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1. 发明授权

US06612999B2 Balloon actuated guide catheter 有权
公开(公告)号：US06612999B2
公开(公告)日：2003-09-02
申请号：US10011084
申请日：2001-12-06
申请人： Lawrence Brennan , Neil Becker
发明人： Lawrence Brennan , Neil Becker
IPC分类号： A61B500
CPC分类号： A61M25/0041 , A61M25/0152 , A61M25/0155
摘要： A guide catheter employs a flexible shaft having a pre-formed bend at a distal end. An inflatable member is disposed on the flexible shaft and encompasses at least part of the pre-formed bend. The flexible shaft contains an inflation lumen in fluid connection with the inflatable member. Inflation of the inflatable member causes a deflection of the distal end of the flexible shaft. The guide catheter includes an inflation mechanism in fluid connection with the inflation lumen for pressurizing and depressurizing the inflation member. A guide catheter according to the present invention is useful for various medical procedures, including providing access to heart vessels for cardiac lead implantation, EP mapping, and angiography/venography.

2. 发明授权

US06450975B1 Ultrasonic transmission guide wire 有权
标题翻译：超声波传输导丝
公开(公告)号：US06450975B1
公开(公告)日：2002-09-17
申请号：US09475521
申请日：1999-12-30
申请人： Lawrence Brennan , Douglas Gesswein , Wayne Cornish , Robert J. Siegel
发明人： Lawrence Brennan , Douglas Gesswein , Wayne Cornish , Robert J. Siegel
IPC分类号： A61B500
CPC分类号： A61B17/22012 , A61B2017/22015 , A61B2017/22018 , A61B2017/320084 , A61B2017/320088 , G10K11/24
摘要： The ultrasonic angioplasty transmission guide wire has regions of reduced cross-sectional diameter to improve flexibility and to compensate for degradation of longitudinal displacement due to acoustic losses along the length of the guide wire. The guide wire has a core of ultrasonic transmission material and an outer jacket surrounding a usable portion of the elongated shaft. The outer jacket is formed of a shrink tubing. At the proximal end are disposed threads configured to connect to a connecting device for an ultrasound transducer. The distal end comprises a smooth ball tip for atraumatic application of ultrasound energy to biological tissue. In one embodiment, the guide wire is formed of stainless steel. In another, the guide wire is formed at least partially of a superelastic metal alloy and in one case is formed at least partially of a shape memory alloy that exhibits superelastic properties when in its martensitic state. In one preferred embodiment, the guide wire is formed of a nickel-titanium alloy.
摘要翻译：超声波血管成形术传输导线具有减小的横截面直径的区域，以改善柔性并补偿由于沿导丝长度的声学损失引起的纵向位移的退化。引导线具有超声波传输材料的芯和围绕细长轴的可用部分的外护套。外套由收缩管形成。在近端处设置有被配置成连接到用于超声换能器的连接装置的螺纹。远端包括用于将生物组织超声能量无创应用的平滑球头。在一个实施例中，导丝由不锈钢形成。另一方面，所述导丝至少部分地由超弹性金属合金形成，并且在一种情况下至少部分地形成在其马氏体状态下表现出超弹性特性的形状记忆合金。在一个优选实施例中，导丝由镍 - 钛合金形成。

3. 发明授权

US1345909A Operating mechanism for pumps 失效
标题翻译：泵的操作机构
公开(公告)号：US1345909A
公开(公告)日：1920-07-06
申请号：US26146518
申请日：1918-11-07
申请人： LAWRENCE BRENNAN
发明人： LAWRENCE BRENNAN
IPC分类号： F04B9/14
CPC分类号： F04B9/14 , Y10T74/1526

4. 发明申请

US20070249964A1 POLYMER COATED GUIDE WIRE 有权
标题翻译：聚合物涂层指导线
公开(公告)号：US20070249964A1
公开(公告)日：2007-10-25
申请号：US11768794
申请日：2007-06-26
申请人： Mark Richardson , David Anderson , Emmanuel Biagtan , Lawrence Brennan , David Burkett , Wayne Cornish , Robert Esselstein , James Jacobs , Marc Jalisi , Daryush Mirzaee , Olin Palmer , John Schreiner , Kent Stalker
发明人： Mark Richardson , David Anderson , Emmanuel Biagtan , Lawrence Brennan , David Burkett , Wayne Cornish , Robert Esselstein , James Jacobs , Marc Jalisi , Daryush Mirzaee , Olin Palmer , John Schreiner , Kent Stalker
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

5. 发明授权

US06695793B2 Guide catheter for placing cardiac lead 失效
标题翻译：导管用于放置心脏铅
公开(公告)号：US06695793B2
公开(公告)日：2004-02-24
申请号：US09918988
申请日：2001-07-31
申请人： Lawrence Brennan , Fozan El-Nounou
发明人： Lawrence Brennan , Fozan El-Nounou
IPC分类号： A61M25088
CPC分类号： A61M25/0662 , A61M25/0069 , A61M25/04 , A61N2001/0585
摘要： An improved guide catheter provides a distal tip with one or more members that assist a surgeon with locating and inserting the guide catheter through the ostium in the wall of the right atrium that leads to the coronary sinus of the heart. The guide catheter is used to implant a cardiac lead so that its electrodes are positioned in the vasculature associated with the left side of the heart.
摘要翻译：改进的引导导管提供具有一个或多个构件的远侧末端，所述一个或多个构件帮助外科医生定位和插入引导导管通过导向心脏冠状窦的右心房壁的口。引导导管用于植入心脏引线，使得其电极位于与心脏左侧相关联的脉管系统中。

6. 发明申请

US20140243084A1 Photo Based Game Development System and Products 审中-公开
标题翻译：基于照片的游戏开发系统和产品
公开(公告)号：US20140243084A1
公开(公告)日：2014-08-28
申请号：US14184516
申请日：2014-02-19
申请人： Lawrence Brennan Davis
发明人： Lawrence Brennan Davis
IPC分类号： A63F13/00
CPC分类号： A63F13/655 , A63F2001/022 , A63F2003/00892
摘要： An entertainment, educational and merchandizing method for creating games through computer-based integration of user-uploaded photos and textual information into board and card games that feature such user-uploaded materials, and generate, from administrator-hosted templates, games and entertainment devices involving identification, reference and/or query based-response to such materials.
摘要翻译：一种娱乐，教育和商业方法，用于通过将用户上传的照片和文本信息通过计算机集成到具有这种用户上传的材料的板卡和纸牌游戏来创建游戏，并且从管理员托管的模板，游戏和娱乐设备生成涉及识别，参考和/或基于查询的响应。

7. 发明授权

US06508781B1 Ultrasonic ablation catheter transmission wire connector assembly 有权
标题翻译：超声波消融导管传输线连接器组件
公开(公告)号：US06508781B1
公开(公告)日：2003-01-21
申请号：US09476749
申请日：1999-12-30
申请人： Lawrence Brennan , Wayne E. Cornish , Douglas H. Gesswein , Martinos Tran
发明人： Lawrence Brennan , Wayne E. Cornish , Douglas H. Gesswein , Martinos Tran
IPC分类号： A61B1720
CPC分类号： A61B17/22012 , A61B2017/00477 , A61B2017/22015
摘要： An ultrasonic angioplasty device includes a catheter and a connector assembly for interconnecting an ultrasound transmission member to an ultrasound transducer. A rotation control device is provided that prevents the ultrasound transmission member from rotating relative to the catheter. Rotation is prevented by a fastener aligning the connector assembly with the elongated catheter body, or a key member that fits in a correspondingly shaped slot in a proximal shaft portion of the catheter, for preventing rotation of the connector assembly relative to the catheter.
摘要翻译：超声波血管成形术装置包括导管和用于将超声波传输构件与超声换能器互连的连接器组件。提供了一种防止超声波传输构件相对于导管旋转的旋转控制装置。通过紧固件将连接器组件与细长的导管主体或者配合在导管的近侧轴部分中的对应形状的槽中的键构件对齐，以防止连接器组件相对于导管的旋转来防止旋转。

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