(公告)日：2019-04-23
申请号：US15894914
申请日：2018-02-12
申请人： Mark Richardson
发明人： Mark Richardson , Ralph Richardson
IPC分类号： F42B33/00
摘要： This disclosure an improved progressive shell reloader machine with improved components to reduce friction and jarring, thereby reducing powder losses during the reloading process, components including a smooth ring indexer, a gripping shellplate, and an antifriction camming pin. Additional improved components allow easy halting of primer and shell casing feed, facilitating troubleshooting, components including a positionable and reversible case insert slide block and a slide back primer cam.

5. 发明授权

US09386069B2 Media exposure data collection and security 有权
标题翻译：媒体曝光数据收集和安全
公开(公告)号：US09386069B2
公开(公告)日：2016-07-05
申请号：US13338479
申请日：2011-12-28
申请人： John Stavropoulos , Anand Jain , Wendell Lynch , Vladimir Kuznetsov , Jack Crystal , Jason Bolles , William John McKenna , David Gish , Mark Richardson , Alan Neuhauser
发明人： John Stavropoulos , Anand Jain , Wendell Lynch , Vladimir Kuznetsov , Jack Crystal , Jason Bolles , William John McKenna , David Gish , Mark Richardson , Alan Neuhauser
IPC分类号： G06F15/16 , H04L29/08 , H04L29/06
CPC分类号： H04L67/02 , H04L63/0428 , H04L63/08
摘要： Systems and methods are disclosed for securely transferring research data relating to media exposure data, such as radio, television, streaming media and the Internet. A plurality of portable computing devices seek and bond to a collector via Bluetooth in a specific area, such as a household. The collector authenticates itself with each of the portable computing devices and vice versa where the collector arranges a secure research data transfer session with each respective device using exchanged authentication files. As each secure session is made, each portable computing device transmits stored research data during the session.
摘要翻译：公开了用于安全地传送与媒体曝光数据相关的研究数据（诸如无线电，电视，流媒体和因特网）的系统和方法。多个便携式计算设备通过蓝牙在诸如家庭的特定区域中寻找并结合到收集器。集线器对每个便携式计算设备进行认证，反之亦然，其中收集器使用交换的认证文件与每个相应的设备安排研究数据传输会话。随着每个安全会话的进行，每个便携式计算设备在会话期间发送存储的研究数据。

6. 发明授权

US07509172B2 Stabilizing guide wire apparatus for use with implantable device 失效
标题翻译：用于可植入装置的稳定导丝装置
公开(公告)号：US07509172B2
公开(公告)日：2009-03-24
申请号：US10421213
申请日：2003-04-23
申请人： Mark Richardson , David Anderson
发明人： Mark Richardson , David Anderson
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： An apparatus is usable for guiding and stabilizing a body implantable medical device. The apparatus includes a guide wire with an enlarged distal tip. The enlarged distal tip may include a compliant portion to prevent tissue abrasion or perforation. The implantable device includes an open lumen configured to longitudinally advance along the guide wire. A sleeve is disposed over the guide wire and slidably deployable over the enlarged tip of the guide wire. When the implantable device is in final position, the open lumen encompasses at least part of the enlarged tip of the guide wire. The sleeve can be moved over at least part of the enlarged tip and create an interference between the tip and the open lumen, thereby stabilizing the implantable device.
摘要翻译：一种装置可用于引导和稳定身体可植入医疗装置。该装置包括具有放大的远端的引导线。扩大的远侧末端可以包括柔顺部分以防止组织磨损或穿孔。可植入装置包括被构造为沿着导丝纵向前进的开口腔。套筒布置在引导线上并可滑动地布置在引导线的扩大的尖端上。当可植入装置处于最终位置时，开放的内腔包围引导线的扩大末端的至少一部分。套筒可以在扩大的尖端的至少一部分上移动，并在尖端和开放的内腔之间产生干涉，从而稳定可植入装置。

7. 发明授权

US07431570B2 Capillary pumps for vaporization of liquids 有权
标题翻译：用于液体蒸发的毛细管泵
公开(公告)号：US07431570B2
公开(公告)日：2008-10-07
申请号：US10691067
申请日：2003-10-21
申请人： Thomas M. Young , Mark Richardson , Robert A. Lerner , Barry H. Rabin
发明人： Thomas M. Young , Mark Richardson , Robert A. Lerner , Barry H. Rabin
IPC分类号： F04B19/24 , F04F1/18
CPC分类号： F04B19/24 , F04B17/00 , H01M8/04201 , Y10T137/2224
摘要： A capillary pump is provided for producing pressurized and unpressurized vapor emissions from liquid feed. In its simplest form, the capillary pump incorporates a liquid feed intake, a porous vaporization component, and a heat transfer component. Additional components, such as an insulator component, a feed pre-heat component, a liquid feed reservoir and/or delivery system, an integrated or associated heater component, a vapor collection chamber, a heat distribution component, an orifice component and/or vapor release component, may also be associated with or integrated in the improved capillary pumps. Capillary pump arrays are provided, and numerous applications for capillary pumps are disclosed.
摘要翻译：提供毛细管泵用于从液体进料产生加压和非加压蒸气排放。在其最简单的形式中，毛细管泵结合有液体进料口，多孔汽化部件和传热部件。附加部件，例如绝缘体部件，进料预热部件，液体进料储存器和/或输送系统，集成或相关联的加热器部件，蒸气收集室，热分配部件，孔部件和/或蒸汽释放组分也可以与改进的毛细管泵相关联或集成在改进的毛细管泵中。提供了毛细管泵阵列，并且公开了用于毛细管泵的许多应用。

8. 发明授权

US06390993B1 Guidewire having linear change in stiffness 有权
标题翻译：导丝具有刚度线性变化
公开(公告)号：US06390993B1
公开(公告)日：2002-05-21
申请号：US09203140
申请日：1998-12-01
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson
IPC分类号： A61B500
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

9. 发明授权

US6142975A Guidewire having braided wire over drawn tube construction 有权
标题翻译：导线在拉丝管结构上具有编织线
公开(公告)号：US6142975A
公开(公告)日：2000-11-07
申请号：US224453
申请日：1998-12-31
申请人： Marc Mehrzad Jalisi , Mark Richardson , David M. Anderson , Wayne E. Cornish
发明人： Marc Mehrzad Jalisi , Mark Richardson , David M. Anderson , Wayne E. Cornish
IPC分类号： A61M5/178 , A61M25/09 , B23P11/00
CPC分类号： A61M25/09 , B21C1/003 , B21F17/00 , B21F3/04 , C21D7/02 , A61M2025/09175 , C21D2211/001 , C21D2211/008 , C21D2241/01 , C21D9/52 , Y10S29/011 , Y10T29/49908
摘要： An intracorporeal device, preferably a guidewire, and method of making same that has an elongate inner core element with an outer layer of material disposed about the core element. The layer of material can be applied as a braid, strand or smooth layer of material, and is preferably a metal. If the layer of material is applied as a braid or strand, it may be subsequently cold drawn so as to create a smooth layer from the braid or strand. The inner core element may be homogeneous, or may consist of drawn filled tubing with at least two layers of material, preferably biocompatible metals. In this way, the multiple layer distal section of the elongate core can be shaped or ground so as to achieve the desired mechanical properties and provide surfaces for attachment of components that are readily bonded or soldered to.
摘要翻译：一种体内装置，优选导丝，以及其制造方法，其具有细长的内芯元件，该内芯元件具有围绕芯元件设置的外层材料。材料层可以作为编织物，股线或光滑的材料层施加，优选为金属。如果材料层作为编织物或股线施加，则可以随后冷拉以从编织物或股线形成光滑的层。内芯元件可以是均匀的，或者可以由具有至少两层材料，优选生物相容性金属的拉伸填充管组成。以这种方式，细长芯的多层远端部分可以被成形或研磨，以达到期望的机械性能，并提供用于连接容易粘结或焊接的部件的表面。

10. 发明申请

US20150164431A1 ASSESSING SUSCEPTIBILITY TO EPILEPSY AND EPILEPTIC SEIZURES 审中-公开
标题翻译：评估对于癫痫发作和癫痫发作的可能性
公开(公告)号：US20150164431A1
公开(公告)日：2015-06-18
申请号：US14406452
申请日：2013-06-05
申请人： John Robert Terry , Mark Richardson , Oscar Benjamin
发明人： John Robert Terry , Mark Richardson , Oscar Benjamin
IPC分类号： A61B5/00 , G01R33/48 , A61B5/0476
CPC分类号： A61B5/7275 , A61B5/04004 , A61B5/04008 , A61B5/0476 , A61B5/4094 , A61B5/4848 , A61B5/7246 , A61B5/7264 , G01R33/4806 , G16H50/30 , G16H50/50
摘要： Assessing Susceptibility to Epilepsy and Epileptic Seizures A method and system adapted to assist with assessing susceptibility to epilepsy and/or epileptic seizures in a patient receives (202) patient brain data and generates (204) a network model from the received patient brain data. The system further generates (206) synthetic brain activity data in at least some of the nodes of the network model and computes (208) seizure frequency from the synthetic brain activity data by monitoring transitions from non-seizure states to seizures states in at least some of the nodes over time. The system further includes a device (104, 110) configured to use the seizure frequency to compute (210) a likelihood of susceptibility to epilepsy and/or epileptic seizures in the patient, and a device (104, 110) configured to compare (212) the computed likelihood with another likelihood of susceptibility to epilepsy and/or epileptic seizures in order to assess whether the likelihood has increased or decreased. FIG. 2
摘要翻译：评估对癫痫和癫痫发作的敏感性适于协助评估患者对癫痫和/或癫痫发作的易感性的方法和系统接收（202）患者脑数据，并从接收到的患者脑数据生成（204）网络模型。该系统进一步在网络模型的至少一些节点中产生（206）合成脑活动数据，并通过监视至少一些从非癫痫状态到癫痫发作状态的过渡来从合成脑活动数据计算（208）癫痫发作频率的节点。该系统还包括被配置为使用癫痫发作频率来计算（210）对患者的癫痫和/或癫痫发作易感性的可能性的装置（104,110），以及被配置为比较（212））计算的可能性具有对癫痫和/或癫痫发作易感性的另一可能性，以便评估这种可能性是否增加或减少。图。 2

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